[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07221396":3,"trial-entities:NCT07221396":108,"trial-summary:NCT07221396":113},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":22,"study_type":28,"primary_purpose":29,"phases":30,"enrollment_info":32,"interventions":35,"primary_outcomes":46,"secondary_outcomes":65,"sex":73,"minimum_age":74,"maximum_age":17,"healthy_volunteers":15,"eligibility_criteria":75,"std_ages":89,"locations":92,"central_contacts":101,"overall_officials":102,"references":106,"see_also_links":107},"NCT07221396","2000040872","LDART for Stimulant Use Disorder","Pilot Study of the Digital Intervention LDART for Stimulant Use Disorder","ENROLLING_BY_INVITATION","2027-04-01","2026-04","2026-05-01","2026-04-29","Yale University","OTHER",false,"The goal of this study is to evaluate the feasibility, acceptability, and preliminary efficacy of a digital intervention called LDART in adults with stimulant use disorder.",null,[19,20,21],"Stimulant Use Disorder","Cocaine Use Disorder","Methamphetamine Use Disorder",[23,24,25,26,27],"social support","digital intervention","mutual-help groups","stimulant use disorder","addiction recovery","INTERVENTIONAL","TREATMENT",[31],"NA",{"count":33,"type":34},80,"ESTIMATED",[36,41],{"type":37,"name":38,"description":39,"armGroupLabels":40},"DEVICE","LDART","Let's Do Addiction Recovery Together! (LDART) is a web-based intervention grounded in social cognitive theory that is designed to reduce hazardous alcohol use. It has three active ingredients: 1) daily recovery goal setting and tracking, 2) motivational video, audio, and written messages from individuals in recovery, and 3) information on several community-based recovery groups (e.g., mutual-help groups, recovery community centers) that provide free, publicly available meetings and activities. Participants receive a text message reminder each night to go to the website to complete the activities, and a text message reminder each morning of the goal they set for themselves, with the option to change it. It only takes a few minutes to use LDART each day over the 4-week intervention period.",[38],{"type":42,"name":43,"description":44,"armGroupLabels":45},"BEHAVIORAL","Psychoeducational booklet","This is a 10-page PDF on stimulant use disorder created by the American Society of Addiction Medicine and American Academy of Addiction Psychiatry. It contains information about stimulant intoxication and withdrawal and treatment options. Participants will be encouraged to access this booklet for a few minutes each night over the 4-week intervention period.",[43],[47,51,54,57,61],{"measure":48,"description":49,"timeFrame":50},"Recruitment rate","The percentage of eligible participants who are enrolled relative to the total number of eligible potential participants who completed the screening.","From enrollment to the final assessment time point (Day 56)",{"measure":52,"description":53,"timeFrame":50},"Accrual rate","The rate of enrollment, defined as number of participants enrolled per month.",{"measure":55,"description":56,"timeFrame":50},"Retention rate","The percentage of enrolled participants who complete all study-related procedures (i.e., all three assessments).",{"measure":58,"description":59,"timeFrame":60},"Intervention engagement","Number of nights enrolled participants completed the activities on the LDART website, out of 28 nights.","From beginning the intervention (Day 1) to the end of the intervention period (Day 28)",{"measure":62,"description":63,"timeFrame":64},"Intervention acceptability","Rating scores on the end-user version of the Mobile App Rating Scale (uMARS). Total score range 1-5 with higher scores indicating a better quality app.","The second assessment time point (post-intervention, Day 28)",[66,70],{"measure":67,"description":68,"timeFrame":69},"Change from baseline in stimulant use frequency","Change in self-reported number of days when any stimulants were used in the past 28 days, as measured using the Timeline Follow-back.","Baseline (Day 0), Post-intervention (Day 28), 1-month post-intervention (Day 56)",{"measure":71,"description":72,"timeFrame":69},"Change from baseline in number of hours spent engaging with recovery groups","Self-reported number of hours spent engaging with recovery groups in the past 28 days, as measured using a modified Timeline Follow-back","ALL","18 Years",{"inclusion":76,"exclusion":83,"raw_text":88},[77,78,79,80,81,82],"18 years of age or older","Currently reside in Connecticut, USA","Have a smartphone that can send and receive text messages and have internet access that can be access over the course of a month","Substance (Stimulant) Use Symptom Checklist ≥2, indicating past-year stimulant use disorder","Had high frequency of cocaine use (≥5 days) in the past 28 days","Have some self-reported desire to cut down or quit stimulants",[84,85,86,87],"Unable to provide informed consent, as assessed by the consent quiz","Unable to speak, read, or write in English","Vulnerable population status","Unlikely to be able to complete study procedures in the next 2 months","Inclusion criteria:\n\n* 18 years of age or older\n* Currently reside in Connecticut, USA\n* Have a smartphone that can send and receive text messages and have internet access that can be access over the course of a month\n* Substance (Stimulant) Use Symptom Checklist ≥2, indicating past-year stimulant use disorder\n* Had high frequency of cocaine use (≥5 days) in the past 28 days\n* Have some self-reported desire to cut down or quit stimulants\n\nExclusion criteria:\n\n* Unable to provide informed consent, as assessed by the consent quiz\n* Unable to speak, read, or write in English\n* Vulnerable population status\n* Unlikely to be able to complete study procedures in the next 2 months",[90,91],"ADULT","OLDER_ADULT",[93],{"facility":13,"city":94,"state":95,"zip":96,"country":97,"geoPoint":98},"New Haven","Connecticut","06520","United States",{"lat":99,"lon":100},41.30815,-72.92816,[],[103],{"name":104,"affiliation":13,"role":105},"Li Yan McCurdy, PhD","PRINCIPAL_INVESTIGATOR",[],[],{"nct_id":4,"conditions":109,"biomarkers":112},[110,20,111],"Amphetamine-induced organic mental disorder","Stimulant use disorder",[],{"nct_id":4,"found":114,"summary":115,"prompt_version":124},true,{"design":116,"status":117,"heading":6,"summary":118,"follow_up":119,"word_count":120,"commitments":121,"compensation":122,"drugs_mentioned":123},"This interventional study aims to enroll 80 participants. It is evaluating a digital intervention called LDART.","completed","This study is testing a web-based program called LDART, which stands for \"Let's Do Addiction Recovery Together!\" LDART is designed to help adults with stimulant use disorder, including those with cocaine or methamphetamine use disorder. It uses daily goal setting, tracking, and motivational messages. Some participants will also receive a psychoeducational booklet about stimulant use disorder. The main goal of this study is to see if LDART is practical, acceptable to users, and shows early signs of being effective. To join, you must be 18 or older, live in Connecticut, have a smartphone with internet, and have used stimulants frequently in the past month. The study is currently unclear on its recruitment status.","The study measures recruitment, accrual, and retention rates from enrollment to the final assessment time point (Day 56).",113,"You would need to have a smartphone that can send and receive text messages and has internet access for about a month.","Not stated in the trial record.",[38,43],"v2"]