[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT06976528":3,"trial-entities:NCT06976528":76,"trial-summary:NCT06976528":80},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":16,"conditions":17,"keywords":19,"study_type":26,"primary_purpose":13,"phases":27,"enrollment_info":29,"interventions":32,"primary_outcomes":38,"secondary_outcomes":43,"sex":48,"minimum_age":49,"maximum_age":50,"healthy_volunteers":14,"eligibility_criteria":51,"std_ages":55,"locations":57,"central_contacts":72,"overall_officials":73,"references":74,"see_also_links":75},"NCT06976528","20237802","Understanding the Associations Between Romantic Relationship Conflict, Psychophysiological Responding and Alcohol Misuse Among Emerging Adults","RECRUITING","2028-07-31","2025-09","2026-08-10","2025-09-26","New York University","OTHER",true,"Emerging Adults (EA) engage in heavy episodic drinking (HED) at a greater quantity and frequency than any other time in their lives, which may lead to significant short- and long-term consequences. Although much is known about the influence of peers in EA alcohol use, there is a dearth of research examining the ways in which romantic partners influence EA drinking behaviors. The proposed study bridges a crucial gap in the existing literature by examining behavioral and physiological risk and resilience factors in the acute link between EA relationship conflict and alcohol consumption. EA couples will engage in two conflict resolution tasks interspersed with two puzzle tasks and two alcohol administration procedures. Because high frequency heart rate variability (HF-HRV) is associated with alcohol use and emotion regulation during stressful experiences, HF-HRV and other physiological data will be collected throughout the laboratory procedures.",null,[18],"Heavy Episodic Drinking",[20,21,22,23,24,25],"couples","emerging adults","young adults","binge drinking","alcohol use","conflict","INTERVENTIONAL",[28],"NA",{"count":30,"type":31},160,"ESTIMATED",[33],{"type":13,"name":34,"description":35,"armGroupLabels":36},"Alcohol administration","In this study, participants complete two tasks, then are administered alcohol. Next, they repeat the tasks.",[37],"Single Arm",[39],{"measure":40,"description":41,"timeFrame":42},"Alcohol consumption","Amount of alcohol consumed during the study","~20 minutes",[44],{"measure":45,"description":46,"timeFrame":47},"High frequency heart rate variability (HF-HRV)","High frequency heart rate variability (HF-HRV) is a neurally-derived measure of parasympathetic activity that may partially explain the association between stressful relationship conflict and alcohol misuse. HF-HRV is a measure of the variability in interbeat intervals, or the time in between beats of the heart.","~3 hours","ALL","21 Years","29 Years",{"inclusion":52,"exclusion":53,"raw_text":54},[],[],"Inclusion Criteria:\n\n1. Age 21-29 years old\n2. Must be in a committed romantic relationship of at least 3 months duration\n3. Must report at least 2 HED episodes in the past 30 days (5 or more drinks within 2 hours for males, 4 or more drinks within 2 hours for females)\n4. Must self-report that they have - on at least three occasions during the past year - consumed a quantity of alcohol that is equal to or greater than the standard dose administered for their weight in the laboratory\n\nExclusion Criteria:\n\n1. Meeting DSM-5 criteria for a history of or current neurological, psychotic, or bipolar disorders\n2. History of self-reported head trauma requiring medical treatment\n3. Body weight exceeding 250 pounds\n4. Current enrollment in treatment or seeking treatment for a substance or alcohol use disorder\n5. Current suicidal or homicidal intent\n6. Serious cardiovascular health conditions (e.g. pacemaker, cardiac arrhythmia, hypertension) that may alter normative cardiac functioning\n7. Treatment on medications such as lithium, methadone, alpha or beta blockers or cholinergic\u002Fanticholinergic medications likely to confound normative cardiovascular responding or response to alcohol administration. Stimulant or benzodiazepine medication use is permissible provided participants do not take medication on the day of study participation\n8. Severe and\u002For unilateral physical IPV with your current partner at any time\n9. Sexual IPV with current partner at any time\n10. Fear of current partner\n11. Pregnancy or breastfeeding\n12. Severe Alcohol Use Disorder (as defined by the DSM-5)\n13. Current diagnosis of anorexia or bulimia",[56],"ADULT",[58],{"facility":59,"status":7,"city":60,"state":60,"zip":61,"country":62,"contacts":63,"geoPoint":69},"386 Park Avenue South","New York","10016","United States",[64],{"name":65,"role":66,"phone":67,"email":68},"Sarah Harris","CONTACT","914-419-4745","sh8527@nyu.edu",{"lat":70,"lon":71},40.71427,-74.00597,[],[],[],[],{"nct_id":4,"conditions":77,"biomarkers":79},[78,18],"Alcohol use disorder",[],{"nct_id":4,"found":14,"summary":81,"prompt_version":91},{"design":82,"status":83,"heading":84,"summary":85,"follow_up":86,"word_count":87,"commitments":88,"compensation":89,"drugs_mentioned":90},"This is an observational study planning to enroll 160 participants. It is not testing a specific treatment, but rather observing behaviors.","completed","Understanding Romantic Relationship Conflict and Alcohol Misuse in Young Adults","This study is looking at how conflict in romantic relationships might be connected to heavy episodic drinking (having many drinks in a short time) in young adults. Researchers want to understand how relationship issues affect drinking behaviors. They will observe couples aged 21-29 who are in a committed relationship and have a history of heavy episodic drinking. Participants will engage in conflict resolution tasks, puzzle tasks, and alcohol administration procedures. The main goal is to measure alcohol consumption during these activities, about 20 minutes after they start. This study aims to help us better understand the link between relationship stress and alcohol use in young adults.","Alcohol consumption will be measured at approximately 20 minutes.",106,"You and your partner would participate in conflict resolution tasks, puzzle tasks, and alcohol administration procedures.","Not stated in the trial record.",[],"v2"]