[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"condition:chronic-myelomonocytic-leukemia":3},{"name":4,"total":5,"recruiting":6,"trials":7,"biomarkers":311,"states":327},"Chronic Myelomonocytic Leukemia",75,68,[8,16,23,29,36,42,48,54,60,66,72,78,83,89,95,101,107,114,121,127,133,139,145,151,157,163,169,175,181,187,193,199,205,211,217,223,229,235,241,248,254,260,266,272,278,284,290,295,300,305],{"nct_id":9,"title":10,"phases":11,"status":13,"updated_at":14,"content_modified":15},"NCT07064122","A Study of AZD2962, an IRAK4 Inhibitor (IRAK4 [a Body Protein] Blocker), in Participants With Haematologic Neoplasms (Blood Cancers)",[12],"Phase 1","RECRUITING","2026-08-26T02:17:11.311767Z","2026-05-05T02:43:29.350818Z",{"nct_id":17,"title":18,"phases":19,"status":13,"updated_at":21,"content_modified":22},"NCT04419649","A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS)",[20],"Phase 2","2026-08-26T02:15:54.846520Z","2026-05-05T02:43:29.043989Z",{"nct_id":24,"title":25,"phases":26,"status":13,"updated_at":27,"content_modified":28},"NCT06071624","Chimeric Antigen Receptor T Cell Therapy Redirected to CD4 (CD4CAR)as a Second Line Treatment for Chronic Myelomonocytic Leukemia, CMML.",[12],"2026-08-26T02:16:16.169331Z","2026-05-05T02:43:28.825591Z",{"nct_id":30,"title":31,"phases":32,"status":13,"updated_at":34,"content_modified":35},"NCT07128381","Phase I\u002FII Clinical Trial of Axatilimab, a CSF1R Monoclonal Antibody, in Combination With Ruxolitinib as Therapy for Patients With Myelofibrosis (MF) and Chronic Myelomonocytic Leukemia (CMML)",[33],"Phase 1\u002FPhase 2","2026-08-26T02:19:17.380174Z","2026-05-05T02:43:28.625623Z",{"nct_id":37,"title":38,"phases":39,"status":13,"updated_at":40,"content_modified":41},"NCT06159491","Pacritinib in CMML",[33],"2026-08-26T02:19:05.360997Z","2026-05-05T02:43:28.547100Z",{"nct_id":43,"title":44,"phases":45,"status":13,"updated_at":46,"content_modified":47},"NCT07033598","Pacritinib vs. Hydroxyurea in Advanced Proliferative Chronic Myelomonocytic Leukemia",[20],"2026-08-26T02:17:36.611194Z","2026-05-05T02:43:27.825848Z",{"nct_id":49,"title":50,"phases":51,"status":13,"updated_at":52,"content_modified":53},"NCT03896269","CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia",[12],"2026-08-26T02:17:16.980188Z","2026-05-05T02:43:27.095227Z",{"nct_id":55,"title":56,"phases":57,"status":13,"updated_at":58,"content_modified":59},"NCT06950034","A Phase 1 Study of STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML)",[12],"2026-08-26T02:19:11.399072Z","2026-05-05T02:35:31.860467Z",{"nct_id":61,"title":62,"phases":63,"status":13,"updated_at":64,"content_modified":65},"NCT05442216","Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents",[20],"2026-08-26T02:16:13.426928Z","2026-07-19T19:36:05.118087Z",{"nct_id":67,"title":68,"phases":69,"status":13,"updated_at":70,"content_modified":71},"NCT06566742","A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic\u002FSyndromes\u002FChronic Myelomonocytic Leukemia.",[20],"2026-08-26T02:18:38.077159Z","2026-07-19T19:36:05.036073Z",{"nct_id":73,"title":74,"phases":75,"status":13,"updated_at":76,"content_modified":77},"NCT03850418","Azacitidine and Chimerism in MDS or AML Patients After Allogeneic Stem Cell Transplant",[20],"2026-08-26T02:18:02.701182Z","2026-05-29T15:36:40.172582Z",{"nct_id":79,"title":80,"phases":81,"status":13,"updated_at":34,"content_modified":82},"NCT07582172","Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome",[20],"2026-05-13T02:55:06.792892Z",{"nct_id":84,"title":85,"phases":86,"status":13,"updated_at":87,"content_modified":88},"NCT06668584","A Phase II Open-label Study of Olutasidenib Post-transplant Maintenance Therapy for Patients With IDH1-mutated Myeloid Malignancies",[20],"2026-08-26T02:19:02.550788Z","2026-05-05T02:47:14.264276Z",{"nct_id":90,"title":91,"phases":92,"status":13,"updated_at":93,"content_modified":94},"NCT03418038","Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia",[20],"2026-08-26T02:15:21.365312Z","2026-05-05T02:43:29.732946Z",{"nct_id":96,"title":97,"phases":98,"status":13,"updated_at":99,"content_modified":100},"NCT06930651","A Phase I\u002FII Study of CAR.70-Engineered IL15-Transduced Cord Blood-Derived NK Cells With TGF-beta Receptor 2 (TGFBR2) Knock Out in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed\u002FRefractory Myeloid Malignancies",[33],"2026-08-26T02:18:33.598205Z","2026-05-05T02:43:29.673718Z",{"nct_id":102,"title":103,"phases":104,"status":13,"updated_at":105,"content_modified":106},"NCT06383572","Phase I\u002FII Study of Engineered T Cell Receptor-Modified NK Cells Targeting PRAME in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse\u002FRefractory Myeloid Malignancies",[33],"2026-08-26T02:15:50.539717Z","2026-05-05T02:43:29.502354Z",{"nct_id":108,"title":109,"phases":110,"status":13,"updated_at":112,"content_modified":113},"NCT07071155","Momelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes\u002FMyeloproliferative Overlap Neoplasms and Chronic Neutrophilic Leukemia",[111],"Early Phase 1","2026-08-26T02:15:27.567165Z","2026-05-05T02:43:29.411655Z",{"nct_id":115,"title":116,"phases":117,"status":13,"updated_at":119,"content_modified":120},"NCT04708054","Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS",[118],"Phase 2\u002FPhase 3","2026-08-26T02:17:58.890423Z","2026-05-05T02:43:29.214501Z",{"nct_id":122,"title":123,"phases":124,"status":13,"updated_at":125,"content_modified":126},"NCT03850574","Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia",[33],"2026-08-26T02:15:33.331531Z","2026-05-05T02:43:28.985956Z",{"nct_id":128,"title":129,"phases":130,"status":13,"updated_at":131,"content_modified":132},"NCT06502145","Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic Syndrome",[12],"2026-08-26T02:18:51.009190Z","2026-05-05T02:43:28.852980Z",{"nct_id":134,"title":135,"phases":136,"status":13,"updated_at":137,"content_modified":138},"NCT05549661","Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome\u002FMPN Overlap Neoplasms",[12],"2026-08-26T02:15:53.461103Z","2026-05-05T02:43:28.622435Z",{"nct_id":140,"title":141,"phases":142,"status":13,"updated_at":143,"content_modified":144},"NCT04239157","A Phase II, Open-Label, Study of Subcutaneous Canakinumab, an Anti-IL-1β Human Monoclonal Antibody, for Patients With Low or Int-1 Risk IPSS\u002FIPSS-R Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia",[20],"2026-08-26T02:16:46.147215Z","2026-05-05T02:43:28.559765Z",{"nct_id":146,"title":147,"phases":148,"status":13,"updated_at":149,"content_modified":150},"NCT05365035","A Phase II Study of Cladribine and Low Dose Cytarabine in Combination With Venetoclax, Alternating With Azacitidine and Venetoclax, in Patients With Higher-risk Myeloproliferative Chronic Myelomonocytic Leukemia or Higher-risk Myelodysplastic Syndromes With Excess Blasts",[20],"2026-08-26T02:16:21.385056Z","2026-05-05T02:43:27.978920Z",{"nct_id":152,"title":153,"phases":154,"status":13,"updated_at":155,"content_modified":156},"NCT05488548","Dual BET and CBP\u002Fp300 Inhibitor in Patients With Targeted Advanced Solid Tumors and Hematological Malignancies",[12],"2026-08-26T02:16:57.705506Z","2026-05-05T02:43:27.844024Z",{"nct_id":158,"title":159,"phases":160,"status":13,"updated_at":161,"content_modified":162},"NCT06994676","A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias",[12],"2026-08-26T02:18:41.390601Z","2026-05-05T02:43:27.517921Z",{"nct_id":164,"title":165,"phases":166,"status":13,"updated_at":167,"content_modified":168},"NCT04256317","A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)",[118],"2026-08-26T02:19:19.975067Z","2026-05-05T02:43:27.295869Z",{"nct_id":170,"title":171,"phases":172,"status":13,"updated_at":173,"content_modified":174},"NCT04996875","(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis",[20],"2026-08-26T02:15:23.202838Z","2026-05-05T02:43:27.251075Z",{"nct_id":176,"title":177,"phases":178,"status":13,"updated_at":179,"content_modified":180},"NCT04375631","CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia",[12],"2026-08-26T02:16:22.235886Z","2026-05-05T02:43:26.964811Z",{"nct_id":182,"title":183,"phases":184,"status":13,"updated_at":185,"content_modified":186},"NCT06973668","A Randomized Study to Compare Post-transplant Cyclophosphamide, Sirolimus, Ruxolitinib and Post-transplant Cyclophosphamide, Sirolimus, Mycophenolate Mofetil to Prevent Graft Versus Host Disease",[20],"2026-08-26T02:15:41.377360Z","2026-05-05T02:43:26.945363Z",{"nct_id":188,"title":189,"phases":190,"status":13,"updated_at":191,"content_modified":192},"NCT03383575","Azacitidine and Enasidenib in Treating Patients With IDH2-Mutant Myelodysplastic Syndrome",[20],"2026-08-26T02:15:25.633039Z","2026-05-05T02:43:26.928444Z",{"nct_id":194,"title":195,"phases":196,"status":13,"updated_at":197,"content_modified":198},"NCT07046078","Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer",[20],"2026-08-26T02:19:25.538428Z","2026-05-05T02:35:31.876787Z",{"nct_id":200,"title":201,"phases":202,"status":13,"updated_at":203,"content_modified":204},"NCT07249346","Dose-Expansion Study of Low Dose Post-Transplant Cyclophosphamide\u002FTacrolimus\u002FRuxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxis in Myeloablative Allogeneic Peripheral Blood Stem Cell Transplantation",[20],"2026-08-26T02:17:56.243868Z","2026-05-05T02:35:31.751095Z",{"nct_id":206,"title":207,"phases":208,"status":13,"updated_at":209,"content_modified":210},"NCT05184842","Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine\u002FVenetoclax in MDS and AML",[20],"2026-08-26T02:15:31.806698Z","2026-05-05T02:35:31.749361Z",{"nct_id":212,"title":213,"phases":214,"status":13,"updated_at":215,"content_modified":216},"NCT06543381","Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant",[12],"2026-08-26T02:15:01.639696Z","2026-04-29T02:57:57.159415Z",{"nct_id":218,"title":219,"phases":220,"status":13,"updated_at":221,"content_modified":222},"NCT04140487","Azacitidine, Venetoclax, and Gilteritinib in Treating Patients With Recurrent\u002FRefractory FLT3-Mutated Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or High-Risk Myelodysplastic Syndrome\u002FMyeloproliferative Neoplasm",[33],"2026-08-26T02:18:31.164304Z","2026-04-29T02:57:57.109829Z",{"nct_id":224,"title":225,"phases":226,"status":13,"updated_at":227,"content_modified":228},"NCT05342584","Venetoclax Plus Intensive Chemotherapy in AML and Advanced MDS",[12],"2026-08-26T02:16:52.995882Z","2026-04-29T02:57:57.107474Z",{"nct_id":230,"title":231,"phases":232,"status":13,"updated_at":233,"content_modified":234},"NCT05320198","Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia",[33],"2026-08-26T02:18:53.782384Z","2026-07-24T01:27:14.872106Z",{"nct_id":236,"title":237,"phases":238,"status":13,"updated_at":239,"content_modified":240},"NCT03670966","211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome",[33],"2026-08-26T02:17:52.450442Z","2026-07-05T05:32:16.772513Z",{"nct_id":242,"title":243,"phases":244,"status":13,"updated_at":246,"content_modified":247},"NCT06615050","A Study of Tacrolimus\u002FMethotrexate\u002FRuxolitinib Versus Post-Transplant Cyclophosphamide\u002FTacrolimus\u002FMycophenolate Mofetil in Non-Myeloablative\u002FReduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)",[245],"Phase 3","2026-08-26T02:16:04.914942Z","2026-07-05T05:32:16.764159Z",{"nct_id":249,"title":250,"phases":251,"status":13,"updated_at":252,"content_modified":253},"NCT06928662","Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse",[33],"2026-08-26T02:16:39.977107Z","2026-07-05T05:32:16.705622Z",{"nct_id":255,"title":256,"phases":257,"status":13,"updated_at":258,"content_modified":259},"NCT06315309","Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant",[20],"2026-08-26T02:16:48.735701Z","2026-05-05T02:43:29.662218Z",{"nct_id":261,"title":262,"phases":263,"status":13,"updated_at":264,"content_modified":265},"NCT05470491","Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...",[33],"2026-08-26T02:17:35.666428Z","2026-05-05T02:43:29.587324Z",{"nct_id":267,"title":268,"phases":269,"status":13,"updated_at":270,"content_modified":271},"NCT06712810","Q702 for the Treatment of Patients With Hematologic Malignancies",[12],"2026-08-26T02:16:20.336282Z","2026-05-05T02:43:29.581486Z",{"nct_id":273,"title":274,"phases":275,"status":13,"updated_at":276,"content_modified":277},"NCT05031897","Two Step Haplo With Radiation Conditioning",[20],"2026-08-26T02:16:32.589113Z","2026-05-05T02:43:29.158573Z",{"nct_id":279,"title":280,"phases":281,"status":13,"updated_at":282,"content_modified":283},"NCT06807606","Optimized Cord Blood Transplantation for the Treatment of Patients With High-risk Hematologic Malignancies Who Have Relapsed After First Allogeneic Stem Cell Transplantation",[20],"2026-08-26T02:17:30.961790Z","2026-05-05T02:43:29.132814Z",{"nct_id":285,"title":286,"phases":287,"status":13,"updated_at":288,"content_modified":289},"NCT06680661","ABBA CORD: dCBT w\u002F Abatacept for aGVHD Prophylaxis",[20],"2026-08-26T02:17:14.343713Z","2026-05-05T02:43:28.824003Z",{"nct_id":291,"title":292,"phases":293,"status":13,"updated_at":209,"content_modified":294},"NCT06859424","A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation",[20],"2026-05-05T02:43:28.740200Z",{"nct_id":296,"title":297,"phases":298,"status":13,"updated_at":173,"content_modified":299},"NCT04959175","Phase I\u002FII Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies",[33],"2026-05-05T02:43:28.644953Z",{"nct_id":301,"title":302,"phases":303,"status":13,"updated_at":46,"content_modified":304},"NCT06815003","Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning",[20],"2026-05-05T02:43:28.124047Z",{"nct_id":306,"title":307,"phases":308,"status":13,"updated_at":309,"content_modified":310},"NCT06523556","Axatilimab With or Without Azacitidine for the Treatment of Patients With Advanced Phase Myeloproliferative Neoplasms, Myeloproliferative Neoplasm\u002FMyelodysplastic Syndrome Overlap or High Risk Chronic Myelomonocytic Leukemia",[33],"2026-08-26T02:18:26.129155Z","2026-05-05T02:43:27.949132Z",[312,316,320,324],{"biomarker":313,"count":314,"slug":315},"HLA Complex",6,"hla-complex",{"biomarker":317,"count":318,"slug":319},"IDH1 Gene",5,"idh1-gene",{"biomarker":321,"count":322,"slug":323},"HLA Class I Histocompatibility Antigen, A-0201 Alpha Chain",3,"hla-class-i-histocompatibility-antigen-a-0201-alpha-chain",{"biomarker":325,"count":322,"slug":326},"IDH2 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