[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07091968":3,"trial-entities:NCT07091968":87,"trial-summary:NCT07091968":91},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":21,"study_type":22,"primary_purpose":23,"phases":24,"enrollment_info":26,"interventions":29,"primary_outcomes":35,"secondary_outcomes":40,"sex":44,"minimum_age":45,"maximum_age":46,"healthy_volunteers":47,"eligibility_criteria":48,"std_ages":60,"locations":63,"central_contacts":78,"overall_officials":81,"references":85,"see_also_links":86},"NCT07091968","Pro00142801","Feasibility of a Technology-Based Intervention for Depression Referral Uptake in Cancer Survivors","Pilot Feasibility Trial to Evaluate a Technology-Enabled Approach to Enhance Depression Referral Uptake Among Cancer Survivors","RECRUITING","2026-12","2025-12","2026-07-13","2026-01-16","Medical University of South Carolina","OTHER",true,"Depression is very common in cancer survivors but there are challenges to linking those in need of treatment efficiently to care. In this study, investigators will test the feasibility and acceptability of a new text-based approach to connect cancer survivors with depression with care.","The objectives of this study are 1) to evaluate the feasibility and acceptability of a technology-enabled approach to improve referral uptake among cancer survivors and 2) to evaluate the preliminary efficacy of this approach to improve referral uptake compared to usual care among cancer survivors.",[19,20],"Cancer","Depression",[],"INTERVENTIONAL","SUPPORTIVE_CARE",[25],"NA",{"count":27,"type":28},60,"ESTIMATED",[30],{"type":31,"name":32,"description":33,"armGroupLabels":34},"BEHAVIORAL","Technology-Enabled Tailored Referral","Participants in the intervention arm will receive a technology-enabled, text-based referral platform designed to improve depression referral uptake. The platform includes an initial text with a brief video explaining common barriers, tailored text messages based on participant-identified barriers, and an automated referral link. Messages are mapped to stages of readiness using the Transtheoretical Model and sent every two days over a two-week period to non-responders or decliners. This approach aims to engage survivors with depression through personalized, accessible, and stage-matched communication.",[32],[36],{"measure":37,"description":38,"timeFrame":39},"Feasibility and Acceptability","The co-primary outcomes are acceptability and feasibility of the technology-enabled referral intervention. Acceptability will be measured using the System Usability Scale (SUS) at 6 weeks, with a score ≥80 indicating high acceptability. Feasibility will be assessed by determining whether key components of the intervention were successfully delivered and engaged with over the course of the 4 week intervention, including: (1) initiation of text-based contact, (2) delivery of tailored messages, and (3) access of the automated referral link by the participant. Additionally, participant engagement will be evaluated by tracking whether they opened the initial message, viewed the embedded video, and read the tailored text messages. These outcomes will be summarized using a Bayesian beta-binomial approach to determine go\u002Fno-go decision thresholds for future scale-up.","6 weeks",[41],{"measure":42,"description":43,"timeFrame":39},"Referral Uptake","Referral uptake is defined as whether a participant initiates a mental health treatment referral at 6 weeks. It will be measured through participant self-report and, when available, verified via electronic health records or provider confirmation.","ALL","18 Years",null,false,{"inclusion":49,"exclusion":56,"raw_text":59},[50,51,52,53,54,55],"age \\> 18 years","diagnosis of cancer","upcoming appointment in an HCC or HCN oncology clinic within 14 days","English proficiency","ownership of a cellphone with SMS text capability.","elevated depressive symptoms at screening (as measured by \\> 3 on the PHQ-2)",[57,58],"cognitive impairment as evaluated by attending physician","currently receiving counseling for depression","Inclusion Criteria:\n\n* age \\> 18 years\n* diagnosis of cancer\n* upcoming appointment in an HCC or HCN oncology clinic within 14 days\n* English proficiency\n* ownership of a cellphone with SMS text capability.\n* elevated depressive symptoms at screening (as measured by \\> 3 on the PHQ-2)\n\nExclusion Criteria:\n\n* cognitive impairment as evaluated by attending physician\n* currently receiving counseling for depression",[61,62],"ADULT","OLDER_ADULT",[64],{"facility":13,"status":8,"city":65,"state":66,"zip":67,"country":68,"contacts":69,"geoPoint":75},"Charleston","South Carolina","29425","United States",[70],{"name":71,"role":72,"phone":73,"email":74},"Lily Research Coordinator, MPH","CONTACT","843-792-5182","lir301@musc.edu",{"lat":76,"lon":77},32.77632,-79.93275,[79],{"name":80,"role":72,"phone":73,"email":74},"Lily P Research Assistant\u002FCoordinator, MPH",[82],{"name":83,"affiliation":13,"role":84},"Katherine Sterba, PhD","PRINCIPAL_INVESTIGATOR",[],[],{"nct_id":4,"conditions":88,"biomarkers":90},[20,89],"Malignant Neoplasm",[],{"nct_id":4,"found":15,"summary":92,"prompt_version":102},{"design":93,"status":94,"heading":95,"summary":96,"follow_up":97,"word_count":98,"commitments":99,"compensation":100,"drugs_mentioned":101},"This interventional study aims to enroll 60 participants. It will compare a technology-enabled approach to usual care.","completed","Study for Technology-Based Depression Referral in Cancer Survivors","This study is testing a new text-based approach called \"Technology-Enabled Tailored Referral\" to help cancer survivors with depression connect with care. Many cancer survivors experience depression, and this study aims to make it easier for them to get the help they need. We want to see if this text-based platform is practical to use and if people like it. You might be able to join if you are over 18, have a cancer diagnosis, have an upcoming oncology appointment, speak English, own a cellphone with text ability, and have elevated depressive symptoms. The study's current status is unclear, and it plans to enroll 60 participants.","Feasibility and acceptability will be measured at 6 weeks.",105,"Not specified in the trial record.","Not stated in the trial record.",[32],"v2"]