[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07390084":3,"trial-entities:NCT07390084":90,"trial-summary:NCT07390084":94},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":16,"conditions":17,"keywords":20,"study_type":23,"primary_purpose":24,"phases":25,"enrollment_info":27,"interventions":30,"primary_outcomes":43,"secondary_outcomes":48,"sex":49,"minimum_age":50,"maximum_age":51,"healthy_volunteers":52,"eligibility_criteria":53,"std_ages":64,"locations":66,"central_contacts":81,"overall_officials":85,"references":88,"see_also_links":89},"NCT07390084","STUDY00023737","Exploring the Decision to Drink (More) Alcohol Following Manipulations of Stress and Social Context","RECRUITING","2027-06-30","2026-07","2026-07-24","2026-02-01","University of Washington","OTHER",false,"This preregistration documents an experiment examining the effects of acute stress and social context on alcohol-related decision-making. The study uses a 2x2 factorial design (stress vs. control × social vs. alone) with dyadic recruitment.","Behavioral data:\n\nOur first set of hypotheses tests whether the decision is influenced by stress and social context:\n\nH1a: Stress affects the decision between alcoholic and non-alcoholic drinks, so that participants in the stress conditions choose alcoholic over non-alcoholic drinks more often compared to participants in the no stress conditions.\n\nH1b: Social context affects the decision between alcoholic and non-alcoholic drinks, so that participants in the social conditions choose alcoholic over non-alcoholic drinks more often compared to participants in the alone conditions.\n\nH1c: We test two competing predictions:\n\n(I) The effect of stress on the decision between alcohol and non-alcoholic drinks is modulated by social context, so that the effect of stress is stronger for participants that are in the social condition.\n\n(II) The effect of stress on the decision between alcohol and non-alcoholic drinks is modulated by social context, so that the effect of stress is weaker for participants that are in the social condition\n\nDrift diffusion modeling:\n\nOur second set of hypotheses test how the decision might be influenced by stress and social context:\n\nH2a: Stress affects the bias (but not the drift rate or boundary) parameter of the drift diffusion model, so that the bias parameter is more positive for participants in the stress conditions.\n\nH2b: Social context affects the bias (but not the drift rate or boundary) parameter of the drift diffusion model, so that the bias parameter is more positive for participants in the social conditions.\n\nH2c: Stress and social context have an interactive effect on the bias (but not the drift rate or boundary) parameter of the drift diffusion model, so that the bias parameter is either more or less positive for stressed participants who are in the social condition (in line with H1c).",[18,19],"Psychological Stress","Social Interaction",[21,22],"stress induction","value-based decision-making","INTERVENTIONAL","BASIC_SCIENCE",[26],"NA",{"count":28,"type":29},160,"ESTIMATED",[31,38],{"type":13,"name":32,"description":33,"armGroupLabels":34},"Stress","Participants randomly assigned to the stress condition will undergo the standard protocol of the Trier Social Stress Test. Participants randomly assigned to the control condition will undergo a validated, non-stressful control procedure mirroring the TSST.",[35,36,37],"Control Alone","Stress Alone","Stress Social",{"type":13,"name":39,"description":40,"armGroupLabels":41},"Social Context","Participants randomly assigned to the social condition will make decisions about consuming alcohol with a known peer. Participants randomly assigned to the control condition will make decisions about consuming alcohol alone.",[35,42,37],"Control Social",[44],{"measure":45,"description":46,"timeFrame":47},"Proportion of choices for alcoholic over non-alcoholic drinks.","Each participant will complete a two alternative forced-choice task in which they make repeated decisions between alcoholic and non-alcoholic drinks.","5 minutes",[],"ALL","21 Years","50 Years",true,{"inclusion":54,"exclusion":57,"raw_text":63},[55,56],"Drinking alcohol at least once a week","Consuming 4 (female) or 5 (male) drinks in one occasion at least once a month",[58,59,60,61,62],"Currently pregnant or trying to become pregnant","Past or current treatment for alcohol use","Past or current medical condition that contraindicates alcohol use","Past or current reaction to alcohol that contraindicates alcohol use","Past or current medication that contraindicates alcohol use","Inclusion Criteria:\n\n* Drinking alcohol at least once a week\n* Consuming 4 (female) or 5 (male) drinks in one occasion at least once a month\n\nExclusion Criteria:\n\n* Currently pregnant or trying to become pregnant\n* Past or current treatment for alcohol use\n* Past or current medical condition that contraindicates alcohol use\n* Past or current reaction to alcohol that contraindicates alcohol use\n* Past or current medication that contraindicates alcohol use",[65],"ADULT",[67],{"facility":12,"status":7,"city":68,"state":69,"zip":70,"country":71,"contacts":72,"geoPoint":78},"Seattle","Washington","98195","United States",[73],{"name":74,"role":75,"phone":76,"email":77},"Jonas Dora, PhD","CONTACT","206-741-6330","jdora@uw.edu",{"lat":79,"lon":80},47.60621,-122.33207,[82],{"name":83,"role":75,"phone":84,"email":77},"Jonas Dora","2067416330",[86],{"name":83,"affiliation":12,"role":87},"PRINCIPAL_INVESTIGATOR",[],[],{"nct_id":4,"conditions":91,"biomarkers":93},[92],"Alcohol Consumption",[],{"nct_id":4,"found":52,"summary":95,"prompt_version":105},{"design":96,"status":97,"heading":98,"summary":99,"follow_up":100,"word_count":101,"commitments":102,"compensation":103,"drugs_mentioned":104},"This is an interventional study planning to enroll 160 participants. It uses a 2x2 design, meaning participants will be randomly assigned to different combinations of stress and social situations.","completed","Exploring Stress, Social Context, and Alcohol Choices","This study is looking at how stress and being around other people might influence your decisions about drinking alcohol. Researchers want to see if stress or social situations make people choose alcoholic drinks more often. You might be asked to do a stress test or a non-stressful activity, and then make choices about drinking either alone or with a peer. The study is looking for 160 participants between 21 and 50 years old who drink alcohol at least once a week and have at least 4-5 drinks on one occasion monthly. People who are pregnant, have a history of alcohol use treatment, or medical conditions that make alcohol unsafe cannot participate. The study's current status is unclear.","The primary outcome, choices for alcoholic over non-alcoholic drinks, is measured at 5 minutes.",117,"Participants will undergo either a stress test (Trier Social Stress Test) or a non-stressful control procedure. They will then make decisions about consuming alcohol, either alone or with a known peer.","Not stated in the trial record.",[32],"v2"]