[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT00439049":3,"trial-entities:NCT00439049":120,"trial-summary:NCT00439049":125},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":24,"study_type":27,"primary_purpose":28,"phases":29,"enrollment_info":30,"interventions":33,"primary_outcomes":60,"secondary_outcomes":64,"sex":67,"minimum_age":68,"maximum_age":69,"healthy_volunteers":70,"eligibility_criteria":71,"std_ages":84,"locations":86,"central_contacts":106,"overall_officials":111,"references":118,"see_also_links":119},"NCT00439049","NIDA-09262-13","Substance Abuse Pre-Treatment Screening Study","General Evaluation of Eligibility for Substance Abuse\u002FDependence Research","UNKNOWN","2026-06","2023-12","2023-12-20","2005-10","The University of Texas Health Science Center, Houston","OTHER",true,"The overarching goal of this project is to have a consolidated consent and evaluation procedure that will lead potential subjects to the most appropriate clinical trial or human laboratory study (and its consent process) for their presenting concerns or interests. A second purpose is to have a consolidated intake data base on which secondary analyses can be conducted.","Approximately 1500 candidates per year will respond to advertisements and will complete preliminary telephone screening without identifiers. Appropriate candidates will be given appointment times and on arrival will undergo the consent process for evaluation. A complete medical, social, psychiatric, and drug use history will be obtained. Subjects fulfilling general health inclusion requirements will then be offered an appropriate study for which the specific consent will be obtained. The evaluation period will be no more than one day with all results evaluated within the two following days. Acceptable candidates will then be invited to complete the study specific consent.",[19,20,21,22,23],"Cocaine Abuse","Cocaine Dependence","Opiate Dependence","Alcohol Dependence","Substance Abuse",[23,25,26],"Treatment","Eligibility","OBSERVATIONAL",null,[],{"count":31,"type":32},7500,"ESTIMATED",[34,42,48,54],{"type":35,"name":36,"description":37,"armGroupLabels":38,"otherNames":40},"DRUG","modafinil","400 mg daily",[39],"A",[41],"Provigil",{"type":35,"name":43,"description":44,"armGroupLabels":45,"otherNames":46},"d-amphetamine","60mg daily",[39],[47],"Dexedrine",{"type":35,"name":49,"description":50,"armGroupLabels":51,"otherNames":52},"L-Dopa","800\u002F200mg daily",[39],[53],"Sinemet",{"type":35,"name":55,"description":56,"armGroupLabels":57,"otherNames":58},"Naltrexone","50mg daily",[39],[59],"Revia",[61],{"measure":62,"timeFrame":63},"Urine Toxicology","6 weeks to 24 weeks",[65],{"measure":66,"timeFrame":63},"Demographics","ALL","18 Years","60 Years",false,{"inclusion":72,"exclusion":77,"raw_text":83},[73,74,75,76],"Willing and able to participate in 3- to 6-month treatment program.","At least 18 years of age.","Seeking treatment for substances of abuse including (cocaine, opiates, and alcohol).","Generally physically healthy.",[78,79,80,81,82],"Pregnant or breastfeeding.","Mandated by the courts\u002Fparole officers to attend treatment.","Not seeking treatment for substances of abuse.","Plans to move from the Houston area within the 3- to 6-month treatment period.","Seeking treatment for a substance for which the Treatment Research Clinic (TRC) has no current trial.","Inclusion Criteria:\n\n* Willing and able to participate in 3- to 6-month treatment program.\n* At least 18 years of age.\n* Seeking treatment for substances of abuse including (cocaine, opiates, and alcohol).\n* Generally physically healthy.\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding.\n* Mandated by the courts\u002Fparole officers to attend treatment.\n* Not seeking treatment for substances of abuse.\n* Plans to move from the Houston area within the 3- to 6-month treatment period.\n* Seeking treatment for a substance for which the Treatment Research Clinic (TRC) has no current trial.",[85],"ADULT",[87],{"facility":88,"status":89,"city":90,"state":91,"zip":92,"country":93,"contacts":94,"geoPoint":103},"University of Texas Medical School- Houston, Dept. of Psychiatry Mental Sciences Institute","RECRUITING","Houston","Texas","77054","United States",[95,100],{"name":96,"role":97,"phone":98,"email":99},"Rolanda Johnson, MA","CONTACT","713-486-2823","Rolanda.Johnson@uth.tmc.edu",{"name":101,"role":102},"Joy M Schmitz, Ph.D.","PRINCIPAL_INVESTIGATOR",{"lat":104,"lon":105},29.76328,-95.36327,[107],{"name":108,"role":97,"phone":109,"email":110},"Jessica Vincent, BS","713-486-2803","Jessica.N.Vincent@uth.tmc.edu",[112,114,116],{"name":113,"affiliation":13,"role":102},"Joy M. Schmitz, PhD",{"name":115,"affiliation":13,"role":102},"Frederick G Moeller, MD",{"name":117,"affiliation":13,"role":102},"Angela L Stotts, PhD",[],[],{"nct_id":4,"conditions":121,"biomarkers":124},[22,20,122,123,23],"Harmful pattern of use of cocaine","Opioid-Related Disorders",[],{"nct_id":4,"found":15,"summary":126,"prompt_version":135},{"design":127,"status":128,"heading":6,"summary":129,"follow_up":130,"word_count":131,"commitments":132,"compensation":133,"drugs_mentioned":134},"This is an observational study planning to enroll 7500 participants. It's designed to screen potential participants for other treatment studies.","completed","This study is an observational study for people seeking treatment for substance abuse, including cocaine, opiates, and alcohol. It aims to connect you with the most suitable clinical trial or study for your needs. While this study itself doesn't test specific treatments, the overall project involves drugs like modafinil, d-amphetamine, L-Dopa, and Naltrexone in other related trials. To join, you must be 18 to 60 years old, seeking treatment, and generally healthy. Success in this screening study means being directed to an appropriate treatment study. The current status of this study is unclear.","Not specified.",93,"You would undergo a one-day evaluation including a medical, social, psychiatric, and drug use history. This evaluation helps determine if you qualify for other treatment studies.","Not stated in the trial record.",[36,43,49,55],"v2"]