[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT06128928":3,"trial-entities:NCT06128928":103,"trial-summary:NCT06128928":107},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":21,"study_type":26,"primary_purpose":27,"phases":28,"enrollment_info":30,"interventions":33,"primary_outcomes":45,"secondary_outcomes":50,"sex":51,"minimum_age":52,"maximum_age":53,"healthy_volunteers":54,"eligibility_criteria":55,"std_ages":68,"locations":71,"central_contacts":92,"overall_officials":96,"references":101,"see_also_links":102},"NCT06128928","IRB00345930","Connecting Friends and Health Workers to Boost COVID-19 Vaccination in Latino Communities","REDES: a Peer Network and mHealth Community Health Worker (CHW) Model to Improve COVID-19 Vaccination Among Latinos","RECRUITING","2026-12-31","2025-11","2025-11-12","2023-07-08","Johns Hopkins University","OTHER",false,"The goal of this clinical trial is to find out which approach works better in getting more of the friends and connections of Latino adults get vaccinated against COVID-19.\n\nThe main questions this study aims to answer are:\n\n1. Can teaching people to use motivational interviewing help more friends and connections of Latino adults get the COVID-19 vaccine compared to just giving information about the vaccine?\n2. What are the things that make it easier or harder for Latinos and networks to get the COVID-19 vaccine?\n3. How does this intervention work in practice so that it can be made available to more people in the future\n\nThe researchers will compare the vaccine rates of the friends and connections of Latinos who have been trained in motivational interviewing with those who have only been given information about the COVID-19 vaccine. This will help figure out which method works best to encourage more people to get vaccinated.","This study will test the efficacy of an intervention REDES (\"Networks\") - a social network intervention - to address COVID-19 vaccine hesitancy and uptake among a cohort of Latinos and networks. 300 index participants who have taken the COVID-19 vaccine will be recruited. Half of the index participants (n=150) will be randomized to the experimental group and will receive training on motivational interviewing to promote vaccine acceptance and uptake with networks. Index participants in the control group (n=150) will receive updated information about the COVID-19 vaccine. In addition, unvaccinated primary and secondary network members of indexes will be recruited for study participation and COVID-19 vaccination. All participants will be followed prospectively at 6, 12, and 18 months after baseline intake. The specific aims are: 1) Evaluate the efficacy of the REDES intervention to promote COVID-19 vaccine uptake among Latinos; 2) Examine ongoing barriers and facilitators of vaccine uptake among Latinos and networks to tailor the intervention and address new challenges, and 3) Evaluate the implementation determinants and outcomes of REDES to inform future broad-scale implementation.",[19,20],"COVID-19","Vaccine",[22,23,24,25],"COVID-19 vaccine uptake","Latino","vaccine hesitancy","Network referrals","INTERVENTIONAL","PREVENTION",[29],"NA",{"count":31,"type":32},900,"ESTIMATED",[34,40],{"type":35,"name":36,"description":37,"armGroupLabels":38},"BEHAVIORAL","REDES","Training on motivational interviewing (MI) led by community health workers on how to use MI to address vaccine hesitancy using a guiding approach, open-ended questions, affirmations, reflections, and summaries.",[39],"REDES: Motivational interviewing training",{"type":35,"name":41,"description":42,"armGroupLabels":43},"Control","Brief CHW-led training about the safety and efficacy of the COVID-19 vaccine. Participants will have the opportunity to ask clarifying questions from the CHWs during the training.",[44],"Control: COVID-19 vaccine information",[46],{"measure":47,"description":48,"timeFrame":49},"COVID-19 vaccine status among networks","Number of network participants who receive the COVID-19 vaccine","Up to 18 months",[],"ALL","18 Years",null,true,{"inclusion":56,"exclusion":64,"raw_text":67},[57,58,59,60,61,58,59,62,63],"Age 18 years or older, and","Self-identifies as Hispanic\u002FLatino, and","Living in Maryland, and","Has received at least one COVID-19 vaccine\u002Fbooster in the last 12 months.","18 years old or older, and","Provide a study coupon to verify that they were referred by an index or a primary network member, and","Has not received at least one COVID-19 vaccine\u002Fbooster in the last 12 months.",[65,66],"Previously participated in the study","Lacks capacity to consent","Inclusion Criteria:\n\nEligibility criteria for index participants (eligibility for index participants is intended to select participants who are less vaccine hesitant):\n\n* Age 18 years or older, and\n* Self-identifies as Hispanic\u002FLatino, and\n* Living in Maryland, and\n* Has received at least one COVID-19 vaccine\u002Fbooster in the last 12 months.\n\nEligibility criteria for primary and secondary network members (peers):\n\nEligibility for peers is intended to select for participants who are more vaccine hesitant (e.g. unvaccinated, or have not received at least one COVID-19 vaccine\u002Fbooster in the last 12 months)\n\n* 18 years old or older, and\n* Self-identifies as Hispanic\u002FLatino, and\n* Living in Maryland, and\n* Provide a study coupon to verify that they were referred by an index or a primary network member, and\n* Has not received at least one COVID-19 vaccine\u002Fbooster in the last 12 months.\n\nExclusion Criteria:\n\n* Previously participated in the study\n* Lacks capacity to consent",[69,70],"ADULT","OLDER_ADULT",[72],{"facility":13,"status":8,"city":73,"state":74,"zip":75,"country":76,"contacts":77,"geoPoint":89},"Baltimore","Maryland","21287","United States",[78,83,87],{"name":79,"role":80,"phone":81,"email":82},"Kathleen Page, MD","CONTACT","410-321-0909","kpage2@jhmi.edu",{"name":84,"role":80,"phone":85,"email":86},"Adrianna Moore, MSW","(410) 321-0909","adrianna.moore@jhmi.edu",{"name":79,"role":88},"PRINCIPAL_INVESTIGATOR",{"lat":90,"lon":91},39.29038,-76.61219,[93,95],{"name":94,"role":80,"phone":85,"email":82},"Kathleen R Page, MD",{"name":84,"role":80,"phone":81,"email":86},[97,98],{"name":94,"affiliation":13,"role":88},{"name":99,"affiliation":100,"role":88},"Cui Yang, PhD","Rutgers University",[],[],{"nct_id":4,"conditions":104,"biomarkers":106},[105],"COVID-19 Infection",[],{"nct_id":4,"found":54,"summary":108,"prompt_version":116},{"design":109,"status":110,"heading":6,"summary":111,"follow_up":109,"word_count":112,"commitments":113,"compensation":114,"drugs_mentioned":115},"Not specified.","completed","{\n   \"Boosting COVID-19 Vaccination in Latino Communities\",\n   \"This study, called REDES, is looking at the best ways to encourage COVID-19 vaccination within Latino communities. It compares two approaches: one where participants learn \\\"motivational interviewing\\\" (a way to help others make their own health decisions) to discuss vaccines with their friends and family, and another where participants receive information about vaccine safety and effectiveness. The goal is to see if teaching motivational interviewing helps more friends and connections of Latino adults get vaccinated. To join, you must be 18 or older, identify as Hispanic\u002FLatino, live in Maryland, and have received at least one COVID-19 vaccine\u002Fbooster in the last 12 months. The study will track vaccination rates among participants' networks for up to 18 months to see which method is more effective.\",\n  \"design\": \"This is an interventional study planning to enroll 900 participants. It compares two behavioral interventions: REDES (motivational interviewing training) and a control group (brief vaccine information).\",\n  \"commitments\": \"Participants will receive training on either motivational interviewing or COVID-19 vaccine information. Unvaccinated friends and family members of participants will also be recruited. All participants will be followed at 6, 12, and 18 months after starting the study.\",\n  \"compensation\": \"Not stated in the trial record.\",\n  \"follow_up\": \"Participants will be followed for up to 18 months after their initial enrollment.\",\n}",218,"Not specified in the trial record.","Not stated in the trial record.",[36,41],"v2"]