[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07081841":3,"trial-entities:NCT07081841":74,"trial-summary:NCT07081841":79},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":21,"study_type":22,"primary_purpose":17,"phases":23,"enrollment_info":24,"interventions":27,"primary_outcomes":35,"secondary_outcomes":40,"sex":41,"minimum_age":17,"maximum_age":17,"healthy_volunteers":42,"eligibility_criteria":43,"std_ages":48,"locations":52,"central_contacts":70,"overall_officials":71,"references":72,"see_also_links":73},"NCT07081841","ASK-PD0-CS002","AB-1005 Long-Term Follow-up Study","Long-Term Safety and Efficacy Follow-up of AB-1005 Gene Transfer Study Participants With Parkinson's Disease or Multiple System Atrophy","ENROLLING_BY_INVITATION","2038-03-30","2025-09","2025-10-02","2025-09-04","AskBio Inc","INDUSTRY",true,"This is an observational, long term, follow-up study for participants with Parkinson's disease (PD) or Multiple System Atrophy-Parkinsonian subtype (MSA-P) who participated in prior interventional studies with AB-1005. It is intended to better understand the long-term safety of AB-1005, how well tolerated it is and how long lasting the effects are.",null,[19,20],"Parkinson's Disease","Multiple System Atrophy, Parkinson Variant",[],"OBSERVATIONAL",[],{"count":25,"type":26},132,"ESTIMATED",[28],{"type":29,"name":30,"description":31,"armGroupLabels":32},"OTHER","Observation","This is an observational study in which safety laboratories and non-invasive routine clinical assessments are conducted to gauge long term safety and efficacy.",[33,34],"Participants with MSA-P","Participants with PD",[36],{"measure":37,"description":38,"timeFrame":39},"Long term safety and tolerability","Measure of the occurrence of serious and non-serious adverse events","Up to 10 years post surgery",[],"ALL",false,{"inclusion":44,"exclusion":46,"raw_text":47},[45],"PD and MSA-P participants that are or were enrolled in an interventional AB-1005 study and provide informed consent",[],"Inclusion Criteria:\n\n* PD and MSA-P participants that are or were enrolled in an interventional AB-1005 study and provide informed consent\n\nExclusion Criteria:\n\n* There are no exclusion criteria",[49,50,51],"CHILD","ADULT","OLDER_ADULT",[53,62],{"facility":54,"city":55,"state":56,"zip":57,"country":58,"geoPoint":59},"University of California San Francisco","San Francisco","California","94143","United States",{"lat":60,"lon":61},37.77493,-122.41942,{"facility":63,"city":64,"state":65,"zip":66,"country":58,"geoPoint":67},"Ohio State University","Columbus","Ohio","43210",{"lat":68,"lon":69},39.96118,-82.99879,[],[],[],[],{"nct_id":4,"conditions":75,"biomarkers":78},[76,77],"Multiple System Atrophy","Parkinson Disease",[],{"nct_id":4,"found":42,"summary":17,"prompt_version":17}]