[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT06751927":3,"trial-entities:NCT06751927":93,"trial-summary:NCT06751927":96},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":20,"study_type":21,"primary_purpose":22,"phases":23,"enrollment_info":25,"interventions":28,"primary_outcomes":35,"secondary_outcomes":47,"sex":48,"minimum_age":49,"maximum_age":50,"healthy_volunteers":51,"eligibility_criteria":52,"std_ages":64,"locations":67,"central_contacts":85,"overall_officials":88,"references":91,"see_also_links":92},"NCT06751927","IRB24-1204","New Strategies to Enhance Smoking Cessation","Uptake of Varenicline and Strategies for Enhanced Engagement in Treatment for Smoking Cessation","RECRUITING","2030-12","2025-06","2025-06-11","2025-04-24","University of Chicago","OTHER",false,"The study goal is to get feedback on ways researchers can communicate complex research findings on smoking cessation to better inform patients' decisions to use medication and\u002For quit smoking. This will help researchers and clinicians to provide effective, easy-to-implement treatments designed to address tobacco-related health disparities in Black and other racial\u002Fethnic subgroups. It will also help improve health literacy to change misperceptions and mistrust on uptake of varenicline and other medication for quitting smoking. A professionally made video will explain research findings relevant for varenicline's mechanisms and outcomes relative to other treatment options.\n\nThere are 2 parts to this study:\n\n* Part 1: Focus Group to help develop the educational tool intervention\n* Part 2: Randomized portion of study. In this part of the study, participants will be randomized (like flip of coin) to take part in receive the experimental educational intervention or usual methods to help stop smoking. Participants in either arm can choose to receive varenicline and it will be provided as part of study.",null,[19],"Smoking Cessation",[],"INTERVENTIONAL","PREVENTION",[24],"NA",{"count":26,"type":27},94,"ESTIMATED",[29],{"type":30,"name":31,"description":32,"armGroupLabels":33},"BEHAVIORAL","Educational Video","Education video on smoking, nicotine receptor involvement in addiction, craving, withdrawal and mechanisms of action for nicotine replacement and varenicline.",[34],"Educational Intervention",[36,40,43],{"measure":37,"description":38,"timeFrame":39},"Acceptability of the experimental video intervention","This will be assessed using a modified version of the Client Satisfaction Questionnaire which assesses items such as quality, effectiveness, and intrusiveness on the 10-point Likert scale (0=not at all, 10=very much).","24 weeks",{"measure":41,"description":42,"timeFrame":39},"Determine whether provision of technology access and support will improve program attendance and smoking outcomes","This will be assessed using a modified version of the Client Satisfaction Questionnaire specific to technology component which assesses items such as quality, effectiveness, and intrusiveness on the 10-point Likert scale (0=not at all, 10=very much).",{"measure":44,"description":45,"timeFrame":46},"Trial feasibility","ability to enroll and follow-up with the planned number of participants within the specified time frame.","End of study recruitment (6 months)",[],"ALL","18 Years","75 Years",true,{"inclusion":53,"exclusion":58,"raw_text":63},[54,55,56,57],"Patients must smoke at least 10 cigarettes\u002Fday and do not currently use a smoking cessation medication.","Ages 18-75.","Agree to complete surveys and measures within study.","Ability to understand English and the willingness to sign a written informed consent document.",[59,60,61,62],"Patients who are receiving any other smoking cessation medications.","Patients who are pregnant and\u002For lactating.","Patients with psychiatric contraindications that can prevent adherence to protocol or use of intervention tools in study. For inclusivity on trial, psychiatric contraindications and ability for patient to participate in trial will be assessed on an individual basis by study investigator.","Patients who have a contraindication with varenicline.","Inclusion Criteria:\n\n* Patients must smoke at least 10 cigarettes\u002Fday and do not currently use a smoking cessation medication.\n* Ages 18-75.\n* Agree to complete surveys and measures within study.\n* Ability to understand English and the willingness to sign a written informed consent document.\n\nExclusion Criteria:\n\n* Patients who are receiving any other smoking cessation medications.\n* Patients who are pregnant and\u002For lactating.\n* Patients with psychiatric contraindications that can prevent adherence to protocol or use of intervention tools in study. For inclusivity on trial, psychiatric contraindications and ability for patient to participate in trial will be assessed on an individual basis by study investigator.\n* Patients who have a contraindication with varenicline.",[65,66],"ADULT","OLDER_ADULT",[68],{"facility":13,"status":8,"city":69,"state":70,"zip":71,"country":72,"contacts":73,"geoPoint":82},"Chicago","Illinois","60637","United States",[74,79],{"name":75,"role":76,"phone":77,"email":78},"Clinical Trials Intake","CONTACT","855-702-8222","cancerclinicaltrials@bsd.uchicago.edu",{"name":80,"role":81},"Andrea King","PRINCIPAL_INVESTIGATOR",{"lat":83,"lon":84},41.85003,-87.65005,[86],{"name":75,"role":76,"phone":87,"email":78},"1-855-702-8222",[89],{"name":90,"affiliation":13,"role":81},"Andrea C. King",[],[],{"nct_id":4,"conditions":94,"biomarkers":95},[19],[],{"nct_id":4,"found":51,"summary":97,"prompt_version":106},{"design":98,"status":99,"heading":6,"summary":100,"follow_up":101,"word_count":102,"commitments":103,"compensation":104,"drugs_mentioned":105},"This interventional study plans to enroll 94 participants. It is testing an educational video intervention.","completed","This study is testing a new educational video designed to help people quit smoking. The video explains how nicotine affects the brain and how medications like varenicline (Chantix) and nicotine replacement therapies work. Researchers want to understand if this video, along with technology support, can help people attend smoking cessation programs and successfully quit. You might be able to join if you are 18-75 years old, smoke at least 10 cigarettes a day, and are not currently using other smoking cessation medications. The study will measure how well people like the video and if it helps them quit smoking over 24 weeks. The current recruitment status is unclear.","Participants will be followed for 24 weeks to assess the video's acceptability and smoking outcomes.",108,"You would need to agree to complete surveys and measures within the study. The study will measure outcomes at 24 weeks.","Not stated in the trial record.",[31],"v2"]