[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT03992625":3,"trial-entities:NCT03992625":78,"trial-summary:NCT03992625":81},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":22,"study_type":24,"primary_purpose":17,"phases":25,"enrollment_info":26,"interventions":29,"primary_outcomes":34,"secondary_outcomes":39,"sex":40,"minimum_age":17,"maximum_age":17,"healthy_volunteers":15,"eligibility_criteria":41,"std_ages":50,"locations":54,"central_contacts":70,"overall_officials":73,"references":76,"see_also_links":77},"NCT03992625","201101744","Clinical Outcomes for Deep Brain Stimulation","Clinical Outcomes for Deep Brain Stimulation for Parkinson Disease, Tremor, and Dystonia","RECRUITING","2030-01-01","2019-06","2019-06-20","2011-01-03","Washington University School of Medicine","OTHER",false,"The object of this study is to longitudinally collect clinical outcomes of patients receiving deep brain stimulation for movement disorders with the objective of making retrospective comparisons and tracking of risks, benefits, and complications.",null,[19,20,21],"Parkinson Disease","Essential Tremor","Dystonia",[23],"Deep brain stimulation","OBSERVATIONAL",[],{"count":27,"type":28},1000,"ESTIMATED",[30],{"type":31,"name":32,"description":33},"DEVICE","Deep Brain Stimulation","High frequency electrical stimulation of deep brain nuclei for the treatment of movement disorders",[35],{"measure":36,"description":37,"timeFrame":38},"UPDRS","United Parkinson's Disease Rating Scale (global assessment of motor, non-motor, and quality of life associated with symptoms of Parkinson disease). Total scores range from 0-199. Particular emphasis is paid to subsection 3 (motor), where scores range from 0-56.","Change in UPDRS at 1 year after DBS (from preoperative baseline).",[],"ALL",{"inclusion":42,"exclusion":46,"raw_text":49},[43,44,45],"Levodopa responsive Parkinson disease OR","Medically refractory Essential Tremor OR","Medically refractory Dystonia",[47,48],"Dementia (Mattis Dementia Rating Scale \\\u003C130)","Structural abnormalities precluding intracranial surgery","Inclusion Criteria:\n\n* Levodopa responsive Parkinson disease OR\n* Medically refractory Essential Tremor OR\n* Medically refractory Dystonia\n\nExclusion Criteria:\n\n* Dementia (Mattis Dementia Rating Scale \\\u003C130)\n* Structural abnormalities precluding intracranial surgery",[51,52,53],"CHILD","ADULT","OLDER_ADULT",[55],{"facility":56,"status":8,"city":57,"state":58,"zip":59,"country":60,"contacts":61,"geoPoint":67},"Washington University in St Louis","St Louis","Missouri","63110","United States",[62],{"name":63,"role":64,"phone":65,"email":66},"Mwiza Ushe, M.D.","CONTACT","314-362-5262","ushem@wustl.edu",{"lat":68,"lon":69},38.62727,-90.19789,[71],{"name":63,"role":64,"phone":72,"email":66},"3143625262",[74],{"name":63,"affiliation":13,"role":75},"PRINCIPAL_INVESTIGATOR",[],[],{"nct_id":4,"conditions":79,"biomarkers":80},[21,20,19],[],{"nct_id":4,"found":82,"summary":83,"prompt_version":93},true,{"design":84,"status":85,"heading":86,"summary":87,"follow_up":88,"word_count":89,"commitments":90,"compensation":91,"drugs_mentioned":92},"This is an observational study that plans to include 1000 participants. It is not a randomized trial.","completed","Clinical Outcomes for Deep Brain Stimulation in Movement Disorders","This study is looking at the real-world results of Deep Brain Stimulation (DBS) for people with Parkinson's Disease, Essential Tremor, or Dystonia. DBS is a treatment that uses high-frequency electrical stimulation to help control movement disorders. You might be able to join if you have Parkinson's that responds to levodopa, or if your Essential Tremor or Dystonia hasn't improved with other treatments. The study aims to understand how well DBS works over time, including its benefits, risks, and any problems. Researchers will measure changes in your symptoms using a tool called UPDRS one year after your DBS surgery to see how successful the treatment has been. This is an observational study, meaning researchers will collect information from people already receiving DBS.","Participants' symptoms will be measured one year after Deep Brain Stimulation surgery.",121,"Not specified in the trial record.","Not stated in the trial record.",[32],"v2"]