[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07052357":3,"trial-entities:NCT07052357":87,"trial-summary:NCT07052357":91},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":16,"conditions":17,"keywords":22,"study_type":23,"primary_purpose":24,"phases":25,"enrollment_info":27,"interventions":30,"primary_outcomes":37,"secondary_outcomes":52,"sex":53,"minimum_age":54,"maximum_age":55,"healthy_volunteers":56,"eligibility_criteria":57,"std_ages":65,"locations":68,"central_contacts":77,"overall_officials":78,"references":79,"see_also_links":80},"NCT07052357","HUM00033029.25","Intern Health Study 2025","ENROLLING_BY_INVITATION","2026-06-30","2025-06","2025-07-04","2025-04-03","University of Michigan","OTHER",false,"The aim of this study is to evaluate the efficacy of using a reinforcement learning algorithm to determine the optimal content of a mobile health intervention (message delivered via smartphone) for improving the mood, physical activity, and sleep of medical interns.","Due to their high workloads, less sleep and physical activity and other stressors, medical interns suffer from depression at higher rates than the general population. The goal of this study is to evaluate the efficacy of a mobile health intervention intending to help prevent the degradation of health behaviors and the development of depression. The intervention sends mobile phone notifications which aim to help interns improve their mood, maintain physical activity, and obtain adequate sleep during their internship year. A reinforcement learning algorithm will use prior survey, daily mood, and wearable data to make three types of choices each day: 1) whether to send a message or not on a given day, and, if sending a message, 2) the therapeutic strategy (Behavioral Strategy, Cognitive Strategy, Mindfulness, Motivational Interviewing, Distanced Self-Talk), and 3) whether or not to include feedback (the intern's own data) in the message.",[18,19,20,21],"Depression - Major Depressive Disorder","Mood","Sleep","Physical Activity",[],"INTERVENTIONAL","PREVENTION",[26],"NA",{"count":28,"type":29},1000,"ESTIMATED",[31],{"type":32,"name":33,"description":34,"armGroupLabels":35},"BEHAVIORAL","Intern Health Study behavioral change mobile notification","The study's mobile app will be used to deliver push notifications. The notifications appear on the participant's phone lock screen. The notifications include 3 categories: mood notifications, activity notifications, sleep notifications. Mood notifications aim to increase the participant's mood. Activity notifications aim to increase the participant's physical activity. Sleep notifications aim to increase the participant's sleep duration. All notifications are categorized as one of five therapeutic approaches: 1) CBT-Behavioral, 2) CBT-Cognitive, 3) Distanced Self-Talk, 4) Mindfulness, 5) Motivational Interviewing.",[36],"Within-participant micro-randomization",[38,42,45,48],{"measure":39,"description":40,"timeFrame":41},"Average daily mood","Through the mobile app, participants enter a mood score (scale 1 - 10) every day of the study. 1 corresponds to lowest mood and 10 corresponds to highest mood.","Daily, through study completion at the end of intern year (1 year)",{"measure":43,"description":44,"timeFrame":41},"Average daily step count","Participant's daily step counts are recorded through a fitness tracker. High step counts are considered a positive outcome as it indicates more physical activity.",{"measure":46,"description":47,"timeFrame":41},"Average nightly sleep duration","Participant's nightly sleep duration (in minutes) is recorded through a fitness tracker. High sleep duration is considered a positive outcome.",{"measure":49,"description":50,"timeFrame":51},"Patient Health Questionnaire-9 (PHQ-9)","Prior to the start of the intervention and at quarterly intervals throughout internship year, all participants complete the Patient Health Questionnaire 9. High scores on the PHQ-9 correspond to a larger number of depressive symptoms.","Quarterly (every 3 months for 1 year)",[],"ALL","18 Years",null,true,{"inclusion":58,"exclusion":62,"raw_text":64},[59,60,61],"Medical intern during the 2025-2026 internship year","iPhone or Android phone user","Completed the Intern Health Study consent and baseline survey by June 20 prior to the start of intern year",[63],"None","Inclusion Criteria:\n\n* Medical intern during the 2025-2026 internship year\n* iPhone or Android phone user\n* Completed the Intern Health Study consent and baseline survey by June 20 prior to the start of intern year\n\nExclusion Criteria:\n\n* None",[66,67],"ADULT","OLDER_ADULT",[69],{"facility":12,"city":70,"state":71,"zip":72,"country":73,"geoPoint":74},"Ann Arbor","Michigan","48375","United States",{"lat":75,"lon":76},42.27756,-83.74088,[],[],[],[81,84],{"label":82,"url":83},"Sen Lab Website","https:\u002F\u002Fwww.srijan-sen-lab.com\u002Fintern-health-study",{"label":85,"url":86},"Study Participant Website","https:\u002F\u002Fwww.internhealthstudy.org\u002F",{"nct_id":4,"conditions":88,"biomarkers":90},[89],"Unipolar Depression",[],{"nct_id":4,"found":14,"summary":55,"prompt_version":55}]