[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT05405075":3,"trial-entities:NCT05405075":105,"trial-summary:NCT05405075":109},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":16,"conditions":17,"keywords":19,"study_type":20,"primary_purpose":16,"phases":21,"enrollment_info":22,"interventions":25,"primary_outcomes":26,"secondary_outcomes":31,"sex":32,"minimum_age":33,"maximum_age":16,"healthy_volunteers":16,"eligibility_criteria":34,"std_ages":41,"locations":44,"central_contacts":98,"overall_officials":102,"references":103,"see_also_links":104},"NCT05405075","ADRC-001","Arizona Alzheimer's Disease Research Center (ADRC)","UNKNOWN","2026-06-30","2024-07","2024-08-19","2021-10-01","Banner Health","OTHER",false,"The Arizona Alzheimer's Disease Research Center (ADRC) is the National Institute on Aging's (NIA's) first statewide AD Center (ADC), the only ADC in the Southwestern United States, and a leading example of statewide collaboration in biomedical research. It capitalizes on Arizona's strengths in brain imaging, genomics, computer science and biomathematics, the basic, cognitive and behavioral neurosciences, clinical, and neuropathological studies of AD, the discovery and evaluation of investigational treatments, and the study of normal cognitive aging.",null,[18],"Alzheimer Disease",[],"OBSERVATIONAL",[],{"count":23,"type":24},550,"ESTIMATED",[],[27],{"measure":28,"description":29,"timeFrame":30},"Cognitive Status","The ADRC uses a prospective, standardized, and longitudinal clinical evaluation of participants to determine their cognitive status. This includes tests that assess short and long term memory, ability to complete daily tasks, and processing of information.","12 months",[],"ALL","40 Years",{"inclusion":35,"exclusion":38,"raw_text":40},[36,37],"Cognitively normal persons, individuals with mild cognitive impairment or dementia who are at least 40 years of age.","Willing to undergo health and cognitive assessments, and collection and banking of blood with venipuncture for genetic research, biomarker research, and DNA banking.",[39],"1\\. Participants whose diagnosis is unclear and confounded by multiple possible factors are excluded. Participants with diagnoses of non-AD dementias are not excluded.","Inclusion Criteria:\n\n* Cognitively normal persons, individuals with mild cognitive impairment or dementia who are at least 40 years of age.\n* Willing to undergo health and cognitive assessments, and collection and banking of blood with venipuncture for genetic research, biomarker research, and DNA banking.\n\nExclusion Criteria:\n\n* 1\\. Participants whose diagnosis is unclear and confounded by multiple possible factors are excluded. Participants with diagnoses of non-AD dementias are not excluded.\n\n  2\\. Participants whose primary diagnosis is cognitive impairment due to a penetrating or single severe closed head injury, multiple sclerosis, brain tumor, metabolic or toxic encephalopathy, post-infectious (e.g., viral encephalitis, bacterial meningitis), paraneoplastic, primary psychiatric illness, or otherwise not deemed relevant to the intent of the Alzheimer Disease Center program are excluded.\n\n  3\\. Procedure specific exclusion criteria also apply but this does not impact the participants ability to be included in the study.",[42,43],"ADULT","OLDER_ADULT",[45,61,68,78,88],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"contacts":52,"geoPoint":58},"Banner Alzheimer's Institute","RECRUITING","Phoenix","Arizona","85006","United States",[53],{"name":54,"role":55,"phone":56,"email":57},"Trisha Walsh","CONTACT","602-839-6029","adrc@bannerhealth.com",{"lat":59,"lon":60},33.44838,-112.07404,{"facility":62,"status":47,"city":48,"state":49,"zip":63,"country":51,"contacts":64,"geoPoint":67},"Barrow Neurological Institute","85013",[65],{"name":66,"role":55,"email":57},"Jonathan Garcia Suarez",{"lat":59,"lon":60},{"facility":69,"status":47,"city":70,"state":49,"zip":71,"country":51,"contacts":72,"geoPoint":75},"Mayo Clinic","Scottsdale","85259",[73],{"name":74,"role":55,"email":57},"Deborah Brostrom",{"lat":76,"lon":77},33.50921,-111.89903,{"facility":79,"status":47,"city":80,"state":49,"zip":81,"country":51,"contacts":82,"geoPoint":85},"Banner Sun Health Research Institute","Sun City","85351",[83],{"name":84,"role":55,"email":57},"Angela Kuramoto",{"lat":86,"lon":87},33.59754,-112.27182,{"facility":89,"status":47,"city":90,"state":49,"zip":91,"country":51,"contacts":92,"geoPoint":95},"Banner Alzheimer's Institute - Tucson","Tucson","85718",[93],{"name":94,"role":55,"email":57},"Jaynie Anguiano",{"lat":96,"lon":97},32.22174,-110.92648,[99],{"name":54,"role":55,"phone":100,"email":101},"602.839.6029","ADRC@bannerhealth.com",[],[],[],{"nct_id":4,"conditions":106,"biomarkers":108},[107],"Alzheimer's Disease",[],{"nct_id":4,"found":110,"summary":111,"prompt_version":120},true,{"design":112,"status":113,"heading":6,"summary":114,"follow_up":115,"word_count":116,"commitments":117,"compensation":118,"drugs_mentioned":119},"This is an observational study, meaning researchers will observe participants without providing specific interventions. It aims to enroll 550 participants.","completed","The Arizona Alzheimer's Disease Research Center (ADRC) is conducting an observational study to better understand Alzheimer's disease. This study is looking at people who are cognitively normal, have mild cognitive impairment, or have dementia. You can join if you are at least 40 years old. The researchers will assess your cognitive status (thinking and memory abilities) after 12 months to see how it changes over time. The study aims to enroll 550 participants, but its current recruitment status is unclear.","Your cognitive status will be measured at 12 months.",80,"You would undergo health and cognitive assessments. You would also have blood drawn for genetic and biomarker research, and for DNA banking.","Not stated in the trial record.",[],"v2"]