[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT06083324":3,"trial-entities:NCT06083324":102,"trial-summary:NCT06083324":106},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":20,"study_type":23,"primary_purpose":17,"phases":24,"enrollment_info":25,"interventions":28,"primary_outcomes":38,"secondary_outcomes":48,"sex":60,"minimum_age":61,"maximum_age":62,"healthy_volunteers":63,"eligibility_criteria":64,"std_ages":68,"locations":71,"central_contacts":90,"overall_officials":95,"references":96,"see_also_links":101},"NCT06083324","2023-021-SG","EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer","EXERT-C: Prospective Study of an EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer","RECRUITING","2028-01-16","2026-07","2026-07-08","2023-02-03","Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)","OTHER",true,"This protocol seeks to analyze patient outcomes of the standard of care, monitored group exercise regimen of high-load resistance training and functional exercises with compound movements under close supervision on individuals who have been treated for cancer.",null,[19],"Cancer",[21,22],"exercise","resistance training","OBSERVATIONAL",[],{"count":26,"type":27},100,"ESTIMATED",[29],{"type":14,"name":30,"description":31,"armGroupLabels":32},"Dose escalated resistance training","All individuals will be engaging in resistance training during and\u002For after their cancer treatment",[33,34,35,36,37],"Colorectal cancer patients","General cancer patients","Head and neck cancer patients","Metastatic breast cancer patients","Pancreatic cancer patients",[39,43,46],{"measure":40,"description":41,"timeFrame":42},"Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via bioimpedance analysis","Measurement on bioimpedance analysis machine (Inbody 970)","3 months",{"measure":44,"description":45,"timeFrame":42},"Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via ultrasound","Measurement via ultrasound and calculation with Jackson-Pollack calculations",{"measure":47,"description":41,"timeFrame":42},"Determine changes in muscle mass in pounds from before to after the nutrition and exercise regimen",[49,51,54,57],{"measure":50,"description":50,"timeFrame":42},"Determine changes in overall score of functional movement screen (FMS) from before to after the nutrition and exercise regimen",{"measure":52,"description":53,"timeFrame":42},"Determine changes in Y-balance score for each leg","Y-balance score adds up the distance each leg can move in the front and side directions, divided by the length of the hip. This correlates inversely with fall risk.",{"measure":55,"description":56,"timeFrame":42},"Determine changes in strength via load measured in pounds from before to after the nutrition and exercise regimen","Load is calculated by multiplying sets by repetitions by weight lifted for a specific exercise",{"measure":58,"description":59,"timeFrame":42},"Determine changes in EQ-5D responses 1-5 and overall score from before to after the nutrition and exercise regimen","EQ-5D asks 5 questions rates from 1-5 and an overall rating of health","ALL","20 Years","89 Years",false,{"inclusion":65,"exclusion":66,"raw_text":67},[],[],"Inclusion Criteria:\n\n1. Age 20-89 years\n2. Women of child-bearing potential must verbally confirm lack of pregnancy prior to enrollment. They should also consent to use adequate contraception during the course of the study.\n3. Participants must be determined capable of engaging in resistance training by exercise personnel and\u002For study PI\n4. Participants must complete an assessment by EOC staff and be determined safe to engage in the workout regimen by the study exercise personnel.\n5. Individuals not deemed safe to participate in the standard EOC exercise program will be referred to physical therapy or elsewhere\n\nExclusion Criteria:\n\n1\\. Severe arthritic, joint, cardiovascular, or musculoskeletal condition that would interfere with exercise program",[69,70],"ADULT","OLDER_ADULT",[72],{"facility":73,"status":8,"city":74,"state":75,"zip":76,"country":77,"contacts":78,"geoPoint":87},"AHN CI Exercise Oncology and Resiliency Center","Pittsburgh","Pennsylvania","15202","United States",[79,84],{"name":80,"role":81,"phone":82,"email":83},"Colin E Champ, MD, CSCS","CONTACT","412-734-7605","colin.champ@ahn.org",{"name":85,"role":86},"Chris Peluso, BS","SUB_INVESTIGATOR",{"lat":88,"lon":89},40.44062,-79.99589,[91],{"name":92,"role":81,"phone":93,"email":94},"Samantha Campbell","(412) 330-6151","samantha.campbell@ahn.org",[],[97],{"pmid":98,"type":99,"citation":100},"36175646","BACKGROUND","Champ CE, Carpenter DJ, Diaz AK, Rosenberg J, Ackerson BG, Hyde PN. Resistance Training for Patients with Cancer: A Conceptual Framework for Maximizing Strength, Power, Functional Mobility, and Body Composition to Optimize Health and Outcomes. Sports Med. 2023 Jan;53(1):75-89. doi: 10.1007\u002Fs40279-022-01759-z. Epub 2022 Sep 29.",[],{"nct_id":4,"conditions":103,"biomarkers":105},[104],"Malignant Neoplasm",[],{"nct_id":4,"found":15,"summary":107,"prompt_version":117},{"design":108,"status":109,"heading":110,"summary":111,"follow_up":112,"word_count":113,"commitments":114,"compensation":115,"drugs_mentioned":116},"This is an observational study, meaning researchers will watch and record outcomes from a standard exercise program. It plans to include 100 participants.","completed","Exercise Regimen After Cancer Treatment","This study is looking at how a supervised exercise program, called dose escalated resistance training, affects people who have been treated for cancer. You might be able to join if you are between 20 and 89 years old and are able to do resistance training. The study wants to see if this exercise program can change your body composition, specifically looking at how much fat and muscle you have. Researchers will measure these changes using bioimpedance analysis and ultrasound after 3 months. The study plans to enroll 100 participants, but its current status is unclear.","Measurements for changes in fat and muscle mass will be taken at 3 months after the regimen.",95,"You will engage in resistance training during and\u002For after your cancer treatment. Your fat and muscle mass will be measured at 3 months.","Not stated in the trial record.",[30],"v2"]