[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"condition:total-knee-replacement":3},{"name":4,"total":5,"recruiting":6,"trials":7,"biomarkers":309,"states":310},"Total Knee Replacement",57,34,[8,16,22,28,34,40,46,53,59,66,72,78,84,91,97,103,109,115,121,127,132,138,144,150,156,162,167,173,179,185,190,196,202,208,214,221,227,233,239,245,251,257,262,268,274,280,286,293,298,303],{"nct_id":9,"title":10,"phases":11,"status":13,"updated_at":14,"content_modified":15},"NCT07485803","Methadone in the Management of Post-Operative Pain in Total Knee Replacement",[12],"Phase 4","RECRUITING","2026-08-26T02:19:08.084946Z","2026-07-05T03:45:20.251648Z",{"nct_id":17,"title":18,"phases":19,"status":13,"updated_at":20,"content_modified":21},"NCT06784882","Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty",[12],"2026-08-26T02:17:57.117858Z","2026-05-05T02:43:29.589713Z",{"nct_id":23,"title":24,"phases":25,"status":13,"updated_at":26,"content_modified":27},"NCT06617871","Mechanical Alignment vs Kalipered Kinematic Alignment Total Knee Arthroplasty",[],"2026-08-26T02:19:09.651016Z","2026-05-05T02:43:28.534149Z",{"nct_id":29,"title":30,"phases":31,"status":13,"updated_at":32,"content_modified":33},"NCT07437469","Binaural Beats for Postoperative Pain and Anxiety Reduction",[],"2026-08-26T02:19:15.498463Z","2026-05-05T02:43:28.218876Z",{"nct_id":35,"title":36,"phases":37,"status":13,"updated_at":38,"content_modified":39},"NCT06298721","Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes",[],"2026-08-26T02:18:01.700186Z","2026-05-05T02:43:27.756906Z",{"nct_id":41,"title":42,"phases":43,"status":13,"updated_at":44,"content_modified":45},"NCT06953375","Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty",[],"2026-08-26T02:17:23.750999Z","2026-05-05T02:43:27.572963Z",{"nct_id":47,"title":48,"phases":49,"status":13,"updated_at":51,"content_modified":52},"NCT06640491","Intraosseous (IO) Cefazolin and Vancomycin in Primary Total Knee Arthroplasty (TKA)",[50],"Phase 1\u002FPhase 2","2026-08-26T02:18:36.226508Z","2026-05-05T02:43:27.076525Z",{"nct_id":54,"title":55,"phases":56,"status":13,"updated_at":57,"content_modified":58},"NCT04199780","Effects of tDCS Combined With CBI on Postsurgical Pain",[],"2026-08-03T02:04:08.415522Z","2026-05-05T02:43:26.945372Z",{"nct_id":60,"title":61,"phases":62,"status":13,"updated_at":64,"content_modified":65},"NCT07015905","REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults",[63],"Phase 3","2026-08-26T02:15:27.567165Z","2026-05-05T02:35:31.930532Z",{"nct_id":67,"title":68,"phases":69,"status":13,"updated_at":70,"content_modified":71},"NCT07213778","REGN7508 Versus Acetylsalicylic Acid (ASA) 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Arthroplasty",[12],"2026-08-26T02:16:16.169331Z","2026-05-05T02:43:26.945024Z",{"nct_id":110,"title":111,"phases":112,"status":13,"updated_at":113,"content_modified":114},"NCT04295486","Optimal Dosing For Low-Dose Aspirin Chemoprophylaxis For VTE Following Total Joint Arthroplasty",[88],"2026-08-26T02:16:46.951087Z","2026-05-05T02:35:31.685375Z",{"nct_id":116,"title":117,"phases":118,"status":13,"updated_at":119,"content_modified":120},"NCT05520593","Preoperative Oral Hydration in the Ambulatory Arthroplasty Population",[],"2026-08-26T02:18:13.438956Z","2026-05-05T02:35:31.600708Z",{"nct_id":122,"title":123,"phases":124,"status":13,"updated_at":125,"content_modified":126},"NCT05381818","Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery",[],"2026-08-26T02:16:35.654046Z","2026-05-05T02:43:29.465942Z",{"nct_id":128,"title":129,"phases":130,"status":13,"updated_at":95,"content_modified":131},"NCT05658796","RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty",[],"2026-05-05T02:43:27.989438Z",{"nct_id":133,"title":134,"phases":135,"status":13,"updated_at":136,"content_modified":137},"NCT07464860","Feasibility of Breathwork Intervention With Older Adults After Knee Surgery",[],"2026-08-26T02:16:02.918558Z","2026-07-19T19:36:05.139686Z",{"nct_id":139,"title":140,"phases":141,"status":13,"updated_at":142,"content_modified":143},"NCT07647354","Mako-MORE Registry",[],"2026-08-26T02:15:30.699880Z","2026-06-16T05:54:07.904452Z",{"nct_id":145,"title":146,"phases":147,"status":13,"updated_at":148,"content_modified":149},"NCT07120191","An Open Label Data Collection Study of My Connect Post-Op, a Post-Operative Communication Tool",[],"2026-08-26T02:18:57.189473Z","2026-05-13T02:55:06.655653Z",{"nct_id":151,"title":152,"phases":153,"status":13,"updated_at":154,"content_modified":155},"NCT06379321","Evaluation of Outcomes of the Triathlon Hinge Knee (THK) System",[],"2026-08-26T02:19:16.454910Z","2026-05-13T02:55:06.488848Z",{"nct_id":157,"title":158,"phases":159,"status":13,"updated_at":160,"content_modified":161},"NCT05653102","A Post-Market Domestic (US) and International Data Collection to Assess the Truliant Knee System",[],"2026-08-26T02:16:12.203827Z","2026-05-13T02:55:06.367296Z",{"nct_id":163,"title":164,"phases":165,"status":13,"updated_at":142,"content_modified":166},"NCT05288803","Improving Rehabilitation for Veterans After Total Knee Arthroplasty Using Individualized Recovery Trajectories",[],"2026-05-13T02:55:06.298822Z",{"nct_id":168,"title":169,"phases":170,"status":13,"updated_at":171,"content_modified":172},"NCT04336579","Diaphragmatic Breathing Exercises in Total Knee Arthroplasty Patients",[],"2026-08-26T02:18:43.501109Z","2026-05-13T02:55:06.246081Z",{"nct_id":174,"title":175,"phases":176,"status":13,"updated_at":177,"content_modified":178},"NCT02692092","HealthEast Community Hip and Knee Replacement Registry",[],"2026-08-26T02:16:45.157238Z","2026-05-13T02:55:06.099195Z",{"nct_id":180,"title":181,"phases":182,"status":13,"updated_at":183,"content_modified":184},"NCT07672301","Total Intravenous Anesthesia vs Spinal Anesthesia in Patients Undergoing Unilateral Primary Total Knee Arthroplasty",[50],"2026-08-26T02:18:31.944757Z","2026-07-05T03:45:20.372071Z",{"nct_id":186,"title":187,"phases":188,"status":13,"updated_at":113,"content_modified":189},"NCT05858086","Is Physical Therapy Clearance Before Arthroplasty Home Discharge Necessary?",[],"2026-05-05T02:43:29.169656Z",{"nct_id":191,"title":192,"phases":193,"status":13,"updated_at":194,"content_modified":195},"NCT06733597","Femoral BMD Change Following Cemented or Cementless Total Knee Arthroplasty",[],"2026-08-26T02:16:58.658552Z","2026-05-05T02:43:29.165715Z",{"nct_id":197,"title":198,"phases":199,"status":13,"updated_at":200,"content_modified":201},"NCT06080152","Observation of Wheeled Device Use After TKA",[],"2026-08-26T02:16:52.995882Z","2026-05-05T02:43:29.134887Z",{"nct_id":203,"title":204,"phases":205,"status":13,"updated_at":206,"content_modified":207},"NCT04924205","A Comparison Of Primary TKA Rehabilitation Using A Smart Orthotic Versus Outpatient Physical Therapy",[],"2026-08-26T02:17:18.747857Z","2026-05-05T02:43:27.975059Z",{"nct_id":209,"title":210,"phases":211,"status":13,"updated_at":212,"content_modified":213},"NCT07371390","Minimal Sedation During Knee Replacement Surgery",[],"2026-08-26T02:17:16.126291Z","2026-05-05T02:43:27.603270Z",{"nct_id":215,"title":216,"phases":217,"status":218,"updated_at":219,"content_modified":220},"NCT07439666","NEUROCUPLE™ as an Opioid Alternative Following Total Knee Arthroplasty",[],"NOT_YET_RECRUITING","2026-08-26T02:17:33.002248Z","2026-05-05T02:43:28.962046Z",{"nct_id":222,"title":223,"phases":224,"status":218,"updated_at":225,"content_modified":226},"NCT07097493","Liposomal Bupivacaine vs Perineural Adjuvants in Adductor Canalf and iPACK Blocks in Total Knee Arthroplasty",[12],"2026-08-26T02:18:48.678868Z","2026-05-05T02:43:28.957600Z",{"nct_id":228,"title":229,"phases":230,"status":218,"updated_at":231,"content_modified":232},"NCT06333938","Veterans Enhanced Recovery Using Integrative Treatments Around Surgery",[12],"2026-08-26T02:16:48.735701Z","2026-05-05T02:43:28.957178Z",{"nct_id":234,"title":235,"phases":236,"status":218,"updated_at":237,"content_modified":238},"NCT07348835","Using a Smart Implantable Device to Compare Early Recovery in Two Different Knee Arthroplasty Approaches",[],"2026-08-26T02:19:20.945539Z","2026-05-05T02:43:28.873666Z",{"nct_id":240,"title":241,"phases":242,"status":218,"updated_at":243,"content_modified":244},"NCT07219329","The Feasibility of a Nurse-Initiated Weighted Blanket in Orthopedic Surgical Patients Undergoing Total Knee Arthroplasty",[],"2026-08-26T02:15:24.145250Z","2026-05-05T02:43:28.731209Z",{"nct_id":246,"title":247,"phases":248,"status":218,"updated_at":249,"content_modified":250},"NCT06654661","Utilization of a 3D Printed Mechanical Balancer During Total Knee Arthroplasty (TKA)",[],"2026-08-26T02:17:14.343713Z","2026-05-05T02:43:26.688900Z",{"nct_id":252,"title":253,"phases":254,"status":218,"updated_at":255,"content_modified":256},"NCT07639723","Aprepitant to Improve Same Day Discharge for TKA",[12],"2026-08-26T02:17:53.433613Z","2026-06-14T18:39:22.258211Z",{"nct_id":258,"title":259,"phases":260,"status":218,"updated_at":237,"content_modified":261},"NCT07633418","IO Vancomycin Administration in TKA",[12],"2026-06-14T18:39:22.250367Z",{"nct_id":263,"title":264,"phases":265,"status":218,"updated_at":266,"content_modified":267},"NCT07598734","Doxepin Alone or Combined With Ramelteon Versus Placebo for Improving Sleep Quality After Primary Total Knee Arthroplasty",[12],"2026-08-26T02:15:22.311223Z","2026-05-29T15:36:40.207490Z",{"nct_id":269,"title":270,"phases":271,"status":218,"updated_at":272,"content_modified":273},"NCT07598539","Knee Replacement Rehabilitation Care Pathways",[],"2026-08-26T02:15:09.079045Z","2026-05-29T15:36:40.207367Z",{"nct_id":275,"title":276,"phases":277,"status":218,"updated_at":278,"content_modified":279},"NCT07494032","Extended Oral Tranexamic Acid After Primary Total Knee Arthroplasty",[],"2026-08-26T02:19:26.493949Z","2026-05-05T02:43:28.479302Z",{"nct_id":281,"title":282,"phases":283,"status":218,"updated_at":284,"content_modified":285},"NCT05592847","A Study of the Effect of a Nurse Navigator Program on High Risk Patients",[],"2026-08-26T02:16:06.684983Z","2026-05-05T02:43:29.228993Z",{"nct_id":287,"title":288,"phases":289,"status":290,"updated_at":291,"content_modified":292},"NCT06447922","Metal Ion Concentrations After Total Knee Arthroplasty",[],"ENROLLING_BY_INVITATION","2026-08-26T02:17:52.450442Z","2026-07-19T19:36:05.132576Z",{"nct_id":294,"title":295,"phases":296,"status":290,"updated_at":272,"content_modified":297},"NCT05159739","Genetic Susceptibility to Periprosthetic Joint Infections",[],"2026-06-16T05:54:07.978043Z",{"nct_id":299,"title":300,"phases":301,"status":290,"updated_at":26,"content_modified":302},"NCT05112302","A Study to Evaluate Virtual Reality As Adjunct to Anesthesia During Orthopedic Surgery",[],"2026-06-16T05:54:07.976302Z",{"nct_id":304,"title":305,"phases":306,"status":290,"updated_at":307,"content_modified":308},"NCT07584915","Pilot Study on EXPAREL as an Intra-articular Posteromedial Surgeon Administered (IPSA) Block vs. Local Infiltration Analgesia in Knee Replacement Surgery",[12],"2026-08-26T02:16:04.914942Z","2026-06-16T05:54:07.899547Z",[],[311,315,319,322,326,329,333,336,340,343,347,351,354],{"state":312,"count":313,"slug":314},"Florida",12,"florida",{"state":316,"count":317,"slug":318},"California",8,"california",{"state":320,"count":317,"slug":321},"New York","new-york",{"state":323,"count":324,"slug":325},"Colorado",7,"colorado",{"state":327,"count":324,"slug":328},"Ohio","ohio",{"state":330,"count":331,"slug":332},"Illinois",6,"illinois",{"state":334,"count":331,"slug":335},"Pennsylvania","pennsylvania",{"state":337,"count":338,"slug":339},"Minnesota",5,"minnesota",{"state":341,"count":338,"slug":342},"North Carolina","north-carolina",{"state":344,"count":345,"slug":346},"Utah",4,"utah",{"state":348,"count":349,"slug":350},"Maryland",3,"maryland",{"state":352,"count":349,"slug":353},"South Carolina","south-carolina",{"state":355,"count":349,"slug":356},"Texas","texas"]