[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"condition:metastatic-malignant-neoplasm-in-the-leptomeninges":3},{"name":4,"total":5,"recruiting":6,"trials":7,"biomarkers":74,"states":75},"Metastatic Malignant Neoplasm in the Leptomeninges",10,7,[8,16,22,29,35,42,48,53,60,68],{"nct_id":9,"title":10,"phases":11,"status":13,"updated_at":14,"content_modified":15},"NCT07098806","Multiple Dose Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases",[12],"Phase 1","RECRUITING","2026-08-26T02:16:45.157238Z","2026-05-05T02:43:28.363555Z",{"nct_id":17,"title":18,"phases":19,"status":13,"updated_at":20,"content_modified":21},"NCT05184816","A Study of Deferoxamine (DFO) in People With Leptomeningeal Metastasis",[12],"2026-08-26T02:17:06.985283Z","2026-05-05T02:43:28.131581Z",{"nct_id":23,"title":24,"phases":25,"status":13,"updated_at":27,"content_modified":28},"NCT06058988","Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer",[26],"Phase 2","2026-08-26T02:18:00.873391Z","2026-05-05T02:43:29.583696Z",{"nct_id":30,"title":31,"phases":32,"status":13,"updated_at":33,"content_modified":34},"NCT06518057","Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer",[26],"2026-08-26T02:17:29.353236Z","2026-05-05T02:43:28.964223Z",{"nct_id":36,"title":37,"phases":38,"status":13,"updated_at":40,"content_modified":41},"NCT06500481","Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial",[39],"Phase 3","2026-08-26T02:18:58.958025Z","2026-05-05T02:43:27.113244Z",{"nct_id":43,"title":44,"phases":45,"status":13,"updated_at":46,"content_modified":47},"NCT05746325","Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast or Lung Cancer",[],"2026-08-26T02:15:11.740957Z","2026-05-05T02:43:26.727194Z",{"nct_id":49,"title":50,"phases":51,"status":13,"updated_at":33,"content_modified":52},"NCT06417710","Standardized Clinical Assessment of Patients With Leptomeningeal Metastasis",[],"2026-05-13T02:55:06.489197Z",{"nct_id":54,"title":55,"phases":56,"status":57,"updated_at":58,"content_modified":59},"NCT07704034","Wearable-Triggered Digital Safety Net for Real-Time Monitoring & Intervention in Leptomeningeal Metastasis",[],"NOT_YET_RECRUITING","2026-08-26T02:17:01.714035Z","2026-07-19T19:36:05.084974Z",{"nct_id":61,"title":62,"phases":63,"status":65,"updated_at":66,"content_modified":67},"NCT04588545","Radiation Therapy Followed by Intrathecal Trastuzumab\u002FPertuzumab in HER2+ Breast Leptomeningeal Disease",[64],"Phase 1\u002FPhase 2","ACTIVE_NOT_RECRUITING","2026-08-03T03:02:05.931134Z","2026-05-05T02:43:29.694519Z",{"nct_id":69,"title":70,"phases":71,"status":65,"updated_at":72,"content_modified":73},"NCT06724926","Concurrent Azeliragon With Craniospinal Irradiation",[12],"2026-08-03T02:25:58.138828Z","2026-05-05T02:43:28.133911Z",[],[76,80],{"state":77,"count":78,"slug":79},"New York",5,"new-york",{"state":81,"count":82,"slug":83},"Florida",3,"florida"]