[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07365436":3,"trial-entities:NCT07365436":74,"trial-summary:NCT07365436":78},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":21,"study_type":22,"primary_purpose":14,"phases":23,"enrollment_info":25,"interventions":28,"primary_outcomes":35,"secondary_outcomes":39,"sex":40,"minimum_age":41,"maximum_age":42,"healthy_volunteers":15,"eligibility_criteria":43,"std_ages":55,"locations":58,"central_contacts":67,"overall_officials":68,"references":72,"see_also_links":73},"NCT07365436","2025P001541","Imaging the Colon Using a Colonoscope Compatible Imaging Probe","Study for Imaging the Lower Gastrointestinal Tract Using a Colonoscopy-Compatible OCT Probe","ENROLLING_BY_INVITATION","2029-12","2026-07","2026-07-13","2026-03-03","Massachusetts General Hospital","OTHER",false,"The goal of this study is to use a colonoscope compatible device capable of taking images of the lower gastrointestinal tract. The main question it aims to answer is:\n\nIs the colonoscope compatible optical coherence tomography probe (CC-OCT probe) an effective device to use to take images of the gut?\n\nDuring the participant's standard of care colonoscopy, the CC-OCT probe will be inserted into the colonoscope. The CC-OCT probe will then collect images of the participant's gastrointestinal tract in real time.",null,[19,20],"Colon Polyps","Colonoscopy",[],"INTERVENTIONAL",[24],"NA",{"count":26,"type":27},250,"ESTIMATED",[29],{"type":30,"name":31,"description":32,"armGroupLabels":33},"DEVICE","Feasibility of using a CC-OCT probe to image the GI tract","250 participants will be enrolled in this study. All consented participants will receive the same intervention.",[34],"Undergoing Colorectal Screening",[36],{"measure":37,"timeFrame":38},"Ability of the CC-OCT to image the lower GI tract","Images are collected during the study procedure and analyzed within one year of collection",[],"ALL","45 Years","75 Years",{"inclusion":44,"exclusion":48,"raw_text":54},[45,46,47],"45 years of age or older","Capable of giving informed consent","Capable of following bowel prep instructions",[49,50,51,52,53],"75 years of age or older","Any contraindication to bowel prep or colonoscopy","Current diagnosis of any bleeding disorders","Currently using drugs that interfere with coagulation (excluding low-dose aspirin)","Pregnancy","Inclusion Criteria:\n\n* 45 years of age or older\n* Capable of giving informed consent\n* Capable of following bowel prep instructions\n\nExclusion Criteria:\n\n* 75 years of age or older\n* Any contraindication to bowel prep or colonoscopy\n* Current diagnosis of any bleeding disorders\n* Currently using drugs that interfere with coagulation (excluding low-dose aspirin)\n* Pregnancy",[56,57],"ADULT","OLDER_ADULT",[59],{"facility":13,"city":60,"state":61,"zip":62,"country":63,"geoPoint":64},"Boston","Massachusetts","02114","United States",{"lat":65,"lon":66},42.35843,-71.05977,[],[69],{"name":70,"affiliation":13,"role":71},"Guillermo Tearney, M.D., PhD","PRINCIPAL_INVESTIGATOR",[],[],{"nct_id":4,"conditions":75,"biomarkers":77},[76],"Colon Polyp",[],{"nct_id":4,"found":79,"summary":80,"prompt_version":89},true,{"design":81,"status":82,"heading":6,"summary":83,"follow_up":84,"word_count":85,"commitments":86,"compensation":87,"drugs_mentioned":88},"This is an interventional study with 250 participants. All participants will receive the same intervention.","completed","This study is testing a new device called a colonoscope compatible optical coherence tomography probe (CC-OCT probe). This probe is designed to take detailed images of your lower gastrointestinal (GI) tract during a standard colonoscopy. The main goal is to see if the CC-OCT probe is an effective tool for imaging the gut. You might be able to join if you are 45 years or older, can give informed consent, and can follow bowel preparation instructions. The study aims to enroll 250 participants, and success will be measured by the ability of the CC-OCT to capture images of the lower GI tract, which will be analyzed within one year.","Images are collected during the study procedure and analyzed within one year of collection.",109,"During your standard colonoscopy, the CC-OCT probe will be inserted into the colonoscope to collect images of your gastrointestinal tract in real time.","Not stated in the trial record.",[],"v2"]