[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"condbio:solid-neoplasm:tp53-gene":3},{"condition":4,"biomarker":5,"total":6,"trials":7},"Solid Neoplasm","TP53 Gene",7,[8,16,23,29,35,41,47],{"nct_id":9,"title":10,"phases":11,"status":13,"updated_at":14,"content_modified":15},"NCT06386146","JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation",[12],"Phase 1\u002FPhase 2","RECRUITING","2026-08-26T02:19:02.550788Z","2026-07-05T05:32:16.751547Z",{"nct_id":17,"title":18,"phases":19,"status":13,"updated_at":21,"content_modified":22},"NCT07372625","A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.",[20],"Phase 1","2026-08-26T02:17:22.153941Z","2026-05-05T02:43:27.994124Z",{"nct_id":24,"title":25,"phases":26,"status":13,"updated_at":27,"content_modified":28},"NCT06667141","Phase 1 Study of ACR-2316 in Specific Advanced Solid Tumors",[20],"2026-08-26T02:18:25.327036Z","2026-05-05T02:43:27.606583Z",{"nct_id":30,"title":31,"phases":32,"status":13,"updated_at":33,"content_modified":34},"NCT07060989","A Study of Safety, Tolerability and Preliminary Efficacy of NTS071 in Subjects With Advanced Solid Tumors Harboring a TP53 Y220C Mutation",[12],"2026-08-26T02:16:27.227548Z","2026-05-05T02:35:31.649024Z",{"nct_id":36,"title":37,"phases":38,"status":13,"updated_at":39,"content_modified":40},"NCT05877599","A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation",[20],"2026-08-26T02:15:10.362237Z","2026-07-19T19:36:05.120541Z",{"nct_id":42,"title":43,"phases":44,"status":13,"updated_at":45,"content_modified":46},"NCT04585750","The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)",[12],"2026-08-26T02:17:46.653867Z","2026-05-05T02:43:27.334679Z",{"nct_id":48,"title":49,"phases":50,"status":13,"updated_at":51,"content_modified":52},"NCT06778863","A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation",[20],"2026-08-26T02:15:47.754948Z","2026-05-05T02:43:26.672516Z"]