[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"condition:chronic-obstructive-pulmonary-disease":3},{"name":4,"total":5,"recruiting":6,"trials":7,"biomarkers":308,"states":320},"Chronic Obstructive Pulmonary Disease",137,102,[8,16,23,30,36,42,48,54,60,67,74,80,86,92,98,104,110,116,122,128,135,141,147,153,159,165,171,177,183,189,195,201,207,212,218,224,229,234,239,245,251,257,263,268,274,280,286,291,297,303],{"nct_id":9,"title":10,"phases":11,"status":13,"updated_at":14,"content_modified":15},"NCT07610395","Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD",[12],"Phase 2","RECRUITING","2026-08-26T02:18:06.247899Z","2026-07-05T05:32:16.641749Z",{"nct_id":17,"title":18,"phases":19,"status":13,"updated_at":21,"content_modified":22},"NCT06944925","A Study of BBT002 in Healthy Volunteers (HVs) and in Adult Patients With Chronic Obstructive Pulmonary Disease (COPD) or Chronic Rhiosininusitis With Nasal Polyps (CRSwNP)",[20],"Phase 1","2026-08-26T02:18:36.226508Z","2026-07-05T03:45:20.249454Z",{"nct_id":24,"title":25,"phases":26,"status":13,"updated_at":28,"content_modified":29},"NCT06961214","Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)",[27],"Phase 3","2026-08-26T02:16:38.053590Z","2026-05-05T02:43:29.666834Z",{"nct_id":31,"title":32,"phases":33,"status":13,"updated_at":34,"content_modified":35},"NCT06634810","Comprehensive Patient-Centered Home-based Care Coaching for COPD Self-management",[],"2026-08-26T02:19:27.519777Z","2026-05-05T02:43:29.578946Z",{"nct_id":37,"title":38,"phases":39,"status":13,"updated_at":40,"content_modified":41},"NCT04179981","Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)",[],"2026-08-26T02:17:30.961790Z","2026-05-05T02:43:29.531060Z",{"nct_id":43,"title":44,"phases":45,"status":13,"updated_at":46,"content_modified":47},"NCT06283966","A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease",[27],"2026-08-26T02:17:09.131534Z","2026-05-05T02:43:29.527616Z",{"nct_id":49,"title":50,"phases":51,"status":13,"updated_at":52,"content_modified":53},"NCT07190222","Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype",[27],"2026-08-26T02:19:28.327680Z","2026-05-05T02:43:29.507330Z",{"nct_id":55,"title":56,"phases":57,"status":13,"updated_at":58,"content_modified":59},"NCT06432972","Accelerated Pulmonary Rehabilitation in the Preoperative Period",[],"2026-08-26T02:18:29.369233Z","2026-05-05T02:43:29.504189Z",{"nct_id":61,"title":62,"phases":63,"status":13,"updated_at":65,"content_modified":66},"NCT06603246","A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease",[64],"Phase 1\u002FPhase 2","2026-08-26T02:18:43.501109Z","2026-05-05T02:43:29.473813Z",{"nct_id":68,"title":69,"phases":70,"status":13,"updated_at":72,"content_modified":73},"NCT07053423","A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.",[71],"Phase 4","2026-08-26T02:16:44.178623Z","2026-05-05T02:43:29.471924Z",{"nct_id":75,"title":76,"phases":77,"status":13,"updated_at":78,"content_modified":79},"NCT05701982","The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain",[],"2026-08-26T02:19:01.741747Z","2026-05-05T02:43:29.285481Z",{"nct_id":81,"title":82,"phases":83,"status":13,"updated_at":84,"content_modified":85},"NCT07051707","Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD",[],"2026-08-26T02:16:48.735701Z","2026-05-05T02:43:29.210963Z",{"nct_id":87,"title":88,"phases":89,"status":13,"updated_at":90,"content_modified":91},"NCT07125053","COPD Resources, Education, and Activity Designed for You Study",[],"2026-08-26T02:17:10.213717Z","2026-05-05T02:43:29.167574Z",{"nct_id":93,"title":94,"phases":95,"status":13,"updated_at":96,"content_modified":97},"NCT04801108","Combined Zephyr Valve System With Inter-lobar Fissure Completion for Lung Volume Reduction in Emphysema",[],"2026-08-26T02:16:52.995882Z","2026-05-05T02:43:29.166276Z",{"nct_id":99,"title":100,"phases":101,"status":13,"updated_at":102,"content_modified":103},"NCT05270525","Effect of Ensifentrine on Sputum Markers of Inflammation in COPD",[12],"2026-08-26T02:17:48.768272Z","2026-05-05T02:43:28.985501Z",{"nct_id":105,"title":106,"phases":107,"status":13,"updated_at":108,"content_modified":109},"NCT06578156","Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD",[],"2026-08-26T02:19:08.862440Z","2026-05-05T02:43:28.819109Z",{"nct_id":111,"title":112,"phases":113,"status":13,"updated_at":114,"content_modified":115},"NCT06600126","Supporting Evidence-based Responses to Emotional Needs in Emphysema",[],"2026-08-26T02:17:55.355429Z","2026-05-05T02:43:28.672478Z",{"nct_id":117,"title":118,"phases":119,"status":13,"updated_at":120,"content_modified":121},"NCT07072039","Evaluation of the Paramedic Evaluation for Acute COPD Exacerbation",[],"2026-08-26T02:18:51.009190Z","2026-05-05T02:43:28.644718Z",{"nct_id":123,"title":124,"phases":125,"status":13,"updated_at":126,"content_modified":127},"NCT05934565","Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF",[],"2026-08-26T02:15:53.461103Z","2026-05-05T02:43:28.476104Z",{"nct_id":129,"title":130,"phases":131,"status":13,"updated_at":133,"content_modified":134},"NCT07363694","A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease",[132],"Phase 2\u002FPhase 3","2026-08-26T02:19:19.975067Z","2026-05-05T02:43:28.403022Z",{"nct_id":136,"title":137,"phases":138,"status":13,"updated_at":139,"content_modified":140},"NCT07177339","eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation",[27],"2026-08-26T02:19:11.399072Z","2026-05-05T02:43:27.980156Z",{"nct_id":142,"title":143,"phases":144,"status":13,"updated_at":145,"content_modified":146},"NCT07133880","Compare the Effects of Nebulizer Versus Inhaler Based Therapy for COPD Using Long-acting Bronchodilators",[71],"2026-08-26T02:16:07.529922Z","2026-05-05T02:43:27.658815Z",{"nct_id":148,"title":149,"phases":150,"status":13,"updated_at":151,"content_modified":152},"NCT07059091","Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD",[12],"2026-08-26T02:16:20.336282Z","2026-05-05T02:43:27.641238Z",{"nct_id":154,"title":155,"phases":156,"status":13,"updated_at":157,"content_modified":158},"NCT06878261","A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)",[27],"2026-08-26T02:18:48.678868Z","2026-05-05T02:43:27.608206Z",{"nct_id":160,"title":161,"phases":162,"status":13,"updated_at":163,"content_modified":164},"NCT07119229","A Multi Center Study Testing a New Implant for Adults With Severe Emphysema",[],"2026-08-26T02:17:54.420226Z","2026-05-05T02:43:27.436169Z",{"nct_id":166,"title":167,"phases":168,"status":13,"updated_at":169,"content_modified":170},"NCT07037836","Inhaled Treprostinil (Tyvaso Nebulizer) For COPD Patients With Hypoxemia",[12],"2026-08-26T02:15:56.561131Z","2026-05-05T02:43:27.431607Z",{"nct_id":172,"title":173,"phases":174,"status":13,"updated_at":175,"content_modified":176},"NCT06035120","An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema",[],"2026-08-26T02:15:31.806698Z","2026-05-05T02:43:27.425087Z",{"nct_id":178,"title":179,"phases":180,"status":13,"updated_at":181,"content_modified":182},"NCT05204888","myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home",[],"2026-08-26T02:19:07.104270Z","2026-05-05T02:43:27.284627Z",{"nct_id":184,"title":185,"phases":186,"status":13,"updated_at":187,"content_modified":188},"NCT07404826","PEP Buddy in Pulmonary Rehabilitation",[],"2026-08-26T02:19:14.560989Z","2026-05-05T02:43:27.256145Z",{"nct_id":190,"title":191,"phases":192,"status":13,"updated_at":193,"content_modified":194},"NCT06152653","The Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM)",[71],"2026-08-03T02:21:37.915430Z","2026-05-05T02:43:27.248685Z",{"nct_id":196,"title":197,"phases":198,"status":13,"updated_at":199,"content_modified":200},"NCT06496620","A Study to Evaluate Solrikitug in Participants With COPD (ZION)",[12],"2026-08-03T03:39:05.349687Z","2026-05-05T02:43:27.088438Z",{"nct_id":202,"title":203,"phases":204,"status":13,"updated_at":205,"content_modified":206},"NCT05878769","A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)",[27],"2026-08-03T03:29:04.388436Z","2026-05-05T02:43:26.915882Z",{"nct_id":208,"title":209,"phases":210,"status":13,"updated_at":139,"content_modified":211},"NCT05257681","Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction",[],"2026-05-05T02:43:26.770178Z",{"nct_id":213,"title":214,"phases":215,"status":13,"updated_at":216,"content_modified":217},"NCT06883305","A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)",[27],"2026-08-26T02:15:28.524219Z","2026-05-05T02:43:26.682229Z",{"nct_id":219,"title":220,"phases":221,"status":13,"updated_at":222,"content_modified":223},"NCT06891755","Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3",[],"2026-08-26T02:16:21.385056Z","2026-05-05T02:35:31.877632Z",{"nct_id":225,"title":226,"phases":227,"status":13,"updated_at":72,"content_modified":228},"NCT07222410","Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital",[],"2026-05-05T02:35:31.871802Z",{"nct_id":230,"title":231,"phases":232,"status":13,"updated_at":163,"content_modified":233},"NCT07190209","Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype",[27],"2026-05-05T02:35:31.713460Z",{"nct_id":235,"title":236,"phases":237,"status":13,"updated_at":108,"content_modified":238},"NCT06959095","Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA -1)",[27],"2026-05-05T02:35:31.688782Z",{"nct_id":240,"title":241,"phases":242,"status":13,"updated_at":243,"content_modified":244},"NCT05265299","Trial to Determine Effective Aspirin Dose in COPD",[27],"2026-08-26T02:19:00.742020Z","2026-04-29T02:57:57.157267Z",{"nct_id":246,"title":247,"phases":248,"status":13,"updated_at":249,"content_modified":250},"NCT07082738","A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease",[12],"2026-08-26T02:18:19.586423Z","2026-04-29T02:57:57.081376Z",{"nct_id":252,"title":253,"phases":254,"status":13,"updated_at":255,"content_modified":256},"NCT05937854","Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH",[12],"2026-08-26T02:16:12.203827Z","2026-07-05T05:32:16.737630Z",{"nct_id":258,"title":259,"phases":260,"status":13,"updated_at":261,"content_modified":262},"NCT07576894","Right Ventricular Response to Exercise Among Patients With Chronic Obstructive Pulmonary Disease",[],"2026-08-26T02:19:29.119921Z","2026-05-13T02:55:06.780586Z",{"nct_id":264,"title":265,"phases":266,"status":13,"updated_at":52,"content_modified":267},"NCT02703207","Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD",[],"2026-05-05T02:43:29.526207Z",{"nct_id":269,"title":270,"phases":271,"status":13,"updated_at":272,"content_modified":273},"NCT06390345","Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention",[],"2026-08-26T02:18:04.640417Z","2026-05-05T02:43:28.865170Z",{"nct_id":275,"title":276,"phases":277,"status":13,"updated_at":278,"content_modified":279},"NCT05237505","The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome)",[12],"2026-08-26T02:16:54.876240Z","2026-05-05T02:43:28.659910Z",{"nct_id":281,"title":282,"phases":283,"status":13,"updated_at":284,"content_modified":285},"NCT05746039","Feasibility of Semaglutide in Advanced Lung Disease",[64],"2026-08-26T02:15:51.395565Z","2026-05-05T02:43:27.598354Z",{"nct_id":287,"title":288,"phases":289,"status":13,"updated_at":133,"content_modified":290},"NCT07059637","Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD",[],"2026-05-05T02:43:27.593946Z",{"nct_id":292,"title":293,"phases":294,"status":13,"updated_at":295,"content_modified":296},"NCT03500731","Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure",[64],"2026-08-26T02:16:24.135291Z","2026-05-05T02:43:26.906541Z",{"nct_id":298,"title":299,"phases":300,"status":13,"updated_at":301,"content_modified":302},"NCT03524222","Home Hospital for Suddenly Ill Adults",[],"2026-08-26T02:17:45.190188Z","2026-05-05T02:43:28.711779Z",{"nct_id":304,"title":305,"phases":306,"status":13,"updated_at":58,"content_modified":307},"NCT05733767","Smoking Cessation Pharmacotherapy-Nurse Practitioner Led Tobacco Treatment Team Study",[12],"2026-05-05T02:35:31.774833Z",[309,313,317],{"biomarker":310,"count":311,"slug":312},"Eosinophilia",4,"eosinophilia",{"biomarker":314,"count":315,"slug":316},"Eosinophil Count",3,"eosinophil-count",{"biomarker":318,"count":315,"slug":319},"IKAROS FAMILY ZINC FINGER 4","ikaros-family-zinc-finger-4",[321,325,329,333,337,341,345,349,353,357,361,364,368,371,375,379,382,386,389,393,397,401,405,408],{"state":322,"count":323,"slug":324},"Pennsylvania",40,"pennsylvania",{"state":326,"count":327,"slug":328},"California",37,"california",{"state":330,"count":331,"slug":332},"Florida",34,"florida",{"state":334,"count":335,"slug":336},"Texas",33,"texas",{"state":338,"count":339,"slug":340},"North Carolina",32,"north-carolina",{"state":342,"count":343,"slug":344},"Massachusetts",31,"massachusetts",{"state":346,"count":347,"slug":348},"New York",28,"new-york",{"state":350,"count":351,"slug":352},"Michigan",26,"michigan",{"state":354,"count":355,"slug":356},"Alabama",25,"alabama",{"state":358,"count":359,"slug":360},"Arizona",23,"arizona",{"state":362,"count":359,"slug":363},"Illinois","illinois",{"state":365,"count":366,"slug":367},"Georgia",21,"georgia",{"state":369,"count":366,"slug":370},"South Carolina","south-carolina",{"state":372,"count":373,"slug":374},"Maryland",20,"maryland",{"state":376,"count":377,"slug":378},"Colorado",19,"colorado",{"state":380,"count":377,"slug":381},"Ohio","ohio",{"state":383,"count":384,"slug":385},"Tennessee",18,"tennessee",{"state":387,"count":384,"slug":388},"Virginia","virginia",{"state":390,"count":391,"slug":392},"Indiana",14,"indiana",{"state":394,"count":395,"slug":396},"Louisiana",13,"louisiana",{"state":398,"count":399,"slug":400},"Kansas",12,"kansas",{"state":402,"count":403,"slug":404},"Minnesota",11,"minnesota",{"state":406,"count":403,"slug":407},"Nevada","nevada",{"state":409,"count":403,"slug":410},"Oklahoma","oklahoma"]