[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT05623020":3,"trial-entities:NCT05623020":1080,"trial-summary:NCT05623020":1083},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":20,"study_type":29,"primary_purpose":30,"phases":31,"enrollment_info":33,"interventions":36,"primary_outcomes":56,"secondary_outcomes":66,"sex":117,"minimum_age":118,"maximum_age":17,"healthy_volunteers":119,"eligibility_criteria":120,"std_ages":146,"locations":149,"central_contacts":1066,"overall_officials":1072,"references":1075,"see_also_links":1076},"NCT05623020","C1071006","A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant","AN OPEN-LABEL, 2-ARM, MULTICENTER, RANDOMIZED PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ELRANATAMAB (PF-06863135) + DARATUMUMAB + LENALIDOMIDE VERSUS DARATUMUMAB + BORTEZOMIB + LENALIDOMIDE + DEXAMETHASONE IN TRANSPLANT-INELIGIBLE PARTICIPANTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA","RECRUITING","2033-10-03","2026-07","2026-07-09","2022-11-10","Pfizer","INDUSTRY",true,"Elranatamab is a bispecific antibody: binding of elranatamab to CD3-expressing T-cells and BCMA-expressing multiple myeloma cells causes targeted T-cell-mediated cytotoxicity. The main purpose of the study is to evaluate if the combination of Elranatamab, Daratumumab and Lenalidomide offers superior clinical benefit compared with the combination of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in people with newly diagnosed multiple myeloma.\n\nThere are 2 parts to this study. Part 1 will characterize the safety and tolerability of elranatamab in combination with daratumumab and lenalidomide or in combination with lenalidomide and will identify the optimal dose(s) of the combination regimen. Part 2 of the study will evaluate the rate of minimal residual disease (MRD) negative CR and the progression free survival (PFS) of the combination of elranatamab, daratumumab, and lenalidomide compared with the combination of daratumumab, bortezomib, lenalidomide, and dexamethasone in participants with newly diagnosed multiple myeloma.",null,[19],"Multiple Myeloma",[21,22,23,24,25,26,27,28],"Elranatamab","PF-06863135","B-Cell Maturation Antigen","Daratumumab","Lenalidomide","Multiple myeloma","MagnetisMM-6","Bortezomib","INTERVENTIONAL","TREATMENT",[32],"PHASE3",{"count":34,"type":35},1116,"ESTIMATED",[37,45,48,50,54],{"type":38,"name":21,"description":39,"armGroupLabels":40},"DRUG","Part 1 Dose Level 1 is not randomized. All other cohorts are randomized.",[41,42,43,44],"Part 1, Dose Level 1: Elranatamab + Daratumumab + Lenalidomide","Part 1, Multiple Dose Levels, Elranatamab + Daratumumab + Lenalidomide","Part 1: Elranatamab + Lenalidomide","Part 2 Randomized Arm A: Elranatamab + Daratumumab + Lenalidomide",{"type":38,"name":24,"description":39,"armGroupLabels":46},[41,42,44,47],"Part 2 Randomized Arm B: Daratumumab + Bortezomib + Lenalidomide + Dexamethasone",{"type":38,"name":25,"description":39,"armGroupLabels":49},[41,42,43,44,47],{"type":38,"name":51,"description":52,"armGroupLabels":53},"Dexamethasone","Randomized",[47],{"type":38,"name":28,"description":52,"armGroupLabels":55},[47],[57,60,63],{"measure":58,"timeFrame":59},"Part 1 Dose Limiting Toxicity","From the first dose of elranatamab\u002Ffirst full dose in combination with EDR until 28 days (+\u002F- visit window) from the first administration of elranatamab with daratumumab and lenalidomide",{"measure":61,"timeFrame":62},"Part 2: Progression free survival per IMWG","From randomization up to 97 months.",{"measure":64,"timeFrame":65},"Part 2: Minimal Residual Disease negative CR rate","At 12 months after randomization",[67,70,72,74,77,79,82,84,86,89,92,95,98,100,104,107,110,114],{"measure":68,"timeFrame":69},"Overall Survival","From date of randomization up to 97 months",{"measure":71,"timeFrame":69},"Overall minimal residual disease negative CR rate",{"measure":73,"timeFrame":69},"Sustained MRD negative CR rate (Part 2)",{"measure":75,"timeFrame":76},"Duration of minimal residual disease negative CR (Part 2)","From date of minimal residual disease negative CR status up to 97 months",{"measure":78,"timeFrame":69},"PFS by investigator",{"measure":80,"timeFrame":81},"PFS2 by investigator (Part 2)","From the date of randomization up to 97 months",{"measure":83,"timeFrame":81},"Objective Response Rate",{"measure":85,"timeFrame":81},"Complete Response Rate",{"measure":87,"timeFrame":88},"Time to Response","From the date of randomization to date of confirmed objective response up to 97 months",{"measure":90,"timeFrame":91},"Duration of Response","From the date of confirmed objective response up to 97 months",{"measure":93,"timeFrame":94},"Duration of Complete Response","From the date of confirmed complete response up to 97 months",{"measure":96,"timeFrame":97},"Frequency of treatment-emergent adverse events","From the date of first dose of study intervention up to 97 months",{"measure":99,"timeFrame":97},"Frequency of abnormal laboratory results",{"measure":101,"description":102,"timeFrame":103},"Pharmacokinetics of elranatamab when used in the elranatamab + daratumumab + lenalidomide or elranatamab + lenalidomide combinations","Predose and post dose concentrations of elranatamab","From date of first dose of study intervention up to 97 months",{"measure":105,"description":106,"timeFrame":103},"Incidence of Anti-Drug Antibody against elranatamab","Immunogenicity of elranatamab",{"measure":108,"description":109,"timeFrame":103},"Pharmacokinetics of daratumumab and lenalidomide when used in the elranatamab+daratumumab+lenalidomide or elranatamab+lenalidomide combinations (Part 1)","Predose concentrations of daratumumab and lenalidomide",{"measure":111,"description":112,"timeFrame":113},"Health-related quality of life by European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30 (Part 2)","Higher scores on the functional scales represent higher levels of functioning. Higher scores on the global health status\u002Fquality of life scale represent higher health status\u002Fquality of life. Higher scores on the symptom scales\u002Fitems represent a greater presence of symptoms.","From date the informed consent is signed up to 97 months",{"measure":115,"description":116,"timeFrame":113},"Health-related quality of life by European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Myeloma 20 (Part 2)","Higher scores on the functioning subscales (body image, future perspective) represent higher levels of functioning, whereas higher scores on the symptom subscales (disease symptoms, side effects) represent a greater presence of symptoms","ALL","18 Years",false,{"inclusion":121,"exclusion":134,"raw_text":145},[122,123,124,125,126,127,128,129,130,131,132,133],"Diagnosis of multiple myeloma (MM) as defined by IMWG criteria (Rajkumar et al., 2014)","Measurable disease based on IMWG criteria as defined by at least 1 of the following:","Serum M-protein ≥0.5 g\u002FdL (Part 1) and ≥1 g\u002FdL (Part 2);","Urinary M-protein excretion ≥200 mg\u002F24 hours;","Involved FLC ≥10 mg\u002FdL (≥100 mg\u002FL) AND abnormal serum immunoglobulin kappa to lambda FLC ratio (\\\u003C0.26 or \\>1.65).","Part 1: Participants with relapsed\u002Frefractory multiple myeloma (RRMM) who have received 1-2 prior lines of therapy including at least one immunomodulatory drug and one proteasome inhibitor: or participants with newly-diagnosed multiple myeloma (NDMM) that are transplant-ineligible as defined by age ≥65 years or transplant-ineligible as defined by age \\\u003C65 years with comorbidities impacting the possibility of transplant.","Part 2: participants with newly-diagnosed multiple myeloma that are transplant-ineligible defined as:","Participants not considered candidates for high-dose chemotherapy and ASCT due to age or","Participants with important comorbidities likely to have a negative impact on tolerability of high dose chemotherapy and ASCT.","ECOG performance status ≤2.","Not pregnant and willing to use contraception","For participants with RRMM: Resolved acute effects of any prior therapy to baseline severity or CTCAE Grade ≤1.",[135,136,137,138,139,140,141,142,143,144],"Smoldering Multiple Myeloma.","Monoclonal gammopathy of undetermined significance.","Waldenströms Macroglobulinemia","Plasma cell leukemia.","Active, uncontrolled bacterial, fungal, or viral infection, including (but not limited to) COVID-19\u002FSARS-CoV-2, HBV, HCV, and known HIV or AIDS-related illness.","Any other active malignancy within 3 years prior to enrollment, except for adequately treated basal cell or squamous cell skin cancer, carcinoma in situ, or Stage 0\u002F1 with minimal risk of recurrence per investigator.","For participants with RRMM: Previous treatment with a BCMA-directed therapy or anti-CD38-directed therapy within 6 months preceding the first dose of study intervention in this study. Stem cell transplant ≤3 months prior to first dose of study intervention or active GVHD.","For participants with NDMM: Previous systemic treatment for MM except for a short course of corticosteroids (ie, total of 160 mg dexamethasone or equivalent before the first dose of study intervention). A cumulative dose of systemic corticosteroids equivalent to ≥20 mg of dexamethasone during screening.","Live attenuated vaccine administered within 4 weeks of the first dose of study intervention.","Administration of investigational product (eg, drug or vaccine) concurrent with study intervention or within 30 days (or as determined by the local requirement) preceding the first dose of study intervention used in this study.","Inclusion Criteria:\n\n* Diagnosis of multiple myeloma (MM) as defined by IMWG criteria (Rajkumar et al., 2014)\n* Measurable disease based on IMWG criteria as defined by at least 1 of the following:\n\n  * Serum M-protein ≥0.5 g\u002FdL (Part 1) and ≥1 g\u002FdL (Part 2);\n  * Urinary M-protein excretion ≥200 mg\u002F24 hours;\n  * Involved FLC ≥10 mg\u002FdL (≥100 mg\u002FL) AND abnormal serum immunoglobulin kappa to lambda FLC ratio (\\\u003C0.26 or \\>1.65).\n* Part 1: Participants with relapsed\u002Frefractory multiple myeloma (RRMM) who have received 1-2 prior lines of therapy including at least one immunomodulatory drug and one proteasome inhibitor: or participants with newly-diagnosed multiple myeloma (NDMM) that are transplant-ineligible as defined by age ≥65 years or transplant-ineligible as defined by age \\\u003C65 years with comorbidities impacting the possibility of transplant.\n* Part 2: participants with newly-diagnosed multiple myeloma that are transplant-ineligible defined as:\n\n  * Participants not considered candidates for high-dose chemotherapy and ASCT due to age or\n  * Participants with important comorbidities likely to have a negative impact on tolerability of high dose chemotherapy and ASCT.\n* ECOG performance status ≤2.\n* Not pregnant and willing to use contraception\n* For participants with RRMM: Resolved acute effects of any prior therapy to baseline severity or CTCAE Grade ≤1.\n\nExclusion Criteria:\n\n* Smoldering Multiple Myeloma.\n* Monoclonal gammopathy of undetermined significance.\n* Waldenströms Macroglobulinemia\n* Plasma cell leukemia.\n* Active, uncontrolled bacterial, fungal, or viral infection, including (but not limited to) COVID-19\u002FSARS-CoV-2, HBV, HCV, and known HIV or AIDS-related illness.\n* Any other active malignancy within 3 years prior to enrollment, except for adequately treated basal cell or squamous cell skin cancer, carcinoma in situ, or Stage 0\u002F1 with minimal risk of recurrence per investigator.\n* For participants with RRMM: Previous treatment with a BCMA-directed therapy or anti-CD38-directed therapy within 6 months preceding the first dose of study intervention in this study. Stem cell transplant ≤3 months prior to first dose of study intervention or active GVHD.\n* For participants with NDMM: Previous systemic treatment for MM except for a short course of corticosteroids (ie, total of 160 mg dexamethasone or equivalent before the first dose of study intervention). A cumulative dose of systemic corticosteroids equivalent to ≥20 mg of dexamethasone during screening.\n* Live attenuated vaccine administered within 4 weeks of the first dose of study intervention.\n* Administration of investigational product (eg, drug or vaccine) concurrent with study intervention or within 30 days (or as determined by the local requirement) preceding the first dose of study intervention used in this study.",[147,148],"ADULT","OLDER_ADULT",[150,160,168,175,182,190,197,203,207,214,222,231,239,246,250,257,266,274,281,288,297,305,313,322,331,339,347,351,359,368,376,384,388,396,404,411,419,427,435,443,450,459,466,473,482,490,497,504,513,521,529,536,543,552,559,567,574,581,590,594,602,605,613,622,626,633,641,649,658,665,672,680,688,696,704,712,720,727,734,741,744,751,757,765,770,778,783,788,795,802,809,816,825,834,842,848,858,866,874,882,888,896,904,908,912,915,924,932,936,943,951,959,967,975,982,990,997,1001,1005,1012,1016,1024,1032,1036,1043,1050,1059],{"facility":151,"status":152,"city":153,"state":154,"zip":155,"country":156,"geoPoint":157},"Jupiter Medical Center\u002FAnderson Family Cancer Institute","NOT_YET_RECRUITING","Jupiter","Florida","33458","United States",{"lat":158,"lon":159},26.93422,-80.09421,{"facility":161,"status":8,"city":162,"state":163,"zip":164,"country":156,"geoPoint":165},"MSK Basking Ridge","Basking Ridge","New Jersey","07920",{"lat":166,"lon":167},40.70621,-74.54932,{"facility":169,"status":8,"city":170,"state":163,"zip":171,"country":156,"geoPoint":172},"MSK Monmouth","Middletown","07748",{"lat":173,"lon":174},40.39428,-74.11709,{"facility":176,"status":8,"city":177,"state":163,"zip":178,"country":156,"geoPoint":179},"MSK Bergen","Montvale","07645",{"lat":180,"lon":181},41.04676,-74.02292,{"facility":183,"status":8,"city":184,"state":185,"zip":186,"country":156,"geoPoint":187},"MSK Commack","Commack","New York","11725",{"lat":188,"lon":189},40.84288,-73.29289,{"facility":191,"status":8,"city":192,"state":185,"zip":193,"country":156,"geoPoint":194},"MSK Westchester","Harrison","10604",{"lat":195,"lon":196},40.96899,-73.71263,{"facility":198,"status":8,"city":185,"state":185,"zip":199,"country":156,"geoPoint":200},"Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street).","10021",{"lat":201,"lon":202},40.71427,-74.00597,{"facility":204,"status":8,"city":185,"state":185,"zip":205,"country":156,"geoPoint":206},"Memorial Sloan Kettering Cancer Center-Main Campus","10065",{"lat":201,"lon":202},{"facility":208,"status":8,"city":209,"state":185,"zip":210,"country":156,"geoPoint":211},"MSK Nassau","Uniondale","11553",{"lat":212,"lon":213},40.70038,-73.59291,{"facility":215,"status":8,"city":216,"state":217,"zip":218,"country":156,"geoPoint":219},"The University of Texas MD Anderson Cancer Center","Houston","Texas","77030",{"lat":220,"lon":221},29.76328,-95.36327,{"facility":223,"status":8,"city":224,"state":225,"zip":226,"country":227,"geoPoint":228},"Pindara Private Hospital","Benowa","Queensland","4217","Australia",{"lat":229,"lon":230},-28.0077,153.38583,{"facility":232,"status":8,"city":233,"state":234,"zip":235,"country":227,"geoPoint":236},"St Vincent's Hospital Melbourne","Fitzroy","Victoria","3065",{"lat":237,"lon":238},-37.79839,144.97833,{"facility":240,"status":8,"city":241,"state":234,"zip":242,"country":227,"geoPoint":243},"Epworth Freemasons","Melbourne","3002",{"lat":244,"lon":245},-37.814,144.96332,{"facility":247,"status":8,"city":241,"state":234,"zip":248,"country":227,"geoPoint":249},"The Alfred Hospital","3004",{"lat":244,"lon":245},{"facility":251,"status":8,"city":252,"state":234,"zip":253,"country":227,"geoPoint":254},"Epworth Healthcare","Richmond","3121",{"lat":255,"lon":256},-37.81819,145.00176,{"facility":258,"status":8,"city":259,"state":260,"zip":261,"country":262,"geoPoint":263},"Medizinische Universität Graz","Graz","Styria","8036","Austria",{"lat":264,"lon":265},47.06733,15.44197,{"facility":267,"status":152,"city":268,"state":269,"zip":270,"country":262,"geoPoint":271},"Landeskrankenhaus Feldkirch","Rankweil","Vorarlberg","6830",{"lat":272,"lon":273},47.27108,9.64308,{"facility":275,"status":152,"city":276,"zip":277,"country":262,"geoPoint":278},"Uniklinikum Salzburg","Salzburg","5020",{"lat":279,"lon":280},47.79941,13.04399,{"facility":282,"status":152,"city":283,"zip":284,"country":262,"geoPoint":285},"Medizinische Universität Wien","Vienna","1090",{"lat":286,"lon":287},48.20849,16.37208,{"facility":289,"status":152,"city":290,"state":291,"zip":292,"country":293,"geoPoint":294},"Clinique Saint Pierre","Ottignies","Brabant Wallon","1340","Belgium",{"lat":295,"lon":296},50.66535,4.56679,{"facility":298,"status":8,"city":299,"state":300,"zip":301,"country":293,"geoPoint":302},"Grand Hôpital de Charleroi","Gilly","Hainaut","6060",{"lat":303,"lon":304},50.42449,4.4789,{"facility":306,"status":8,"city":307,"state":308,"zip":309,"country":293,"geoPoint":310},"AZ Delta vzw","Roeselare","West-vlaanderen","8800",{"lat":311,"lon":312},50.94653,3.12269,{"facility":314,"status":152,"city":315,"state":316,"zip":317,"country":318,"geoPoint":319},"Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (USP)","Ribeirão Preto","São Paulo","14051-140","Brazil",{"lat":320,"lon":321},-21.1775,-47.81028,{"facility":323,"status":152,"city":324,"state":325,"zip":326,"country":327,"geoPoint":328},"Cross Cancer Institute","Edmonton","Alberta","T6G 1Z2","Canada",{"lat":329,"lon":330},53.55014,-113.46871,{"facility":332,"status":152,"city":333,"state":334,"zip":335,"country":327,"geoPoint":336},"Dr. Everett Chalmers Regional Hospital","Fredericton","New Brunswick","E3B 5N5",{"lat":337,"lon":338},45.94541,-66.66558,{"facility":340,"status":8,"city":341,"state":342,"zip":343,"country":327,"geoPoint":344},"QEII Health Sciences Centre","Halifax","Nova Scotia","B3H 2Y9",{"lat":345,"lon":346},44.64269,-63.57688,{"facility":348,"status":8,"city":341,"state":342,"zip":349,"country":327,"geoPoint":350},"Nova Scotia Health Authority","B3S 0H6",{"lat":345,"lon":346},{"facility":352,"status":8,"city":353,"state":354,"zip":355,"country":327,"geoPoint":356},"Princess Margaret Cancer Centre","Toronto","Ontario","M5G 2M9",{"lat":357,"lon":358},43.70643,-79.39864,{"facility":360,"status":8,"city":361,"state":362,"zip":363,"country":364,"geoPoint":365},"Peking University Third Hospital","Beijing","Beijing Municipality","100091","China",{"lat":366,"lon":367},39.9075,116.39723,{"facility":369,"status":8,"city":370,"state":371,"zip":372,"country":364,"geoPoint":373},"Fujian Medical University Union Hospital","Fuzhou","Fujian","350001",{"lat":374,"lon":375},26.06139,119.30611,{"facility":377,"status":8,"city":378,"state":379,"zip":380,"country":364,"geoPoint":381},"Southern Medical University Nanfang Hospital","Guangzhou","Guangdong","510515",{"lat":382,"lon":383},23.11667,113.25,{"facility":385,"status":8,"city":378,"state":379,"zip":386,"country":364,"geoPoint":387},"Sun Yat-sen University Cancer Center","510555",{"lat":382,"lon":383},{"facility":389,"status":8,"city":390,"state":391,"zip":392,"country":364,"geoPoint":393},"Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology","Wuhan","Hubei","430030",{"lat":394,"lon":395},30.58333,114.26667,{"facility":397,"status":8,"city":398,"state":399,"zip":400,"country":364,"geoPoint":401},"Nanjing Drum Tower Hospital","Nanjing","Jiangsu","210008",{"lat":402,"lon":403},32.06167,118.77778,{"facility":405,"status":8,"city":406,"state":399,"zip":407,"country":364,"geoPoint":408},"The First Affiliated Hospital of Soochow University","Suzhou","215006",{"lat":409,"lon":410},31.30408,120.59538,{"facility":412,"status":8,"city":413,"state":414,"zip":415,"country":364,"geoPoint":416},"The first hospital of jilin university","Changchun","Jilin","130021",{"lat":417,"lon":418},43.88,125.32278,{"facility":420,"status":8,"city":421,"state":422,"zip":423,"country":364,"geoPoint":424},"Tongji University - Shanghai Fourth People's Hospital","Shanghai","Shanghai Municipality","200434",{"lat":425,"lon":426},31.22222,121.45806,{"facility":428,"status":8,"city":429,"state":430,"zip":431,"country":364,"geoPoint":432},"Institute of hematology&blood disease hospital","Tianjin","Tianjin Municipality","300020",{"lat":433,"lon":434},39.14222,117.17667,{"facility":436,"status":8,"city":437,"state":438,"zip":439,"country":364,"geoPoint":440},"The first Affiliated Hospital, Zhejiang University School of Medicine","Hangzhou","Zhejiang","310003",{"lat":441,"lon":442},30.29365,120.16142,{"facility":444,"status":8,"city":445,"state":438,"zip":446,"country":364,"geoPoint":447},"The first Affiliated hospital of Wenzhou medical University","Wenzhou","325000",{"lat":448,"lon":449},27.99942,120.66682,{"facility":451,"status":8,"city":452,"state":453,"zip":454,"country":455,"geoPoint":456},"Fakultní nemocnice Brno Bohunice","Brno","Brno-město","625 00","Czechia",{"lat":457,"lon":458},49.19522,16.60796,{"facility":460,"status":8,"city":461,"zip":462,"country":455,"geoPoint":463},"Fakultni nemocnice Olomouc","Olomouc","779 00",{"lat":464,"lon":465},49.59552,17.25175,{"facility":467,"status":8,"city":468,"zip":469,"country":455,"geoPoint":470},"Vseobecna fakultni nemocnice v Praze","Prague","12808",{"lat":471,"lon":472},50.08804,14.42076,{"facility":474,"status":8,"city":475,"state":476,"zip":477,"country":478,"geoPoint":479},"Kuopion Yliopistollinen Sairaala","Kuopio","Northern Savonia","70210","Finland",{"lat":480,"lon":481},62.89238,27.67703,{"facility":483,"status":8,"city":484,"state":485,"zip":486,"country":478,"geoPoint":487},"Turku University Hospital","Turku","Southwest Finland","20520",{"lat":488,"lon":489},60.45148,22.26869,{"facility":491,"status":8,"city":492,"zip":493,"country":478,"geoPoint":494},"Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus)","Helsinki","00029",{"lat":495,"lon":496},60.16952,24.93545,{"facility":498,"status":8,"city":499,"zip":500,"country":478,"geoPoint":501},"Oulu University Hospital","Oulu","90220",{"lat":502,"lon":503},65.01236,25.46816,{"facility":505,"status":8,"city":506,"state":507,"zip":508,"country":509,"geoPoint":510},"Centre Hospitalier Universitaire de Nice - Hôpital l'Archet","Nice","Alpes-maritimes","06200","France",{"lat":511,"lon":512},43.70313,7.26608,{"facility":514,"status":8,"city":515,"state":516,"zip":517,"country":509,"geoPoint":518},"Institut Universitaire du Cancer Toulouse - Oncopole - CHU de 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