[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT00921986":3,"trial-entities:NCT00921986":90,"trial-summary:NCT00921986":105},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":20,"study_type":35,"primary_purpose":36,"phases":37,"enrollment_info":38,"interventions":41,"primary_outcomes":42,"secondary_outcomes":47,"sex":48,"minimum_age":49,"maximum_age":36,"healthy_volunteers":15,"eligibility_criteria":50,"std_ages":57,"locations":60,"central_contacts":81,"overall_officials":86,"references":88,"see_also_links":89},"NCT00921986","09-176","Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic","Cleveland Clinic Arrhythmia Biospecimen Repository (Cleveland Clinic Arrhythmia BioBank)","RECRUITING","2035-12","2025-08","2025-09-10","2009-03","The Cleveland Clinic","OTHER",true,"Biorepository of blood and or tissue samples from patients presenting with cardiac arrhythmia syndromes.","The long-term objective of this research is to find genes and biologic pathways causing arrhythmia syndromes and other diseases or conditions. In order to achieve this objective the investigators will collect comprehensive phenotypic data and corresponding blood and\u002For tissue samples into a biorepository registry of patients, presenting for cardiac arrhythmia evaluation and\u002For treatment, and control subjects without arrhythmias. This biorepository will be composed of two parts: 1) An Arrhythmia Biorepository of blood and tissue from patients undergoing arrhythmia procedures, cardiac surgery, or inpatient or outpatient evaluations for arrhythmias, and 2) A Collaborative Sample Biorepository for de-identified samples and data from outside institutions and clinical trials.",[19],"Arrhythmias, Cardiac",[21,22,23,24,25,26,27,28,29,30,31,32,33,34],"genetics","biorepository","cardiac death","atrial fibrillation","ventricular fibrillation","ventricular tachycardia","supraventricular tachycardias","premature ventricular complexes","premature atrial complexes","atrioventricular and intraventricular blocks","sinus node dysfunction","syncope","vasovagal reactivity","postural orthostatic tachycardia syndrome","OBSERVATIONAL",null,[],{"count":39,"type":40},2000,"ESTIMATED",[],[43],{"measure":44,"description":45,"timeFrame":46},"Genetic variants associated with arrhythmias","Genome-wide association study of arrhythmias","Baseline",[],"ALL","18 Years",{"inclusion":51,"exclusion":54,"raw_text":56},[52,53],"Male or female at least 18 years old","Subjects with a history of or current cardiac arrhythmia, family members of subjects with cardiac arrhythmias, or no cardiac arrhythmia if a Control Subject.",[55],"Subjects previously enrolled in the Arrhythmia BioBank","Inclusion Criteria:\n\n* Male or female at least 18 years old\n* Subjects with a history of or current cardiac arrhythmia, family members of subjects with cardiac arrhythmias, or no cardiac arrhythmia if a Control Subject.\n\nExclusion Criteria:\n\n* Subjects previously enrolled in the Arrhythmia BioBank",[58,59],"ADULT","OLDER_ADULT",[61],{"facility":62,"status":8,"city":63,"state":64,"zip":65,"country":66,"contacts":67,"geoPoint":78},"Cleveland Clinic Foundation","Cleveland","Ohio","44195","United States",[68,71,74,76],{"name":69,"role":70},"Mina K. Chung, MD","PRINCIPAL_INVESTIGATOR",{"name":72,"role":73},"David R. Van Wagoner, Ph.D.","SUB_INVESTIGATOR",{"name":75,"role":73},"Jonathan D. Smith, Ph.D.",{"name":77,"role":73},"John Barnard, Ph.D.",{"lat":79,"lon":80},41.4995,-81.69541,[82],{"name":69,"role":83,"phone":84,"email":85},"CONTACT","216.444.2290","chungm@ccf.org",[87],{"name":69,"affiliation":13,"role":70},[],[],{"nct_id":4,"conditions":91,"biomarkers":104},[92,93,94,95,96,97,98,99,100,101,102,103],"Arrhythmia","Atrial Fibrillation","Atrial Premature Complex by ECG Finding","Atrioventricular Block by ECG Finding","Intraventricular Block","Postural Orthostatic Tachycardia Syndrome","Sinus Node Dysfunction","Supraventricular Tachycardia","Syncope","Ventricular Fibrillation","Ventricular premature complex","Ventricular Tachycardia",[],{"nct_id":4,"found":15,"summary":106,"prompt_version":116},{"design":107,"status":108,"heading":109,"summary":110,"follow_up":111,"word_count":112,"commitments":113,"compensation":114,"drugs_mentioned":115},"This is an observational study aiming to enroll 2000 participants. It involves collecting samples and health information to understand heart rhythm problems.","completed","Biospecimen Repository for Cardiac Arrhythmias","This study is creating a collection of blood and\u002For tissue samples from people with heart rhythm problems (cardiac arrhythmias) and healthy volunteers. Researchers want to find genes and biological processes that cause arrhythmias and other conditions. They will collect detailed health information and samples from patients undergoing arrhythmia procedures or evaluations, and from control subjects without arrhythmias. The main goal is to identify genetic differences linked to arrhythmias. You can join if you are at least 18 years old and have a history of or current cardiac arrhythmia, are a family member of someone with an arrhythmia, or are a healthy control. You cannot join if you have already participated in the Arrhythmia BioBank.","Genetic variants associated with arrhythmias are measured at Baseline, which is the start of the study.",114,"Not specified in the trial record.","Not stated in the trial record.",[],"v2"]