[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"condition:nicotine-dependence":3},{"name":4,"total":5,"recruiting":6,"trials":7,"biomarkers":220,"states":221},"Nicotine Dependence",34,26,[8,16,23,29,36,43,49,56,62,68,73,79,85,91,97,103,110,116,121,127,133,139,145,151,157,163,169,176,182,188,194,200,207,213],{"nct_id":9,"title":10,"phases":11,"status":13,"updated_at":14,"content_modified":15},"NCT07145866","Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)",[12],"Phase 4","RECRUITING","2026-08-26T02:16:45.157238Z","2026-07-19T19:36:05.064154Z",{"nct_id":17,"title":18,"phases":19,"status":13,"updated_at":21,"content_modified":22},"NCT07007195","Smart Olfaction App to Reduce Relapse",[20],"Early Phase 1","2026-08-26T02:19:10.436356Z","2026-07-19T19:36:05.060292Z",{"nct_id":24,"title":25,"phases":26,"status":13,"updated_at":27,"content_modified":28},"NCT06765291","Behavioral Intervention for Youth to Promote Vaping Cessation",[],"2026-08-26T02:16:31.714843Z","2026-07-19T19:36:05.038724Z",{"nct_id":30,"title":31,"phases":32,"status":13,"updated_at":34,"content_modified":35},"NCT06053567","Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity.",[33],"Phase 3","2026-08-26T02:19:08.862440Z","2026-07-05T05:32:16.739298Z",{"nct_id":37,"title":38,"phases":39,"status":13,"updated_at":41,"content_modified":42},"NCT07040566","A Trial of Varenicline for E-cigarette Cessation",[40],"Phase 2","2026-08-26T02:18:15.214990Z","2026-05-05T02:43:29.168892Z",{"nct_id":44,"title":45,"phases":46,"status":13,"updated_at":47,"content_modified":48},"NCT05276050","Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)",[],"2026-08-26T02:19:03.581490Z","2026-05-05T02:43:29.159040Z",{"nct_id":50,"title":51,"phases":52,"status":13,"updated_at":54,"content_modified":55},"NCT07487818","A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation",[53],"Phase 2\u002FPhase 3","2026-08-26T02:17:18.747857Z","2026-05-05T02:43:29.157955Z",{"nct_id":57,"title":58,"phases":59,"status":13,"updated_at":60,"content_modified":61},"NCT06688539","E-cigarette Cessation in Adults Who Co-use Cannabis",[12],"2026-08-26T02:17:53.433613Z","2026-05-05T02:43:28.856597Z",{"nct_id":63,"title":64,"phases":65,"status":13,"updated_at":66,"content_modified":67},"NCT07540780","Social Media Support Groups for Adolescent Vaping Cessation",[],"2026-08-26T02:16:01.079019Z","2026-05-05T02:43:28.125537Z",{"nct_id":69,"title":70,"phases":71,"status":13,"updated_at":14,"content_modified":72},"NCT07298902","Non-Invasive Deep Brain Neuromodulation for Smoking Cessation",[],"2026-05-05T02:43:26.679323Z",{"nct_id":74,"title":75,"phases":76,"status":13,"updated_at":77,"content_modified":78},"NCT06239350","Young Adult Tobacco\u002FNicotine and Cannabis Co-use",[],"2026-08-26T02:18:30.351130Z","2026-05-05T02:43:26.721767Z",{"nct_id":80,"title":81,"phases":82,"status":13,"updated_at":83,"content_modified":84},"NCT06909500","A Digital Intervention (ACT on Vaping App) for Vaping Cessation in Young Adult E-Cigarette Users",[],"2026-08-26T02:18:51.833592Z","2026-07-05T05:32:16.700268Z",{"nct_id":86,"title":87,"phases":88,"status":13,"updated_at":89,"content_modified":90},"NCT06506162","Abuse Liability and Appeal of Oral Nicotine Products",[],"2026-08-26T02:18:07.037408Z","2026-05-05T02:43:28.561657Z",{"nct_id":92,"title":93,"phases":94,"status":13,"updated_at":95,"content_modified":96},"NCT07698470","Brain\u002FCraving Response to Smoking Cues After Oral Nicotine Pouch Use",[],"2026-08-26T02:15:37.042762Z","2026-07-19T19:36:05.078392Z",{"nct_id":98,"title":99,"phases":100,"status":13,"updated_at":101,"content_modified":102},"NCT05630781","Orexin s Role in the Neurobiology of Substance Use Disorder",[],"2026-08-26T02:16:09.452956Z","2026-07-19T19:36:05.119450Z",{"nct_id":104,"title":105,"phases":106,"status":13,"updated_at":108,"content_modified":109},"NCT07001930","Effects of Cannabidiol on Stress and Nicotine Withdrawal",[107],"Phase 1","2026-08-26T02:15:49.658025Z","2026-05-05T02:43:28.806322Z",{"nct_id":111,"title":112,"phases":113,"status":13,"updated_at":114,"content_modified":115},"NCT05665465","Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking",[20],"2026-08-26T02:16:05.813655Z","2026-05-05T02:43:28.215198Z",{"nct_id":117,"title":118,"phases":119,"status":13,"updated_at":114,"content_modified":120},"NCT05962229","Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine",[107],"2026-05-05T02:43:28.000364Z",{"nct_id":122,"title":123,"phases":124,"status":13,"updated_at":125,"content_modified":126},"NCT05224154","Re-Connect Application for Smoking Cessation",[],"2026-08-26T02:18:04.640417Z","2026-05-05T02:43:27.625939Z",{"nct_id":128,"title":129,"phases":130,"status":13,"updated_at":131,"content_modified":132},"NCT01036581","Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging",[],"2026-08-26T02:19:07.104270Z","2026-05-05T02:43:27.516711Z",{"nct_id":134,"title":135,"phases":136,"status":13,"updated_at":137,"content_modified":138},"NCT07322432","The CONQUER Trial - Cessation Of Nicotine, QUitting With E-cigarette Reduction",[40],"2026-08-26T02:15:53.461103Z","2026-05-05T02:43:27.480355Z",{"nct_id":140,"title":141,"phases":142,"status":13,"updated_at":143,"content_modified":144},"NCT07165808","Effect of Product Characteristics on the Abuse Liability of Nicotine Pouches",[],"2026-08-26T02:16:54.044282Z","2026-05-05T02:43:26.937867Z",{"nct_id":146,"title":147,"phases":148,"status":13,"updated_at":149,"content_modified":150},"NCT06347055","NeuroControl of Nicotine Dependence",[],"2026-08-26T02:15:58.452248Z","2026-05-05T02:43:26.900899Z",{"nct_id":152,"title":153,"phases":154,"status":13,"updated_at":155,"content_modified":156},"NCT06582888","Advancing VR-based Attentional Bias as a Biomarker for Tobacco Use Disorder",[20],"2026-08-26T02:17:11.311767Z","2026-05-05T02:35:31.760955Z",{"nct_id":158,"title":159,"phases":160,"status":13,"updated_at":161,"content_modified":162},"NCT05538910","Defining Neurobiological Links Between Substance Use and Mental Illness",[],"2026-08-26T02:19:18.331180Z","2026-06-17T21:13:38.295112Z",{"nct_id":164,"title":165,"phases":166,"status":13,"updated_at":167,"content_modified":168},"NCT05587361","Beta-Adrenergic Modulation of Drug Cue Reactivity",[12],"2026-08-26T02:16:16.169331Z","2026-05-05T02:43:27.244563Z",{"nct_id":170,"title":171,"phases":172,"status":173,"updated_at":174,"content_modified":175},"NCT07460622","A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents",[],"NOT_YET_RECRUITING","2026-08-26T02:16:17.877565Z","2026-05-05T02:43:28.806887Z",{"nct_id":177,"title":178,"phases":179,"status":173,"updated_at":180,"content_modified":181},"NCT06965296","AI-Enhanced App-based Intervention for Adolescent E-cigarette Cessation",[],"2026-08-26T02:18:38.865010Z","2026-05-05T02:43:27.982792Z",{"nct_id":183,"title":184,"phases":185,"status":173,"updated_at":186,"content_modified":187},"NCT07694492","Feasibility of a Medical-Legal Partnership Model to Connect Coal Miners QuitAid",[],"2026-08-26T02:16:40.941792Z","2026-07-19T19:36:05.155233Z",{"nct_id":189,"title":190,"phases":191,"status":173,"updated_at":192,"content_modified":193},"NCT07398976","Sex Differences in E-Cigarette Perception",[],"2026-08-26T02:17:19.710918Z","2026-05-05T02:43:28.341931Z",{"nct_id":195,"title":196,"phases":197,"status":173,"updated_at":198,"content_modified":199},"NCT07661823","QAIAx (AIhealth4U) - AI Public Health Central: Microcity-A (re Quantum AI Agency Aka AI City Hall Project, UPSTO App Nos. 64\u002F074,526, 64\u002F063,557, 63\u002F903,181, 63\u002F729,428",[],"2026-08-26T02:18:26.129155Z","2026-07-05T03:45:20.367813Z",{"nct_id":201,"title":202,"phases":203,"status":204,"updated_at":205,"content_modified":206},"NCT06619964","Developing Evidence to Inform Regulatory Policy on Nicotine Content in E-Liquids",[],"ENROLLING_BY_INVITATION","2026-08-26T02:17:34.833510Z","2026-06-16T05:54:07.763205Z",{"nct_id":208,"title":209,"phases":210,"status":204,"updated_at":211,"content_modified":212},"NCT07129265","Understanding Vape Marketing Study",[],"2026-08-26T02:19:21.761002Z","2026-06-16T05:54:07.857203Z",{"nct_id":214,"title":215,"phases":216,"status":217,"updated_at":218,"content_modified":219},"NCT04176172","Optimizing Tobacco Use Treatment for PLWHA",[33],"ACTIVE_NOT_RECRUITING","2026-08-03T02:30:46.161050Z","2026-05-05T02:43:29.483589Z",[],[222,226,230,233,237,240,243],{"state":223,"count":224,"slug":225},"California",5,"california",{"state":227,"count":228,"slug":229},"Maryland",4,"maryland",{"state":231,"count":228,"slug":232},"Texas","texas",{"state":234,"count":235,"slug":236},"Connecticut",3,"connecticut",{"state":238,"count":235,"slug":239},"Massachusetts","massachusetts",{"state":241,"count":235,"slug":242},"New York","new-york",{"state":244,"count":235,"slug":245},"South Carolina","south-carolina"]