[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT05952999":3,"trial-entities:NCT05952999":154,"trial-summary:NCT05952999":165},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":28,"study_type":32,"primary_purpose":33,"phases":34,"enrollment_info":35,"interventions":38,"primary_outcomes":50,"secondary_outcomes":66,"sex":83,"minimum_age":84,"maximum_age":33,"healthy_volunteers":15,"eligibility_criteria":85,"std_ages":99,"locations":102,"central_contacts":112,"overall_officials":113,"references":117,"see_also_links":153},"NCT05952999","2015255","Analysis of the Virtual Acute Care at Home Experience","Examining the Intervention Effectiveness of Hospital at Home for Improving Health Outcomes and Experiences for Patients, Clinicians, and Caregivers","ENROLLING_BY_INVITATION","2026-12-31","2026-03","2026-03-17","2023-08-15","OSF Healthcare System","OTHER",false,"The purpose of this study is to examine the implementation, intervention effectiveness, and dissemination of a digital acute care delivery model for improving selected health outcomes in the Hospital at Home population.","The investigators will conduct a mixed-methods quasi-experimental research study that will explore the effectiveness of the Hospital at home programs using qualitative interviews and quantitative data as a means to also conduct a process evaluation related to the implementation and efficacy of Hospital at Home programs. The purpose of this pragmatic study is to inform scalability beyond the initial site for implementation within a large healthcare system with a diverse patient population located in various communities, including rural and urban locations.",[19,20,21,22,23,24,25,26,27],"Conditions","Infections","Heart Failure","Renal and Urinary Disorders","Diabetes","Hypertension","Fever","Bronchitis","Asthma, Chronic Obstructive Pulmonary Disease (COPD)",[29,30,31],"home hospital","hospital at home","hospital in the home","OBSERVATIONAL",null,[],{"count":36,"type":37},9654,"ESTIMATED",[39,46],{"type":14,"name":40,"description":41,"armGroupLabels":42,"otherNames":44},"Digital Care Solution as supportive personalized care","Patients will need to meet screening and inclusion criteria at time of enrollment. As a pragmatic study, researchers will not determine criteria or management of care aspects for patients.",[43],"Hospital at Home Care",[45],"Traditional Hospital Level Care",{"type":14,"name":45,"description":47,"armGroupLabels":48},"Patients will be cared for in the inpatient setting for management of diseases that meet screening and inclusion criteria at time of enrollment for hospital at home. As a pragmatic study, researchers will not determine criteria or management of care aspects for patients.",[49],"Traditional Hospital Care",[51,55,59,63],{"measure":52,"description":53,"timeFrame":54},"Composite of all-cause mortality for patients admitted to digital hospital","Total number of deaths over total number of patients admitted to the digital hospital.","Up to 30 days, (date of death from any cause, whichever came first, assessed up to 30 days)",{"measure":56,"description":57,"timeFrame":58},"30-day readmission rate","Number of 30-day readmissions as defined by Organization using preset criteria","Up to 30 days (date of readmission from any cause, whichever came first, assessed up to 30 days)",{"measure":60,"description":61,"timeFrame":62},"Patient Satisfaction at discharge","1-item measure: I would recommend this \\[insert program name\\] to others, assessed at discharge name\\] to others.","up to 1 week",{"measure":64,"description":65,"timeFrame":62},"Patient Perception of Digital Care at discharge","Results of Digital Care - Likert Scale (very satisfied to very dissatisfied)",[67,71,75,79],{"measure":68,"description":69,"timeFrame":70},"Escalations (for management and treatment of early decompensation)","percentage of patients escalated over total hospital digital encounters","up to 2 weeks",{"measure":72,"description":73,"timeFrame":74},"Unplanned readmission within 30-days of discharge","Number of 30-day readmissions over total number of discharges","up to 30 days",{"measure":76,"description":77,"timeFrame":78},"Length of Stay","Day of admission to day of discharge, assessed up to 2 months","assessed up to 2 weeks",{"measure":80,"description":81,"timeFrame":82},"Number of participants with Hospital Acquired Infections","Number of hospital acquired infections reported (CAUTI, CLABSI, etc.)","assessed up to 1 week","ALL","18 Years",{"inclusion":86,"exclusion":95,"raw_text":98},[87,88,89,90,91,92,93,94],"Patients 18 years and older who are admitted into the Hospital at Home program after presenting to the emergency department or who are inpatients that can be cared at home for hospital level needs","Patients meeting the hospital's criteria for admission by diagnosis type (e.g., heart failure, respiratory infections and inflammations, renal failure, diabetes, pneumonia, bronchitis, chronic obstructive pulmonary disease, fever and inflammatory conditions, viral illnesses, other disorders of the nervous system). Diagnoses are determined by clinicians not researchers.","Patients will need to reside within 30 minutes' drive time from the hospital","Age \\>= 18 years old","as capacity to consent to study","Any member of the home hospital clinical team (a healthcare professional who providing care or equipment for use in the home) who will be participating in delivery of healthcare services,","Any member of the hospital care teams, including the screening and recruitment of patients for the home hospital intervention and\u002For providing care to patients that enroll in the intervention that is provided","Any member of the leadership team who are involved in the operational aspects of program delivery",[96,97],"Need for long-term facility level care or current residence in a facility of this type","No one will be excluded on the basis of sex or race","Inclusion Criteria:\n\n* Patients 18 years and older who are admitted into the Hospital at Home program after presenting to the emergency department or who are inpatients that can be cared at home for hospital level needs\n* Patients meeting the hospital's criteria for admission by diagnosis type (e.g., heart failure, respiratory infections and inflammations, renal failure, diabetes, pneumonia, bronchitis, chronic obstructive pulmonary disease, fever and inflammatory conditions, viral illnesses, other disorders of the nervous system). Diagnoses are determined by clinicians not researchers.\n* Patients will need to reside within 30 minutes' drive time from the hospital\n\nPatient caregiver inclusion criteria: (not required for patient participation):\n\n* Age \\>= 18 years old\n* as capacity to consent to study\n\nClinician or stakeholder inclusion criteria:\n\n* Any member of the home hospital clinical team (a healthcare professional who providing care or equipment for use in the home) who will be participating in delivery of healthcare services,\n* Any member of the hospital care teams, including the screening and recruitment of patients for the home hospital intervention and\u002For providing care to patients that enroll in the intervention that is provided\n* Any member of the leadership team who are involved in the operational aspects of program delivery\n\nExclusion Criteria:\n\n* Need for long-term facility level care or current residence in a facility of this type\n* No one will be excluded on the basis of sex or race",[100,101],"ADULT","OLDER_ADULT",[103],{"facility":104,"city":105,"state":106,"zip":107,"country":108,"geoPoint":109},"OSF HealthCare","Peoria","Illinois","61602","United States",{"lat":110,"lon":111},40.69365,-89.58899,[],[114],{"name":115,"affiliation":104,"role":116},"Colleen Klein, PhD, APRN","PRINCIPAL_INVESTIGATOR",[118,122,125,128,131,134,137,140,143,146,149],{"pmid":119,"type":120,"citation":121},"34100939","BACKGROUND","Arsenault-Lapierre G, Henein M, Gaid D, Le Berre M, Gore G, Vedel I. Hospital-at-Home Interventions vs In-Hospital Stay for Patients With Chronic Disease Who Present to the Emergency Department: A Systematic Review and Meta-analysis. JAMA Netw Open. 2021 Jun 1;4(6):e2111568. doi: 10.1001\u002Fjamanetworkopen.2021.11568.",{"pmid":123,"type":120,"citation":124},"30735244","Brody AA, Arbaje AI, DeCherrie LV, Federman AD, Leff B, Siu AL. Starting Up a Hospital at Home Program: Facilitators and Barriers to Implementation. J Am Geriatr Soc. 2019 Mar;67(3):588-595. doi: 10.1111\u002Fjgs.15782. Epub 2019 Feb 8.",{"pmid":126,"type":120,"citation":127},"34363185","Chua CMS, Ko SQ, Lai YF, Lim YW, Shorey S. Perceptions of Hospital-at-Home Among Stakeholders: a Meta-synthesis. J Gen Intern Med. 2022 Feb;37(3):637-650. doi: 10.1007\u002Fs11606-021-07065-0. Epub 2021 Aug 6.",{"pmid":129,"type":120,"citation":130},"34608377","Cooling M, Klein CJ, Pierce LM, Delinski N, Lotz A, Vozenilek JA. Access to Care: End-to-End Digital Response for COVID-19 Care Delivery. J Nurse Pract. 2022 Feb;18(2):232-235. doi: 10.1016\u002Fj.nurpra.2021.09.011. Epub 2021 Sep 25.",{"pmid":132,"type":120,"citation":133},"30948606","Dismore LL, Echevarria C, van Wersch A, Gibson J, Bourke S. What are the positive drivers and potential barriers to implementation of hospital at home selected by low-risk DECAF score in the UK: a qualitative study embedded within a randomised controlled trial. BMJ Open. 2019 Apr 4;9(4):e026609. doi: 10.1136\u002Fbmjopen-2018-026609.",{"pmid":135,"type":120,"citation":136},"29946693","Federman AD, Soones T, DeCherrie LV, Leff B, Siu AL. Association of a Bundled Hospital-at-Home and 30-Day Postacute Transitional Care Program With Clinical Outcomes and Patient Experiences. JAMA Intern Med. 2018 Aug 1;178(8):1033-1040. doi: 10.1001\u002Fjamainternmed.2018.2562.",{"pmid":138,"type":120,"citation":139},"16330791","Leff B, Burton L, Mader SL, Naughton B, Burl J, Inouye SK, Greenough WB 3rd, Guido S, Langston C, Frick KD, Steinwachs D, Burton JR. Hospital at home: feasibility and outcomes of a program to provide hospital-level care at home for acutely ill older patients. Ann Intern Med. 2005 Dec 6;143(11):798-808. doi: 10.7326\u002F0003-4819-143-11-200512060-00008.",{"pmid":141,"type":120,"citation":142},"21135026","Savundranayagam MY, Montgomery RJ, Kosloski K. A dimensional analysis of caregiver burden among spouses and adult children. Gerontologist. 2011 Jun;51(3):321-31. doi: 10.1093\u002Fgeront\u002Fgnq102. Epub 2010 Dec 6.",{"pmid":144,"type":120,"citation":145},"32478025","Shelton RC, Chambers DA, Glasgow RE. An Extension of RE-AIM to Enhance Sustainability: Addressing Dynamic Context and Promoting Health Equity Over Time. Front Public Health. 2020 May 12;8:134. doi: 10.3389\u002Ffpubh.2020.00134. eCollection 2020.",{"pmid":147,"type":120,"citation":148},"35710450","Yao X, Paulson M, Maniaci MJ, Dunn AN, Nelson CR, Behnken EM, Hart MS, Sangaralingham LR, Inselman SA, Lampman MA, Dunlay SM, Dowdy SC, Habermann EB. Effect of hospital-at-home vs. traditional brick-and-mortar hospital care in acutely ill adults: study protocol for a pragmatic randomized controlled trial. Trials. 2022 Jun 16;23(1):503. doi: 10.1186\u002Fs13063-022-06430-6.",{"pmid":150,"type":151,"citation":152},"40464036","DERIVED","Dalstrom MD, Klein CJ, Rothrock-Magana M, Cooling M. Patient-Centered Care: A Qualitative Analysis of Patient and Caregiver Experiences in a Hospital at Home Program. J Patient Exp. 2025 Jun 2;12:23743735251347706. doi: 10.1177\u002F23743735251347706. eCollection 2025.",[],{"nct_id":4,"conditions":155,"biomarkers":164},[26,156,157,25,21,158,159,160,161,162,163],"Chronic Obstructive Pulmonary Disease","Diabetes Mellitus","Inflammatory colitis","Nervous System Disorder","Pneumonia","Renal Failure","Respiratory tract infection","Viral Infection",[],{"nct_id":4,"found":15,"summary":33,"prompt_version":33}]