[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07352995":3,"trial-entities:NCT07352995":75,"trial-summary:NCT07352995":80},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":22,"study_type":23,"primary_purpose":24,"phases":25,"enrollment_info":27,"interventions":30,"primary_outcomes":38,"secondary_outcomes":42,"sex":43,"minimum_age":44,"maximum_age":17,"healthy_volunteers":15,"eligibility_criteria":45,"std_ages":56,"locations":59,"central_contacts":68,"overall_officials":69,"references":73,"see_also_links":74},"NCT07352995","2025P000709","Thermal Measurements of the Gut With a Colonoscope Compatible Thermal Probe","Colonoscopic Investigation of the Correlation Between Bowel Wall Inflammation and Luminal Temperature Rise in IBD","ENROLLING_BY_INVITATION","2029-12","2026-04","2026-04-20","2026-03-25","Massachusetts General Hospital","OTHER",false,"The goal of this clinical trial is to use a modified thermal probe to measure temperature rise in the colonic mucosa of participants with inflammatory bowel disease, Crohn's disease, and\u002For ulcerative colitis. The main question it aims to answer is:\n\nIs the thermal probe an effective device to use to detect temperature rise in the colonic mucosa?\n\nDuring the participant's standard of care colonoscopy, the thermal probe will be inserted into the colonoscope. The thermal probe is connected to a temperature transmitter that collects and saves the temperature of the colon in real time.",null,[19,20,21],"Inflammatory Bowel Diseases","Crohn Disease","Ulcerative Colitis",[],"INTERVENTIONAL","DEVICE_FEASIBILITY",[26],"NA",{"count":28,"type":29},20,"ESTIMATED",[31],{"type":32,"name":33,"description":34,"armGroupLabels":35},"DEVICE","Feasibility of using a thermal probe to measure temperature rise in colonic mucosa","10 participants in each arm will be enrolled in this study. All consented participants will receive the same intervention.",[36,37],"IBD, Crohn's Disease, and\u002For UC","Undergoing Colorectal Screening",[39],{"measure":40,"timeFrame":41},"Ability of thermal probe to collect temperature measurements from colonic mucosa","Thermal measurements are collected during the study procedure and analyzed within one year of collection.",[],"ALL","18 Years",{"inclusion":46,"exclusion":52,"raw_text":55},[47,48,49,50,51],"Participants 18 years or older","Participants undergoing elective colonoscopy","Participants capable of following requirements","Participants capable of providing informed consent","Participants with a diagnosis of IBD, Crohn's disease, and\u002For ulcerative colitis or participants undergoing colorectal cancer screening",[53,54],"Participants contraindicated for colonoscopy, including experiencing acute events within the last 6 weeks prior to the colonoscopy (i.e. subjects suffering from a myocardial infarction (heart attack), diagnosis of peritonitis (the inflammation of the membrane lining of the abdominal wall), diagnosis of hemodynamic instability (shock), surgery involving colonic anastomosis (reconnection of the colon), and\u002For bowel injury (from trauma or surgery)","Participants who are pregnant","Inclusion Criteria:\n\n* Participants 18 years or older\n* Participants undergoing elective colonoscopy\n* Participants capable of following requirements\n* Participants capable of providing informed consent\n* Participants with a diagnosis of IBD, Crohn's disease, and\u002For ulcerative colitis or participants undergoing colorectal cancer screening\n\nExclusion Criteria:\n\n* Participants contraindicated for colonoscopy, including experiencing acute events within the last 6 weeks prior to the colonoscopy (i.e. subjects suffering from a myocardial infarction (heart attack), diagnosis of peritonitis (the inflammation of the membrane lining of the abdominal wall), diagnosis of hemodynamic instability (shock), surgery involving colonic anastomosis (reconnection of the colon), and\u002For bowel injury (from trauma or surgery)\n* Participants who are pregnant",[57,58],"ADULT","OLDER_ADULT",[60],{"facility":13,"city":61,"state":62,"zip":63,"country":64,"geoPoint":65},"Boston","Massachusetts","02114","United States",{"lat":66,"lon":67},42.35843,-71.05977,[],[70],{"name":71,"affiliation":13,"role":72},"Guillermo Tearney, M.D., PhD","PRINCIPAL_INVESTIGATOR",[],[],{"nct_id":4,"conditions":76,"biomarkers":79},[77,20,78,21],"Colorectal Carcinoma","Inflammatory Bowel Disease",[],{"nct_id":4,"found":15,"summary":17,"prompt_version":17}]