[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT04489238":3,"trial-entities:NCT04489238":153,"trial-summary:NCT04489238":157},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":15,"conditions":17,"keywords":20,"study_type":23,"primary_purpose":15,"phases":24,"enrollment_info":25,"interventions":28,"primary_outcomes":37,"secondary_outcomes":42,"sex":43,"minimum_age":44,"maximum_age":15,"healthy_volunteers":45,"eligibility_criteria":46,"std_ages":61,"locations":64,"central_contacts":139,"overall_officials":146,"references":149,"see_also_links":150},"NCT04489238","20-315","Collection of Information to Better Understand Young Onset Colorectal Cancer","Young Onset Gastrointestinal Cancer Prospective Registry","RECRUITING","2026-07-22","2026-02","2026-02-06","2020-07-22","Memorial Sloan Kettering Cancer Center","OTHER",null,"The purpose of this registry study is to create a database-a collection of information-for better understanding young onset colorectal cancer. Colorectal cancer patients are considered to have young onset colorectal cancer if they are diagnosed with their cancer before the age of 50. Researchers will use the information from this database to learn more about how young onset colorectal cancer may be similar to or different from colorectal cancer that is diagnosed later in life. Researchers will also use information from the database for current and future research on young onset colorectal cancer.",[18,19],"Colorectal Cancer","Colorectal Carcinoma",[21,22,5,13],"young onset colorectal cancer","colorectal registry","OBSERVATIONAL",[],{"count":26,"type":27},1366,"ESTIMATED",[29],{"type":14,"name":30,"description":31,"armGroupLabels":32,"otherNames":35},"Risk Factor Questionnaire","Participants, both cases and controls, will complete the CYOC risk factor questionnaire, preferably at the time of first visit",[33,34],"Average onset Colorectal Cancer Participants","Young onset Colorectal Cancer Participants",[36],"CYOC Risk Factor Questionnaire",[38],{"measure":39,"description":40,"timeFrame":41},"Establish a prospective database of patients with Young Onset Colorectal Cancer","from diagnosis through survivorship","1 year",[],"ALL","18 Years",false,{"inclusion":47,"exclusion":59,"raw_text":60},[48,49,50,51,52,53,54,55,56,57,58],"Histological or cytological diagnosis of gastrointestinal cancer","18 - 49 years old at time of consent","No Known hereditary CRC or other cancer predisposition syndrome (stool collection cohort only)","No history of inflammatory bowel disease (stool collection cohort only)","No prior diagnosis of gastrointestinal cancer (stool collection cohort only)","Histological or cytological diagnosis of colorectal adenocarcinoma","No previous treatment for CRC (including surgery, chemotherapy, immunotherapy or radiation)","Age 50 or older at time of consent","No Known hereditary CRC or other cancer predisposition syndrome","No history of inflammatory bowel disease","No prior diagnosis of CRC",[],"Inclusion Criteria:\n\nParticipant Inclusion Criteria for database and questionnaire (YOGI)\n\n* Histological or cytological diagnosis of gastrointestinal cancer\n* 18 - 49 years old at time of consent\n* No Known hereditary CRC or other cancer predisposition syndrome (stool collection cohort only)\n* No history of inflammatory bowel disease (stool collection cohort only)\n* No prior diagnosis of gastrointestinal cancer (stool collection cohort only)\n\nParticipant Inclusion Criteria for database and questionnaire (Controls)\n\n* Histological or cytological diagnosis of colorectal adenocarcinoma\n* No previous treatment for CRC (including surgery, chemotherapy, immunotherapy or radiation)\n* Age 50 or older at time of consent\n* No Known hereditary CRC or other cancer predisposition syndrome\n* No history of inflammatory bowel disease\n* No prior diagnosis of CRC",[62,63],"ADULT","OLDER_ADULT",[65,79,88,97,107,117,125,130],{"facility":66,"status":8,"city":67,"state":68,"zip":69,"country":70,"contacts":71,"geoPoint":76},"Memorial Sloan Kettering Basking Ridge (All Protocol Activities)","Basking Ridge","New Jersey","07920","United States",[72],{"name":73,"role":74,"phone":75},"Andrea Cercek, MD","CONTACT","646-888-4189",{"lat":77,"lon":78},40.70621,-74.54932,{"facility":80,"status":8,"city":81,"state":68,"zip":82,"country":70,"contacts":83,"geoPoint":85},"Memorial Sloan Kettering Monmouth","Middletown","07748",[84],{"name":73,"role":74,"phone":75},{"lat":86,"lon":87},40.39428,-74.11709,{"facility":89,"status":8,"city":90,"state":68,"zip":91,"country":70,"contacts":92,"geoPoint":94},"Memorial Sloan Kettering Bergen","Montvale","07645",[93],{"name":73,"role":74,"phone":75},{"lat":95,"lon":96},41.04676,-74.02292,{"facility":98,"status":8,"city":99,"state":100,"zip":101,"country":70,"contacts":102,"geoPoint":104},"Memorial Sloan Kettering Cancer Center @ Commack","Commack","New York","11725",[103],{"name":73,"role":74,"phone":75},{"lat":105,"lon":106},40.84288,-73.29289,{"facility":108,"status":8,"city":109,"state":100,"zip":110,"country":70,"contacts":111,"geoPoint":114},"Memorial Sloan Kettering Westchester","Harrison","10604",[112],{"name":113,"role":74,"phone":75},"Andrew Cercek, MD",{"lat":115,"lon":116},40.96899,-73.71263,{"facility":118,"status":8,"city":100,"state":100,"zip":119,"country":70,"contacts":120,"geoPoint":122},"MSK at Ralph Lauren","10035",[121],{"name":113,"role":74,"phone":75},{"lat":123,"lon":124},40.71427,-74.00597,{"facility":13,"status":8,"city":100,"state":100,"zip":126,"country":70,"contacts":127,"geoPoint":129},"10065",[128],{"name":113,"role":74,"phone":75},{"lat":123,"lon":124},{"facility":131,"status":8,"city":132,"state":100,"zip":133,"country":70,"contacts":134,"geoPoint":136},"Memorial Sloan Kettering Nassau","Rockville Centre","11553",[135],{"name":73,"role":74,"phone":75},{"lat":137,"lon":138},40.65871,-73.64124,[140,142],{"name":73,"role":74,"phone":75,"email":141},"cerceka@mskcc.org",{"name":143,"role":74,"phone":144,"email":145},"Rona Yaeger, MD","646-888-5109","yaegerr@mskcc.org",[147],{"name":73,"affiliation":13,"role":148},"PRINCIPAL_INVESTIGATOR",[],[151],{"label":13,"url":152},"http:\u002F\u002Fwww.mskcc.org",{"nct_id":4,"conditions":154,"biomarkers":156},[19,155],"Malignant Digestive System Neoplasm",[],{"nct_id":4,"found":158,"summary":159,"prompt_version":169},true,{"design":160,"status":161,"heading":162,"summary":163,"follow_up":164,"word_count":165,"commitments":166,"compensation":167,"drugs_mentioned":168},"This is an observational study, meaning researchers will collect information without giving any specific treatments. It plans to enroll 1366 participants.","completed","Understanding Young Onset Colorectal Cancer","This study is collecting information to better understand colorectal cancer (cancer of the colon or rectum) that is diagnosed in younger individuals (before age 50). Researchers are creating a database of information from patients with young onset colorectal cancer. You may be able to participate if you have been diagnosed with gastrointestinal cancer and are between 18 and 49 years old. The main goal is to build this database over one year to help researchers learn how young onset colorectal cancer might be similar to or different from colorectal cancer diagnosed later in life, and to support future research.","The primary goal is to establish a database over one year.",99,"Participants will complete a risk factor questionnaire, preferably at their first visit.","Not stated in the trial record.",[],"v2"]