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Cancer",[12],"2026-08-26T02:18:59.761994Z","2026-05-05T02:43:29.164625Z",{"nct_id":42,"title":43,"phases":44,"status":13,"updated_at":45,"content_modified":46},"NCT04018872","Evaluating the Effect of Itraconazole on Pathologic Complete Response Rates in Esophageal Cancer",[26],"2026-08-26T02:18:06.247899Z","2026-05-05T02:43:28.803839Z",{"nct_id":48,"title":49,"phases":50,"status":13,"updated_at":51,"content_modified":52},"NCT07475286","Combined Systemic and Intraperitoneal Chemotherapy for Synchronous Gastric and\u002For Gastroesophageal Peritoneal Carcinomatosis",[26],"2026-08-26T02:15:33.331531Z","2026-05-05T02:43:28.624348Z",{"nct_id":54,"title":55,"phases":56,"status":13,"updated_at":57,"content_modified":58},"NCT04656041","Folfox+Irinotecan+Chemort In Esophageal Cancer",[26],"2026-08-26T02:15:56.561131Z","2026-05-05T02:43:28.406573Z",{"nct_id":60,"title":61,"phases":62,"status":13,"updated_at":64,"content_modified":65},"NCT04511039","Trifluridine\u002FTipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer",[63],"Phase 1","2026-08-26T02:17:02.694423Z","2026-05-05T02:43:28.371416Z",{"nct_id":67,"title":68,"phases":69,"status":13,"updated_at":70,"content_modified":71},"NCT06038578","A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer",[26],"2026-08-26T02:19:14.560989Z","2026-05-05T02:43:28.134289Z",{"nct_id":73,"title":74,"phases":75,"status":13,"updated_at":76,"content_modified":77},"NCT06532006","A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer",[12],"2026-08-26T02:17:06.985283Z","2026-05-05T02:43:28.114299Z",{"nct_id":79,"title":80,"phases":81,"status":13,"updated_at":82,"content_modified":83},"NCT05651594","Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma",[26],"2026-08-26T02:19:29.119921Z","2026-05-05T02:43:27.948442Z",{"nct_id":85,"title":86,"phases":87,"status":13,"updated_at":88,"content_modified":89},"NCT06078709","Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma",[26],"2026-08-26T02:17:16.126291Z","2026-05-05T02:43:27.662839Z",{"nct_id":91,"title":92,"phases":93,"status":13,"updated_at":95,"content_modified":96},"NCT06841679","Utidelone Capsule Combined With Fluoropyrimidine- and Platinum-containing Therapy in First-line Treatment of Patients With Gastric or Gastroesophageal Junction Adenocarcinoma",[94],"Phase 2\u002FPhase 3","2026-08-26T02:18:05.435729Z","2026-05-05T02:43:27.076939Z",{"nct_id":98,"title":99,"phases":100,"status":13,"updated_at":101,"content_modified":102},"NCT04660760","Ramucirumab and Trifluridine\u002FTipiracil or Paclitaxel for the Treatment of Patients With Previously Treated 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Chemo and\u002For ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)",[119],"Phase 1\u002FPhase 2","2026-08-26T02:16:36.513735Z","2026-07-19T19:36:05.117317Z",{"nct_id":123,"title":124,"phases":125,"status":13,"updated_at":126,"content_modified":127},"NCT05365581","A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer",[63],"2026-08-26T02:17:42.501124Z","2026-07-05T05:32:16.805238Z",{"nct_id":129,"title":130,"phases":131,"status":13,"updated_at":132,"content_modified":133},"NCT05277168","A TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF SHR-A1904 IN SUBJECTS WITH ADVANCED SOLID TUMORS",[119],"2026-08-26T02:17:55.355429Z","2026-07-05T05:32:16.798807Z",{"nct_id":135,"title":136,"phases":137,"status":13,"updated_at":138,"content_modified":139},"NCT06663319","A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers",[63],"2026-08-26T02:17:40.683658Z","2026-07-05T05:32:16.768691Z",{"nct_id":141,"title":142,"phases":143,"status":13,"updated_at":144,"content_modified":145},"NCT07221149","A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)",[94],"2026-08-26T02:16:38.053590Z","2026-07-05T05:32:16.664938Z",{"nct_id":147,"title":148,"phases":149,"status":13,"updated_at":150,"content_modified":151},"NCT05332002","sFOLFOXIRI in Advanced Gastroesophageal Cancer, 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Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial",[94],"2026-08-26T02:17:28.381459Z","2026-05-05T02:43:28.966545Z",{"nct_id":171,"title":172,"phases":173,"status":13,"updated_at":174,"content_modified":175},"NCT07069712","A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma",[26],"2026-08-26T02:19:12.219640Z","2026-05-05T02:43:28.835650Z",{"nct_id":177,"title":178,"phases":179,"status":13,"updated_at":180,"content_modified":181},"NCT04379596","Ph1b\u002F2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)",[26],"2026-08-26T02:16:13.426928Z","2026-05-05T02:43:28.509515Z",{"nct_id":183,"title":184,"phases":185,"status":13,"updated_at":186,"content_modified":187},"NCT06364410","Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors",[63],"2026-08-26T02:17:58.890423Z","2026-05-05T02:43:28.188138Z",{"nct_id":189,"title":190,"phases":191,"status":13,"updated_at":192,"content_modified":193},"NCT03801876","Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer",[12],"2026-08-03T02:53:22.686520Z","2026-05-05T02:43:28.114487Z",{"nct_id":195,"title":196,"phases":197,"status":13,"updated_at":198,"content_modified":199},"NCT05677490","mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma",[12],"2026-08-26T02:16:44.178623Z","2026-05-05T02:43:27.998780Z",{"nct_id":201,"title":202,"phases":203,"status":13,"updated_at":204,"content_modified":205},"NCT07001748","Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity",[94],"2026-08-26T02:15:43.339060Z","2026-05-05T02:43:27.952061Z",{"nct_id":207,"title":208,"phases":209,"status":13,"updated_at":174,"content_modified":210},"NCT06445972","Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D\u002FKeymaker-U06)",[119],"2026-05-05T02:43:27.630303Z",{"nct_id":212,"title":213,"phases":214,"status":13,"updated_at":215,"content_modified":216},"NCT05187182","CA-4948 in Combination With FOLFOX\u002FPD-1 Inhibitor +\u002F- Trastuzumab for Untreated Unresectable Gastric and Esophageal Cancer",[63],"2026-08-26T02:18:20.384845Z","2026-05-05T02:43:26.773275Z",{"nct_id":218,"title":219,"phases":220,"status":13,"updated_at":221,"content_modified":222},"NCT06340711","Study of Suratadenoturev (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma",[26],"2026-08-26T02:17:22.949982Z","2026-05-05T02:43:26.706643Z",{"nct_id":224,"title":225,"phases":226,"status":13,"updated_at":27,"content_modified":227},"NCT07392892","A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer",[94],"2026-04-29T02:57:57.159659Z",{"nct_id":229,"title":230,"phases":231,"status":13,"updated_at":88,"content_modified":232},"NCT03526835","A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors",[119],"2026-07-30T01:46:14.461456Z",{"nct_id":234,"title":235,"phases":236,"status":13,"updated_at":237,"content_modified":238},"NCT07070232","A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors",[119],"2026-08-26T02:18:30.351130Z","2026-07-24T01:27:14.894336Z",{"nct_id":240,"title":241,"phases":242,"status":13,"updated_at":243,"content_modified":244},"NCT06293898","Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors",[63],"2026-08-26T02:16:23.080181Z","2026-07-24T01:27:14.888332Z",{"nct_id":246,"title":247,"phases":248,"status":13,"updated_at":249,"content_modified":250},"NCT07186842","A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9",[119],"2026-08-26T02:15:27.567165Z","2026-07-19T19:36:05.067561Z",{"nct_id":252,"title":253,"phases":254,"status":13,"updated_at":255,"content_modified":256},"NCT05872295","IKS014 in Advanced Solid Tumors That Express HER2",[63],"2026-08-26T02:19:16.454910Z","2026-07-05T05:32:16.816198Z",{"nct_id":258,"title":259,"phases":260,"status":13,"updated_at":180,"content_modified":261},"NCT06384352","Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors",[63],"2026-07-05T05:32:16.752089Z",{"nct_id":263,"title":264,"phases":265,"status":13,"updated_at":266,"content_modified":267},"NCT06789172","A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors",[63],"2026-08-26T02:16:18.872924Z","2026-07-05T05:32:16.698119Z",{"nct_id":269,"title":270,"phases":271,"status":13,"updated_at":272,"content_modified":273},"NCT07454642","AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors",[63],"2026-08-26T02:15:39.267524Z","2026-07-05T05:32:16.683506Z",{"nct_id":275,"title":276,"phases":277,"status":13,"updated_at":278,"content_modified":279},"NCT07287995","A Study of ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors",[119],"2026-08-26T02:19:11.399072Z","2026-07-05T05:32:16.680665Z",{"nct_id":281,"title":282,"phases":283,"status":13,"updated_at":284,"content_modified":285},"NCT07277413","A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors",[63],"2026-08-26T02:16:01.910993Z","2026-07-05T05:32:16.679197Z",{"nct_id":287,"title":288,"phases":289,"status":13,"updated_at":290,"content_modified":291},"NCT04895709","A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors",[119],"2026-08-26T02:19:00.742020Z","2026-06-16T05:54:07.907527Z",{"nct_id":293,"title":294,"phases":295,"status":13,"updated_at":57,"content_modified":296},"NCT07115043","A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors",[119],"2026-05-05T02:43:29.700642Z",{"nct_id":298,"title":299,"phases":300,"status":13,"updated_at":301,"content_modified":302},"NCT05902988","A Phase I\u002FII Study of VLS-1488 in Subjects With Advanced Cancer",[119],"2026-08-26T02:17:13.277148Z","2026-05-05T02:43:29.683485Z",{"nct_id":304,"title":305,"phases":306,"status":13,"updated_at":307,"content_modified":308},"NCT05584670","A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors",[119],"2026-08-26T02:18:35.425468Z","2026-05-05T02:43:29.645288Z",[310,314,318,322,326],{"biomarker":311,"count":312,"slug":313},"Programmed Cell Death 1 Ligand 1",15,"programmed-cell-death-1-ligand-1",{"biomarker":315,"count":316,"slug":317},"ERBB2 Gene",10,"erbb2-gene",{"biomarker":319,"count":320,"slug":321},"MSI1 Gene",8,"msi1-gene",{"biomarker":323,"count":324,"slug":325},"Claudin-18 Isoform A2",7,"claudin-18-isoform-a2",{"biomarker":327,"count":328,"slug":329},"MRC1 wt 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