[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT06970210":3,"trial-entities:NCT06970210":217,"trial-summary:NCT06970210":220},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":20,"study_type":26,"primary_purpose":27,"phases":28,"enrollment_info":30,"interventions":33,"primary_outcomes":45,"secondary_outcomes":50,"sex":70,"minimum_age":71,"maximum_age":72,"healthy_volunteers":15,"eligibility_criteria":73,"std_ages":77,"locations":80,"central_contacts":90,"overall_officials":91,"references":96,"see_also_links":216},"NCT06970210","IRB#2153765","United4Stroke (U4S) - El Paso Network Stroke Community Program","United4Stroke (U4S) - El Paso Network: Community Health Program With Group-Based Education","ENROLLING_BY_INVITATION","2028-12-20","2025-04","2025-05-14","2025-06-02","University of Texas, El Paso","OTHER",false,"What is United4Stroke (U4S)? United4Stroke is a research program at the University of Texas at El Paso (UTEP) that aims to help stroke survivors become more active and reduce sedentary time through education, movement, and personalized coaching.\n\nWhere Does It Happen?\n\nAll sessions take place at:\n\nUTEP's Rehabilitation Sciences Complex located at 3333 North Mesa Street, El Paso, TX 79902\n\nWhat is Involved?\n\nThe program includes 12 total visits over several months:\n\n* 8 group sessions (held every two weeks)\n* 4 individual evaluation visits (before, during, and after the program)\n\nWho Can Participate?\n\n* Individuals 18 years of age or older who have had a stroke at least 6 months prior to joining the study.\n* Family caregivers may also join\n\nWhat Happens During the Visits?\n\nFirst Visit:\n\n* Learn about the study and give consent\n* Answer questions about memory, movement, general health, and daily activity\n* Do walking and mobility tests\n* Get fitted with a small movement sensor (ActivPAL) and a Fitbit\n\nGroup Sessions (Visits 2-8):\n\n* Topics: physical activity, sitting less, balance and falls, and activities of daily living\n* Led by UTEP physical therapy faculty\n* Includes group discussions and hands-on activities\n* Some participants will also get one-on-one coaching to help with physical activity engagement, daily step count, and reducing sedentary behavior.\n\nFollow-Up Visits (Visits 9 and 11):\n\n* Repeat earlier tests to check progress\n* Share feedback about the program\n\nFinal Visit (Visit 10):\n\n* Celebrate progress!\n* Social gathering, certificates, and a presentation of results\n\nGoal:\n\nTo support stroke survivors in becoming more active and living healthier, more independent lives-step by step.","Specific Aims:\n\nAim 1: To evaluate the adherence rate, attendance, and satisfaction associated with a community health program that combines group-based education with individual coaching sessions for stroke survivors and their caregivers.\n\nHypothesis 1.1: A community health program incorporating group-based education and individual coaching sessions for stroke survivors will demonstrate acceptable rates of adherence and attendance.\n\nHypothesis 1.2: Stroke survivors and their caregivers will report satisfaction with a group-based education community health program.\n\nAim 2: To examine the effects of a community health program that combines group-based education with individual coaching sessions for stroke survivors and their caregivers on physical activity (PA), sedentary behavior (SB), and quality of life (QoL).\n\nHypothesis 2.1: The community health program, integrating group-based education with individual coaching sessions, will increase daily step count among stroke survivors more effectively than group-based education alone.\n\nHypothesis 2.2: The community health program, which combines group-based education with individual coaching sessions, will decrease SB among stroke survivors more effectively than group-based education alone.\n\nHypothesis 2.3: The community health program, which combines group-based education with individual coaching sessions, will improve the QoL of stroke survivors and their caregivers more effectively than group-based education alone.\n\nHypothesis 2.4: The one-month follow-up will show higher retention rates for the group intervention. Specifically, the community health program that combines group-based education with individual coaching will result in a greater rate of maintenance of daily step count, lower time spent in SB, and greater self-reported QoL one month after the program concludes when compared to group-based education alone.\n\nStudy Design and Methods:\n\nThe U4S project will employ a randomized controlled trial (RCT), following the Consolidated Standards of Reporting Trials (CONSORT) design. Participants will be recruited from community health centers and rehabilitation facilities throughout the Paso Del Norte region, supported by local healthcare providers and community organizations. A community engagement strategy will rely on ambassadors utilizing the partner mobile IT platform (High Enroll\u002F Patient Enroll) to promote the study through tailored marketing campaigns. Inclusion criteria are designed to ensure a focus on chronic stroke survivors: individuals aged 18 or older who are at least six months post-stroke, with the ability to participate in group sessions and provide informed consent. Recruitment will be facilitated through outreach to stroke support groups, healthcare providers, and community organizations within the region.\n\nRecruitment and Participants:\n\nPower calculations suggest that the RCT with a 5% significance level and moderate effect size (Cohen's f=0.5) will maintain 80% power with n=17 observations per group and 90% power with n=23 per group. This implies that with at least 46 total participants, we can maintain a well-powered experiment (90%), and with only 34 total subjects, we will have a moderately powered experiment (80%). All power calculations were performed in R 17 using the pwr package18. Over the course of 3 years, we aim to recruit 46 participants, averaging 23 participants per group (control and experimental). Each semester (3 semesters in total) will consist of two cohorts of 4 participants for each group, all of whom will be randomly assigned to either the control or intervention group. Participants in the control group will attend group-based education sessions covering essential stroke recovery topics, including awareness of PA engagement, reduction of SB, performance of activities of daily living (ADLs), and balance and fall risk. Group discussions will encourage social engagement, aiming to foster a sense of community and support among participants. In addition to the group education sessions, participants in the intervention group will receive one-on-one coaching from trained health professionals to set personalized health goals, with a primary focus on increasing daily step count. Coaching sessions will use motivational interviewing techniques to address ambivalence and enhance readiness for behavior change. Individualized action plans will be developed, focusing on the creation of SMART goals to incrementally increase daily steps. Based on baseline data or data collected at each visit, participants will be encouraged to achieve step count increases of 2%, 5%, or 10% per week or visit, depending on their readiness and willingness to progress. The intervention will span 12 weeks, with each group attending twelve visits at two-week intervals. Each session will last approximately one hour and a half, combining interactive education, group discussions, and individualized goal setting. The intervention integrates physical and psychosocial barriers and facilitators with SDH-focused strategies that address barriers commonly faced by Hispanic\u002FLatino stroke survivors.\n\nDescription of Work:\n\nThis research project will encompass twelve visits to UTEP's Physical Therapy and Movement Sciences Department, where our laboratory is located. The first visit to the clinic will include the collection of demographics, sample characterization using scores from the Montreal Cognitive Assessment (MoCa), the Charlson Comorbidity Index (CCI), and the Fugl-Meyer Assessment of Motor Recovery after Stroke (FMA). We will also administer questionnaires that assess physical activity using the Human Activity Profile (HAP), sedentary behavior using the Sedentary Behavior Questionnaire (SBQ), and quality of life using the Stroke Impact Scale (SIS 3.0). Then, we will conduct several functional assessments including the Timed-Up-and-Go (TUG) test, the Five Times Sit to Stand Test (FTSTS), and the Ten Meters Walk Test (10MWT) in a randomized order. At the end of the visit, we will place an ActivPAL sensor on the stroke survivor that will record their number of steps, number of sit to stand transitions, and sedentary behavior based on the amount of time spent in different postural positions (i.e., sitting, lying) for seven days as a baseline measurement prior to the program. Randomization will be performed using sealed, opaque envelopes and the participant will be allocated to the respective group. Then, the stroke survivor and their caregiver (if applicable) will attend a first session with group-based education and the experimental group will receive their first individualized coaching. Zoom calls for the individualized coaching will be scheduled as needed. The program will be composed of seven additional sessions with group-based education and the experimental group will receive personalized coaching regarding step count increase after each session. The group sessions will be led by the principal investigator, and other research personnel. During these sessions, social interactions amongst the stroke survivors and caregivers will be highly encouraged through group activities and conversations. Then, the experimental group of stroke survivors will receive personalized coaching from the research team. Through this individualized coaching, our aim is to support stroke survivors throughout the states of the Transtheoretical Model of Health Behavioral Change. To accomplish this, we will provide the stroke survivors with guided and tailored exercises, set SMART (specific, measurable, achievable, realistic, and timed) goals every two weeks, help the participants in forming long-lasting habits, identify barriers that may restrict the stroke survivors from participating in physical activity, and make proposals to reduce those barriers to implement a more active lifestyle. During the eighth visit, we will also place the ActivPAL sensors onto the participants which will monitor their sedentary behavior based on time spent in different postural positions (i.e., sitting, lying) for seven days. This will serve as a post-program measurement. Then, the stroke survivors and caregivers will be invited back to the lab individually (visit 9) where the stroke survivors will respond to questionnaires that assess physical activity (HAP), sedentary behavior (SBQ), and quality of life (SIS 3.0). Then, we will conduct several functional assessments including the TUG test, the FTSTS test, and the 10MWT that will be conducted in a randomized order. The TUG test will be conducted over three trials consisting of familiarization, self-selected speed, and fast speed. The 10MWT will be conducted over four randomized trials, consisting of two self-selected speed trials, and two fast speed trials. The FTSTS test will be conducted over three trials, in which the participant will be asked to complete each trial as fast as they can. The caregiver will be administered a questionnaire that assesses strain that they may or may not experience as a caregiver (MCSI). During this visit, both the stroke survivor and caregiver will be administered a survey to assess their satisfaction with the program. Then, participants will be invited for a closing event (10th visit) with additional social interactions, games, and distribution of certificates of completion. One month after the closing event, the participants and their caregivers (if applicable) will be invited back for a follow-up assessment comprised of two visits. The follow-up assessment will consist of identical questionnaires, functional assessments, and sensor placement as those described in previous individual visits.\n\nData Analysis:\n\nAim 1: The analysis of adherence rate, attendance frequency, and satisfaction will be accomplished by using descriptive statistics and data visuals, including a general reporting of the mean, minimum and maximum levels observed.\n\nAim 2: The program's effect on measures of QoL, SB, and PA levels will be analyzed by computing a paired t-test between pre- and post- scores that are generated from the questionnaires and assessments described above for control and intervention groups.\n\nExpected Results:\n\nIn the short term, the U4S project is expected to yield measurable improvements in the adherence, attendance, and satisfaction rates of chronic stroke survivors and their caregivers participating in the community-based program. The combined group-based education and individual coaching intervention is anticipated to enhance physical activity, reduce sedentary behavior, and improve quality of life. Outreach efforts with a community engagement strategy will likely result in increased community-wide awareness and participation in the study, surpassing recruitment benchmarks from previous stroke studies. The strategic use of targeted marketing, mobile IT platforms, and Ambassadors will ensure effective engagement with underserved Hispanic\u002FLatino populations in the Paso del Norte region. These short-term outcomes will provide actionable insights into the feasibility and immediate impact of the intervention and the effectiveness of the recruitment strategies. Over the long term, the U4S project is expected to establish a sustainable and scalable community-academic partnership model for addressing health disparities in the Paso del Norte region and beyond. The program's success will provide a foundation for advancing evidence-based, culturally tailored interventions to improve rehabilitation outcomes for chronic stroke survivors. The findings will contribute to the scientific understanding of community-engaged health programs and inform policies to reduce health disparities in underserved populations.\n\nThe data and insights generated from this project will provide the essential evidence to refine our research questions, methodologies, and hypotheses. The evidence from this project will validate our innovative intervention approach, confirming its feasibility and potential effectiveness in improving the quality of life, physical activity, and self-reported health outcomes for stroke survivors and their caregivers within the Hispanic\u002FLatino community.",[19],"Stroke",[19,21,22,23,24,25],"Quality of Life","Sedentary Behaviors","Sedentary Lifestyle","Physical Inactivity","Community Health Education","INTERVENTIONAL","TREATMENT",[29],"NA",{"count":31,"type":32},46,"ESTIMATED",[34,41],{"type":35,"name":36,"description":37,"armGroupLabels":38},"BEHAVIORAL","Group-Based Education","The group-based education will consist of group sessions led by research staff, covering topics such as physical activity, sedentary behavior, balance and fall prevention, and activities of daily living. Social interactions amongst group members will be facilitated through group activities and discussions regarding the topics being discussed.",[39,40],"Group-Based Education Only","Group-Based Education plus Individualized Coaching",{"type":35,"name":42,"description":43,"armGroupLabels":44},"Individualized Coaching","Individualized coaching aims to increase the participants daily step count. Participants will be encouraged to achieve step count increases of 2%, 5%, or 10% per week or visit, depending on their readiness and willingness to progress. SMART goal-setting strategies will be employed to assist with the goal setting. Participants may also receive coaching related to reducing sedentary behavior and engaging in physical activities.",[40],[46],{"measure":47,"description":48,"timeFrame":49},"Daily Step Count","Daily step count data will be collected.","Baseline, week 6 (during intervention), week 13 (post-intervention), and week 19 (follow-up).",[51,54,58,61,63,66,68],{"measure":52,"description":53,"timeFrame":49},"Sedentary Behavior (Objective)","Sedentary behavior will be assessed using the ActivPAL sensor, which will be adhered to the participant's thigh and worn continuously for seven days. The ActivPAL monitors posture and movement, providing detailed data on time spent sitting, standing, walking, and lying down. Additionally, the sensor provides data of daily sit to stand transition counts. Sensors will be deployed at four timepoints: baseline, mid-program, post-intervention, and follow-up.",{"measure":55,"description":56,"timeFrame":57},"Sedentary Behavior (Subjective)","Data for sedentary behavior will be collected using the Sedentary Behavior Questionnaire (SBQ). This questionnaire asked the participants how long they believe they spend participating in 11 different activities during week and weekend days.","Baseline, week 13 (post-intervention), and week 19 (follow-up).",{"measure":59,"description":60,"timeFrame":57},"Quality of Life (QoL)","Data on QoL will be collected using the Stroke Impact Scale (SIS 3.0). The Stroke Impact Scale (SIS) is a self-report questionnaire that evaluates disability and health-related quality of life after stroke (Mudler \\& Nijland, 2016). It is a 59-item questionnaire, assessing eight domains: strength, hand function, activities of daily living, mobility, communication, emotion, memory and thinking, and participation\u002Frole function. Each item is presented as a 5-point Likert scale, allowing the participant to rate the level of difficulty they experience in completing each item. Additionally, the participant is asked to rate how much they think that they have recovered from their stroke on a 0-100 scale.",{"measure":59,"description":62,"timeFrame":57},"Data on QoL will be collected using the Modified Caregiver Strain Index (MCSI). The MCSI is a 13 item questionnaire administered to caregivers (if applicable). The questionnaire assesses strain related to the following domains: financial, physical, psychological, social, and personal. Higher scores indicate more strain.",{"measure":64,"description":65,"timeFrame":57},"Mobility Performance","Data for mobility performance will be collected using the Timed-Up-and-Go Test (TUG). The TUG test assesses mobility and fall risk. During the test, the participant is instructed to stand up from a chair, walk three meters, turn around, walk back to the chair, and sit back down. The test will be conducted over three trials: familiarization, self-selected speed, and fast speed.",{"measure":64,"description":67,"timeFrame":57},"Data for mobility performance will be collected using the Five Times Sit to Stand (FTSTS) Test. The FTSTS test assesses functional mobility and strength. During the test, the participant is instructed to rise to a full standing position and return to sitting five times as quickly as possible, without using their arms.",{"measure":64,"description":69,"timeFrame":57},"Data for mobility performance will be collected using the Ten Meters Walk Test (10MWT). The 10MWT assesses functional mobility and gait. During the test, the participant is instructed to walk 10 meters (with 2 additional meters on each end of the walkway for acceleration and deceleration). The test will be conducted over 4 trials presented in a randomized order: 2 self-selected comfortable walking speed, and 2 at a fast walking speed.","ALL","18 Years",null,{"inclusion":74,"exclusion":75,"raw_text":76},[],[],"Inclusion Criteria: Individuals will be included if they are ≥ 18-years old, have had a stroke at least 6 months prior to baseline assessment, have a means of transportation to the UTEP physical therapy building to attend the program\u002Fvisits, and are clinically stable (the participant's health is not rapidly worsening and there may be a level of stability in their overall health status).\n\nExclusion Criteria: Individuals will be excluded if they are unable to consent, if they do not have a means of transportation to attend the program\u002Fstudy visits, if they require a caregiver and the caregiver is unable to attend, if they walk greater than an average of 7,000 steps a day, if they walk at a speed less than or equal to 0.3 m\u002Fs, or if the participant attends less than 60% of the group-based educational sessions.",[78,79],"ADULT","OLDER_ADULT",[81],{"facility":82,"city":83,"state":84,"zip":85,"country":86,"geoPoint":87},"The University of Texas at El Paso: Rehabilitation Sciences Complex","El Paso","Texas","79902","United States",{"lat":88,"lon":89},31.75872,-106.48693,[],[92],{"name":93,"affiliation":94,"role":95},"Camila Torriani-Pasin, PhD, PT","The University of Texas at El Paso","PRINCIPAL_INVESTIGATOR",[97,101,104,107,110,113,116,119,122,125,128,131,134,137,140,143,146,149,152,155,158,161,164,167,170,173,176,178,181,184,187,190,193,195,198,201,204,207,210,213],{"pmid":98,"type":99,"citation":100},"12234086","BACKGROUND","Gladstone DJ, Danells CJ, Black SE. 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