[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT03501589":3,"trial-entities:NCT03501589":63,"trial-summary:NCT03501589":67},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":14,"conditions":16,"keywords":18,"study_type":19,"primary_purpose":14,"phases":20,"enrollment_info":21,"interventions":24,"primary_outcomes":25,"secondary_outcomes":30,"sex":31,"minimum_age":14,"maximum_age":14,"healthy_volunteers":32,"eligibility_criteria":33,"std_ages":39,"locations":43,"central_contacts":53,"overall_officials":54,"references":58,"see_also_links":59},"NCT03501589","13-005403","Molecular Modulation of the Growth Plate","ENROLLING_BY_INVITATION","2026-10","2025-12","2025-12-18","2013-10-31","Mayo Clinic","OTHER",null,"The researchers are trying to identify molecular mechanisms that control growth plate mediated limb growth and identify agents that can be used to enhance or slow growth.",[17],"Growth Plate Injury",[],"OBSERVATIONAL",[],{"count":22,"type":23},100,"ESTIMATED",[],[26],{"measure":27,"description":28,"timeFrame":29},"RNA expression","Measure RNA levels in growth plate tissue samples (ng\u002FmL)","End of Study (1\u002F2019",[],"ALL",false,{"inclusion":34,"exclusion":36,"raw_text":38},[35],"Skeletally immature children\u002Fadults undergoing surgical procedures where growth plate cartilage is removed as a normal part of their procedure; or patients undergoing surgical procedures where bone is removed as a normal part of their procedure.",[37],"Skeletally mature children\u002Fadults","Inclusion Criteria:\n\n* Skeletally immature children\u002Fadults undergoing surgical procedures where growth plate cartilage is removed as a normal part of their procedure; or patients undergoing surgical procedures where bone is removed as a normal part of their procedure.\n\nExclusion Criteria:\n\n* Skeletally mature children\u002Fadults",[40,41,42],"CHILD","ADULT","OLDER_ADULT",[44],{"facility":45,"city":46,"state":47,"zip":48,"country":49,"geoPoint":50},"Mayo Clinic'","Rochester","Minnesota","55905","United States",{"lat":51,"lon":52},44.02163,-92.4699,[],[55],{"name":56,"affiliation":12,"role":57},"A. Noelle Larson, M.D.","PRINCIPAL_INVESTIGATOR",[],[60],{"label":61,"url":62},"Mayo Clinic Clinical Trials","https:\u002F\u002Fwww.mayo.edu\u002Fresearch\u002Fclinical-trials",{"nct_id":4,"conditions":64,"biomarkers":66},[65],"Salter-Harris Fractures",[],{"nct_id":4,"found":32,"summary":14,"prompt_version":14}]