[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT01219361":3,"trial-entities:NCT01219361":68,"trial-summary:NCT01219361":72},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":22,"study_type":24,"primary_purpose":25,"phases":26,"enrollment_info":27,"interventions":30,"primary_outcomes":31,"secondary_outcomes":36,"sex":40,"minimum_age":41,"maximum_age":42,"healthy_volunteers":43,"eligibility_criteria":44,"std_ages":48,"locations":51,"central_contacts":61,"overall_officials":62,"references":66,"see_also_links":67},"NCT01219361","RMA-00-05","Evaluation of Donated Human Embryos Following in Vitro Fertilization","Evaluation of Donated Human Embryos for Study of Normal and Abnormal Differentiation and Development Following in Vitro Fertilization.","ENROLLING_BY_INVITATION","2026-12","2025-02","2025-02-07","2005-07","Reproductive Medicine Associates of New Jersey","OTHER",false,"Couples who have created excess embryos while undergoing IVF procedures, and who do not wish to transfer those embryos or donate them to another couple may donate the extra embryos to research. The embryos are then used to develop improved laboratory techniques and conditions as well as testing the proficiency of laboratory staff.","Undergoing IVF treatment often results in the production of more embryos than can safely be transferred at one time. These extra embryos are often cryopreserved for future use. In the event that a couple decides that they do not want to proceed with using cryopreserved embryos, these embryos can be discarded, donated to another couple, or donated to research.\n\nEmbryos that are donated to research are used to identify a group of parameters that have significant predictive value for assisted reproductive technology outcomes. We hope to develop future laboratory techniques as we gain a better knowledge of gamete development, fertilization and implantation. We will test, standardize and implement better methods for freezing embryos prior to employing these techniques in a clinical setting. We hope to develop new methods to optimize the determination of genes and chromosomes in embryos. We will test the proficiency of laboratory staff on techniques and\u002For procedures done in the IVF laboratory. This study WILL NOT:create embryos for research, transfer embryos to an individual, develop cell lines or clones.",[19,20,21],"Validation of Laboratory Techniques","Validation of Laboratory Methods","Assessment of Laboratory Staff Proficiency",[23],"Donated embryos","OBSERVATIONAL",null,[],{"count":28,"type":29},5000,"ESTIMATED",[],[32],{"measure":33,"description":34,"timeFrame":35},"Freezing methods for embryos","To test, standardize and implement better methods for the freezing of embryos prior to these techniques being implemented in the clinical setting.","duration of the study",[37],{"measure":38,"description":39,"timeFrame":35},"Development of New Methods","The development of new methods to optimize the determination of genes and chromosomes in embryos","ALL","18 Years","65 Years",true,{"inclusion":45,"exclusion":46,"raw_text":47},[],[],"Inclusion Criteria:\n\nnone\n\nExclusion Criteria:\n\nnone",[49,50],"ADULT","OLDER_ADULT",[52],{"facility":53,"city":54,"state":55,"zip":56,"country":57,"geoPoint":58},"Reproductive Medicine Assoicates of New Jersey","Basking Ridge","New Jersey","07920","United States",{"lat":59,"lon":60},40.70621,-74.54932,[],[63],{"name":64,"affiliation":13,"role":65},"Thomas Molinaro, MD, MSCE","PRINCIPAL_INVESTIGATOR",[],[],{"nct_id":4,"conditions":69,"biomarkers":71},[70],"Donated Embryos",[],{"nct_id":4,"found":15,"summary":25,"prompt_version":25}]