[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT06267339":3,"trial-entities:NCT06267339":98,"trial-summary:NCT06267339":102},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":16,"conditions":17,"keywords":19,"study_type":25,"primary_purpose":26,"phases":27,"enrollment_info":29,"interventions":32,"primary_outcomes":44,"secondary_outcomes":52,"sex":59,"minimum_age":60,"maximum_age":61,"healthy_volunteers":62,"eligibility_criteria":63,"std_ages":71,"locations":73,"central_contacts":83,"overall_officials":93,"references":96,"see_also_links":97},"NCT06267339","TD_tRNS","Effects of Transcranial Random Noise Stimulation on Motor Learning in Typically Developing Adolescents","UNKNOWN","2026-08-31","2024-02","2024-02-20","2024-09-01","Burke Medical Research Institute","OTHER",false,"The goal of this study is to compare motor learning rates on two different tasks, when combined with non-invasive brain stimulation.","We will apply transcranial random noise stimulation or sham stimulation. During tRNS, participants will complete a grasping task or a reaching task. Each participant will complete both tasks, with a wait period between each task. Task order will be randomized, such that half the group will begin with each task. We will compare task scored before vs. after tRNS, for each task. This will be a measure of motor learning.",[18],"Children",[20,21,22,23,24],"typically developing children","motor learning","controls","grasp","reach","INTERVENTIONAL","BASIC_SCIENCE",[28],"EARLY_PHASE1",{"count":30,"type":31},40,"ESTIMATED",[33,40],{"type":34,"name":35,"description":36,"armGroupLabels":37},"DEVICE","transcranial random noise stimulation","This intervention will give children tRNS during reaching or grasping repetitive movements.",[38,39],"Grasp Task","Reach Task",{"type":34,"name":41,"description":42,"armGroupLabels":43},"Sham stimulation","This intervention will give children sham stimulation during reaching or grasping repetitive movements.",[38,39],[45,49],{"measure":46,"description":47,"timeFrame":48},"Change in Grasp score","Participants will be asked to perform a grasping task, scored by number of pegs placed in a board.","Immediately before vs. Immediately after brain stimulation",{"measure":50,"description":51,"timeFrame":48},"Change in Reach score","Participants will be asked to perform a reaching task to stack cups, scored by time taken to stack all cups.",[53,56],{"measure":54,"description":55,"timeFrame":48},"Change in Graded Redefined Assessment of Strength, Prehension assessment (GRASSP)","Participants will be asked to perform the GRASSP, scored by tallying points according to the test parametrics.",{"measure":57,"description":58,"timeFrame":48},"Change in score on second reaching task","Participants will be asked to perform a reaching task to stack cups in a different pattern from Primary Outcome #2, scored by time taken to stack all cups.","ALL","10 Years","17 Years",true,{"inclusion":64,"exclusion":68,"raw_text":70},[65,66,67],"Age 10-17 years","Ability to follow two-step instructions","Provides informed consent",[69],"Presence of illness, disease","Inclusion Criteria:\n\n* Age 10-17 years\n* Ability to follow two-step instructions\n* Provides informed consent\n\nExclusion Criteria:\n\n* Presence of illness, disease",[72],"CHILD",[74],{"facility":75,"city":76,"state":77,"zip":78,"country":79,"geoPoint":80},"Burke Neurological Institute","White Plains","New York","10605","United States",{"lat":81,"lon":82},41.03399,-73.76291,[84,89],{"name":85,"role":86,"phone":87,"email":88},"Kathleen Friel, PhD","CONTACT","19143683116","kaf3001@med.cornell.edu",{"name":90,"role":86,"phone":91,"email":92},"Shivakeshavan Ratnadurai-Giriharan, PhD","191436383160","shr3006@med.cornell.edu",[94],{"name":85,"affiliation":75,"role":95},"PRINCIPAL_INVESTIGATOR",[],[],{"nct_id":4,"conditions":99,"biomarkers":101},[100],"Healthy Volunteers",[],{"nct_id":4,"found":62,"summary":103,"prompt_version":113},{"design":104,"status":105,"heading":106,"summary":107,"follow_up":108,"word_count":109,"commitments":110,"compensation":111,"drugs_mentioned":112},"This interventional study plans to enroll 40 participants. It compares two interventions: transcranial random noise stimulation and sham stimulation.","completed","Transcranial Random Noise Stimulation for Motor Learning in Adolescents","This study is looking at how a type of non-invasive brain stimulation, called transcranial random noise stimulation (tRNS), affects motor learning in adolescents. Researchers want to see if tRNS can help improve how quickly young people learn new movements, like reaching or grasping. You might be able to join if you are between 10 and 17 years old, can follow simple instructions, and do not have any illnesses or diseases. The study will compare your grasping and reaching scores before and after receiving either tRNS or a sham stimulation (a fake stimulation that feels similar but has no effect). The goal is to see if tRNS leads to better motor learning compared to the sham stimulation. The current recruitment status is unclear.","Your grasp and reach scores will be measured immediately before and immediately after brain stimulation.",122,"You will complete a grasping task and a reaching task, with a waiting period between them. During these tasks, you will receive either transcranial random noise stimulation or sham stimulation.","Not stated in the trial record.",[35,41],"v2"]