[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT05694559":3,"trial-entities:NCT05694559":81,"trial-summary:NCT05694559":86},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":16,"conditions":17,"keywords":20,"study_type":21,"primary_purpose":22,"phases":23,"enrollment_info":25,"interventions":28,"primary_outcomes":38,"secondary_outcomes":42,"sex":43,"minimum_age":44,"maximum_age":45,"healthy_volunteers":46,"eligibility_criteria":47,"std_ages":52,"locations":55,"central_contacts":71,"overall_officials":73,"references":77,"see_also_links":78},"NCT05694559","2022-0328","Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics","RECRUITING","2027-02-02","2026-08","2026-08-10","2022-11-23","M.D. Anderson Cancer Center","OTHER",false,"To identify Black individuals who are eligible for genetic testing through trusted community organizations, and to connect Black individuals and their families to genetic testing and counseling so that they can know their cancer risk and how to decrease it.","Primary Objectives:\n\n* To identify 300 Black families, at least one individual per family, eligible for genetic testing using our validated simple genetic risk screening tool (GRST) 1, via collaboration with trusted community organizations. For individuals eligible for genetic testing, we will counsel them about genetic testing, including reviewing GRST results, explaining why they are eligible for genetic testing as part of standard-of-care, explaining what this entails, offering on-site or remote genetic testing, and explaining that they will be connected to a genetic counselor if they have a pathogenic mutation (PV) of a variant of unknown significance (VUS), including resources for family cascade genetic testing.\n* To provide genetic testing to 150 Black individuals and families and provide genetic counseling and risk reduction resources to individuals with a PV or VUS, including cascade genetic testing for their family members.",[18,19],"Breast Cancer","Colorectal Cancer",[],"INTERVENTIONAL","SCREENING",[24],"NA",{"count":26,"type":27},1000,"ESTIMATED",[29,34],{"type":30,"name":31,"description":32,"armGroupLabels":33},"BEHAVIORAL","Genetic Testing and Counseling","Participants will complete testing",[31],{"type":30,"name":35,"description":36,"armGroupLabels":37},"Screening Form","Participants will complete forms with demographics and history",[35],[39],{"measure":40,"timeFrame":41},"genetic risk screening tool (GRST) questionnaire","through study completion; an average of 1 year.",[],"ALL","18 Years",null,true,{"inclusion":48,"exclusion":50,"raw_text":51},[49],"Any participant over 18 years old who self-identifies as Black or African-American and signs an informed consent form, also referred to as the 'Permission to Contact' form, to be part of our study.",[],"Inclusion Criteria:\n\n* Any participant over 18 years old who self-identifies as Black or African-American and signs an informed consent form, also referred to as the 'Permission to Contact' form, to be part of our study.\n\nExclusion Criteria:\n\nNone",[53,54],"ADULT","OLDER_ADULT",[56],{"facility":57,"status":7,"city":58,"state":59,"zip":60,"country":61,"contacts":62,"geoPoint":68},"MD Anderson Cancer Center","Houston","Texas","77030","United States",[63],{"name":64,"role":65,"phone":66,"email":67},"Banu Arun, MD","CONTACT","713-792-2817","barun@mdanderson.org",{"lat":69,"lon":70},29.76328,-95.36327,[72],{"name":64,"role":65,"phone":66,"email":67},[74],{"name":64,"affiliation":75,"role":76},"MD Anderson Cancer Cneter","PRINCIPAL_INVESTIGATOR",[],[79],{"label":57,"url":80},"http:\u002F\u002Fwww.mdanderson.org",{"nct_id":4,"conditions":82,"biomarkers":85},[83,84],"Breast Carcinoma","Colorectal Carcinoma",[],{"nct_id":4,"found":46,"summary":87,"prompt_version":97},{"design":88,"status":89,"heading":90,"summary":91,"follow_up":92,"word_count":93,"commitments":94,"compensation":95,"drugs_mentioned":96},"This is an interventional study planning to enroll 1000 participants. It focuses on connecting individuals to genetic testing and counseling.","completed","Connecting Black Families to Hereditary Cancer Genetic Counseling and Testing in Houston","This study aims to help Black individuals and families in Houston understand their risk for hereditary cancers like breast and colorectal cancer. We are using a simple genetic risk screening tool and offering genetic testing and counseling through community organizations. The goal is to identify individuals eligible for genetic testing, provide them with testing and counseling, and connect those with certain genetic changes to resources for reducing their cancer risk and for their family members to also get tested. We hope to identify 300 Black families and provide genetic testing to 150 Black individuals and families.","Participants will be followed through study completion, which is an average of one year, for the genetic risk screening tool questionnaire.",96,"You will complete forms about your demographics and health history, and if eligible, you will complete genetic testing. The study will follow up on a questionnaire for about one year.","Not stated in the trial record.",[31],"v2"]