[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT03492372":3,"trial-entities:NCT03492372":67,"trial-summary:NCT03492372":21},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":16,"conditions":17,"keywords":19,"study_type":20,"primary_purpose":21,"phases":22,"enrollment_info":23,"interventions":26,"primary_outcomes":32,"secondary_outcomes":37,"sex":38,"minimum_age":39,"maximum_age":40,"healthy_volunteers":14,"eligibility_criteria":41,"std_ages":47,"locations":51,"central_contacts":60,"overall_officials":61,"references":65,"see_also_links":66},"NCT03492372","14-008177","Molecular Characterization of Spinal Tissue","ENROLLING_BY_INVITATION","2026-07","2025-09","2025-09-19","2015-03-31","Mayo Clinic","OTHER",false,"The researchers are trying to identify molecular mechanisms that control spine deformity and degenerative changes that can be used for therapeutic strategies.","Discarded surgical material from spinal procedures is collected. RNA analysis and other tests on the tissue is performed to determine markers of pathologic disease and to develop pharmacologic treatment strategies for pediatric spinal disorders.",[18],"Spinal Diseases",[],"OBSERVATIONAL",null,[],{"count":24,"type":25},300,"ESTIMATED",[27],{"type":13,"name":28,"description":29,"armGroupLabels":30},"Waste tissues are collected at the time of spinal surgery.","This is a single visit study. Waste tissues are collected at the time of spinal surgery.",[31],"Spine patients",[33],{"measure":34,"description":35,"timeFrame":36},"RNA expression","Measure RNA levels in spinal tissues samples (ng\u002FmL)","Baseline",[],"ALL","1 Year","80 Years",{"inclusion":42,"exclusion":44,"raw_text":46},[43],"Children and adults undergoing surgical procedures where spinal tissues are removed as a normal part of their procedure. Material from adults may be collected as a control group.",[45],"Surgeries where spinal tissues are not being removed.","Inclusion Criteria:\n\n* Children and adults undergoing surgical procedures where spinal tissues are removed as a normal part of their procedure. Material from adults may be collected as a control group.\n\nExclusion Criteria:\n\n* Surgeries where spinal tissues are not being removed.",[48,49,50],"CHILD","ADULT","OLDER_ADULT",[52],{"facility":12,"city":53,"state":54,"zip":55,"country":56,"geoPoint":57},"Rochester","Minnesota","55905","United States",{"lat":58,"lon":59},44.02163,-92.4699,[],[62],{"name":63,"affiliation":12,"role":64},"A.Noelle Larson, MD","PRINCIPAL_INVESTIGATOR",[],[],{"nct_id":4,"conditions":68,"biomarkers":70},[69],"Disorder of vertebral column",[]]