[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT05096923":3,"trial-entities:NCT05096923":89,"trial-summary:NCT05096923":93},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":16,"conditions":17,"keywords":22,"study_type":25,"primary_purpose":16,"phases":26,"enrollment_info":27,"interventions":30,"primary_outcomes":31,"secondary_outcomes":39,"sex":46,"minimum_age":47,"maximum_age":48,"healthy_volunteers":14,"eligibility_criteria":49,"std_ages":57,"locations":60,"central_contacts":80,"overall_officials":83,"references":87,"see_also_links":88},"NCT05096923","LCCC 2116","UNC Childhood, Adolescent, and Young Adult Cancer Cohort","RECRUITING","2031-12-31","2026-05","2026-05-12","2021-12-17","UNC Lineberger Comprehensive Cancer Center","OTHER",false,"Purpose: This study aims to create a registry of childhood, adolescent, and young adult patients with cancer (\\\u003C40 years-old at cancer diagnosis), entitled the 'UNC Childhood, Adolescent, and Young Adult Cancer Cohort' (UNC-CAYACC). This resource will serve to support cancer outcomes research among pediatric and young adult cancer patients with a primary focus on enrolling patients treated as adolescents or young adults (AYAs, 15-39 years).\n\nProcedures: As appropriate for age, participants will complete physical and cognitive functional assessments; questionnaires to assess health-related quality of life and other patient-reported outcomes; will undergo body composition and anthropometric measurements; and will be asked to provide biospecimens for biobanking. Assessments will be collected (as possible) at diagnosis, during active treatment, following treatment completion, and annually in survivorship to assess outcomes throughout the treatment and survivorship trajectory. Sociodemographic and clinical information such as cancer treatment modalities and cumulative doses will be collected by medical record abstraction. Participants will be eligible to enroll at any time from diagnosis through survivorship. This registry will provide data to better understand the manifestations of accelerated aging and key contributing factors among children, adolescents, and young adults with cancer.",null,[18,19,20,21],"Pediatric Cancer","Cancer","Cancer Metastatic","Survivorship",[23,24],"Adolescent and young adult","AYA","OBSERVATIONAL",[],{"count":28,"type":29},500,"ESTIMATED",[],[32,36],{"measure":33,"description":34,"timeFrame":35},"Registry development","Creation of a registry of pediatric and young adult patients with cancer treated within the University of North Carolina Health System","Five years",{"measure":37,"description":38,"timeFrame":35},"Functional assessments","Assess feasibility for completing repeated physical and cognitive functional assessments among young cancer survivors. These assessments include measures of physical and general frailty.",[40,43],{"measure":41,"description":42,"timeFrame":35},"Collection of sociodemographic, cancer, and treatment variables","Assess feasibility for collection of sociodemographic (including social determinants of health), cancer (e.g., site and stage), and treatment (e.g., modalities and cumulative doses) variables using patient questionnaires and medical record abstraction.",{"measure":44,"description":45,"timeFrame":35},"Collection of patient-reported outcome measures","Assess feasibility for the repeated collection of patient-reported measures of health-related quality of life, health behaviors, and functional status.","ALL","1 Year","39 Years",{"inclusion":50,"exclusion":53,"raw_text":56},[51,52],"Patient ages 0-39 years at the time of cancer diagnosis (ages 1-39 years at enrollment) who are at any point in treatment and survivorship trajectory","English or Spanish speaking",[54,55],"Unwilling to sign informed consent","Speak a language other than English or Spanish.","Inclusion Criteria:\n\n* Patient ages 0-39 years at the time of cancer diagnosis (ages 1-39 years at enrollment) who are at any point in treatment and survivorship trajectory\n* English or Spanish speaking\n\nExclusion Criteria:\n\n* Unwilling to sign informed consent\n* Speak a language other than English or Spanish.",[58,59],"CHILD","ADULT",[61],{"facility":62,"status":7,"city":63,"state":64,"zip":65,"country":66,"contacts":67,"geoPoint":77},"University of North Carolina at Chapel Hill","Chapel Hill","North Carolina","27599","United States",[68,73],{"name":69,"role":70,"phone":71,"email":72},"Andrew Smitherman, MD","CONTACT","919-966-1178","andrew_smitherman@med.unc.edu",{"name":74,"role":70,"phone":75,"email":76},"Lauren Lux, MSW","984-974-8686","lauren_lux@med.unc.edu",{"lat":78,"lon":79},35.9132,-79.05584,[81,82],{"name":69,"role":70,"phone":71,"email":72},{"name":74,"role":70,"phone":75,"email":76},[84],{"name":69,"affiliation":85,"role":86},"University of North Carolina, Chapel Hill","PRINCIPAL_INVESTIGATOR",[],[],{"nct_id":4,"conditions":90,"biomarkers":92},[91],"Malignant Neoplasm",[],{"nct_id":4,"found":94,"summary":95,"prompt_version":105},true,{"design":96,"status":97,"heading":98,"summary":99,"follow_up":100,"word_count":101,"commitments":102,"compensation":103,"drugs_mentioned":104},"This is an observational study, meaning researchers will collect information without giving any specific treatments. It plans to enroll about 500 participants.","completed","UNC Childhood, Adolescent, and Young Adult Cancer Cohort (UNC-CAYACC)","This study, called the UNC Childhood, Adolescent, and Young Adult Cancer Cohort (UNC-CAYACC), is creating a registry of children, adolescents, and young adults (up to age 39) who have been diagnosed with cancer. The goal is to gather information to help researchers better understand cancer outcomes in these age groups, especially for those aged 15-39. You can join if you are between 1 and 39 years old, speak English or Spanish, and have been diagnosed with cancer. The study will involve physical and mental assessments, questionnaires about your health and quality of life, body measurements, and providing samples for future research. The main goals are to build this registry and complete functional assessments over five years.","The study aims to develop the registry and complete functional assessments over five years.",116,"You would complete physical and cognitive assessments, fill out questionnaires, have body measurements taken, and provide biospecimens (like blood or tissue samples).","Not stated in the trial record.",[],"v2"]