[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07321652":3,"trial-entities:NCT07321652":2004,"trial-summary:NCT07321652":2013},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":21,"study_type":22,"primary_purpose":23,"phases":24,"enrollment_info":26,"interventions":29,"primary_outcomes":60,"secondary_outcomes":65,"sex":66,"minimum_age":67,"maximum_age":68,"healthy_volunteers":15,"eligibility_criteria":69,"std_ages":114,"locations":116,"central_contacts":1993,"overall_officials":1998,"references":2002,"see_also_links":2003},"NCT07321652","A042302","Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL\u002FSLL","Phase III Evaluation of Fixed Duration Zanubrutinib Plus Sonrotoclax-Based Therapy Compared to Continuous Zanubrutinib in Previously Untreated Older Patients With Chronic Lymphocytic Leukemia\u002FSmall Lymphocytic Lymphoma (CLL\u002FSLL)","RECRUITING","2038-09-30","2026-08","2026-08-05","2026-04-30","Alliance for Clinical Trials in Oncology","OTHER",false,"This phase III trial compares the effect of adding sonrotoclax to zanubrutinib versus zanubrutinib alone for the treatment of patients with untreated chronic lymphoblastic leukemia (CLL)\u002Fsmall lymphocytic lymphoma (SLL). Sonrotoclax is in a class of medications called B-cell lymphoma-2 (BCL-2) inhibitors. It may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. Zanubrutinib is in a class of medications called kinase inhibitors. It blocks a protein called BTK, which is present on B-cell (a type of white blood cells) cancers such as mantel cell lymphoma at abnormal levels. This may help keep cancer cells from growing and spreading. Giving sonrotoclax and zanubrutinib may be more effective than zanubrutinib alone for the treatment of untreated CLL\u002FSLL.","PRIMARY OBJECTIVES:\n\nI. To compare the progression free survival (PFS) between minimal residual disease (MRD)-guided zanubrutinib sonrotoclax therapy to continuous zanubrutinib as control.\n\nII. To determine the PFS comparing fixed duration zanubrutinib sonrotoclax therapy to continuous zanubrutinib as control.\n\nSECONDARY OBJECTIVES:\n\nI. To compare the PFS between the patients with MRD-detectable disease treated with fixed duration zanubrutinib sonrotoclax to the PFS of the patients with MRD detectable disease who receive one additional year of combination therapy.\n\nII. To determine the overall survival of all arms of the study. III. To determine the frequency of patients with MRD-detectable disease who convert to undetectable MRD, and at what depth and for how long, after receiving an extra year of combination therapy on the MRD-guided zanubrutinib sonrotoclax therapy arm.\n\nIV. To determine and compare the overall response rate (ORR defined as PR, CR, CCR, CRi) and complete remission rate (CR) after 14 cycles of therapy among the three arms.\n\nV. To compare time to the next CLL\u002FSLL therapy among treatment arms. VI. To determine the rates and severity of toxicity in each arm, with a particular focus on adverse events of special interest that include infections, cardiovascular events (arrhythmias, heart failure, hypertension), tumor lysis syndrome, bleeding events, cytopenias, and second malignancies.\n\nVII. To compare patient-reported symptomatic adverse events as assessed by the Patient Reported Outcome-Common Terminology Criteria for Adverse Events (PRO-CTCAE) between arms 1 and 2.\n\nEXPLORATORY OBJECTIVES:\n\nI. To compare the best achieved rate of undetectable MRD (uMRD) between the fixed duration zanubrutinib sonrotoclax arm and the MRD guided zanubrutinib sonrotoclax arm.\n\nII. To compare rates of undetectable MRD measured by the immunoglobulin heavy chain (IGH) sequencing assay ClonoSeq (sensitivity 1 in 10\\^-6) to undetectable MRD measured by standard six-color flow cytometry (uMRD4), and to compare results from bone marrow to peripheral blood.\n\nOUTLINE: Patients are randomized to 1 of 2 arms.\n\nARM 1: Patients receive zanubrutinib orally (PO) twice daily (BID) on days 1-28 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients undergo restaging starting at cycle 15 day 1. Patients with at least partial remission continue therapy as described above. Patients with progressive disease proceed to follow up. Patients undergo computed tomography (CT) scan, bone marrow aspiration and blood sample collection throughout the study.\n\nARM 2: Patients receive zanubrutinib PO BID on days 1-28 of each cycle. Starting cycle 4 day 1 patients also receive sonrotoclax PO daily (QD) on days 1-28 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients undergo restaging starting at cycle 15 day 1. Patients with undetectable MRD and a response of PR, partial response with persistent lymphocytosis (PR-L), CR, CCR or CRi stop therapy at cycle 15 day 28 and proceed to follow up. Patients with detectable MRD and an objective response to therapy are re-randomized to arm 2B or arm 2C.\n\nARM 2B: Patients continue zanubrutinib PO BID sonrotoclax PO QD on days 1-28 of each cycle. Cycles repeat every 28 days for an additonal 12 cycles in the absence of disease progression or unacceptable toxicity.\n\nARM 2C: Patients discontinue therapy starting at cycle 15 day 28 and proceed to follow up.\n\nPatients undergo CT scan, bone marrow aspiration and blood sample collection throughout the study.\n\nAfter completion of study treatment, patients are followed up every 3 months for 3 years then every 6 months until 10 years for study registration. Patients with progression or the start of non protocol CLL directed therapy are followed every 6 months for 10 years from registration.",[19,20],"Chronic Lymphocytic Leukemia","Small Lymphocytic Leukemia",[],"INTERVENTIONAL","TREATMENT",[25],"PHASE3",{"count":27,"type":28},466,"ESTIMATED",[30,37,40,48,52,56],{"type":31,"name":32,"description":33,"armGroupLabels":34},"DRUG","Zanubrutinib","Given PO",[35,36],"Arm 1 (zanubrutinib)","Arm 2 (zanubrutinib and sonrotoclax)",{"type":31,"name":38,"description":33,"armGroupLabels":39},"Sonrotoclax",[36],{"type":41,"name":42,"description":43,"armGroupLabels":44,"otherNames":45},"PROCEDURE","Computed Tomography","Undergo CT scan",[35,36],[46,47],"CT Scan","Cat Scan",{"type":41,"name":49,"description":50,"armGroupLabels":51},"Bone Marrow Aspiration","Undergo bone marrow aspiration",[35,36],{"type":41,"name":53,"description":54,"armGroupLabels":55},"Biospecimen Collection","Undergo blood sample collection",[35,36],{"type":14,"name":57,"description":58,"armGroupLabels":59},"Survey Administration","Ancillary studies",[35,36],[61],{"measure":62,"description":63,"timeFrame":64},"Progression free survival (PFS)","From initial randomization date until the earlier of disease progression or death from any cause. PFS estimates for zanubrutinib plus sonrotoclax therapy to continuous Zanubrutinib.","From initial randomization date until the earlier of disease progression or death from any cause, up to 10 years",[],"ALL","65 Years",null,{"inclusion":70,"exclusion":112,"raw_text":113},[71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,107,108,109,110,111],"STEP 0: This bone marrow or peripheral blood submission to Adaptive is mandatory prior to registration\u002Frandomization for real-time identification of the clone needed for MRD testing. The bone marrow sample should be from the first aspiration (i.e., first pull). Aspirate needle should be redirected if needed to get first pull bone marrow aspirate. It should be obtained as soon after pre-registration as possible to confirm registration eligibility","STEP 0: Patients must be diagnosed with CLL\u002FSLL according to International Workshop on Chronic Lymphocytic Leukemia (IWCLL) 2018 criteria that includes all of the following:","≥ 5 x10\\^9 \u002FL B lymphocytes (5000\u002FμL) in the peripheral blood (CLL) or a lymph node biopsy demonstrating SLL with the below immunophenotype (SLL)","On morphologic review, the leukemic cells must be small mature lymphocytes","Immunophenotype of CLL cells (performed locally) must reveal a clonal B-cell population, which coexpress the B cell surface markers of CD19 and CD20, as well as the T-cell antigen CD5. Patients with bright surface immunoglobulin expression or lack of CD23 expression in \\> 10% of cells must lack t(11;14) translocation by interphase cytogenetics","STEP 0: Patients must meet criteria for treatment as defined by IWCLL 2018 guidelines which includes at least one of the following criteria:","Evidence of marrow failure as manifested by the development or worsening of anemia or thrombocytopenia (not attributable to autoimmune hemolytic anemia or thrombocytopenia), typically hemoglobin (Hb) \\\u003C 10 g\u002FdL, platelet count \\\u003C 100,000\u002Fmm\\^3","Massive (\\> 6 cm below the costal margin), progressive or symptomatic splenomegaly","Massive nodes (ie, \\> 10 cm in longest diameter) or progressive or symptomatic lymphadenopathy","Autoimmune anemia and\u002For thrombocytopenia that is poorly responsive to standard therapy","Constitutional symptoms, which include any of the following:","Unintentional weight loss of ≥ 10% within the previous 6 months","Significant fatigue (ie. Eastern Cooperative Oncology Group \\[ECOG\\] performance status \\[PS\\] ≥ 2)","Fevers \\>100.5 °F or 38.0°C for 2 weeks or more without evidence of infection","Night sweats \\> 1 month without evidence of infection","STEP 0: Patients must not have had prior therapy for CLL (except palliative steroids or treatment of autoimmune complications of CLL with rituximab or steroids)","STEP 0: Treatment with rituximab and\u002For high-dose corticosteroids for autoimmune complications of CLL must be completed prior to enrollment. Palliative steroids must be at a dose not higher than 20 mg\u002Fday of prednisone or equivalent corticosteroid at the time of registration","STEP 0: Age ≥ 65 years","STEP 0: ECOG performance status ≤ 2","STEP 0: Patients with known HIV infection on effective anti-retroviral therapy with undetectable viral load within 6 months prior to registration are eligible for this trial","STEP 0: For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated","STEP 0: Patients with a history of hepatitis C virus (HCV), infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load","STEP 0: Patients must not be receiving active systemic anticoagulation with warfarin. Patients must be off warfarin therapy for at least 5 half-lives washout and with normal INR prior to enrollment","STEP 0: Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients must be class 2B or better.","STEP 0: No patients with a history of a severe bleeding disorder or a history of hemorrhagic stroke or intracranial hemorrhage","STEP 0: No patients with known active progressive central nervous system (CNS) disease","STEP 0: No known medical condition causing an inability to swallow oral formulations of agents","STEP 1: The adaptive report confirming a measurable and trackable B cell clone","STEP 1: Patients may not have had major surgery within 7 days of enrollment, or minor surgery within 5 days of enrollment. Examples of minor surgery include dental surgery, insertion of a venous access device, skin biopsy, or aspiration of a joint. The decision about whether a surgery is major or minor can be made at the discretion of the treating physician","STEP 1: No patients with ongoing active fungal, bacterial or viral infection requiring systemic therapy except those described in the protocol document","STEP 1: Patients must not require more than 20 mg prednisone or equivalent corticosteroid daily","STEP 1: Patients must not have uncontrolled active systemic infection requiring intravenous antibiotics","STEP 1: Patients must not have continued requirement for therapy with a strong CYP3A4\u002F5 inhibitor or inducer. Any such inhibitor or inducer must have been discontinued at least 14 days or 5 half-lives (whichever is shorter) before the first dose of study drug","STEP 1: Absolute neutrophil count (ANC) ≥ 1,000\u002Fmm3 unless due to marrow involvement","STEP 1: Platelet count ≥ 30,000\u002Fmm3","STEP 1: Total bilirubin ≤ 1.5 x upper limit of normal (ULN) (unless due to liver involvement, hemolysis or Gilbert's disease)","STEP 1: Aspartate aminotransferase (AST)(serum glutamic oxaloacetic transaminase \\[SGOT\\])\u002F alanine aminotransferase (ALT) (serum glutamic pyruvic transaminase \\[SGPT\\]) ≤ 3.0 x upper limit of normal (ULN) unless due to disease infiltration of the liver","STEP 1: Calculated (calc.) creatinine clearance by Chronic Kidney Disease Epidemiology Collaboration equation (CKD-EPI) ≥ 30 mL\u002Fmin","STEP 1: Urine protein to creatinine ratio \\\u003C 1 or urine protein ≤ 1+","STEP 2: Detectable MRD ≥ 10 residual clonal cells per million nucleated cells in peripheral blood at the C15 restaging evaluation from ClonoSEQ","STEP 2: Response of PR, PR-L, CR, CCR or CRi to zanubrutinib sonrotoclax therapy",[],"Inclusion Criteria:\n\n* STEP 0: This bone marrow or peripheral blood submission to Adaptive is mandatory prior to registration\u002Frandomization for real-time identification of the clone needed for MRD testing. The bone marrow sample should be from the first aspiration (i.e., first pull). Aspirate needle should be redirected if needed to get first pull bone marrow aspirate. It should be obtained as soon after pre-registration as possible to confirm registration eligibility\n* STEP 0: Patients must be diagnosed with CLL\u002FSLL according to International Workshop on Chronic Lymphocytic Leukemia (IWCLL) 2018 criteria that includes all of the following:\n\n  * ≥ 5 x10\\^9 \u002FL B lymphocytes (5000\u002FμL) in the peripheral blood (CLL) or a lymph node biopsy demonstrating SLL with the below immunophenotype (SLL)\n  * On morphologic review, the leukemic cells must be small mature lymphocytes\n  * Immunophenotype of CLL cells (performed locally) must reveal a clonal B-cell population, which coexpress the B cell surface markers of CD19 and CD20, as well as the T-cell antigen CD5. Patients with bright surface immunoglobulin expression or lack of CD23 expression in \\> 10% of cells must lack t(11;14) translocation by interphase cytogenetics\n* STEP 0: Patients must meet criteria for treatment as defined by IWCLL 2018 guidelines which includes at least one of the following criteria:\n\n  * Evidence of marrow failure as manifested by the development or worsening of anemia or thrombocytopenia (not attributable to autoimmune hemolytic anemia or thrombocytopenia), typically hemoglobin (Hb) \\\u003C 10 g\u002FdL, platelet count \\\u003C 100,000\u002Fmm\\^3\n  * Massive (\\> 6 cm below the costal margin), progressive or symptomatic splenomegaly\n  * Massive nodes (ie, \\> 10 cm in longest diameter) or progressive or symptomatic lymphadenopathy\n  * Autoimmune anemia and\u002For thrombocytopenia that is poorly responsive to standard therapy\n  * Constitutional symptoms, which include any of the following:\n\n    * Unintentional weight loss of ≥ 10% within the previous 6 months\n    * Significant fatigue (ie. Eastern Cooperative Oncology Group \\[ECOG\\] performance status \\[PS\\] ≥ 2)\n    * Fevers \\>100.5 °F or 38.0°C for 2 weeks or more without evidence of infection\n    * Night sweats \\> 1 month without evidence of infection\n* STEP 0: Patients must not have had prior therapy for CLL (except palliative steroids or treatment of autoimmune complications of CLL with rituximab or steroids)\n* STEP 0: Treatment with rituximab and\u002For high-dose corticosteroids for autoimmune complications of CLL must be completed prior to enrollment. Palliative steroids must be at a dose not higher than 20 mg\u002Fday of prednisone or equivalent corticosteroid at the time of registration\n* STEP 0: Age ≥ 65 years\n* STEP 0: ECOG performance status ≤ 2\n* STEP 0: Patients with known HIV infection on effective anti-retroviral therapy with undetectable viral load within 6 months prior to registration are eligible for this trial\n* STEP 0: For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated\n* STEP 0: Patients with a history of hepatitis C virus (HCV), infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load\n* STEP 0: Patients must not be receiving active systemic anticoagulation with warfarin. Patients must be off warfarin therapy for at least 5 half-lives washout and with normal INR prior to enrollment\n* STEP 0: Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients must be class 2B or better.\n\nPatients with acute cardiac events within 6 months prior to registration should be carefully evaluated for their suitability for enrollment\n\n* STEP 0: No patients with a history of a severe bleeding disorder or a history of hemorrhagic stroke or intracranial hemorrhage\n* STEP 0: No patients with known active progressive central nervous system (CNS) disease\n* STEP 0: No known medical condition causing an inability to swallow oral formulations of agents\n* STEP 1: The adaptive report confirming a measurable and trackable B cell clone\n* STEP 1: Patients may not have had major surgery within 7 days of enrollment, or minor surgery within 5 days of enrollment. Examples of minor surgery include dental surgery, insertion of a venous access device, skin biopsy, or aspiration of a joint. The decision about whether a surgery is major or minor can be made at the discretion of the treating physician\n* STEP 1: No patients with ongoing active fungal, bacterial or viral infection requiring systemic therapy except those described in the protocol document\n* STEP 1: Patients must not require more than 20 mg prednisone or equivalent corticosteroid daily\n* STEP 1: Patients must not have uncontrolled active systemic infection requiring intravenous antibiotics\n* STEP 1: Patients must not have continued requirement for therapy with a strong CYP3A4\u002F5 inhibitor or inducer. Any such inhibitor or inducer must have been discontinued at least 14 days or 5 half-lives (whichever is shorter) before the first dose of study drug\n* STEP 1: Absolute neutrophil count (ANC) ≥ 1,000\u002Fmm3 unless due to marrow involvement\n* STEP 1: Platelet count ≥ 30,000\u002Fmm3\n* STEP 1: Total bilirubin ≤ 1.5 x upper limit of normal (ULN) (unless due to liver involvement, hemolysis or Gilbert's disease)\n* STEP 1: Aspartate aminotransferase (AST)(serum glutamic oxaloacetic transaminase \\[SGOT\\])\u002F alanine aminotransferase (ALT) (serum glutamic pyruvic transaminase \\[SGPT\\]) ≤ 3.0 x upper limit of normal (ULN) unless due to disease infiltration of the liver\n* STEP 1: Calculated (calc.) creatinine clearance by Chronic Kidney Disease Epidemiology Collaboration equation (CKD-EPI) ≥ 30 mL\u002Fmin\n* STEP 1: Urine protein to creatinine ratio \\\u003C 1 or urine protein ≤ 1+\n* STEP 2: Detectable MRD ≥ 10 residual clonal cells per million nucleated cells in peripheral blood at the C15 restaging evaluation from ClonoSEQ\n* STEP 2: Response of PR, PR-L, CR, CCR or CRi to zanubrutinib sonrotoclax therapy",[115],"OLDER_ADULT",[117,135,148,162,175,189,199,212,222,232,242,252,266,276,286,299,308,321,333,339,350,361,371,381,391,401,411,421,427,437,443,453,463,473,483,493,505,516,523,532,542,552,565,573,585,597,609,616,626,637,643,651,658,664,674,682,692,702,712,726,736,746,756,769,779,791,801,811,821,833,843,853,863,873,881,892,902,912,922,929,935,945,958,967,981,991,1004,1017,1026,1036,1048,1058,1068,1078,1092,1105,1117,1127,1137,1147,1157,1167,1177,1184,1194,1204,1218,1231,1243,1253,1264,1274,1281,1288,1298,1308,1318,1325,1332,1339,1349,1360,1372,1382,1392,1402,1412,1426,1436,1449,1460,1474,1486,1499,1511,1521,1528,1535,1549,1562,1569,1575,1582,1589,1599,1605,1615,1621,1631,1641,1651,1662,1676,1687,1700,1710,1720,1729,1736,1747,1754,1768,1780,1791,1803,1810,1818,1829,1840,1850,1862,1870,1880,1891,1904,1912,1925,1938,1950,1961,1971,1981],{"facility":118,"status":8,"city":119,"state":120,"zip":121,"country":122,"contacts":123,"geoPoint":132},"Cedars-Sinai Medical Center","Los Angeles","California","90048","United States",[124,129],{"name":125,"role":126,"phone":127,"email":128},"Site Public Contact","CONTACT","310-423-2133","Cancer.trial.info@cshs.org",{"name":130,"role":131},"Justin M. Darrah","PRINCIPAL_INVESTIGATOR",{"lat":133,"lon":134},34.05223,-118.24368,{"facility":136,"status":8,"city":137,"state":120,"zip":138,"country":122,"contacts":139,"geoPoint":145},"Kaiser Permanente - Panorama City","Panorama City","91402",[140,143],{"name":125,"role":126,"phone":141,"email":142},"800-398-3996","clinical.trials@kp.org",{"name":144,"role":131},"Ashraf R. Aziz",{"lat":146,"lon":147},34.22473,-118.44981,{"facility":149,"status":8,"city":150,"state":151,"zip":152,"country":122,"contacts":153,"geoPoint":159},"Jupiter Medical Center","Jupiter","Florida","33458",[154,157],{"name":125,"role":126,"phone":155,"email":156},"561-263-5791","clinicaltrials@jupitermed.com",{"name":158,"role":131},"Ryan H. Devine",{"lat":160,"lon":161},26.93422,-80.09421,{"facility":163,"status":8,"city":164,"state":151,"zip":165,"country":122,"contacts":166,"geoPoint":172},"Mount Sinai Medical Center","Miami Beach","33140",[167,170],{"name":125,"role":126,"phone":168,"email":169},"305-674-2625","Yvonne.Enriquez@msmc.com",{"name":171,"role":131},"Jacqueline C. Barrientos",{"lat":173,"lon":174},25.79065,-80.13005,{"facility":176,"status":8,"city":177,"state":178,"zip":179,"country":122,"contacts":180,"geoPoint":186},"Saint Alphonsus Cancer Care Center-Boise","Boise","Idaho","83706",[181,184],{"name":125,"role":126,"phone":182,"email":183},"734-712-3671","stephanie.couch@stjoeshealth.org",{"name":185,"role":131},"Christopher M. Reynolds",{"lat":187,"lon":188},43.6135,-116.20345,{"facility":190,"status":8,"city":191,"state":178,"zip":192,"country":122,"contacts":193,"geoPoint":196},"Saint Alphonsus Cancer Care Center-Caldwell","Caldwell","83605",[194,195],{"name":125,"role":126,"phone":182,"email":183},{"name":185,"role":131},{"lat":197,"lon":198},43.66294,-116.68736,{"facility":200,"status":8,"city":201,"state":178,"zip":202,"country":122,"contacts":203,"geoPoint":209},"Kootenai Health - Coeur d'Alene","Coeur d'Alene","83814",[204,207],{"name":125,"role":126,"phone":205,"email":206},"406-969-6060","mccinfo@mtcancer.org",{"name":208,"role":131},"John M. Schallenkamp",{"lat":210,"lon":211},47.67768,-116.78047,{"facility":213,"status":8,"city":214,"state":178,"zip":215,"country":122,"contacts":216,"geoPoint":219},"Idaho Urologic Institute-Meridian","Meridian","83642",[217,218],{"name":125,"role":126,"phone":182,"email":183},{"name":185,"role":131},{"lat":220,"lon":221},43.61211,-116.39151,{"facility":223,"status":8,"city":224,"state":178,"zip":225,"country":122,"contacts":226,"geoPoint":229},"Saint Alphonsus Cancer Care Center-Nampa","Nampa","83687",[227,228],{"name":125,"role":126,"phone":205,"email":206},{"name":185,"role":131},{"lat":230,"lon":231},43.54072,-116.56346,{"facility":233,"status":8,"city":234,"state":178,"zip":235,"country":122,"contacts":236,"geoPoint":239},"Kootenai Clinic Cancer Services - Post Falls","Post Falls","83854",[237,238],{"name":125,"role":126,"phone":205,"email":206},{"name":208,"role":131},{"lat":240,"lon":241},47.71796,-116.95159,{"facility":243,"status":8,"city":244,"state":178,"zip":245,"country":122,"contacts":246,"geoPoint":249},"Kootenai Clinic Cancer Services - Sandpoint","Sandpoint","83864",[247,248],{"name":125,"role":126,"phone":205,"email":206},{"name":208,"role":131},{"lat":250,"lon":251},48.27659,-116.55325,{"facility":253,"status":8,"city":254,"state":255,"zip":256,"country":122,"contacts":257,"geoPoint":263},"Illinois CancerCare-Bloomington","Bloomington","Illinois","61704",[258,261],{"name":125,"role":126,"phone":259,"email":260},"309-243-3605","andersonj@illinoiscancercare.com",{"name":262,"role":131},"Bryan A. Faller",{"lat":264,"lon":265},40.4842,-88.99369,{"facility":267,"status":8,"city":268,"state":255,"zip":269,"country":122,"contacts":270,"geoPoint":273},"Illinois CancerCare-Canton","Canton","61520",[271,272],{"name":125,"role":126,"phone":259,"email":260},{"name":262,"role":131},{"lat":274,"lon":275},40.55809,-90.03512,{"facility":277,"status":8,"city":278,"state":255,"zip":279,"country":122,"contacts":280,"geoPoint":283},"Illinois CancerCare-Carthage","Carthage","62321",[281,282],{"name":125,"role":126,"phone":259,"email":260},{"name":262,"role":131},{"lat":284,"lon":285},40.41643,-91.13625,{"facility":287,"status":8,"city":288,"state":255,"zip":289,"country":122,"contacts":290,"geoPoint":296},"Northwestern University","Chicago","60611",[291,294],{"name":125,"role":126,"phone":292,"email":293},"312-695-1301","cancer@northwestern.edu",{"name":295,"role":131},"Shuo Ma",{"lat":297,"lon":298},41.85003,-87.65005,{"facility":300,"status":8,"city":288,"state":255,"zip":301,"country":122,"contacts":302,"geoPoint":307},"University of Illinois","60612",[303,305],{"name":125,"role":126,"phone":304},"312-355-3046",{"name":306,"role":131},"Carlos Galvez",{"lat":297,"lon":298},{"facility":309,"status":8,"city":310,"state":255,"zip":311,"country":122,"contacts":312,"geoPoint":318},"Carle at The Riverfront","Danville","61832",[313,316],{"name":125,"role":126,"phone":314,"email":315},"800-446-5532","Research@Carle.com",{"name":317,"role":131},"Suparna Mantha",{"lat":319,"lon":320},40.12448,-87.63002,{"facility":322,"status":8,"city":323,"state":255,"zip":324,"country":122,"contacts":325,"geoPoint":330},"Cancer Care Specialists of Illinois - Decatur","Decatur","62526",[326,329],{"name":125,"role":126,"phone":327,"email":328},"217-876-4762","morganthaler.jodi@mhsil.com",{"name":262,"role":131},{"lat":331,"lon":332},39.84031,-88.9548,{"facility":334,"status":8,"city":323,"state":255,"zip":324,"country":122,"contacts":335,"geoPoint":338},"Decatur Memorial Hospital",[336,337],{"name":125,"role":126,"phone":327,"email":328},{"name":262,"role":131},{"lat":331,"lon":332},{"facility":340,"status":8,"city":341,"state":255,"zip":342,"country":122,"contacts":343,"geoPoint":347},"Illinois CancerCare-Dixon","Dixon","61021",[344,346],{"name":125,"role":126,"phone":345},"815-285-7800",{"name":262,"role":131},{"lat":348,"lon":349},41.83892,-89.47955,{"facility":351,"status":8,"city":352,"state":255,"zip":353,"country":122,"contacts":354,"geoPoint":358},"Carle Physician Group-Effingham","Effingham","62401",[355,357],{"name":125,"role":126,"phone":314,"email":356},"Research@carle.com",{"name":317,"role":131},{"lat":359,"lon":360},39.12004,-88.54338,{"facility":362,"status":8,"city":363,"state":255,"zip":364,"country":122,"contacts":365,"geoPoint":368},"Illinois CancerCare-Eureka","Eureka","61530",[366,367],{"name":125,"role":126,"phone":259,"email":260},{"name":262,"role":131},{"lat":369,"lon":370},40.72143,-89.27286,{"facility":372,"status":8,"city":373,"state":255,"zip":374,"country":122,"contacts":375,"geoPoint":378},"Illinois CancerCare-Galesburg","Galesburg","61401",[376,377],{"name":125,"role":126,"phone":259,"email":260},{"name":262,"role":131},{"lat":379,"lon":380},40.94782,-90.37124,{"facility":382,"status":8,"city":383,"state":255,"zip":384,"country":122,"contacts":385,"geoPoint":388},"Illinois CancerCare-Kewanee Clinic","Kewanee","61443",[386,387],{"name":125,"role":126,"phone":259,"email":260},{"name":262,"role":131},{"lat":389,"lon":390},41.24559,-89.92483,{"facility":392,"status":8,"city":393,"state":255,"zip":394,"country":122,"contacts":395,"geoPoint":398},"Illinois CancerCare-Macomb","Macomb","61455",[396,397],{"name":125,"role":126,"phone":259,"email":260},{"name":262,"role":131},{"lat":399,"lon":400},40.45921,-90.6718,{"facility":402,"status":8,"city":403,"state":255,"zip":404,"country":122,"contacts":405,"geoPoint":408},"Carle Physician Group-Mattoon\u002FCharleston","Mattoon","61938",[406,407],{"name":125,"role":126,"phone":314,"email":356},{"name":317,"role":131},{"lat":409,"lon":410},39.48309,-88.37283,{"facility":412,"status":8,"city":413,"state":255,"zip":414,"country":122,"contacts":415,"geoPoint":418},"Carle BroMenn Medical Center","Normal","61761",[416,417],{"name":125,"role":126,"phone":314,"email":315},{"name":317,"role":131},{"lat":419,"lon":420},40.5142,-88.99063,{"facility":422,"status":8,"city":413,"state":255,"zip":414,"country":122,"contacts":423,"geoPoint":426},"Carle Cancer Institute Normal",[424,425],{"name":125,"role":126,"phone":314,"email":315},{"name":317,"role":131},{"lat":419,"lon":420},{"facility":428,"status":8,"city":429,"state":255,"zip":430,"country":122,"contacts":431,"geoPoint":434},"Cancer Care Center of O'Fallon","O'Fallon","62269",[432,433],{"name":125,"role":126,"phone":327,"email":328},{"name":262,"role":131},{"lat":435,"lon":436},38.59227,-89.91121,{"facility":438,"status":8,"city":429,"state":255,"zip":430,"country":122,"contacts":439,"geoPoint":442},"HSHS Saint Elizabeth's Hospital",[440,441],{"name":125,"role":126,"phone":327,"email":328},{"name":262,"role":131},{"lat":435,"lon":436},{"facility":444,"status":8,"city":445,"state":255,"zip":446,"country":122,"contacts":447,"geoPoint":450},"Illinois CancerCare-Ottawa Clinic","Ottawa","61350",[448,449],{"name":125,"role":126,"phone":259,"email":260},{"name":262,"role":131},{"lat":451,"lon":452},41.34559,-88.84258,{"facility":454,"status":8,"city":455,"state":255,"zip":456,"country":122,"contacts":457,"geoPoint":460},"Illinois CancerCare-Pekin","Pekin","61554",[458,459],{"name":125,"role":126,"phone":259,"email":260},{"name":262,"role":131},{"lat":461,"lon":462},40.56754,-89.64066,{"facility":464,"status":8,"city":465,"state":255,"zip":466,"country":122,"contacts":467,"geoPoint":470},"Illinois CancerCare-Peoria","Peoria","61615",[468,469],{"name":125,"role":126,"phone":259,"email":260},{"name":262,"role":131},{"lat":471,"lon":472},40.69365,-89.58899,{"facility":474,"status":8,"city":475,"state":255,"zip":476,"country":122,"contacts":477,"geoPoint":480},"Illinois CancerCare-Peru","Peru","61354",[478,479],{"name":125,"role":126,"phone":259,"email":260},{"name":262,"role":131},{"lat":481,"lon":482},41.32753,-89.12897,{"facility":484,"status":8,"city":485,"state":255,"zip":486,"country":122,"contacts":487,"geoPoint":490},"Illinois CancerCare-Princeton","Princeton","61356",[488,489],{"name":125,"role":126,"phone":259,"email":260},{"name":262,"role":131},{"lat":491,"lon":492},41.36809,-89.46481,{"facility":494,"status":8,"city":495,"state":255,"zip":430,"country":122,"contacts":496,"geoPoint":502},"Memorial Hospital East","Shiloh",[497,500],{"name":125,"role":126,"phone":498,"email":499},"314-747-9912","dschwab@wustl.edu",{"name":501,"role":131},"Dilan A. Patel",{"lat":503,"lon":504},38.56144,-89.89732,{"facility":506,"status":8,"city":507,"state":255,"zip":508,"country":122,"contacts":509,"geoPoint":513},"Southern Illinois University School of Medicine","Springfield","62702",[510,512],{"name":125,"role":126,"phone":511},"217-545-7929",{"name":262,"role":131},{"lat":514,"lon":515},39.80172,-89.64371,{"facility":517,"status":8,"city":507,"state":255,"zip":508,"country":122,"contacts":518,"geoPoint":522},"Springfield Clinic",[519,521],{"name":125,"role":126,"phone":520},"800-444-7541",{"name":262,"role":131},{"lat":514,"lon":515},{"facility":524,"status":8,"city":507,"state":255,"zip":525,"country":122,"contacts":526,"geoPoint":531},"Springfield Memorial Hospital","62781",[527,530],{"name":125,"role":126,"phone":528,"email":529},"217-528-7541","pallante.beth@mhsil.com",{"name":262,"role":131},{"lat":514,"lon":515},{"facility":533,"status":8,"city":534,"state":255,"zip":535,"country":122,"contacts":536,"geoPoint":539},"Carle Cancer Center","Urbana","61801",[537,538],{"name":125,"role":126,"phone":314,"email":356},{"name":317,"role":131},{"lat":540,"lon":541},40.11059,-88.20727,{"facility":543,"status":8,"city":544,"state":255,"zip":545,"country":122,"contacts":546,"geoPoint":549},"Illinois CancerCare - Washington","Washington","61571",[547,548],{"name":125,"role":126,"phone":259,"email":260},{"name":262,"role":131},{"lat":550,"lon":551},40.70365,-89.40731,{"facility":553,"status":8,"city":554,"state":555,"zip":556,"country":122,"contacts":557,"geoPoint":562},"Mary Greeley Medical Center","Ames","Iowa","50010",[558,560],{"name":125,"role":126,"phone":559},"515-956-4132",{"name":561,"role":131},"Joseph J. Merchant",{"lat":563,"lon":564},42.03471,-93.61994,{"facility":566,"status":8,"city":554,"state":555,"zip":556,"country":122,"contacts":567,"geoPoint":572},"McFarland Clinic - Ames",[568,571],{"name":125,"role":126,"phone":569,"email":570},"515-239-4734","ksoder@mcfarlandclinic.com",{"name":561,"role":131},{"lat":563,"lon":564},{"facility":574,"status":8,"city":575,"state":555,"zip":576,"country":122,"contacts":577,"geoPoint":582},"UI Health Care Mission Cancer and Blood - Ankeny Clinic","Ankeny","50023",[578,580],{"name":125,"role":126,"phone":579},"515-241-3305",{"name":581,"role":131},"Seema Harichand-Herdt",{"lat":583,"lon":584},41.72971,-93.60577,{"facility":586,"status":8,"city":587,"state":555,"zip":588,"country":122,"contacts":589,"geoPoint":594},"Saint Anthony Regional Hospital","Carroll","51401",[590,593],{"name":125,"role":126,"phone":591,"email":592},"515-689-7658","sbenson@iora.org",{"name":581,"role":131},{"lat":595,"lon":596},42.06582,-94.86693,{"facility":598,"status":8,"city":599,"state":555,"zip":600,"country":122,"contacts":601,"geoPoint":606},"Mercy Hospital","Cedar Rapids","52403",[602,604],{"name":125,"role":126,"phone":603},"319-365-4673",{"name":605,"role":131},"Deborah W. Wilbur",{"lat":607,"lon":608},42.00833,-91.64407,{"facility":610,"status":8,"city":599,"state":555,"zip":600,"country":122,"contacts":611,"geoPoint":615},"Oncology Associates at Mercy Medical Center",[612,614],{"name":125,"role":126,"phone":613},"319-363-2690",{"name":605,"role":131},{"lat":607,"lon":608},{"facility":617,"status":8,"city":618,"state":555,"zip":619,"country":122,"contacts":620,"geoPoint":623},"UI Health Care Mission Cancer and Blood - West Des Moines Clinic","Clive","50325",[621,622],{"name":125,"role":126,"phone":579},{"name":581,"role":131},{"lat":624,"lon":625},41.60304,-93.72411,{"facility":627,"status":8,"city":628,"state":555,"zip":629,"country":122,"contacts":630,"geoPoint":634},"Iowa Methodist Medical Center","Des Moines","50309",[631,633],{"name":125,"role":126,"phone":632},"515-241-6727",{"name":581,"role":131},{"lat":635,"lon":636},41.60054,-93.60911,{"facility":638,"status":8,"city":628,"state":555,"zip":629,"country":122,"contacts":639,"geoPoint":642},"UI Health Care Mission Cancer and Blood - Des Moines Clinic",[640,641],{"name":125,"role":126,"phone":579},{"name":581,"role":131},{"lat":635,"lon":636},{"facility":644,"status":8,"city":628,"state":555,"zip":645,"country":122,"contacts":646,"geoPoint":650},"Broadlawns Medical Center","50314",[647,649],{"name":125,"role":126,"phone":648},"515-282-2200",{"name":581,"role":131},{"lat":635,"lon":636},{"facility":652,"status":8,"city":628,"state":555,"zip":645,"country":122,"contacts":653,"geoPoint":657},"Mercy Medical Center - Des Moines",[654,655],{"name":125,"role":126,"phone":579},{"name":656,"role":131},"Richard L. Deming",{"lat":635,"lon":636},{"facility":659,"status":8,"city":628,"state":555,"zip":645,"country":122,"contacts":660,"geoPoint":663},"UI Health Care Mission Cancer and Blood - Laurel Clinic",[661,662],{"name":125,"role":126,"phone":579},{"name":581,"role":131},{"lat":635,"lon":636},{"facility":665,"status":8,"city":666,"state":555,"zip":667,"country":122,"contacts":668,"geoPoint":671},"McFarland Clinic - Trinity Cancer Center","Fort Dodge","50501",[669,670],{"name":125,"role":126,"phone":559},{"name":561,"role":131},{"lat":672,"lon":673},42.49747,-94.16802,{"facility":675,"status":8,"city":666,"state":555,"zip":667,"country":122,"contacts":676,"geoPoint":681},"UI Healthcare Mission Cancer and Blood - Fort Dodge",[677,680],{"name":125,"role":126,"phone":678,"email":679},"515-282-2921","trials@missioncancer.com",{"name":581,"role":131},{"lat":672,"lon":673},{"facility":683,"status":8,"city":684,"state":555,"zip":685,"country":122,"contacts":686,"geoPoint":689},"McFarland Clinic - Marshalltown","Marshalltown","50158",[687,688],{"name":125,"role":126,"phone":559},{"name":561,"role":131},{"lat":690,"lon":691},42.04943,-92.90798,{"facility":693,"status":8,"city":694,"state":555,"zip":695,"country":122,"contacts":696,"geoPoint":699},"UI Healthcare Mission Cancer and Blood - Pella","Pella","50219",[697,698],{"name":125,"role":126,"phone":678,"email":679},{"name":581,"role":131},{"lat":700,"lon":701},41.40805,-92.91631,{"facility":703,"status":8,"city":704,"state":555,"zip":705,"country":122,"contacts":706,"geoPoint":709},"UI Health Care Mission Cancer and Blood - Waukee Clinic","Waukee","50263",[707,708],{"name":125,"role":126,"phone":579},{"name":581,"role":131},{"lat":710,"lon":711},41.61166,-93.88523,{"facility":713,"status":8,"city":714,"state":715,"zip":716,"country":122,"contacts":717,"geoPoint":723},"Cancer Center of Kansas - Chanute","Chanute","Kansas","66720",[718,721],{"name":125,"role":126,"phone":719,"email":720},"316-291-4774","research@viachristi.org",{"name":722,"role":131},"Dennis F. Moore",{"lat":724,"lon":725},37.67921,-95.4572,{"facility":727,"status":8,"city":728,"state":715,"zip":729,"country":122,"contacts":730,"geoPoint":733},"Cancer Center of Kansas - Dodge City","Dodge City","67801",[731,732],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":734,"lon":735},37.7528,-100.01708,{"facility":737,"status":8,"city":738,"state":715,"zip":739,"country":122,"contacts":740,"geoPoint":743},"Cancer Center of Kansas - El Dorado","El Dorado","67042",[741,742],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":744,"lon":745},37.81724,-96.86225,{"facility":747,"status":8,"city":748,"state":715,"zip":749,"country":122,"contacts":750,"geoPoint":753},"Cancer Center of Kansas-Independence","Independence","67301",[751,752],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":754,"lon":755},37.22424,-95.70831,{"facility":757,"status":8,"city":758,"state":715,"zip":759,"country":122,"contacts":760,"geoPoint":766},"University of Kansas Cancer Center","Kansas City","66160",[761,764],{"name":125,"role":126,"phone":762,"email":763},"913-588-3671","KUCC_Navigation@kumc.edu",{"name":765,"role":131},"Marc S. Hoffmann",{"lat":767,"lon":768},39.11417,-94.62746,{"facility":770,"status":8,"city":771,"state":715,"zip":772,"country":122,"contacts":773,"geoPoint":776},"Cancer Center of Kansas-Kingman","Kingman","67068",[774,775],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":777,"lon":778},37.64585,-98.11367,{"facility":780,"status":8,"city":781,"state":715,"zip":782,"country":122,"contacts":783,"geoPoint":788},"Lawrence Memorial Hospital","Lawrence","66044",[784,787],{"name":125,"role":126,"phone":785,"email":786},"785-505-2800","Stephanie.Norris@LMH.ORG",{"name":765,"role":131},{"lat":789,"lon":790},38.97167,-95.23525,{"facility":792,"status":8,"city":793,"state":715,"zip":794,"country":122,"contacts":795,"geoPoint":798},"Cancer Center of Kansas-Liberal","Liberal","67905",[796,797],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":799,"lon":800},37.04308,-100.921,{"facility":802,"status":8,"city":803,"state":715,"zip":804,"country":122,"contacts":805,"geoPoint":808},"Cancer Center of Kansas - McPherson","McPherson","67460",[806,807],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":809,"lon":810},38.37084,-97.66421,{"facility":812,"status":8,"city":813,"state":715,"zip":814,"country":122,"contacts":815,"geoPoint":818},"Cancer Center of Kansas - Newton","Newton","67114",[816,817],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":819,"lon":820},38.04668,-97.34504,{"facility":822,"status":8,"city":823,"state":715,"zip":824,"country":122,"contacts":825,"geoPoint":830},"The University of Kansas Cancer Center - Olathe","Olathe","66061",[826,829],{"name":125,"role":126,"phone":827,"email":828},"913-588-1569","OlatheCCResearch@kumc.edu",{"name":765,"role":131},{"lat":831,"lon":832},38.8814,-94.81913,{"facility":834,"status":8,"city":835,"state":715,"zip":836,"country":122,"contacts":837,"geoPoint":840},"University of Kansas Cancer Center-Overland Park","Overland Park","66210",[838,839],{"name":125,"role":126,"phone":762,"email":763},{"name":765,"role":131},{"lat":841,"lon":842},38.98223,-94.67079,{"facility":844,"status":8,"city":845,"state":715,"zip":846,"country":122,"contacts":847,"geoPoint":850},"Cancer Center of Kansas - Parsons","Parsons","67357",[848,849],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":851,"lon":852},37.34034,-95.26108,{"facility":854,"status":8,"city":855,"state":715,"zip":856,"country":122,"contacts":857,"geoPoint":860},"Cancer Center of Kansas - Pratt","Pratt","67124",[858,859],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":861,"lon":862},37.64391,-98.73759,{"facility":864,"status":8,"city":865,"state":715,"zip":866,"country":122,"contacts":867,"geoPoint":870},"Cancer Center of Kansas - Salina","Salina","67401",[868,869],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":871,"lon":872},38.84028,-97.61142,{"facility":874,"status":8,"city":865,"state":715,"zip":866,"country":122,"contacts":875,"geoPoint":880},"Salina Regional Health Center",[876,879],{"name":125,"role":126,"phone":877,"email":878},"785-452-7038","mleepers@srhc.com",{"name":765,"role":131},{"lat":871,"lon":872},{"facility":882,"status":8,"city":883,"state":715,"zip":884,"country":122,"contacts":885,"geoPoint":889},"University of Kansas Health System Saint Francis Campus","Topeka","66606",[886,888],{"name":125,"role":126,"phone":887},"785-295-8000",{"name":765,"role":131},{"lat":890,"lon":891},39.04833,-95.67804,{"facility":893,"status":8,"city":894,"state":715,"zip":895,"country":122,"contacts":896,"geoPoint":899},"Cancer Center of Kansas - Wellington","Wellington","67152",[897,898],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":900,"lon":901},37.2653,-97.37171,{"facility":903,"status":8,"city":904,"state":715,"zip":905,"country":122,"contacts":906,"geoPoint":909},"University of Kansas Hospital-Westwood Cancer Center","Westwood","66205",[907,908],{"name":125,"role":126,"phone":762,"email":763},{"name":765,"role":131},{"lat":910,"lon":911},39.04056,-94.6169,{"facility":913,"status":8,"city":914,"state":715,"zip":915,"country":122,"contacts":916,"geoPoint":919},"Cancer Center of Kansas-Wichita Medical Arts Tower","Wichita","67208",[917,918],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":920,"lon":921},37.69224,-97.33754,{"facility":923,"status":8,"city":914,"state":715,"zip":924,"country":122,"contacts":925,"geoPoint":928},"Ascension Via Christi Hospitals Wichita","67214",[926,927],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":920,"lon":921},{"facility":930,"status":8,"city":914,"state":715,"zip":924,"country":122,"contacts":931,"geoPoint":934},"Cancer Center of Kansas - Wichita",[932,933],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":920,"lon":921},{"facility":936,"status":8,"city":937,"state":715,"zip":938,"country":122,"contacts":939,"geoPoint":942},"Cancer Center of Kansas - Winfield","Winfield","67156",[940,941],{"name":125,"role":126,"phone":719,"email":720},{"name":722,"role":131},{"lat":943,"lon":944},37.23975,-96.99559,{"facility":946,"status":8,"city":947,"state":948,"zip":949,"country":122,"contacts":950,"geoPoint":955},"The James Graham Brown Cancer Center at University of Louisville","Louisville","Kentucky","40202",[951,953],{"name":125,"role":126,"phone":952},"502-562-3429",{"name":954,"role":131},"Hassaan Yasin",{"lat":956,"lon":957},38.25424,-85.75941,{"facility":959,"status":8,"city":947,"state":948,"zip":960,"country":122,"contacts":961,"geoPoint":966},"UofL Health Medical Center Northeast","40245",[962,965],{"name":125,"role":126,"phone":963,"email":964},"502-852-2755","ctoinfo@louisville.edu",{"name":954,"role":131},{"lat":956,"lon":957},{"facility":968,"status":8,"city":969,"state":970,"zip":971,"country":122,"contacts":972,"geoPoint":978},"MaineHealth Maine Medical Center - Portland","Portland","Maine","04102",[973,976],{"name":125,"role":126,"phone":974,"email":975},"207-396-8670","clinicalresearch@mainehealth.org",{"name":977,"role":131},"Andrew Rogers",{"lat":979,"lon":980},43.65737,-70.2589,{"facility":982,"status":8,"city":983,"state":970,"zip":984,"country":122,"contacts":985,"geoPoint":988},"MaineHealth Cancer Care and IV Therapy - South Portland","South Portland","04106",[986,987],{"name":125,"role":126,"phone":974,"email":975},{"name":977,"role":131},{"lat":989,"lon":990},43.64147,-70.24088,{"facility":992,"status":8,"city":993,"state":994,"zip":995,"country":122,"contacts":996,"geoPoint":1001},"Dana-Farber Cancer Institute","Boston","Massachusetts","02215",[997,999],{"name":125,"role":126,"phone":998},"877-442-3324",{"name":1000,"role":131},"Jennifer R. Brown",{"lat":1002,"lon":1003},42.35843,-71.05977,{"facility":1005,"status":8,"city":1006,"state":1007,"zip":1008,"country":122,"contacts":1009,"geoPoint":1014},"Trinity Health IHA Medical Group Hematology Oncology - Brighton","Brighton","Michigan","48114",[1010,1013],{"name":125,"role":126,"phone":1011,"email":1012},"734-712-7251","MCRCwebsitecontactform@stjoeshealth.org",{"name":185,"role":131},{"lat":1015,"lon":1016},42.52948,-83.78022,{"facility":1018,"status":8,"city":268,"state":1007,"zip":1019,"country":122,"contacts":1020,"geoPoint":1023},"Trinity Health IHA Medical Group Hematology Oncology - Canton","48188",[1021,1022],{"name":125,"role":126,"phone":1011,"email":1012},{"name":185,"role":131},{"lat":1024,"lon":1025},42.30865,-83.48216,{"facility":1027,"status":8,"city":1028,"state":1007,"zip":1029,"country":122,"contacts":1030,"geoPoint":1033},"Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital","Chelsea","48118",[1031,1032],{"name":125,"role":126,"phone":1011,"email":1012},{"name":185,"role":131},{"lat":1034,"lon":1035},42.31807,-84.02181,{"facility":1037,"status":8,"city":1038,"state":1007,"zip":1039,"country":122,"contacts":1040,"geoPoint":1045},"University of Michigan Health - Sparrow Lansing","Lansing","48912",[1041,1044],{"name":125,"role":126,"phone":1042,"email":1043},"517-364-3712","harsha.trivedi@umhsparrow.org",{"name":185,"role":131},{"lat":1046,"lon":1047},42.73253,-84.55553,{"facility":1049,"status":8,"city":1050,"state":1007,"zip":1051,"country":122,"contacts":1052,"geoPoint":1055},"Trinity Health Saint Mary Mercy Livonia Hospital","Livonia","48154",[1053,1054],{"name":125,"role":126,"phone":1011,"email":1012},{"name":185,"role":131},{"lat":1056,"lon":1057},42.36837,-83.35271,{"facility":1059,"status":8,"city":1060,"state":1007,"zip":1061,"country":122,"contacts":1062,"geoPoint":1065},"Trinity Health Saint Joseph Mercy Oakland Hospital","Pontiac","48341",[1063,1064],{"name":125,"role":126,"phone":1011,"email":1012},{"name":185,"role":131},{"lat":1066,"lon":1067},42.63892,-83.29105,{"facility":1069,"status":8,"city":1070,"state":1007,"zip":1071,"country":122,"contacts":1072,"geoPoint":1075},"Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus","Ypsilanti","48197",[1073,1074],{"name":125,"role":126,"phone":1011,"email":1012},{"name":185,"role":131},{"lat":1076,"lon":1077},42.24115,-83.61299,{"facility":1079,"status":8,"city":1080,"state":1081,"zip":1082,"country":122,"contacts":1083,"geoPoint":1089},"Sanford Joe Lueken Cancer Center","Bemidji","Minnesota","56601",[1084,1087],{"name":125,"role":126,"phone":1085,"email":1086},"218-333-5000","OncologyClinicalTrialsFargo@sanfordhealth.org",{"name":1088,"role":131},"Daniel Almquist",{"lat":1090,"lon":1091},47.47356,-94.88028,{"facility":1093,"status":8,"city":1094,"state":1081,"zip":1095,"country":122,"contacts":1096,"geoPoint":1102},"Essentia Health Saint Joseph's Medical Center","Brainerd","56401",[1097,1100],{"name":125,"role":126,"phone":1098,"email":1099},"218-786-3308","CancerTrials@EssentiaHealth.org",{"name":1101,"role":131},"Bret E. Friday",{"lat":1103,"lon":1104},46.35802,-94.20083,{"facility":598,"status":8,"city":1106,"state":1081,"zip":1107,"country":122,"contacts":1108,"geoPoint":1114},"Coon Rapids","55433",[1109,1112],{"name":125,"role":126,"phone":1110,"email":1111},"952-993-1517","mmcorc@healthpartners.com",{"name":1113,"role":131},"Yan Ji",{"lat":1115,"lon":1116},45.11997,-93.28773,{"facility":1118,"status":8,"city":1119,"state":1081,"zip":1120,"country":122,"contacts":1121,"geoPoint":1124},"Essentia Health - Deer River Clinic","Deer River","56636",[1122,1123],{"name":125,"role":126,"phone":1098,"email":1099},{"name":1101,"role":131},{"lat":1125,"lon":1126},47.333,-93.79272,{"facility":1128,"status":8,"city":1129,"state":1081,"zip":1130,"country":122,"contacts":1131,"geoPoint":1134},"Essentia Health Cancer Center","Duluth","55805",[1132,1133],{"name":125,"role":126,"phone":1098,"email":1099},{"name":1101,"role":131},{"lat":1135,"lon":1136},46.78327,-92.10658,{"facility":1138,"status":8,"city":1139,"state":1081,"zip":1140,"country":122,"contacts":1141,"geoPoint":1144},"Essentia Health Hibbing Clinic","Hibbing","55746",[1142,1143],{"name":125,"role":126,"phone":1098},{"name":1101,"role":131},{"lat":1145,"lon":1146},47.42715,-92.93769,{"facility":1148,"status":8,"city":1149,"state":1081,"zip":1150,"country":122,"contacts":1151,"geoPoint":1154},"Abbott-Northwestern Hospital","Minneapolis","55407",[1152,1153],{"name":125,"role":126,"phone":1110,"email":1111},{"name":1113,"role":131},{"lat":1155,"lon":1156},44.97997,-93.26384,{"facility":1158,"status":8,"city":1159,"state":1081,"zip":1160,"country":122,"contacts":1161,"geoPoint":1164},"Park Nicollet Clinic - Saint Louis Park","Saint Louis Park","55416",[1162,1163],{"name":125,"role":126,"phone":1110,"email":1111},{"name":1113,"role":131},{"lat":1165,"lon":1166},44.9483,-93.34801,{"facility":1168,"status":8,"city":1169,"state":1081,"zip":1170,"country":122,"contacts":1171,"geoPoint":1174},"Regions Hospital","Saint Paul","55101",[1172,1173],{"name":125,"role":126,"phone":1110,"email":1111},{"name":1113,"role":131},{"lat":1175,"lon":1176},44.94441,-93.09327,{"facility":1178,"status":8,"city":1169,"state":1081,"zip":1179,"country":122,"contacts":1180,"geoPoint":1183},"United Hospital","55102",[1181,1182],{"name":125,"role":126,"phone":1110,"email":1111},{"name":1113,"role":131},{"lat":1175,"lon":1176},{"facility":1185,"status":8,"city":1186,"state":1081,"zip":1187,"country":122,"contacts":1188,"geoPoint":1191},"Essentia Health Sandstone","Sandstone","55072",[1189,1190],{"name":125,"role":126,"phone":1098,"email":1099},{"name":1101,"role":131},{"lat":1192,"lon":1193},46.13106,-92.86742,{"facility":1195,"status":8,"city":1196,"state":1081,"zip":1197,"country":122,"contacts":1198,"geoPoint":1201},"Essentia Health Virginia Clinic","Virginia","55792",[1199,1200],{"name":125,"role":126,"phone":1098,"email":1099},{"name":1101,"role":131},{"lat":1202,"lon":1203},47.52326,-92.53657,{"facility":1205,"status":8,"city":1206,"state":1207,"zip":1208,"country":122,"contacts":1209,"geoPoint":1215},"Baptist Memorial Hospital and Cancer Center-Desoto","Southhaven","Mississippi","38671",[1210,1213],{"name":125,"role":126,"phone":1211,"email":1212},"901-226-1366","BCCclintrials@bmhcc.org",{"name":1214,"role":131},"Muhammad Raza",{"lat":1216,"lon":1217},34.99176,-90.12759,{"facility":1219,"status":8,"city":1220,"state":1221,"zip":1222,"country":122,"contacts":1223,"geoPoint":1228},"Saint Francis Medical Center","Cape Girardeau","Missouri","63703",[1224,1227],{"name":125,"role":126,"phone":1225,"email":1226},"573-334-2230","sfmc@sfmc.net",{"name":262,"role":131},{"lat":1229,"lon":1230},37.30588,-89.51815,{"facility":1232,"status":8,"city":1233,"state":1221,"zip":1234,"country":122,"contacts":1235,"geoPoint":1240},"Siteman Cancer Center at Saint Peters Hospital","City of Saint Peters","63376",[1236,1239],{"name":125,"role":126,"phone":1237,"email":1238},"800-600-3606","info@siteman.wustl.edu",{"name":501,"role":131},{"lat":1241,"lon":1242},38.80033,-90.62651,{"facility":1244,"status":8,"city":1245,"state":1221,"zip":1246,"country":122,"contacts":1247,"geoPoint":1250},"Siteman Cancer Center at West County Hospital","Creve Coeur","63141",[1248,1249],{"name":125,"role":126,"phone":1237,"email":1238},{"name":501,"role":131},{"lat":1251,"lon":1252},38.66089,-90.42262,{"facility":1254,"status":8,"city":1255,"state":1221,"zip":1256,"country":122,"contacts":1257,"geoPoint":1261},"Parkland Health Center - Farmington","Farmington","63640",[1258,1260],{"name":125,"role":126,"phone":1259},"314-996-5569",{"name":262,"role":131},{"lat":1262,"lon":1263},37.78088,-90.42179,{"facility":1265,"status":8,"city":758,"state":1221,"zip":1266,"country":122,"contacts":1267,"geoPoint":1271},"University Health Truman Medical Center","64108",[1268,1270],{"name":125,"role":126,"phone":1269},"816-404-4375",{"name":765,"role":131},{"lat":1272,"lon":1273},39.09973,-94.57857,{"facility":1275,"status":8,"city":758,"state":1221,"zip":1276,"country":122,"contacts":1277,"geoPoint":1280},"University of Kansas Cancer Center - Briarcliff","64116",[1278,1279],{"name":125,"role":126,"phone":762},{"name":765,"role":131},{"lat":1272,"lon":1273},{"facility":1282,"status":8,"city":758,"state":1221,"zip":1283,"country":122,"contacts":1284,"geoPoint":1287},"University of Kansas Cancer Center - North","64154",[1285,1286],{"name":125,"role":126,"phone":762,"email":763},{"name":765,"role":131},{"lat":1272,"lon":1273},{"facility":1289,"status":8,"city":1290,"state":1221,"zip":1291,"country":122,"contacts":1292,"geoPoint":1295},"University of Kansas Cancer Center - Lee's Summit","Lee's Summit","64064",[1293,1294],{"name":125,"role":126,"phone":762,"email":763},{"name":765,"role":131},{"lat":1296,"lon":1297},38.91084,-94.38217,{"facility":1299,"status":8,"city":1300,"state":1221,"zip":1301,"country":122,"contacts":1302,"geoPoint":1305},"Sainte Genevieve County Memorial Hospital","Sainte Genevieve","63670",[1303,1304],{"name":125,"role":126,"phone":1259},{"name":262,"role":131},{"lat":1306,"lon":1307},37.98144,-90.04178,{"facility":1309,"status":8,"city":1310,"state":1221,"zip":1311,"country":122,"contacts":1312,"geoPoint":1315},"Washington University School of Medicine","St Louis","63110",[1313,1314],{"name":125,"role":126,"phone":1237,"email":1238},{"name":501,"role":131},{"lat":1316,"lon":1317},38.62727,-90.19789,{"facility":1319,"status":8,"city":1310,"state":1221,"zip":1320,"country":122,"contacts":1321,"geoPoint":1324},"Siteman Cancer Center-South County","63129",[1322,1323],{"name":125,"role":126,"phone":1237,"email":1238},{"name":501,"role":131},{"lat":1316,"lon":1317},{"facility":1326,"status":8,"city":1310,"state":1221,"zip":1327,"country":122,"contacts":1328,"geoPoint":1331},"Missouri Baptist Medical Center","63131",[1329,1330],{"name":125,"role":126,"phone":1259},{"name":262,"role":131},{"lat":1316,"lon":1317},{"facility":1333,"status":8,"city":1310,"state":1221,"zip":1334,"country":122,"contacts":1335,"geoPoint":1338},"Siteman Cancer Center at Christian Hospital","63136",[1336,1337],{"name":125,"role":126,"phone":1237,"email":1238},{"name":501,"role":131},{"lat":1316,"lon":1317},{"facility":1340,"status":8,"city":1341,"state":1221,"zip":1342,"country":122,"contacts":1343,"geoPoint":1346},"Missouri Baptist Sullivan Hospital","Sullivan","63080",[1344,1345],{"name":125,"role":126,"phone":1259},{"name":262,"role":131},{"lat":1347,"lon":1348},38.2081,-91.16042,{"facility":1350,"status":8,"city":1351,"state":1352,"zip":1353,"country":122,"contacts":1354,"geoPoint":1357},"Community Hospital of Anaconda","Anaconda","Montana","59711",[1355,1356],{"name":125,"role":126,"phone":205,"email":206},{"name":208,"role":131},{"lat":1358,"lon":1359},46.12854,-112.94226,{"facility":1361,"status":8,"city":1362,"state":1352,"zip":1363,"country":122,"contacts":1364,"geoPoint":1369},"Billings Clinic Cancer Center","Billings","59101",[1365,1368],{"name":125,"role":126,"phone":1366,"email":1367},"800-996-2663","research@billingsclinic.org",{"name":208,"role":131},{"lat":1370,"lon":1371},45.78329,-108.50069,{"facility":1373,"status":8,"city":1374,"state":1352,"zip":1375,"country":122,"contacts":1376,"geoPoint":1379},"Bozeman Health Deaconess Hospital","Bozeman","59715",[1377,1378],{"name":125,"role":126,"phone":205,"email":206},{"name":208,"role":131},{"lat":1380,"lon":1381},45.67965,-111.03856,{"facility":1383,"status":8,"city":1384,"state":1352,"zip":1385,"country":122,"contacts":1386,"geoPoint":1389},"Benefis Sletten Cancer Institute","Great Falls","59405",[1387,1388],{"name":125,"role":126,"phone":205,"email":206},{"name":208,"role":131},{"lat":1390,"lon":1391},47.50024,-111.30081,{"facility":1393,"status":8,"city":1394,"state":1352,"zip":1395,"country":122,"contacts":1396,"geoPoint":1399},"Logan Health Medical Center","Kalispell","59901",[1397,1398],{"name":125,"role":126,"phone":205,"email":206},{"name":208,"role":131},{"lat":1400,"lon":1401},48.19579,-114.31291,{"facility":1403,"status":8,"city":1404,"state":1352,"zip":1405,"country":122,"contacts":1406,"geoPoint":1409},"Community Medical Center","Missoula","59804",[1407,1408],{"name":125,"role":126,"phone":205,"email":206},{"name":208,"role":131},{"lat":1410,"lon":1411},46.87215,-113.994,{"facility":1413,"status":8,"city":1414,"state":1415,"zip":1416,"country":122,"contacts":1417,"geoPoint":1423},"Jefferson Cherry Hill Hospital","Cherry Hill","New Jersey","08002",[1418,1421],{"name":125,"role":126,"phone":1419,"email":1420},"215-600-9151","ONCTrialNow@jefferson.edu",{"name":1422,"role":131},"Michael Wysota",{"lat":1424,"lon":1425},39.93484,-75.03073,{"facility":1427,"status":8,"city":1428,"state":1415,"zip":1429,"country":122,"contacts":1430,"geoPoint":1433},"Sidney Kimmel Cancer Center Washington Township","Sewell","08080",[1431,1432],{"name":125,"role":126,"phone":1419,"email":1420},{"name":1422,"role":131},{"lat":1434,"lon":1435},39.7665,-75.14434,{"facility":1437,"status":8,"city":1438,"state":1439,"zip":1440,"country":122,"contacts":1441,"geoPoint":1446},"University of Rochester","Rochester","New York","14642",[1442,1444],{"name":125,"role":126,"phone":1443},"585-275-5830",{"name":1445,"role":131},"Paul M. Barr",{"lat":1447,"lon":1448},43.15478,-77.61556,{"facility":1450,"status":8,"city":1451,"state":1439,"zip":1452,"country":122,"contacts":1453,"geoPoint":1457},"Wilmot Cancer Institute at Webster","Webster","14580",[1454,1456],{"name":125,"role":126,"email":1455},"WCICTOresearch@urmc.rochester.edu",{"name":1445,"role":131},{"lat":1458,"lon":1459},43.21229,-77.42999,{"facility":1461,"status":8,"city":1462,"state":1463,"zip":1464,"country":122,"contacts":1465,"geoPoint":1471},"UNC Lineberger Comprehensive Cancer Center","Chapel Hill","North Carolina","27599",[1466,1469],{"name":125,"role":126,"phone":1467,"email":1468},"877-668-0683","cancerclinicaltrials@med.unc.edu",{"name":1470,"role":131},"Christopher E. Jensen",{"lat":1472,"lon":1473},35.9132,-79.05584,{"facility":1475,"status":8,"city":1476,"state":1463,"zip":1477,"country":122,"contacts":1478,"geoPoint":1483},"Duke University Medical Center","Durham","27710",[1479,1481],{"name":125,"role":126,"phone":1480},"888-275-3853",{"name":1482,"role":131},"Danielle M. Brander",{"lat":1484,"lon":1485},35.99403,-78.89862,{"facility":1487,"status":8,"city":1488,"state":1463,"zip":1489,"country":122,"contacts":1490,"geoPoint":1496},"Margaret R Pardee Memorial Hospital","Hendersonville","28791",[1491,1494],{"name":125,"role":126,"phone":1492,"email":1493},"828-696-4716","pardeecancerresearch@unchealth.unc.edu",{"name":1495,"role":131},"John K. Hill",{"lat":1497,"lon":1498},35.31873,-82.46095,{"facility":1500,"status":8,"city":1501,"state":1502,"zip":1503,"country":122,"contacts":1504,"geoPoint":1508},"Sanford Bismarck Medical Center","Bismarck","North Dakota","58501",[1505,1507],{"name":125,"role":126,"phone":1506,"email":1086},"701-323-5760",{"name":1088,"role":131},{"lat":1509,"lon":1510},46.80833,-100.78374,{"facility":1512,"status":8,"city":1513,"state":1502,"zip":1514,"country":122,"contacts":1515,"geoPoint":1518},"Essentia Health Cancer Center-South University Clinic","Fargo","58103",[1516,1517],{"name":125,"role":126,"phone":1098,"email":1099},{"name":1101,"role":131},{"lat":1519,"lon":1520},46.87719,-96.7898,{"facility":1522,"status":8,"city":1513,"state":1502,"zip":1523,"country":122,"contacts":1524,"geoPoint":1527},"Sanford Broadway Medical Center","58122",[1525,1526],{"name":125,"role":126,"phone":1506,"email":1086},{"name":1088,"role":131},{"lat":1519,"lon":1520},{"facility":1529,"status":8,"city":1513,"state":1502,"zip":1523,"country":122,"contacts":1530,"geoPoint":1534},"Sanford Roger Maris Cancer Center",[1531,1533],{"name":125,"role":126,"phone":1532,"email":1086},"701-234-6161",{"name":1088,"role":131},{"lat":1519,"lon":1520},{"facility":1536,"status":8,"city":1537,"state":1538,"zip":1539,"country":122,"contacts":1540,"geoPoint":1546},"OhioHealth O'Bleness Hospital","Athens","Ohio","45701",[1541,1544],{"name":125,"role":126,"phone":1542,"email":1543},"614-788-3860","Jennifer.Sexton@ohiohealth.com",{"name":1545,"role":131},"Basem M. William",{"lat":1547,"lon":1548},39.32924,-82.10126,{"facility":1550,"status":8,"city":1551,"state":1538,"zip":1552,"country":122,"contacts":1553,"geoPoint":1559},"Ohio State University Comprehensive Cancer Center","Columbus","43210",[1554,1557],{"name":125,"role":126,"phone":1555,"email":1556},"800-293-5066","Jamesline@osumc.edu",{"name":1558,"role":131},"Jennifer A. Woyach",{"lat":1560,"lon":1561},39.96118,-82.99879,{"facility":1563,"status":8,"city":1551,"state":1538,"zip":1564,"country":122,"contacts":1565,"geoPoint":1568},"Columbus Oncology and Hematology Associates Inc","43214",[1566,1567],{"name":125,"role":126,"phone":1542,"email":1543},{"name":1545,"role":131},{"lat":1560,"lon":1561},{"facility":1570,"status":8,"city":1551,"state":1538,"zip":1564,"country":122,"contacts":1571,"geoPoint":1574},"Riverside Methodist Hospital",[1572,1573],{"name":125,"role":126,"phone":1542,"email":1543},{"name":1545,"role":131},{"lat":1560,"lon":1561},{"facility":1576,"status":8,"city":1551,"state":1538,"zip":1577,"country":122,"contacts":1578,"geoPoint":1581},"Grant Medical Center","43215",[1579,1580],{"name":125,"role":126,"phone":1542,"email":1543},{"name":1545,"role":131},{"lat":1560,"lon":1561},{"facility":1583,"status":8,"city":1551,"state":1538,"zip":1584,"country":122,"contacts":1585,"geoPoint":1588},"Doctors Hospital","43228",[1586,1587],{"name":125,"role":126,"phone":1542,"email":1543},{"name":1545,"role":131},{"lat":1560,"lon":1561},{"facility":1590,"status":8,"city":1591,"state":1538,"zip":1592,"country":122,"contacts":1593,"geoPoint":1596},"Delaware Health Center-Grady Cancer Center","Delaware","43015",[1594,1595],{"name":125,"role":126,"phone":1542,"email":1543},{"name":1545,"role":131},{"lat":1597,"lon":1598},40.29867,-83.06797,{"facility":1600,"status":8,"city":1591,"state":1538,"zip":1592,"country":122,"contacts":1601,"geoPoint":1604},"Grady Memorial Hospital",[1602,1603],{"name":125,"role":126,"phone":1542,"email":1543},{"name":1545,"role":131},{"lat":1597,"lon":1598},{"facility":1606,"status":8,"city":1607,"state":1538,"zip":1608,"country":122,"contacts":1609,"geoPoint":1612},"Columbus Oncology and Hematology Associates","Dublin","43016",[1610,1611],{"name":125,"role":126,"phone":1542,"email":1543},{"name":1545,"role":131},{"lat":1613,"lon":1614},40.09923,-83.11408,{"facility":1616,"status":8,"city":1607,"state":1538,"zip":1608,"country":122,"contacts":1617,"geoPoint":1620},"Dublin Methodist Hospital",[1618,1619],{"name":125,"role":126,"phone":1542,"email":1543},{"name":1545,"role":131},{"lat":1613,"lon":1614},{"facility":1622,"status":8,"city":1623,"state":1538,"zip":1624,"country":122,"contacts":1625,"geoPoint":1628},"OhioHealth Mansfield Hospital","Mansfield","44903",[1626,1627],{"name":125,"role":126,"phone":1542,"email":1543},{"name":1545,"role":131},{"lat":1629,"lon":1630},40.75839,-82.51545,{"facility":1632,"status":8,"city":1633,"state":1538,"zip":1634,"country":122,"contacts":1635,"geoPoint":1638},"OhioHealth Marion General Hospital","Marion","43302",[1636,1637],{"name":125,"role":126,"phone":1542,"email":1543},{"name":1545,"role":131},{"lat":1639,"lon":1640},40.58867,-83.12852,{"facility":1642,"status":8,"city":1643,"state":1538,"zip":1644,"country":122,"contacts":1645,"geoPoint":1648},"OhioHealth Pickerington Methodist Hospital","Pickerington","43147",[1646,1647],{"name":125,"role":126,"phone":1542,"email":1543},{"name":1545,"role":131},{"lat":1649,"lon":1650},39.88423,-82.7535,{"facility":1652,"status":8,"city":1653,"state":1538,"zip":1654,"country":122,"contacts":1655,"geoPoint":1659},"OhioHealth Westerville Medical Campus\u002FWesterville Cancer Center","Westerville","43082",[1656,1658],{"name":125,"role":126,"phone":1657,"email":1543},"610-788-3860",{"name":1545,"role":131},{"lat":1660,"lon":1661},40.12617,-82.92907,{"facility":1663,"status":8,"city":1664,"state":1665,"zip":1666,"country":122,"contacts":1667,"geoPoint":1673},"University of Oklahoma Health Sciences Center","Oklahoma City","Oklahoma","73104",[1668,1671],{"name":125,"role":126,"phone":1669,"email":1670},"405-271-8777","ou-clinical-trials@ouhsc.edu",{"name":1672,"role":131},"Swaroopa PonnamReddy",{"lat":1674,"lon":1675},35.46756,-97.51643,{"facility":1677,"status":8,"city":1678,"state":1679,"zip":1680,"country":122,"contacts":1681,"geoPoint":1684},"Saint Alphonsus Cancer Care Center-Baker City","Baker City","Oregon","97814",[1682,1683],{"name":125,"role":126,"phone":205,"email":206},{"name":185,"role":131},{"lat":1685,"lon":1686},44.77487,-117.83438,{"facility":1688,"status":8,"city":1689,"state":1679,"zip":1690,"country":122,"contacts":1691,"geoPoint":1697},"Providence Newberg Medical Center","Newberg","97132",[1692,1695],{"name":125,"role":126,"phone":1693,"email":1694},"503-215-2614","CanRsrchStudies@providence.org",{"name":1696,"role":131},"Alison K. Conlin",{"lat":1698,"lon":1699},45.30012,-122.97316,{"facility":1701,"status":8,"city":1702,"state":1679,"zip":1703,"country":122,"contacts":1704,"geoPoint":1707},"Saint Alphonsus Cancer Care Center-Ontario","Ontario","97914",[1705,1706],{"name":125,"role":126,"phone":205,"email":206},{"name":185,"role":131},{"lat":1708,"lon":1709},44.02655,-116.96294,{"facility":1711,"status":8,"city":1712,"state":1679,"zip":1713,"country":122,"contacts":1714,"geoPoint":1717},"Providence Willamette Falls Medical Center","Oregon City","97045",[1715,1716],{"name":125,"role":126,"phone":1693,"email":1694},{"name":1696,"role":131},{"lat":1718,"lon":1719},45.35734,-122.60676,{"facility":1721,"status":8,"city":969,"state":1679,"zip":1722,"country":122,"contacts":1723,"geoPoint":1726},"Providence Portland Medical Center","97213",[1724,1725],{"name":125,"role":126,"phone":1693,"email":1694},{"name":1696,"role":131},{"lat":1727,"lon":1728},45.52345,-122.67621,{"facility":1730,"status":8,"city":969,"state":1679,"zip":1731,"country":122,"contacts":1732,"geoPoint":1735},"Providence Saint Vincent Medical Center","97225",[1733,1734],{"name":125,"role":126,"phone":1693,"email":1694},{"name":1696,"role":131},{"lat":1727,"lon":1728},{"facility":1737,"status":8,"city":1738,"state":1739,"zip":1740,"country":122,"contacts":1741,"geoPoint":1744},"Thomas Jefferson University Hospital","Philadelphia","Pennsylvania","19107",[1742,1743],{"name":125,"role":126,"phone":1419,"email":1420},{"name":1422,"role":131},{"lat":1745,"lon":1746},39.95238,-75.16362,{"facility":1748,"status":8,"city":1738,"state":1739,"zip":1749,"country":122,"contacts":1750,"geoPoint":1753},"Jefferson Torresdale Hospital","19114",[1751,1752],{"name":125,"role":126,"phone":1419,"email":1420},{"name":1422,"role":131},{"lat":1745,"lon":1746},{"facility":1755,"status":8,"city":1756,"state":1757,"zip":1758,"country":122,"contacts":1759,"geoPoint":1765},"Avera Cancer Institute-Aberdeen","Aberdeen","South Dakota","57401",[1760,1763],{"name":125,"role":126,"phone":1761,"email":1762},"605-622-8700","oncregulatory@avera.org",{"name":1764,"role":131},"Shristi Upadhyay Banskota",{"lat":1766,"lon":1767},45.4647,-98.48648,{"facility":1769,"status":8,"city":1770,"state":1757,"zip":1771,"country":122,"contacts":1772,"geoPoint":1777},"Avera Cancer Institute - Mitchell","Mitchell","57301",[1773,1776],{"name":125,"role":126,"phone":1774,"email":1775},"605-322-3096","OncRegulatory@avera.org",{"name":1764,"role":131},{"lat":1778,"lon":1779},43.70943,-98.0298,{"facility":1781,"status":8,"city":1782,"state":1757,"zip":1783,"country":122,"contacts":1784,"geoPoint":1788},"Avera Cancer Institute at Pierre","Pierre","57501",[1785,1787],{"name":125,"role":126,"phone":1786,"email":1775},"605-322-3095",{"name":1764,"role":131},{"lat":1789,"lon":1790},44.36832,-100.35097,{"facility":1792,"status":8,"city":1793,"state":1757,"zip":1794,"country":122,"contacts":1795,"geoPoint":1800},"Sanford Cancer Center Oncology Clinic","Sioux Falls","57104",[1796,1799],{"name":125,"role":126,"phone":1797,"email":1798},"605-312-3320","OncologyClinicTrialsSF@sanfordhealth.org",{"name":1088,"role":131},{"lat":1801,"lon":1802},43.54369,-96.72796,{"facility":1804,"status":8,"city":1793,"state":1757,"zip":1805,"country":122,"contacts":1806,"geoPoint":1809},"Avera Cancer Institute","57105",[1807,1808],{"name":125,"role":126,"phone":1786,"email":1775},{"name":1764,"role":131},{"lat":1801,"lon":1802},{"facility":1811,"status":8,"city":1793,"state":1757,"zip":1812,"country":122,"contacts":1813,"geoPoint":1817},"Sanford USD Medical Center - Sioux Falls","57117-5134",[1814,1816],{"name":125,"role":126,"phone":1797,"email":1815},"OncologyClinicalTrialsSF@SanfordHealth.org",{"name":1088,"role":131},{"lat":1801,"lon":1802},{"facility":1819,"status":8,"city":1820,"state":1757,"zip":1821,"country":122,"contacts":1822,"geoPoint":1826},"Avera Cancer Institute at Yankton","Yankton","57078",[1823,1825],{"name":125,"role":126,"phone":1824,"email":1775},"605-655-1800",{"name":1764,"role":131},{"lat":1827,"lon":1828},42.87111,-97.39728,{"facility":1830,"status":8,"city":1831,"state":1832,"zip":1833,"country":122,"contacts":1834,"geoPoint":1837},"Baptist Memorial Hospital and Cancer Center-Collierville","Collierville","Tennessee","38017",[1835,1836],{"name":125,"role":126,"phone":1211,"email":1212},{"name":1214,"role":131},{"lat":1838,"lon":1839},35.04204,-89.66453,{"facility":1841,"status":8,"city":1842,"state":1832,"zip":1843,"country":122,"contacts":1844,"geoPoint":1847},"Baptist Memorial Hospital and Cancer Center-Memphis","Memphis","38120",[1845,1846],{"name":125,"role":126,"phone":1211,"email":1212},{"name":1214,"role":131},{"lat":1848,"lon":1849},35.14953,-90.04898,{"facility":1851,"status":8,"city":1852,"state":544,"zip":1853,"country":122,"contacts":1854,"geoPoint":1859},"Swedish Cancer Institute-Edmonds","Edmonds","98026",[1855,1858],{"name":125,"role":126,"phone":1856,"email":1857},"206-215-2343","PCRC-NCORP@Swedish.org",{"name":1696,"role":131},{"lat":1860,"lon":1861},47.81065,-122.37736,{"facility":1863,"status":1864,"city":1865,"state":544,"zip":1866,"country":122,"geoPoint":1867},"Swedish Cancer Institute-Issaquah","SUSPENDED","Issaquah","98029",{"lat":1868,"lon":1869},47.5301,-122.03262,{"facility":1871,"status":8,"city":1872,"state":544,"zip":1873,"country":122,"contacts":1874,"geoPoint":1877},"Swedish Medical Center-First Hill","Seattle","98122",[1875,1876],{"name":125,"role":126,"phone":1856,"email":1857},{"name":1696,"role":131},{"lat":1878,"lon":1879},47.60621,-122.33207,{"facility":1881,"status":8,"city":1882,"state":1883,"zip":1884,"country":122,"contacts":1885,"geoPoint":1888},"Duluth Clinic Ashland","Ashland","Wisconsin","54806",[1886,1887],{"name":125,"role":126,"phone":1098,"email":1099},{"name":1101,"role":131},{"lat":1889,"lon":1890},46.59244,-90.8838,{"facility":1892,"status":8,"city":1893,"state":1883,"zip":1894,"country":122,"contacts":1895,"geoPoint":1901},"Saint Vincent Hospital Cancer Center Green Bay","Green Bay","54301",[1896,1899],{"name":125,"role":126,"phone":1897,"email":1898},"920-433-8889","WI_research_admin@hshs.org",{"name":1900,"role":131},"Anthony J. Jaslowski",{"lat":1902,"lon":1903},44.51916,-88.01983,{"facility":1905,"status":8,"city":1893,"state":1883,"zip":1906,"country":122,"contacts":1907,"geoPoint":1911},"Saint Vincent Hospital Cancer Center at Saint Mary's","54303",[1908,1910],{"name":125,"role":126,"phone":1897,"email":1909},"wi_research_admin@hshs.org",{"name":1900,"role":131},{"lat":1902,"lon":1903},{"facility":1913,"status":8,"city":1914,"state":1883,"zip":1915,"country":122,"contacts":1916,"geoPoint":1922},"Gundersen Lutheran Medical Center","La Crosse","54601",[1917,1920],{"name":125,"role":126,"phone":1918,"email":1919},"608-775-2385","cancerctr@gundersenhealth.org",{"name":1921,"role":131},"Michael O. Ojelabi",{"lat":1923,"lon":1924},43.80136,-91.23958,{"facility":1926,"status":8,"city":1927,"state":1883,"zip":1928,"country":122,"contacts":1929,"geoPoint":1935},"William S Middleton VA Medical Center","Madison","53705",[1930,1933],{"name":125,"role":126,"phone":1931,"phoneExt":1932},"608-256-1901","17007",{"name":1934,"role":131},"Christopher D. Fletcher",{"lat":1936,"lon":1937},43.07305,-89.40123,{"facility":1939,"status":8,"city":1940,"state":1883,"zip":1941,"country":122,"contacts":1942,"geoPoint":1947},"ProHealth D N Greenwald Center","Mukwonago","53149",[1943,1945],{"name":125,"role":126,"email":1944},"research.institute@phci.org",{"name":1946,"role":131},"Timothy R. Wassenaar",{"lat":1948,"lon":1949},42.86668,-88.33343,{"facility":1951,"status":8,"city":1952,"state":1883,"zip":1953,"country":122,"contacts":1954,"geoPoint":1958},"ProHealth Oconomowoc Memorial Hospital","Oconomowoc","53066",[1955,1957],{"name":125,"role":126,"phone":1956},"262-928-7878",{"name":1946,"role":131},{"lat":1959,"lon":1960},43.11167,-88.49927,{"facility":1962,"status":8,"city":1963,"state":1883,"zip":1964,"country":122,"contacts":1965,"geoPoint":1968},"Saint Vincent Hospital Cancer Center at Oconto Falls","Oconto Falls","54154",[1966,1967],{"name":125,"role":126,"phone":1897,"email":1898},{"name":1900,"role":131},{"lat":1969,"lon":1970},44.87388,-88.14288,{"facility":1972,"status":8,"city":1973,"state":1883,"zip":1974,"country":122,"contacts":1975,"geoPoint":1978},"Saint Vincent Hospital Cancer Center at Sturgeon Bay","Sturgeon Bay","54235-1495",[1976,1977],{"name":125,"role":126,"phone":1897,"email":1909},{"name":1900,"role":131},{"lat":1979,"lon":1980},44.83416,-87.37704,{"facility":1982,"status":8,"city":1983,"state":1883,"zip":1984,"country":122,"contacts":1985,"geoPoint":1990},"UW Cancer Center at ProHealth Care","Waukesha","53188",[1986,1989],{"name":125,"role":126,"phone":1987,"email":1988},"262-928-5539","Chanda.miller@phci.org",{"name":1946,"role":131},{"lat":1991,"lon":1992},43.01168,-88.23148,[1994],{"name":1995,"role":126,"phone":1996,"email":1997},"Jayke Giese","773-702-9171","leukemiaprotocols@alliancenctn.org",[1999],{"name":2000,"affiliation":13,"role":2001},"Jennifer R Brown, MD","STUDY_CHAIR",[],[],{"nct_id":4,"conditions":2005,"biomarkers":2007},[19,2006],"Lymphoid Leukemia",[2008,2009,2010,2011,2012],"BCL2 Gene","BTK Gene","CD19 Gene","CD5 Gene","MS4A1 Gene",{"nct_id":4,"found":2014,"summary":2015,"prompt_version":2025},true,{"design":2016,"status":2017,"heading":2018,"summary":2019,"follow_up":2020,"word_count":2021,"commitments":2022,"compensation":2023,"drugs_mentioned":2024},"This is a phase III interventional study planning to enroll 466 participants. It compares two treatment approaches: zanubrutinib alone versus zanubrutinib with sonrotoclax.","completed","Testing Sonrotoclax with Zanubrutinib for Untreated CLL\u002FSLL","This study is looking at whether adding the anti-cancer drug sonrotoclax to the standard treatment zanubrutinib works better than zanubrutinib alone for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who haven't been treated before. Sonrotoclax works by blocking a protein called Bcl-2, which helps cancer cells survive. Zanubrutinib blocks another protein called BTK, which can help stop cancer cells from growing and spreading. The study aims to see if this combination can prevent the cancer from getting worse for a longer time. You might be able to join if you are 65 or older, and have untreated CLL\u002FSLL. The study is currently unclear on its recruitment status.","Participants will be followed from their initial randomization date until the cancer progresses or they pass away, for up to 10 years.",111,"Participants will receive either zanubrutinib or a combination of zanubrutinib and sonrotoclax by mouth. They will also undergo CT scans, bone marrow aspirations, and blood sample collections.","Not stated in the trial record.",[32,38],"v2"]