[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT06315595":3,"trial-entities:NCT06315595":85,"trial-summary:NCT06315595":89},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":16,"conditions":17,"keywords":19,"study_type":20,"primary_purpose":14,"phases":21,"enrollment_info":22,"interventions":25,"primary_outcomes":31,"secondary_outcomes":36,"sex":37,"minimum_age":38,"maximum_age":14,"healthy_volunteers":39,"eligibility_criteria":40,"std_ages":45,"locations":48,"central_contacts":75,"overall_officials":78,"references":80,"see_also_links":81},"NCT06315595","15-003511","Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion and Non-Contrast MRI","RECRUITING","2030-09-30","2026-04","2026-04-17","2015-09-30","Mayo Clinic","OTHER",null,"This study evaluates if technical improvements in MRI can be used to provide improved performance contrast-enhanced MRI as used for angiography and perfusion as well as in non-contrast MRI.","PRIMARY OBJECTIVE:\n\nI. To study how a variety of technological approaches in MRI can be used to provide improved performance contrast-enhanced MR imaging as used for angiography and perfusion as well as in MR image acquisition without the use of contrast material.\n\nOUTLINE: This is an observational study.\n\nParticipants undergo a non-contrast MRI on study and may optionally undergo a second non-contrast MRI on study. Participants may also undergo blood sample collection on study.",[18],"Prostate Neoplasm",[],"OBSERVATIONAL",[],{"count":23,"type":24},1000,"ESTIMATED",[26],{"type":13,"name":27,"description":28,"armGroupLabels":29},"Non-Interventional Study","Non-interventional study",[30],"Observational",[32],{"measure":33,"description":34,"timeFrame":35},"Improved performance in contrast-enhanced magnetic resonance imaging (MRI) as used for angiography and perfusion","Assessed by comparison of two images made from the raw data set but reconstructed using the standard vs. an alternative algorithm (to be determined during study). Data will be tabulated and analyzed statistically.","Baseline (at enrollment); possible second scan at a later date",[],"ALL","18 Years",true,{"inclusion":41,"exclusion":43,"raw_text":44},[42],"Adults",[],"Inclusion Criteria:\n\n* Adults\n\nExclusion Criteria:\n\n* Standard exclusion criteria for clinical MRI; e.g. cardiac pacemaker, claustrophobia, an implanted device that has been determined to be MR conditional at 1.5T but not at 3T, anticipated considerable susceptibility artifact from hip prosthesis, etc.",[46,47],"ADULT","OLDER_ADULT",[49,59],{"facility":50,"status":51,"city":52,"state":53,"zip":54,"country":55,"geoPoint":56},"Mayo Clinic in Arizona","ACTIVE_NOT_RECRUITING","Scottsdale","Arizona","85259","United States",{"lat":57,"lon":58},33.50921,-111.89903,{"facility":60,"status":7,"city":61,"state":62,"zip":63,"country":55,"contacts":64,"geoPoint":72},"Mayo Clinic in Rochester","Rochester","Minnesota","55905",[65,69],{"name":66,"role":67,"phone":68},"Clinical Trials Referral Office","CONTACT","855-776-0015",{"name":70,"role":71},"Stephen J. Riederer, PhD","PRINCIPAL_INVESTIGATOR",{"lat":73,"lon":74},44.02163,-92.4699,[76],{"name":66,"role":67,"phone":68,"email":77},"mayocliniccancerstudies@mayo.edu",[79],{"name":70,"affiliation":60,"role":71},[],[82],{"label":83,"url":84},"Mayo Clinic Clinical Trials","https:\u002F\u002Fwww.mayo.edu\u002Fresearch\u002Fclinical-trials",{"nct_id":4,"conditions":86,"biomarkers":88},[87],"Prostate Carcinoma",[],{"nct_id":4,"found":39,"summary":90,"prompt_version":14},{"design":91,"status":92,"heading":93,"summary":94,"follow_up":95,"word_count":96,"commitments":97,"compensation":98,"drugs_mentioned":99},"This is an observational study, meaning researchers will observe participants without giving them a specific treatment. It aims to include about 1000 participants.","completed","Observational Study of Improved MRI Techniques for Prostate Neoplasm","This observational study is looking at ways to make magnetic resonance imaging (MRI) better for people with prostate neoplasm (abnormal growth of cells in the prostate). Researchers are testing new technical approaches to improve how MRI scans show blood vessels (angiography) and blood flow (perfusion), both with and without using a contrast dye. The goal is to see if these improvements can lead to clearer and more useful MRI images. You might be able to join if you are an adult. The study plans to enroll about 1000 participants. The main way they'll measure success is by looking at how well the improved MRI techniques perform at the start of the study, with a possible second scan later on.","Improved performance in contrast-enhanced MRI is measured at the beginning of the study, with a possible second scan at a later date.",119,"You would undergo a non-contrast MRI scan and might have a second non-contrast MRI scan later. You may also be asked to provide blood samples.","Not stated in the trial record.",[]]