[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT05757102":3,"trial-entities:NCT05757102":739,"trial-summary:NCT05757102":742},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":20,"study_type":30,"primary_purpose":31,"phases":32,"enrollment_info":34,"interventions":37,"primary_outcomes":54,"secondary_outcomes":59,"sex":79,"minimum_age":80,"maximum_age":81,"healthy_volunteers":15,"eligibility_criteria":82,"std_ages":97,"locations":99,"central_contacts":728,"overall_officials":733,"references":737,"see_also_links":738},"NCT05757102","206867","A Study to Compare the Efficacy, Safety and Tolerability of FF\u002FUMEC\u002FVI With FF\u002FVI in 12-17-year-olds With Asthma","A Phase 3, 24-week, Randomized, Double-blind, Parallel-group Bayesian Dynamic Borrowing Study Comparing the Efficacy, Safety, Tolerability and Pharmacokinetics of FF\u002FUMEC\u002FVI With FF\u002FVI in 12-17-year-old Participants With Inadequately Controlled Asthma on Stable Maintenance Therapy With ICS\u002FLABA","RECRUITING","2027-01-28","2026-07","2026-07-16","2023-04-25","GlaxoSmithKline","INDUSTRY",false,"The primary purpose of this study is to evaluate the effects of Fluticasone Furoate (FF)\u002F Umeclidinium (UMEC)\u002F Vilanterol (VI) on lung function compared with FF\u002FVI after 24 weeks of treatment.",null,[19],"Asthma",[21,22,23,24,25,26,27,28,29],"Fluticasone Furoate","GW685698","Umeclidinium","GSK573719","Vilanterol","GW642444","Trelegy","Relvar","Breo","INTERVENTIONAL","TREATMENT",[33],"PHASE3",{"count":35,"type":36},292,"ESTIMATED",[38,44,50],{"type":39,"name":40,"description":41,"armGroupLabels":42},"DRUG","FF\u002FUMEC\u002FVI","FF\u002FUMEC\u002FVI will be administered.",[43],"Participants receiving FF\u002FUMEC\u002FVI",{"type":45,"name":46,"description":47,"armGroupLabels":48},"DEVICE","ELLIPTA","FF\u002FUMEC\u002FVI and FF\u002FVI will be administered via ELLIPTA inhaler",[43,49],"Participants receiving FF\u002FVI",{"type":39,"name":51,"description":52,"armGroupLabels":53},"FF\u002FVI","FF\u002FVI will be administered.",[49],[55],{"measure":56,"description":57,"timeFrame":58},"Change from baseline in trough forced expiratory volume in 1 second (FEV1) (Liters) at Week 24","FEV1 will be measured using spirometry.","Baseline (Week 0) and Week 24",[60,63,66,69,73,76],{"measure":61,"description":62,"timeFrame":58},"Change from Baseline in Asthma Control Questionnaire (7 items) (ACQ-7) (Scores on a scale)","ACQ-7 consists of 5 symptom related questions (nocturnal awakening, symptoms on waking in the morning, activity limitation, shortness of breath and wheeze with response options ranging from zero (no impairment\u002Flimitation) to 6 (total impairment\u002F limitation)), a question on rescue use and an additional item relating to lung function which is calculated based on FEV1. A score of less than or equal to (\\\u003C=) 0.75 indicates well-controlled asthma and a score greater than or equal to (\\>=)1.5 indicates poorly controlled asthma.",{"measure":64,"description":65,"timeFrame":58},"Change from Baseline in Asthma Control Questionnaire (6 items) (ACQ-6) (Scores on a scale)","ACQ-6 consists of 5 symptom related questions (nocturnal awakening, symptoms on waking in the morning, activity limitation, shortness of breath and wheeze with response options ranging from zero (no impairment\u002Flimitation) to 6 (total impairment\u002F limitation)) and a question on rescue bronchodilator use. A score of less than or equal to (\\\u003C=) 0.75 indicates well-controlled asthma and a score greater than or equal to (\\>=)1.5 indicates poorly controlled asthma.",{"measure":67,"description":68,"timeFrame":58},"Change from Baseline in Asthma Control Questionnaire (5 items) (ACQ-5) (Scores on a scale)","ACQ-5 consists of 5 symptom related questions (nocturnal awakening, symptoms on waking in the morning, activity limitation, shortness of breath and wheeze with response options ranging from zero (no impairment\u002Flimitation) to 6 (total impairment\u002F limitation). A score of less than or equal to (\\\u003C=) 0.75 indicates well-controlled asthma and a score greater than or equal to (\\>=)1.5 indicates poorly controlled asthma.",{"measure":70,"description":71,"timeFrame":72},"Number of Participants with a clinically important change from baseline in ACQ-7 Score","ACQ-7 consists of 5 symptom related questions (nocturnal awakening, symptoms on waking in the morning, activity limitation, shortness of breath and wheeze with response options ranging from zero (no impairment\u002Flimitation) to 6 (total impairment\u002F limitation)), a question on rescue use and an additional item relating to lung function which is calculated based on FEV1. A score of less than or equal to (\\\u003C=) 0.75 indicates well-controlled asthma and a score greater than or equal to (\\>=)1.5 indicates poorly controlled asthma. A change of 0.5 in score suggests a clinically important change in score.","Week 24",{"measure":74,"description":75,"timeFrame":72},"Number of Participants with a clinically important change from baseline in ACQ-6 Score","ACQ-6 consists of 5 symptom related questions (nocturnal awakening, symptoms on waking in the morning, activity limitation, shortness of breath and wheeze with response options ranging from zero (no impairment\u002Flimitation) to 6 (total impairment\u002F limitation)) and a question on rescue bronchodilator use. A score of less than or equal to (\\\u003C=) 0.75 indicates well-controlled asthma and a score greater than or equal to (\\>=)1.5 indicates poorly controlled asthma. A change of 0.5 in score suggests a clinically important change in score.",{"measure":77,"description":78,"timeFrame":72},"Number of Participants with a clinically important change from baseline in ACQ-5 Score","ACQ-5 consists of 5 symptom related questions (nocturnal awakening, symptoms on waking in the morning, activity limitation, shortness of breath and wheeze with response options ranging from zero (no impairment\u002Flimitation) to 6 (total impairment\u002F limitation). A score of less than or equal to (\\\u003C=) 0.75 indicates well-controlled asthma and a score greater than or equal to (\\>=)1.5 indicates poorly controlled asthma. A change of 0.5 in score suggests a clinically important change in score.","ALL","12 Years","17 Years",{"inclusion":83,"exclusion":90,"raw_text":96},[84,85,86,87,88,89],"Participant must be 12 to 17 years of age (inclusive), at the time of signing the informed consent\u002Fassent.","Participants who have a diagnosis of asthma as defined by the National Institutes of Health \\[NIH, 2020\\] at least 1 year prior to Visit 0.","Participants who have required daily Inhaled corticosteroids (ICS)\u002F Long-Acting Beta2-Agonist (LABA) treatment for at least 12 weeks prior to Visit 0 with no changes to maintenance asthma medications during the 6 weeks immediately prior to Visit 0 (including no changes to a stable total ICS dose of \\>250 to \\\u003C=500 microgram (mcg)\u002Fday fluticasone propionate, or equivalent).","In the 1 year prior to Visit 1: A documented healthcare contact for acute asthma symptoms; OR A documented temporary change in asthma therapy for acute asthma symptoms, according to a prespecified asthma action plan (or equivalent).","Participants with inadequately controlled asthma (ACQ-6 score ≥1.5) at Visit 1, despite ICS\u002FLABA maintenance therapy.","A best pre-bronchodilator FEV1 \\>40% to \\\u003C=90% of the predicted normal value and a ≥12% increase in FEV1 with albuterol\u002Fsalbutamol at Visit 1. Predicted values will be based on the European Respiratory Society (ERS) Global Lung Function Initiative.",[91,92,93,94,95],"Chest X-ray documented pneumonia in the 6 weeks prior to Visit 1.","Any asthma exacerbation requiring a change in maintenance asthma therapy and\u002For the use of systemic corticosteroids for at least 3 days in the 6 weeks prior to Visit 1. (Participants requiring a temporary change in asthma therapy (e.g., oral corticosteroids or increased dose of ICS) to treat an exacerbation in the 6 weeks prior to Visit 1 are not explicitly excluded at Visit 1 provided that, at the Investigator's discretion, the participant's condition is stable after they have resumed their pre-exacerbation maintenance asthma therapy (without modification), returned to their baseline asthma status and they are considered appropriate for enrollment into this study of up to 6 months duration)","History of Life-threatening Asthma","Participants with current evidence of active pulmonary diseases or abnormalities other than asthma (e.g., pneumonia, active tuberculosis, significant bronchiectasis, etc.).","Current smokers and users of other inhaled products for recreation with or without nicotine (defined as participants who use cigarettes, e-cigarettes, other\u002Fvaping-related devices, cigars or pipe tobacco\\]) within 12 months prior to Visit 1.","Inclusion Criteria:\n\n* Participant must be 12 to 17 years of age (inclusive), at the time of signing the informed consent\u002Fassent.\n* Participants who have a diagnosis of asthma as defined by the National Institutes of Health \\[NIH, 2020\\] at least 1 year prior to Visit 0.\n* Participants who have required daily Inhaled corticosteroids (ICS)\u002F Long-Acting Beta2-Agonist (LABA) treatment for at least 12 weeks prior to Visit 0 with no changes to maintenance asthma medications during the 6 weeks immediately prior to Visit 0 (including no changes to a stable total ICS dose of \\>250 to \\\u003C=500 microgram (mcg)\u002Fday fluticasone propionate, or equivalent).\n* In the 1 year prior to Visit 1: A documented healthcare contact for acute asthma symptoms; OR A documented temporary change in asthma therapy for acute asthma symptoms, according to a prespecified asthma action plan (or equivalent).\n* Participants with inadequately controlled asthma (ACQ-6 score ≥1.5) at Visit 1, despite ICS\u002FLABA maintenance therapy.\n* A best pre-bronchodilator FEV1 \\>40% to \\\u003C=90% of the predicted normal value and a ≥12% increase in FEV1 with albuterol\u002Fsalbutamol at Visit 1. Predicted values will be based on the European Respiratory Society (ERS) Global Lung Function Initiative.\n\nExclusion Criteria:\n\n* Chest X-ray documented pneumonia in the 6 weeks prior to Visit 1.\n* Any asthma exacerbation requiring a change in maintenance asthma therapy and\u002For the use of systemic corticosteroids for at least 3 days in the 6 weeks prior to Visit 1. (Participants requiring a temporary change in asthma therapy (e.g., oral corticosteroids or increased dose of ICS) to treat an exacerbation in the 6 weeks prior to Visit 1 are not explicitly excluded at Visit 1 provided that, at the Investigator's discretion, the participant's condition is stable after they have resumed their pre-exacerbation maintenance asthma therapy (without modification), returned to their baseline asthma status and they are considered appropriate for enrollment into this study of up to 6 months duration)\n* History of Life-threatening Asthma\n* Participants with current evidence of active pulmonary diseases or abnormalities other than asthma (e.g., pneumonia, active tuberculosis, significant bronchiectasis, etc.).\n* Current smokers and users of other inhaled products for recreation with or without nicotine (defined as participants who use cigarettes, e-cigarettes, other\u002Fvaping-related devices, cigars or pipe tobacco\\]) within 12 months prior to Visit 1.",[98],"CHILD",[100,121,132,144,156,167,174,186,193,204,207,215,222,234,246,253,265,277,289,300,306,318,330,342,353,359,365,377,385,393,401,409,420,431,442,453,464,475,482,493,504,517,529,538,550,561,569,581,592,600,611,623,634,645,655,664,670,678,686,698,709,720],{"facility":101,"status":8,"city":102,"state":103,"zip":104,"country":105,"contacts":106,"geoPoint":118},"GSK Investigational Site","Birmingham","Alabama","35244","United States",[107,112,115],{"name":108,"role":109,"phone":110,"email":111},"US GSK Clinical Trials Call Center","CONTACT","877-379-3718","GSKClinicalSupportHD@gsk.com",{"name":113,"role":109,"phone":114,"email":111},"EU GSK Clinical Trials Call Centre","+44 (0) 20 8990 4466",{"name":116,"role":117},"Weily Soong","PRINCIPAL_INVESTIGATOR",{"lat":119,"lon":120},33.52066,-86.80249,{"facility":101,"status":8,"city":122,"state":103,"zip":123,"country":105,"contacts":124,"geoPoint":129},"Mobile","36608",[125,126,127],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":128,"role":117},"Lawrence Sindel",{"lat":130,"lon":131},30.69436,-88.04305,{"facility":101,"status":8,"city":133,"state":134,"zip":135,"country":105,"contacts":136,"geoPoint":141},"Paradise Valley","Arizona","85253",[137,138,139],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":140,"role":117},"Michael Manning",{"lat":142,"lon":143},33.53115,-111.94265,{"facility":101,"status":8,"city":145,"state":146,"zip":147,"country":105,"contacts":148,"geoPoint":153},"Bakersfield","California","93301",[149,150,151],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":152,"role":117},"Eric Boren",{"lat":154,"lon":155},35.37329,-119.01871,{"facility":101,"status":8,"city":157,"state":146,"zip":158,"country":105,"contacts":159,"geoPoint":164},"Mission Viejo","92691",[160,161,162],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":163,"role":117},"Warner Carr",{"lat":165,"lon":166},33.60002,-117.672,{"facility":101,"status":168,"city":169,"state":146,"zip":170,"country":105,"geoPoint":171},"COMPLETED","Rolling Hills Estates","90274",{"lat":172,"lon":173},33.78779,-118.35813,{"facility":101,"status":8,"city":175,"state":176,"zip":177,"country":105,"contacts":178,"geoPoint":183},"Colorado Springs","Colorado","80909",[179,180,181],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":182,"role":117},"Eric Caplan",{"lat":184,"lon":185},38.83388,-104.82136,{"facility":101,"status":168,"city":187,"state":188,"zip":189,"country":105,"geoPoint":190},"Aventura","Florida","33180",{"lat":191,"lon":192},25.95648,-80.13921,{"facility":101,"status":8,"city":194,"state":188,"zip":195,"country":105,"contacts":196,"geoPoint":201},"Miami","33165",[197,198,199],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":200,"role":117},"Adalberto Aguilera",{"lat":202,"lon":203},25.77427,-80.19366,{"facility":101,"status":168,"city":194,"state":188,"zip":205,"country":105,"geoPoint":206},"33173",{"lat":202,"lon":203},{"facility":101,"status":8,"city":194,"state":188,"zip":208,"country":105,"contacts":209,"geoPoint":214},"33174",[210,211,212],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":213,"role":117},"Felix Penate",{"lat":202,"lon":203},{"facility":101,"status":168,"city":216,"state":217,"zip":218,"country":105,"geoPoint":219},"Savannah","Georgia","31406",{"lat":220,"lon":221},32.08354,-81.09983,{"facility":101,"status":8,"city":223,"state":224,"zip":225,"country":105,"contacts":226,"geoPoint":231},"Normal","Illinois","61761",[227,228,229],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":230,"role":117},"Dareen Siri",{"lat":232,"lon":233},40.5142,-88.99063,{"facility":101,"status":8,"city":235,"state":236,"zip":237,"country":105,"contacts":238,"geoPoint":243},"Owensboro","Kentucky","42301",[239,240,241],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":242,"role":117},"Lee Clore",{"lat":244,"lon":245},37.77422,-87.11333,{"facility":101,"status":168,"city":247,"state":248,"zip":249,"country":105,"geoPoint":250},"Columbia","Missouri","65203",{"lat":251,"lon":252},38.95171,-92.33407,{"facility":101,"status":8,"city":254,"state":255,"zip":256,"country":105,"contacts":257,"geoPoint":262},"Missoula","Montana","59808",[258,259,260],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":261,"role":117},"Carl Thornblade",{"lat":263,"lon":264},46.87215,-113.994,{"facility":101,"status":8,"city":266,"state":267,"zip":268,"country":105,"contacts":269,"geoPoint":274},"The Bronx","New York","10461",[270,271,272],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":273,"role":117},"Denise Serebrisky",{"lat":275,"lon":276},40.84985,-73.86641,{"facility":101,"status":8,"city":278,"state":279,"zip":280,"country":105,"contacts":281,"geoPoint":286},"Cincinnati","Ohio","45229",[282,283,284],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":285,"role":117},"Theresa Guilbert",{"lat":287,"lon":288},39.12711,-84.51439,{"facility":101,"status":8,"city":290,"state":279,"zip":291,"country":105,"contacts":292,"geoPoint":297},"Cleveland","44106",[293,294,295],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":296,"role":117},"Kristie Ross",{"lat":298,"lon":299},41.4995,-81.69541,{"facility":101,"status":168,"city":301,"state":279,"zip":302,"country":105,"geoPoint":303},"Dayton","45404",{"lat":304,"lon":305},39.75895,-84.19161,{"facility":101,"status":8,"city":307,"state":308,"zip":309,"country":105,"contacts":310,"geoPoint":315},"Oklahoma City","Oklahoma","73120",[311,312,313],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":314,"role":117},"Martha Tarpay",{"lat":316,"lon":317},35.46756,-97.51643,{"facility":101,"status":8,"city":319,"state":320,"zip":321,"country":105,"contacts":322,"geoPoint":327},"Charleston","South Carolina","29420",[323,324,325],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":326,"role":117},"Patricia Gerber",{"lat":328,"lon":329},32.77632,-79.93275,{"facility":101,"status":8,"city":331,"state":332,"zip":333,"country":105,"contacts":334,"geoPoint":339},"Dallas","Texas","75225-6301",[335,336,337],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":338,"role":117},"Barbara Baxter",{"lat":340,"lon":341},32.78306,-96.80667,{"facility":101,"status":8,"city":343,"state":332,"zip":344,"country":105,"contacts":345,"geoPoint":350},"Kerrville","78028",[346,347,348],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":349,"role":117},"Dale Mohar",{"lat":351,"lon":352},30.04743,-99.14032,{"facility":101,"status":168,"city":354,"state":332,"zip":355,"country":105,"geoPoint":356},"Plano","75034",{"lat":357,"lon":358},33.01984,-96.69889,{"facility":101,"status":168,"city":360,"state":332,"zip":361,"country":105,"geoPoint":362},"Waco","76712",{"lat":363,"lon":364},31.54933,-97.14667,{"facility":101,"status":8,"city":366,"zip":367,"country":368,"contacts":369,"geoPoint":374},"Buenos Aires","1122","Argentina",[370,371,372],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":373,"role":117},"Horacio Budani",{"lat":375,"lon":376},-34.61315,-58.37723,{"facility":101,"status":8,"city":366,"zip":378,"country":368,"contacts":379,"geoPoint":384},"1888",[380,381,382],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":383,"role":117},"Andrea Medina",{"lat":375,"lon":376},{"facility":101,"status":8,"city":366,"zip":386,"country":368,"contacts":387,"geoPoint":392},"C1023AAB",[388,389,390],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":391,"role":117},"Abel Esteban Bordon",{"lat":375,"lon":376},{"facility":101,"status":8,"city":366,"zip":394,"country":368,"contacts":395,"geoPoint":400},"C1202",[396,397,398],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":399,"role":117},"Monica Silvia De Gennaro",{"lat":375,"lon":376},{"facility":101,"status":8,"city":366,"zip":402,"country":368,"contacts":403,"geoPoint":408},"C1425BEN",[404,405,406],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":407,"role":117},"Anahi Yanez",{"lat":375,"lon":376},{"facility":101,"status":8,"city":410,"zip":411,"country":368,"contacts":412,"geoPoint":417},"Córdoba","X5000DCE",[413,414,415],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":416,"role":117},"Victor Hugo Cambursano",{"lat":418,"lon":419},-31.40648,-64.18853,{"facility":101,"status":8,"city":421,"zip":422,"country":368,"contacts":423,"geoPoint":428},"Lanus","B1824KAJ",[424,425,426],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":427,"role":117},"Adriana Sosso",{"lat":429,"lon":430},-34.70757,-58.39132,{"facility":101,"status":8,"city":432,"zip":433,"country":368,"contacts":434,"geoPoint":439},"Lobos","7240",[435,436,437],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":438,"role":117},"Fabian Dabove",{"lat":440,"lon":441},-35.18537,-59.09788,{"facility":101,"status":8,"city":443,"zip":444,"country":368,"contacts":445,"geoPoint":450},"Lujan de Cuyo","5509",[446,447,448],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":449,"role":117},"Cristian Fazio",{"lat":451,"lon":452},-33.03917,-68.87955,{"facility":101,"status":8,"city":454,"zip":455,"country":368,"contacts":456,"geoPoint":461},"Mar del Plata","7600",[457,458,459],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":460,"role":117},"Jorge Taborda",{"lat":462,"lon":463},-38.00042,-57.5562,{"facility":101,"status":8,"city":465,"zip":466,"country":368,"contacts":467,"geoPoint":472},"Rosario","2000",[468,469,470],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":471,"role":117},"Adriana Marcipar",{"lat":473,"lon":474},-32.94682,-60.63932,{"facility":101,"status":8,"city":476,"zip":466,"country":368,"contacts":477},"Rosario Provincia de Santa FE",[478,479,480],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":481,"role":117},"Gabriel Gattolin",{"facility":101,"status":8,"city":483,"zip":484,"country":368,"contacts":485,"geoPoint":490},"San Miguel de Tucumán","T4000IHE",[486,487,488],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":489,"role":117},"Ramona Silvia del Valle Orosco Segura",{"lat":491,"lon":492},-26.81601,-65.21051,{"facility":101,"status":8,"city":494,"zip":495,"country":368,"contacts":496,"geoPoint":501},"Santa Fe","3000",[497,498,499],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":500,"role":117},"Martin Edgardo Roberto Maillo",{"lat":502,"lon":503},-31.64881,-60.70868,{"facility":101,"status":8,"city":505,"state":506,"zip":507,"country":508,"contacts":509,"geoPoint":514},"South Brisbane","Queensland","4101","Australia",[510,511,512],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":513,"role":117},"Ajay Kevat",{"lat":515,"lon":516},-27.48034,153.02049,{"facility":101,"status":8,"city":518,"state":519,"zip":520,"country":508,"contacts":521,"geoPoint":526},"North Adelaide","South Australia","5006",[522,523,524],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":525,"role":117},"Andrew Tai",{"lat":527,"lon":528},-34.90733,138.59141,{"facility":101,"status":8,"city":530,"state":531,"zip":532,"country":508,"contacts":533},"Joondalup WA","Western Australia","6027",[534,535,536],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":537,"role":117},"Desiree Silva",{"facility":101,"status":8,"city":539,"zip":540,"country":541,"contacts":542,"geoPoint":547},"Lo Barnechea","7691236","Chile",[543,544,545],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":546,"role":117},"Alberto Vidal Grell",{"lat":548,"lon":549},-33.36071,-70.51244,{"facility":101,"status":8,"city":551,"zip":552,"country":541,"contacts":553,"geoPoint":558},"Santiago","7630000",[554,555,556],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":557,"role":117},"Maria Palomino",{"lat":559,"lon":560},-33.45694,-70.64827,{"facility":101,"status":8,"city":551,"zip":562,"country":541,"contacts":563,"geoPoint":568},"8320000",[564,565,566],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":567,"role":117},"Daniela Valenzuela Venandy",{"lat":559,"lon":560},{"facility":101,"status":8,"city":570,"zip":571,"country":572,"contacts":573,"geoPoint":578},"Ashkelon","7830604","Israel",[574,575,576],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":577,"role":117},"Alina Avenshtein",{"lat":579,"lon":580},31.66926,34.57149,{"facility":101,"status":8,"city":582,"zip":583,"country":572,"contacts":584,"geoPoint":589},"Haifa","3109600",[585,586,587],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":588,"role":117},"Michal Gur",{"lat":590,"lon":591},32.81303,34.99928,{"facility":101,"status":8,"city":582,"zip":593,"country":572,"contacts":594,"geoPoint":599},"3436212",[595,596,597],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":598,"role":117},"Karin Yaacoby-Bianu",{"lat":590,"lon":591},{"facility":101,"status":8,"city":601,"zip":602,"country":572,"contacts":603,"geoPoint":608},"Petah Tikva","49202",[604,605,606],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":607,"role":117},"Meir Mei-Zahav",{"lat":609,"lon":610},32.08707,34.88747,{"facility":101,"status":8,"city":612,"zip":613,"country":614,"contacts":615,"geoPoint":620},"Guadalajara","44100","Mexico",[616,617,618],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":619,"role":117},"Daniel Alejandro Salazar-Quiroz",{"lat":621,"lon":622},20.67738,-103.34749,{"facility":101,"status":8,"city":624,"zip":625,"country":614,"contacts":626,"geoPoint":631},"Monterrey","64460",[627,628,629],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":630,"role":117},"Sandra Gonzalez-Diaz",{"lat":632,"lon":633},25.68435,-100.31721,{"facility":101,"status":8,"city":635,"zip":636,"country":614,"contacts":637,"geoPoint":642},"San Juan del Río","76800",[638,639,640],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":641,"role":117},"Mario Rosas-Navarro",{"lat":643,"lon":644},20.38897,-99.99637,{"facility":101,"status":8,"city":646,"state":647,"zip":648,"country":649,"contacts":650},"Ebdentown","Upper Hutt","5018","New Zealand",[651,652,653],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":654,"role":117},"Tim Humphrey",{"facility":101,"status":8,"city":656,"zip":657,"country":658,"contacts":659},"Cheongju Chungcheongbuk-do","28644","South Korea",[660,661,662],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":663,"role":117},"Youn-Soo Hahn",{"facility":101,"status":168,"city":665,"zip":666,"country":658,"geoPoint":667},"Seoul","03722",{"lat":668,"lon":669},37.566,126.9784,{"facility":101,"status":8,"city":665,"zip":671,"country":658,"contacts":672,"geoPoint":677},"05505",[673,674,675],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":676,"role":117},"Jinho Yu",{"lat":668,"lon":669},{"facility":101,"status":8,"city":665,"zip":679,"country":658,"contacts":680,"geoPoint":685},"2447",[681,682,683],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":684,"role":117},"Ju Kim",{"lat":668,"lon":669},{"facility":101,"status":8,"city":687,"zip":688,"country":689,"contacts":690,"geoPoint":695},"Adana","1173","Turkey (Türkiye)",[691,692,693],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":694,"role":117},"Dilek Ozcan",{"lat":696,"lon":697},36.98615,35.32531,{"facility":101,"status":8,"city":699,"zip":700,"country":689,"contacts":701,"geoPoint":706},"Antalya","07070",[702,703,704],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":705,"role":117},"Aysen Bingol",{"lat":707,"lon":708},36.90812,30.69556,{"facility":101,"status":8,"city":710,"zip":711,"country":689,"contacts":712,"geoPoint":717},"Istanbul","34010",[713,714,715],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":716,"role":117},"Cansin Sackesen",{"lat":718,"lon":719},41.01384,28.94966,{"facility":101,"status":8,"city":710,"zip":721,"country":689,"contacts":722,"geoPoint":727},"34899",[723,724,725],{"name":108,"role":109,"phone":110,"email":111},{"name":113,"role":109,"phone":114,"email":111},{"name":726,"role":117},"Ahmet Ozen",{"lat":718,"lon":719},[729,730],{"name":108,"role":109,"phone":110,"email":111},{"name":731,"role":109,"phone":732,"email":111},"EU GSK Clinical Trials Call Center","+44 (0) 20 89904466",[734],{"name":735,"affiliation":13,"role":736},"GSK Clinical Trials","STUDY_DIRECTOR",[],[],{"nct_id":4,"conditions":740,"biomarkers":741},[19],[],{"nct_id":4,"found":743,"summary":744,"prompt_version":754},true,{"design":745,"status":746,"heading":747,"summary":748,"follow_up":749,"word_count":750,"commitments":751,"compensation":752,"drugs_mentioned":753},"This is an interventional study comparing two different drug treatments for asthma. It plans to enroll 292 participants.","completed","Study of FF\u002FUMEC\u002FVI for Asthma in Adolescents","This study is looking at how well two different asthma medications, FF\u002FUMEC\u002FVI and FF\u002FVI, work in teenagers aged 12 to 17. Both medications are given using an ELLIPTA inhaler. The main goal is to see if FF\u002FUMEC\u002FVI improves lung function more than FF\u002FVI after 24 weeks of treatment. You might be able to join if you are 12-17 years old, have had asthma for at least a year, and currently use daily inhaled corticosteroids (ICS) and long-acting beta2-agonists (LABA). The study aims to enroll 292 participants, but its current status is unclear.","The primary endpoint measures changes in lung function at Week 24.",92,"Not specified in the trial record.","Not stated in the trial record.",[40,46,51],"v2"]