[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT05849025":3,"trial-entities:NCT05849025":82,"trial-summary:NCT05849025":85},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":21,"study_type":22,"primary_purpose":17,"phases":23,"enrollment_info":24,"interventions":27,"primary_outcomes":28,"secondary_outcomes":33,"sex":34,"minimum_age":35,"maximum_age":17,"healthy_volunteers":36,"eligibility_criteria":37,"std_ages":51,"locations":54,"central_contacts":75,"overall_officials":78,"references":80,"see_also_links":81},"NCT05849025","23-001939","A Study of Invasive Hemodynamic for MACHD Registry","Invasive Hemodynamic Control Cohort for The Mayo Clinic Adult Congenital Heart Disease (MACHD) Registry","RECRUITING","2026-12","2026-04","2026-05-05","2023-10-16","Mayo Clinic","OTHER",false,"This research study is being done to provide comparative data to the Mayo Clinic Adult Congenital Heart Disease Registry.",null,[19,20],"Healthy","Congenital Heart Disease",[],"OBSERVATIONAL",[],{"count":25,"type":26},50,"ESTIMATED",[],[29],{"measure":30,"description":31,"timeFrame":32},"Pulmonary vascular reserve","The slope of mean pulmonary artery pressure \u002F cardiac output (mPAP\u002FCO)","Baseline",[],"ALL","18 Years",true,{"inclusion":38,"exclusion":45,"raw_text":50},[39,40,41,42,43,44],"Capacity to Consent","BMI \\\u003C\u002F= 30","Systolic BP \\\u003C\u002F= 140mmHg","Diastolic BP \\\u003C\u002F= 90","eGFR \\> 30 (within prior 3 months) to confirm kidney function","Able to undergo an MRI",[46,47,48,49],"History of Cardiovascular disease that may affect the results of the testing performed.","Any Current orthopedic limitations","Currently taking any cardiac medication","Pregnancy","Inclusion Criteria:\n\n* Capacity to Consent\n* BMI \\\u003C\u002F= 30\n* Systolic BP \\\u003C\u002F= 140mmHg\n* Diastolic BP \\\u003C\u002F= 90\n* eGFR \\> 30 (within prior 3 months) to confirm kidney function\n* Able to undergo an MRI\n\nExclusion Criteria:\n\n* History of Cardiovascular disease that may affect the results of the testing performed.\n* Any Current orthopedic limitations\n* Currently taking any cardiac medication\n* Pregnancy",[52,53],"ADULT","OLDER_ADULT",[55],{"facility":56,"status":8,"city":57,"state":58,"zip":59,"country":60,"contacts":61,"geoPoint":72},"Mayo Clinic Rochester","Rochester","Minnesota","55905","United States",[62,66,70],{"name":63,"role":64,"phone":65},"ACHD Research Program","CONTACT","(507) 293-2565",{"name":67,"role":64,"phone":68,"email":69},"Alexander Egbe, MBBS, MPH","(507) 284-2520","Egbe.Alexander@mayo.edu",{"name":67,"role":71},"PRINCIPAL_INVESTIGATOR",{"lat":73,"lon":74},44.02163,-92.4699,[76,77],{"name":63,"role":64,"phone":65},{"name":67,"role":64,"phone":68,"email":69},[79],{"name":67,"affiliation":13,"role":71},[],[],{"nct_id":4,"conditions":83,"biomarkers":84},[20,19],[],{"nct_id":4,"found":36,"summary":86,"prompt_version":96},{"design":87,"status":88,"heading":89,"summary":90,"follow_up":91,"word_count":92,"commitments":93,"compensation":94,"drugs_mentioned":95},"This is an observational study aiming to enroll 50 participants. It is designed to gather information rather than test a specific treatment.","completed","Observational Study for MACHD Registry","This observational study is looking for 50 healthy adults to help compare information for the Mayo Clinic Adult Congenital Heart Disease (MACHD) Registry. The study is not testing any specific intervention or drug. Instead, it aims to understand pulmonary vascular reserve (how well your lung blood vessels can handle changes in blood flow) at the beginning of the study. You might be able to join if you are 18 or older, have a BMI (Body Mass Index) of 30 or less, healthy blood pressure, good kidney function (eGFR > 30), and can have an MRI. We are currently unsure of the study's recruitment status.","Pulmonary vascular reserve is measured at Baseline, but no further follow-up is specified.",104,"Not specified in the trial record.","Not stated in the trial record.",[],"v2"]