[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT06910228":3,"trial-entities:NCT06910228":71,"trial-summary:NCT06910228":75},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":16,"conditions":17,"keywords":19,"study_type":20,"primary_purpose":16,"phases":21,"enrollment_info":22,"interventions":25,"primary_outcomes":30,"secondary_outcomes":39,"sex":40,"minimum_age":41,"maximum_age":42,"healthy_volunteers":14,"eligibility_criteria":43,"std_ages":51,"locations":54,"central_contacts":64,"overall_officials":65,"references":69,"see_also_links":70},"NCT06910228","STUDY00004900","Changes in Cerebral Oxygenation Related to Intraoperative Position Changes","ENROLLING_BY_INVITATION","2026-12","2025-10","2025-10-27","2025-09-08","Joseph D. Tobias","OTHER",false,"This is a prospective, observational study. This study will assess the effect of temporary changes in body position (supine, head of bed elevated 30 degrees, head of bed elevated 60 degrees) in anesthetized patients. Tissue oxygenation will be assessed non-invasively using near infrared spectroscopy (NIRS) by a device that is used in our operating rooms and the ICU setting to assess cerebral and tissue oxygenation.",null,[18],"Scoliosis Patients",[],"OBSERVATIONAL",[],{"count":23,"type":24},50,"ESTIMATED",[26],{"type":27,"name":28,"description":29},"DEVICE","Near infrared spectroscopy (NIRS)","A non-invasive technique that uses light to assess brain function and tissue oxygenation.",[31,35],{"measure":32,"description":33,"timeFrame":34},"Change in cerebral oxygenation at 30 degrees","Moving the head of the bed to 30 degrees and comparing cerebral oxygen levels to levels when patient was lying flat.","5-10 minutes after start of study",{"measure":36,"description":37,"timeFrame":38},"Change in cerebral oxygenation at 60 degrees","Moving the head of the bed to 60 degrees and comparing cerebral oxygen levels to levels when patient was lying flat.","10-15 minutes after start of study",[],"ALL","10 Years","21 Years",{"inclusion":44,"exclusion":46,"raw_text":50},[45],"Patients 10-21 years of age undergoing posterior spinal fusion, requiring neurophysiologic monitoring and an arterial cannula",[47,48,49],"Patients in whom an arterial cannula is not indicated for the surgical procedure","Patients with comorbid conditions that may impact cerebral blood flow, cerebral perfusion or place them at risk for cerebral hypoperfusion","Patients in whom an invasive arterial cannula cannot be placed","Inclusion Criteria:\n\n* Patients 10-21 years of age undergoing posterior spinal fusion, requiring neurophysiologic monitoring and an arterial cannula\n\nExclusion Criteria:\n\n* Patients in whom an arterial cannula is not indicated for the surgical procedure\n* Patients with comorbid conditions that may impact cerebral blood flow, cerebral perfusion or place them at risk for cerebral hypoperfusion\n* Patients in whom an invasive arterial cannula cannot be placed",[52,53],"CHILD","ADULT",[55],{"facility":56,"city":57,"state":58,"zip":59,"country":60,"geoPoint":61},"Nationwide Children's Hospital","Columbus","Ohio","43205","United States",{"lat":62,"lon":63},39.96118,-82.99879,[],[66],{"name":67,"affiliation":56,"role":68},"Joseph Tobias, MD","PRINCIPAL_INVESTIGATOR",[],[],{"nct_id":4,"conditions":72,"biomarkers":74},[73],"Scoliosis",[],{"nct_id":4,"found":14,"summary":16,"prompt_version":16}]