[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07400653":3,"trial-entities:NCT07400653":1350,"trial-summary:NCT07400653":1354},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":24,"study_type":36,"primary_purpose":37,"phases":38,"enrollment_info":40,"interventions":43,"primary_outcomes":58,"secondary_outcomes":62,"sex":131,"minimum_age":132,"maximum_age":17,"healthy_volunteers":133,"eligibility_criteria":134,"std_ages":156,"locations":159,"central_contacts":1340,"overall_officials":1341,"references":1345,"see_also_links":1346},"NCT07400653","C6491008","A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D)","EVALUATING THE EFFICACY AND SAFETY OF MET097, A FULLY-BIASED ULTRA LONG-ACTING GLP-1RA, IN PEOPLE WITH OVERWEIGHT OR OBESITY AND TYPE 2 DIABETES: A PHASE 3, MULTI-CENTER RANDOMIZED PLACEBO-CONTROLLED TRIAL (VESPER-5)","ACTIVE_NOT_RECRUITING","2028-05-16","2026-07","2026-07-27","2026-02-24","Pfizer","INDUSTRY",true,"The purpose of this clinical study is to learn about the safety and effects of the study medicine to help adults with obesity or overweight and type 2 diabetes lose weight. Being overweight or obese means carrying too much body weight. Type 2 diabetes is a condition where there is too much sugar in the blood.\n\nThe study medicine is given by a shot under the skin in the belly area. The participants will be trained to do this at home once every week.\n\nAbout 660 out of 1000 adults will also receive the study medicine and about 330 out of 1000 adults will receive placebo. A placebo does not have any medicine in it but looks just like the medicine being studied. The investigators will compare the experiences of people receiving the study medicine to those of the people who do not. This will help us assess if the study medicine is safe and effective.\n\nPeople will take part in this study for about 21 months. During this time, they will have about 14 study visits at the site and 5 over the phone.",null,[19,20,21,22,23],"Obesity","Overweight and\u002For Obesity","Overweight","Diabetes, Type 2","Type 2 Diabetes",[25,26,27,28,29,30,31,32,33,34,21,19,35],"Overnutrition","Nutrition Disorders","Nutritional and Metabolic Diseases","Body Weight","Signs and Symptoms","Pathological Conditions, Signs and Symptoms","Diabetes Mellitus","Glucose Metabolism Disorders","Metabolic Diseases","Endocrine System Diseases","Diabetes Mellitus, Type 2","INTERVENTIONAL","TREATMENT",[39],"PHASE3",{"count":41,"type":42},1044,"ACTUAL",[44,54],{"type":45,"name":46,"description":47,"armGroupLabels":48,"otherNames":52},"DRUG","PF-08653944","By Subcutaneous Injection",[49,50,51],"Treatment Arm 1","Treatment Arm 2","Treatment Arm 3",[53],"MET097",{"type":55,"name":56,"description":47,"armGroupLabels":57},"OTHER","Placebo",[56],[59],{"measure":60,"timeFrame":61},"Percent Change from baseline in body weight","Baseline, Week 64",[63,66,68,70,72,74,76,78,80,82,84,87,89,92,94,96,98,100,102,104,106,108,110,112,114,116,118,121,123,125,127,129],{"measure":64,"timeFrame":65},"Change from baseline in body weight","Baseline, Week 64 and 84",{"measure":67,"timeFrame":65},"Change in HbA1c (%) from baseline",{"measure":69,"timeFrame":65},"Percentage of Participants achieving ≥5% of body weight reduction from baseline",{"measure":71,"timeFrame":65},"Percentage of Participants achieving ≥10% of body weight reduction from baseline",{"measure":73,"timeFrame":65},"Percentage of Participants achieving ≥15% of body weight reduction from baseline",{"measure":75,"timeFrame":65},"Percentage of Participants achieving ≥20% of body weight reduction from baseline",{"measure":77,"timeFrame":65},"Change from baseline in Fasting triglycerides",{"measure":79,"timeFrame":65},"Change from baseline in Non-high-density lipoprotein cholesterol (non-HDL-C)",{"measure":81,"timeFrame":65},"Change from baseline in Systolic Blood Pressure (SBP)",{"measure":83,"timeFrame":65},"Change from baseline in Short Form 36 health survey (SF-36) physical function domain score",{"measure":85,"timeFrame":86},"Percent change from baseline in body weight","Baseline, Week 84",{"measure":88,"timeFrame":65},"Change from baseline in waist circumference",{"measure":90,"timeFrame":91},"Percentage of Participants Achieving HbA1c \u003C7%","Week 64 and Week 84",{"measure":93,"timeFrame":91},"Percentage of Participants Achieving HbA1c ≤6.5%",{"measure":95,"timeFrame":91},"Percentage of Participants Achieving HbA1c \u003C5.7%",{"measure":97,"timeFrame":65},"Change from Baseline in Fasting Glucose",{"measure":99,"timeFrame":65},"Change from Baseline in Fasting insulin",{"measure":101,"timeFrame":65},"Change from baseline in Total Cholesterol",{"measure":103,"timeFrame":65},"Change from baseline in Low-density lipoprotein cholesterol",{"measure":105,"timeFrame":65},"Change from baseline in Very low-density lipoprotein cholesterol",{"measure":107,"timeFrame":65},"Change from baseline in High-density lipoprotein cholesterol",{"measure":109,"timeFrame":65},"Change from Baseline in Diastolic Blood Pressure (DBP)",{"measure":111,"timeFrame":65},"Percent change from baseline in high-sensitivity C-reactive protein",{"measure":113,"timeFrame":65},"Change from Baseline in EuroQoL 5-Dimension 5-Level (EQ5D-5L)",{"measure":115,"timeFrame":65},"Change from Baseline in Control of Eating Questionnaire (CoEQ)",{"measure":117,"timeFrame":65},"Change from Baseline in Food Noise Questionnaire (FNQ)",{"measure":119,"timeFrame":120},"Number of Participants With Treatment Emergent Adverse Events (TEAEs)","Week 84",{"measure":122,"timeFrame":120},"Number of Participants with Serious adverse events (SAEs)",{"measure":124,"timeFrame":120},"Number of Participants with Adverse Events of Clinical Interest (AECIs)",{"measure":126,"timeFrame":120},"Number of Participants With Clinical Laboratory Abnormalities",{"measure":128,"timeFrame":120},"Number of participants with anti-drug antibodies (ADAs)",{"measure":130,"timeFrame":120},"Pharmacokinetics (PK): Maximum Observed Plasma Concentration (Cmax) of PF-08653944","ALL","18 Years",false,{"inclusion":135,"exclusion":146,"raw_text":155},[136,137,138,139,140,141,142,143,144,145],"Provision of signed and dated informed consent form (ICF)","Male or female adults, aged ≥18 years","Have a BMI at Screening of ≥27.0 kg\u002Fm2","Have T2DM for at least 6 months before Screening based on participant reported history or documentation of the disease diagnostic criteria","Have HbA1c value between ≥6.5% (48 mmol\u002Fmol) and ≤10.0% (86.0 mmol\u002Fmol) at Screening with stable therapy for at least 90 days prior to Screening\u002FVisit 1. T2DM may be treated with:","Diet and exercise alone or in combination with: Any oral antidiabetic therapy per local labeling EXCEPT DPP-4 inhibitors. Participant may NOT be on GLP-1 agonists or insulin","Participants must be motivated and willing to:","Self-inject study medication (or be aided by caregiver if needed),","Perform finger-stick glucose monitoring as required.","Have a history of at least 1 self-reported unsuccessful dietary effort to lose body weight.",[147,148,149,150,151,152,153,154],"Female who is breastfeeding, or who is pregnant","Unwilling or unable to follow contraceptive requirements","Diagnosis of Type 1 diabetes, or any other types of diabetes except T2DM.","Severe hypoglycemia and\u002For hypoglycemia unawareness within the 6 months prior to Screening","Poorly controlled hypertension","Have a prior or planned surgical treatment for obesity (excluding liposuction or abdominoplasty if performed \\>1 year prior to screening)","Have taken within 3 months prior to randomization, medications (prescribed or over-the counter) intended to promote weight loss","Are receiving or have received within 3 months prior to screening chronic (\\>2 weeks or 14 days) systemic glucocorticoid therapy","Inclusion Criteria:\n\n* Provision of signed and dated informed consent form (ICF)\n* Male or female adults, aged ≥18 years\n* Have a BMI at Screening of ≥27.0 kg\u002Fm2\n* Have T2DM for at least 6 months before Screening based on participant reported history or documentation of the disease diagnostic criteria\n* Have HbA1c value between ≥6.5% (48 mmol\u002Fmol) and ≤10.0% (86.0 mmol\u002Fmol) at Screening with stable therapy for at least 90 days prior to Screening\u002FVisit 1. T2DM may be treated with:\n\n  --Diet and exercise alone or in combination with: Any oral antidiabetic therapy per local labeling EXCEPT DPP-4 inhibitors. Participant may NOT be on GLP-1 agonists or insulin\n* Participants must be motivated and willing to:\n\n  * Self-inject study medication (or be aided by caregiver if needed),\n  * Perform finger-stick glucose monitoring as required.\n* Have a history of at least 1 self-reported unsuccessful dietary effort to lose body weight.\n\nExclusion Criteria:\n\n* Female who is breastfeeding, or who is pregnant\n* Unwilling or unable to follow contraceptive requirements\n* Diagnosis of Type 1 diabetes, or any other types of diabetes except T2DM.\n* Severe hypoglycemia and\u002For hypoglycemia unawareness within the 6 months prior to Screening\n* Poorly controlled hypertension\n* Have a prior or planned surgical treatment for obesity (excluding liposuction or abdominoplasty if performed \\>1 year prior to screening)\n* Have taken within 3 months prior to randomization, medications (prescribed or over-the counter) intended to promote weight loss\n* Are receiving or have received within 3 months prior to screening chronic (\\>2 weeks or 14 days) systemic glucocorticoid therapy",[157,158],"ADULT","OLDER_ADULT",[160,169,176,183,190,197,204,211,218,226,229,236,244,247,254,261,264,271,278,285,292,299,306,314,321,327,335,342,350,357,365,373,380,387,394,401,409,416,424,431,439,446,453,460,467,475,482,485,493,501,505,508,515,519,523,530,537,544,552,559,566,573,580,587,591,598,602,609,616,619,626,633,642,649,656,664,669,676,683,690,697,704,708,712,721,729,736,740,744,748,755,762,769,772,779,783,787,791,798,805,812,819,826,835,842,849,853,860,867,874,878,885,889,896,900,904,908,915,922,929,936,939,946,950,957,964,971,975,979,986,994,1001,1008,1012,1016,1020,1027,1034,1041,1048,1055,1063,1067,1071,1078,1082,1089,1096,1103,1111,1118,1125,1132,1139,1146,1153,1157,1164,1173,1181,1188,1195,1199,1203,1210,1217,1224,1228,1235,1242,1249,1256,1263,1270,1277,1284,1291,1298,1305,1312,1319,1326,1333],{"facility":161,"city":162,"state":163,"zip":164,"country":165,"geoPoint":166},"CenExel Anaheim Clinical Trials","Anaheim","California","92801","United States",{"lat":167,"lon":168},33.83529,-117.9145,{"facility":170,"city":171,"state":163,"zip":172,"country":165,"geoPoint":173},"Alliance Research Institute","Canoga Park","91304",{"lat":174,"lon":175},34.20112,-118.59814,{"facility":177,"city":178,"state":163,"zip":179,"country":165,"geoPoint":180},"Core Healthcare Group","Cerritos","90703",{"lat":181,"lon":182},33.85835,-118.06479,{"facility":184,"city":185,"state":163,"zip":186,"country":165,"geoPoint":187},"CenExel CNS - Collaborative Neuroscience Research","Los Alamitos","90720",{"lat":188,"lon":189},33.80307,-118.07256,{"facility":191,"city":192,"state":163,"zip":193,"country":165,"geoPoint":194},"Catalina Research Institute, LLC","Montclair","91763",{"lat":195,"lon":196},34.07751,-117.68978,{"facility":198,"city":199,"state":163,"zip":200,"country":165,"geoPoint":201},"Cure Clinical Research","Orange","92866",{"lat":202,"lon":203},33.78779,-117.85311,{"facility":205,"city":206,"state":163,"zip":207,"country":165,"geoPoint":208},"CenExel CIT","Riverside","92506",{"lat":209,"lon":210},33.95335,-117.39616,{"facility":212,"city":213,"state":163,"zip":214,"country":165,"geoPoint":215},"Lundquist Institute for Biomedical Innovation at Harbor- UCLA Medical Center","Torrance","90502",{"lat":216,"lon":217},33.83585,-118.34063,{"facility":219,"city":220,"state":221,"zip":222,"country":165,"geoPoint":223},"CenExcel Rocky Mountain Clinical Research, LLC","Englewood","Colorado","80113",{"lat":224,"lon":225},39.64777,-104.98776,{"facility":227,"city":220,"state":221,"zip":222,"country":165,"geoPoint":228},"CenExel Denver CO (Rocky Mountain Clinical Research)",{"lat":224,"lon":225},{"facility":230,"city":231,"state":221,"zip":232,"country":165,"geoPoint":233},"Neuro-Sight Vision Care","Lakewood","80226",{"lat":234,"lon":235},39.70471,-105.08137,{"facility":237,"city":238,"state":239,"zip":240,"country":165,"geoPoint":241},"AMR Clinical","Fort Myers","Florida","33912",{"lat":242,"lon":243},26.62168,-81.84059,{"facility":245,"city":238,"state":239,"zip":240,"country":165,"geoPoint":246},"Pedro P. Ylisastigui, MD",{"lat":242,"lon":243},{"facility":248,"city":249,"state":239,"zip":250,"country":165,"geoPoint":251},"Private Practice Adjacent to For Eyes Optical","Hialeah","33014",{"lat":252,"lon":253},25.8576,-80.27811,{"facility":255,"city":256,"state":239,"zip":257,"country":165,"geoPoint":258},"Miami Eye Institute","Hollywood","33024",{"lat":259,"lon":260},26.0112,-80.14949,{"facility":262,"city":256,"state":239,"zip":257,"country":165,"geoPoint":263},"Research Centers of America",{"lat":259,"lon":260},{"facility":265,"city":266,"state":239,"zip":267,"country":165,"geoPoint":268},"Future Medical Research (Civia Health)","Longwood","32750",{"lat":269,"lon":270},28.70305,-81.3384,{"facility":272,"city":273,"state":239,"zip":274,"country":165,"geoPoint":275},"Advanced Clinical Research","Miami","33156",{"lat":276,"lon":277},25.77427,-80.19366,{"facility":279,"city":280,"state":239,"zip":281,"country":165,"geoPoint":282},"Indago Research & Health Center, Inc","Miami Lakes","33016",{"lat":283,"lon":284},25.90871,-80.30866,{"facility":286,"city":287,"state":239,"zip":288,"country":165,"geoPoint":289},"Optimal Research Sites, LLC","Orange City","32763",{"lat":290,"lon":291},28.94888,-81.29867,{"facility":293,"city":294,"state":239,"zip":295,"country":165,"geoPoint":296},"Oviedo Medical Research","Oviedo","32765",{"lat":297,"lon":298},28.67,-81.20812,{"facility":300,"city":301,"state":239,"zip":302,"country":165,"geoPoint":303},"CenExel FCR - ForCare Clinical Research","Tampa","33613",{"lat":304,"lon":305},27.94752,-82.45843,{"facility":307,"city":308,"state":309,"zip":310,"country":165,"geoPoint":311},"DelRicht Research","Atlanta","Georgia","30329",{"lat":312,"lon":313},33.749,-84.38798,{"facility":315,"city":316,"state":309,"zip":317,"country":165,"geoPoint":318},"CenExel iResearch, LLC","Decatur","30030",{"lat":319,"lon":320},33.77483,-84.29631,{"facility":315,"city":322,"state":309,"zip":323,"country":165,"geoPoint":324},"Savannah","31405",{"lat":325,"lon":326},32.08354,-81.09983,{"facility":328,"city":329,"state":330,"zip":331,"country":165,"geoPoint":332},"Patient First Clinical Trials (PFCTRIALS)","Lutherville","Maryland","21093",{"lat":333,"lon":334},39.42122,-76.62608,{"facility":307,"city":336,"state":337,"zip":338,"country":165,"geoPoint":339},"Springfield","Missouri","65807",{"lat":340,"lon":341},37.21533,-93.29824,{"facility":343,"city":344,"state":345,"zip":346,"country":165,"geoPoint":347},"Quality Clinical Research Inc","Omaha","Nebraska","68114",{"lat":348,"lon":349},41.25626,-95.94043,{"facility":351,"city":352,"state":345,"zip":353,"country":165,"geoPoint":354},"Primary clinical Research","Papillion","68046",{"lat":355,"lon":356},41.15444,-96.04224,{"facility":358,"city":359,"state":360,"zip":361,"country":165,"geoPoint":362},"Hassman Research Institute","Marlton","New Jersey","08053",{"lat":363,"lon":364},39.89122,-74.92183,{"facility":366,"city":367,"state":368,"zip":369,"country":165,"geoPoint":370},"Forum Health_Cary (Civia)","Cary","North Carolina","27511",{"lat":371,"lon":372},35.79154,-78.78112,{"facility":374,"city":375,"state":368,"zip":376,"country":165,"geoPoint":377},"Eximia EquiHealth Research","Durham","27704",{"lat":378,"lon":379},35.99403,-78.89862,{"facility":381,"city":382,"state":368,"zip":383,"country":165,"geoPoint":384},"Sahana Optometry PLLC dba Family Eye Wellness","Holly Springs","27540",{"lat":385,"lon":386},35.65127,-78.83362,{"facility":388,"city":389,"state":368,"zip":390,"country":165,"geoPoint":391},"Burke Primary Care","Morganton","28655",{"lat":392,"lon":393},35.74541,-81.68482,{"facility":395,"city":396,"state":368,"zip":397,"country":165,"geoPoint":398},"Eximia Research - NC, LLC","Raleigh","27607",{"lat":399,"lon":400},35.7721,-78.63861,{"facility":402,"city":403,"state":404,"zip":405,"country":165,"geoPoint":406},"Tribe Clinical Research LLC.- Greenville","Greenville","South Carolina","29607",{"lat":407,"lon":408},34.85262,-82.39401,{"facility":410,"city":411,"state":404,"zip":412,"country":165,"geoPoint":413},"Tribe Clinical Research LLC. - Spartanburg","Spartanburg","29301",{"lat":414,"lon":415},34.94957,-81.93205,{"facility":417,"city":418,"state":419,"zip":420,"country":165,"geoPoint":421},"Civia Health Goodlettsville","Goodlettsville","Tennessee","37072",{"lat":422,"lon":423},36.32311,-86.71333,{"facility":425,"city":426,"state":419,"zip":427,"country":165,"geoPoint":428},"Civia Health Nashville","La Vergne","37086",{"lat":429,"lon":430},36.01562,-86.58194,{"facility":432,"city":433,"state":434,"zip":435,"country":165,"geoPoint":436},"Amarillo Medical Specialists LLP","Amarillo","Texas","79124",{"lat":437,"lon":438},35.222,-101.8313,{"facility":440,"city":441,"state":434,"zip":442,"country":165,"geoPoint":443},"Forum Austin (Civia Health)","Austin","78578",{"lat":444,"lon":445},30.26715,-97.74306,{"facility":447,"city":448,"state":434,"zip":449,"country":165,"geoPoint":450},"GLRI El Paso Research","El Paso","79936",{"lat":451,"lon":452},31.75872,-106.48693,{"facility":454,"city":455,"state":434,"zip":456,"country":165,"geoPoint":457},"Cardiovascular Specialists of Willowbrook","Houston","77070",{"lat":458,"lon":459},29.76328,-95.36327,{"facility":461,"city":462,"state":434,"zip":463,"country":165,"geoPoint":464},"Dallas Clinical Research Center (Pillar Clinical Research)","Richardson","75080",{"lat":465,"lon":466},32.94818,-96.72972,{"facility":468,"city":469,"state":470,"zip":471,"country":165,"geoPoint":472},"Pantheon Clinical Research","Bountiful","Utah","84010",{"lat":473,"lon":474},40.88939,-111.88077,{"facility":476,"city":477,"state":470,"zip":478,"country":165,"geoPoint":479},"CenExel Salt Lake City UT (JBR Clinical Research)","Salt Lake City","84107",{"lat":480,"lon":481},40.76078,-111.89105,{"facility":483,"city":477,"state":470,"zip":478,"country":165,"geoPoint":484},"Murray Vision Center PC",{"lat":480,"lon":481},{"facility":486,"city":487,"state":488,"zip":489,"country":165,"geoPoint":490},"ERA Health Research","Redmond","Washington","98052",{"lat":491,"lon":492},47.67399,-122.12151,{"facility":494,"city":495,"zip":496,"country":497,"geoPoint":498},"Centro de Investigaciones Metabólicas (CINME)","Buenos Aires","C1056ABI","Argentina",{"lat":499,"lon":500},-34.61315,-58.37723,{"facility":502,"city":495,"zip":503,"country":497,"geoPoint":504},"CEDIC","C1060",{"lat":499,"lon":500},{"facility":506,"city":495,"country":497,"geoPoint":507},"Centro Medico Viamonte",{"lat":499,"lon":500},{"facility":509,"city":510,"zip":511,"country":497,"geoPoint":512},"Clinica Privada Velez Sarsfield","Córdoba","5000",{"lat":513,"lon":514},-31.40648,-64.18853,{"facility":516,"city":510,"zip":517,"country":497,"geoPoint":518},"Instituto de Investigaciones Clinicas Cordoba","X5000AAW",{"lat":513,"lon":514},{"facility":520,"city":510,"zip":521,"country":497,"geoPoint":522},"CIDIM","X5000AVE",{"lat":513,"lon":514},{"facility":524,"city":525,"zip":526,"country":497,"geoPoint":527},"CIPADI - Centro Integral de Prevencion Y Atencion en Diabetes","Godoy Cruz","M5501ARP",{"lat":528,"lon":529},-32.92533,-68.84428,{"facility":531,"city":532,"zip":533,"country":497,"geoPoint":534},"Centro de Investigaciones Médicas Tucuman","San Miguel de Tucumán","T4000AXL",{"lat":535,"lon":536},-26.81601,-65.21051,{"facility":538,"city":539,"zip":540,"country":497,"geoPoint":541},"Instituto Medico Catamarca (IMEC)","Santa Fe","S2000",{"lat":542,"lon":543},-31.64881,-60.70868,{"facility":545,"city":546,"zip":547,"country":548,"geoPoint":549},"MHAT Botevgrad","Botevgrad","2140","Bulgaria",{"lat":550,"lon":551},42.90799,23.79274,{"facility":553,"city":554,"zip":555,"country":548,"geoPoint":556},"Medical Center 4Life EOOD","Burgas","8018",{"lat":557,"lon":558},42.50651,27.46886,{"facility":560,"city":561,"zip":562,"country":548,"geoPoint":563},"Multiprofile Hospital for Active Treatment Dobrich AD (MHAT Dobrich AD)","Dobrich","9300",{"lat":564,"lon":565},43.56491,27.83138,{"facility":567,"city":568,"zip":569,"country":548,"geoPoint":570},"Medical Center New Polyclinic Gabrovo Ltd.","Gabrovo","5300",{"lat":571,"lon":572},42.87419,25.31823,{"facility":574,"city":575,"zip":576,"country":548,"geoPoint":577},"Medical Center Zdrave 1","Kozloduy","3320",{"lat":578,"lon":579},43.77691,23.73001,{"facility":581,"city":582,"zip":583,"country":548,"geoPoint":584},"FutureMeds Plovdiv","Plovdiv","4000",{"lat":585,"lon":586},42.15387,24.75001,{"facility":588,"city":582,"zip":589,"country":548,"geoPoint":590},"MHAT Sveta Karidad EAD","4004",{"lat":585,"lon":586},{"facility":592,"city":593,"zip":594,"country":548,"geoPoint":595},"Diagnostic Consultative Center Aleksandrovska","Sofia","1431",{"lat":596,"lon":597},42.69751,23.32415,{"facility":599,"city":593,"zip":600,"country":548,"geoPoint":601},"Medical Center Hera EOOD","1710",{"lat":596,"lon":597},{"facility":603,"city":604,"zip":605,"country":548,"geoPoint":606},"Prevencia - 2000 - Medical Center for Prehospital Medical Care OOD","Stara Zagora","6000",{"lat":607,"lon":608},42.43205,25.64262,{"facility":610,"city":611,"zip":612,"country":548,"geoPoint":613},"Medical Center - Clinic Nova EOOD","Varna","9020",{"lat":614,"lon":615},43.21912,27.91024,{"facility":617,"city":611,"zip":612,"country":548,"geoPoint":618},"Medical Centre Pratia Clinic EOOD",{"lat":614,"lon":615},{"facility":620,"city":621,"zip":622,"country":548,"geoPoint":623},"MC Nevromedics Ltd.","Veliko Tarnovo","5005",{"lat":624,"lon":625},43.08124,25.62904,{"facility":627,"city":628,"zip":629,"country":548,"geoPoint":630},"Medical Center Berbatov","Yambol","8600",{"lat":631,"lon":632},42.48243,26.50006,{"facility":634,"city":635,"state":636,"zip":637,"country":638,"geoPoint":639},"Centricity Research Etobicoke Endocrinology","Etobicoke","Ontario","M9R 4E1","Canada",{"lat":640,"lon":641},43.64415,-79.56985,{"facility":643,"city":644,"state":636,"zip":645,"country":638,"geoPoint":646},"The Wharton Medical Clinic Clinical Trials Inc","Hamilton","L8L 5G8",{"lat":647,"lon":648},43.25011,-79.84963,{"facility":650,"city":651,"state":636,"zip":652,"country":638,"geoPoint":653},"LMC Diabetes & Endocrinology - Bayview (Centricity Research Toronto LMC Multispecialty)","Toronto","M4G 3E8",{"lat":654,"lon":655},43.70643,-79.39864,{"facility":657,"city":658,"state":659,"zip":660,"country":638,"geoPoint":661},"Centricity Research Mirabel Multispecialty (Centricity Research)","Mirabel","Quebec","J7J 2K8",{"lat":662,"lon":663},45.65008,-74.08251,{"facility":665,"city":666,"zip":667,"country":668},"Diacentrum Brandys n.L.","Brandys Nad Lebem","25001","Czechia",{"facility":670,"city":671,"zip":672,"country":668,"geoPoint":673},"Nemocnice Jihlava","Jihlava","58601",{"lat":674,"lon":675},49.3961,15.59124,{"facility":677,"city":678,"zip":679,"country":668,"geoPoint":680},"Edumed s.r.o.","Náchod","54701",{"lat":681,"lon":682},50.4167,16.16289,{"facility":684,"city":685,"zip":686,"country":668,"geoPoint":687},"CCR Ostrava","Ostrava","702 00",{"lat":688,"lon":689},49.83465,18.28204,{"facility":691,"city":692,"zip":693,"country":668,"geoPoint":694},"Pratia Pardubice","Pardubice","53002",{"lat":695,"lon":696},50.04075,15.77659,{"facility":698,"city":699,"zip":700,"country":668,"geoPoint":701},"Fakultní nemocnice Královské Vinohrady","Prague","100 34",{"lat":702,"lon":703},50.08804,14.42076,{"facility":705,"city":699,"zip":706,"country":668,"geoPoint":707},"Synexus\u002FTrialmed Prague","120 00",{"lat":702,"lon":703},{"facility":709,"city":699,"zip":710,"country":668,"geoPoint":711},"ResTrial s.r.o.","18100",{"lat":702,"lon":703},{"facility":713,"city":714,"state":715,"zip":716,"country":717,"geoPoint":718},"CDG Studienambulanz Hartard","Munich","Bavaria","80809","Germany",{"lat":719,"lon":720},48.13743,11.57549,{"facility":722,"city":723,"state":724,"zip":725,"country":717,"geoPoint":726},"Studienzentrum FMZ Radowsky","Leipzig","Saxony","04179",{"lat":727,"lon":728},51.33962,12.37129,{"facility":730,"city":731,"zip":732,"country":717,"geoPoint":733},"Klinische Forschung Berlin-Mitte GmbH","Berlin","10117",{"lat":734,"lon":735},52.52437,13.41053,{"facility":737,"city":731,"zip":738,"country":717,"geoPoint":739},"FutureMeds Berlin","10629",{"lat":734,"lon":735},{"facility":741,"city":731,"zip":742,"country":717,"geoPoint":743},"Velocity Clinical Research Germany","10787",{"lat":734,"lon":735},{"facility":745,"city":731,"zip":746,"country":717,"geoPoint":747},"Diabetespraxis Dr. Braun","13187",{"lat":734,"lon":735},{"facility":749,"city":750,"zip":751,"country":717,"geoPoint":752},"Practice Dr. Kirsch and Colleague, Zentrum fur klinische Forschung","Cologne","51069",{"lat":753,"lon":754},50.93333,6.95,{"facility":756,"city":757,"zip":758,"country":717,"geoPoint":759},"Klinische Forschung Dresden GmbH \u002F Pratia","Dresden","01069",{"lat":760,"lon":761},51.05089,13.73832,{"facility":763,"city":764,"zip":765,"country":717,"geoPoint":766},"Medizentrum Essen Borbeck","Essen","45355",{"lat":767,"lon":768},51.45657,7.01228,{"facility":770,"city":764,"zip":765,"country":717,"geoPoint":771},"Praxis am Markt - Dr. Bernd Becker",{"lat":767,"lon":768},{"facility":773,"city":774,"zip":775,"country":717,"geoPoint":776},"Klinische Forschung Hamburg GmbH \u002F Pratia","Hamburg","20253",{"lat":777,"lon":778},53.55073,9.99302,{"facility":780,"city":774,"zip":781,"country":717,"geoPoint":782},"Diabetes Studienzentrum Wilhelmsburg","21109",{"lat":777,"lon":778},{"facility":784,"city":774,"zip":785,"country":717,"geoPoint":786},"Diabeteszentrum Hamburg-West","22607",{"lat":777,"lon":778},{"facility":788,"city":789,"zip":790,"country":717},"Praxis Reinfeld Mitte","Holstein","23858",{"facility":792,"city":793,"zip":794,"country":717,"geoPoint":795},"Klinische Forschung Karlsruhe GmbH","Karlsruhe","76137",{"lat":796,"lon":797},49.00937,8.40444,{"facility":799,"city":800,"zip":801,"country":717,"geoPoint":802},"Gemeinschaftspraxis Dres. H.Kittner und K.Hartig","Naunhof","04683",{"lat":803,"lon":804},51.2777,12.58827,{"facility":806,"city":807,"zip":808,"country":717,"geoPoint":809},"FutureMeds Frankfurt\u002FOffenbach","Offenbach","63065",{"lat":810,"lon":811},50.10061,8.76647,{"facility":813,"city":814,"zip":815,"country":717,"geoPoint":816},"Zentrum für klinische Forschung Allgäu-Oberschwaben","Wangen","88239",{"lat":817,"lon":818},47.6895,9.83247,{"facility":820,"city":821,"zip":822,"country":717,"geoPoint":823},"Medislim GmbH","Weinheim","69469",{"lat":824,"lon":825},49.54887,8.66697,{"facility":827,"city":828,"state":829,"zip":830,"country":831,"geoPoint":832},"Santa Familia PTG Lodz","Lodz","WOJ Lodzkie","90-302","Poland",{"lat":833,"lon":834},51.77058,19.47395,{"facility":836,"city":837,"zip":838,"country":831,"geoPoint":839},"Zdrowie Osteo Medic sc L i A Racewicz, A i J Supronik","Bialystok","15-351",{"lat":840,"lon":841},53.13333,23.16433,{"facility":843,"city":844,"zip":845,"country":831,"geoPoint":846},"NZOZ Centrum Medyczne KERmed","Bydgoszcz","85-231",{"lat":847,"lon":848},53.1235,18.00762,{"facility":850,"city":844,"zip":851,"country":831,"geoPoint":852},"Centrum medyczne Pratia Bydgoszcz","85-796",{"lat":847,"lon":848},{"facility":854,"city":855,"zip":856,"country":831,"geoPoint":857},"Pratia Chojnice","Chojnice","89-600",{"lat":858,"lon":859},53.69554,17.55701,{"facility":861,"city":862,"zip":863,"country":831,"geoPoint":864},"Synexus Polska Sp. z o.o., Oddzial w Czestochowie","Częstochowa","42-202",{"lat":865,"lon":866},50.79646,19.12409,{"facility":868,"city":869,"zip":870,"country":831,"geoPoint":871},"Synexus Polska Sp z o.o.","Gdansk","80-382",{"lat":872,"lon":873},54.35227,18.64912,{"facility":875,"city":869,"zip":876,"country":831,"geoPoint":877},"Centrum Badan Klinicznych PI-House Sp. z o.o.","80-546",{"lat":872,"lon":873},{"facility":879,"city":880,"zip":881,"country":831,"geoPoint":882},"Centrum Medyczne Pratia Gdynia","Gdynia","81-338",{"lat":883,"lon":884},54.51889,18.53188,{"facility":886,"city":880,"zip":887,"country":831,"geoPoint":888},"Synexus Polska Sp. z o.o. Oddzial w Gdyni","81-537",{"lat":883,"lon":884},{"facility":890,"city":891,"zip":892,"country":831,"geoPoint":893},"Synexus Polska Sp. Z O.O. Oddzial W Katowicach","Katowice","40-040",{"lat":894,"lon":895},50.2597,19.02173,{"facility":897,"city":891,"zip":898,"country":831,"geoPoint":899},"Centrum Medyczne Pratia Katowice","40-081",{"lat":894,"lon":895},{"facility":901,"city":828,"zip":902,"country":831,"geoPoint":903},"Synexus Polska Sp. z o.o., Oddzial w Lodzi","90-127",{"lat":833,"lon":834},{"facility":905,"city":828,"zip":906,"country":831,"geoPoint":907},"Centrum Terapii Współczesnej J.M. Jasnorzewska Spółka Komandytowo-Akcyjna","90-338",{"lat":833,"lon":834},{"facility":909,"city":910,"zip":911,"country":831,"geoPoint":912},"Ekamed Sp. z o. o.","Lublin","20-718",{"lat":913,"lon":914},51.25058,22.57009,{"facility":916,"city":917,"zip":918,"country":831,"geoPoint":919},"FutureMeds Olsztyn","Olsztyn","10-165",{"lat":920,"lon":921},53.78376,20.49272,{"facility":923,"city":924,"zip":925,"country":831,"geoPoint":926},"Medicome Sp. z o.o. Oświęcimskie Centrum Badań Klinicznych","Oświęcim","32-600",{"lat":927,"lon":928},50.03437,19.21037,{"facility":930,"city":931,"zip":932,"country":831,"geoPoint":933},"IRMED","Piotrkow Trybunalski","97-300",{"lat":934,"lon":935},51.40547,19.70321,{"facility":937,"city":931,"zip":932,"country":831,"geoPoint":938},"Trialmed CRS",{"lat":934,"lon":935},{"facility":940,"city":941,"zip":942,"country":831,"geoPoint":943},"Synexus Polska Sp. z o.o., Oddział w Poznaniu","Poznan","60-702",{"lat":944,"lon":945},52.40692,16.92993,{"facility":947,"city":941,"zip":948,"country":831,"geoPoint":949},"Praktyka Lekarska Ewa Krzyzagorska","61-655",{"lat":944,"lon":945},{"facility":951,"city":952,"zip":953,"country":831,"geoPoint":954},"ETG Siedlce","Siedlce","08-110",{"lat":955,"lon":956},52.16772,22.29006,{"facility":958,"city":959,"zip":960,"country":831,"geoPoint":961},"Metabolica Sp. z o.o., NZOZ METABOLICA Ośrodek Badań Klinicznych","Tarnów","33-100",{"lat":962,"lon":963},50.01381,20.98698,{"facility":965,"city":966,"zip":967,"country":831,"geoPoint":968},"Instytut Diabetologii.sp.z.o.o.","Warsaw","02-117",{"lat":969,"lon":970},52.22977,21.01178,{"facility":972,"city":966,"zip":973,"country":831,"geoPoint":974},"Synexus Polska Sp. z o.o., Oddzial w Warszawie","02-672",{"lat":969,"lon":970},{"facility":976,"city":966,"zip":977,"country":831,"geoPoint":978},"Etg Warszawa","02-677",{"lat":969,"lon":970},{"facility":980,"city":981,"zip":982,"country":831,"geoPoint":983},"Synexus Polska Sp. z o.o., Oddział we Wrocławiu","Wroclaw","50-381",{"lat":984,"lon":985},51.10286,17.03006,{"facility":987,"city":988,"zip":989,"country":990,"geoPoint":991},"Minimed S.R.L.","Bacau","600274","Romania",{"lat":992,"lon":993},46.56718,26.91384,{"facility":995,"city":996,"zip":997,"country":990,"geoPoint":998},"Futuremeds S.R.L., Brasov","Brasov","500388",{"lat":999,"lon":1000},45.64861,25.60613,{"facility":1002,"city":1003,"zip":1004,"country":990,"geoPoint":1005},"Hightech Medical Services S.R.L (Centrul pentru Studiul Metabolismului)","Bucharest","011053",{"lat":1006,"lon":1007},44.43225,26.10626,{"facility":1009,"city":1003,"zip":1010,"country":990,"geoPoint":1011},"Institutul National de Endocrinologie \"C.I. Parhon\"","011863",{"lat":1006,"lon":1007},{"facility":1013,"city":1003,"zip":1014,"country":990,"geoPoint":1015},"Institutul Clinic Fundeni","022328",{"lat":1006,"lon":1007},{"facility":1017,"city":1003,"zip":1018,"country":990,"geoPoint":1019},"Fundatia Dr Victor Babes","30303",{"lat":1006,"lon":1007},{"facility":1021,"city":1022,"zip":1023,"country":990,"geoPoint":1024},"Futuremeds S.R.L., Craiova","Craiova","200115",{"lat":1025,"lon":1026},44.31667,23.8,{"facility":1028,"city":1029,"zip":1030,"country":990,"geoPoint":1031},"Futuremeds S.R.L., Galati","Galati","800183",{"lat":1032,"lon":1033},45.43687,28.05028,{"facility":1035,"city":1036,"zip":1037,"country":990,"geoPoint":1038},"Centru Medical \"GRANDMED\"","Oradea","410032",{"lat":1039,"lon":1040},47.0458,21.91833,{"facility":1042,"city":1043,"zip":1044,"country":990,"geoPoint":1045},"Sc Gensan Srl\u002FPoliclinica Astra","Sibiu","550371",{"lat":1046,"lon":1047},45.8,24.15,{"facility":1049,"city":1050,"zip":1051,"country":990,"geoPoint":1052},"Centrul Medical Mediab - Mediab Srl","Târgu Mureş","540142",{"lat":1053,"lon":1054},46.54245,24.55747,{"facility":1056,"city":1057,"zip":1058,"country":1059,"geoPoint":1060},"DIABEDA s.r.o.","Bratislava","831 06","Slovakia",{"lat":1061,"lon":1062},48.14816,17.10674,{"facility":1064,"city":1057,"zip":1065,"country":1059,"geoPoint":1066},"Medispektrum s.r.o.","85101",{"lat":1061,"lon":1062},{"facility":1068,"city":1069,"zip":1070,"country":1059},"Poliklinika Váš Lekár","Bratislava - Ružinov","91109",{"facility":1072,"city":1073,"zip":1074,"country":1059,"geoPoint":1075},"Cardio D&R Košice","Košice","040 22",{"lat":1076,"lon":1077},48.71441,21.25802,{"facility":1079,"city":1073,"zip":1080,"country":1059,"geoPoint":1081},"Medical group Kosice s.r.o.","04001",{"lat":1076,"lon":1077},{"facility":1083,"city":1084,"zip":1085,"country":1059,"geoPoint":1086},"Tatratrial s.r.o.","Rožňava","048 01",{"lat":1087,"lon":1088},48.66009,20.53758,{"facility":1090,"city":1091,"zip":1092,"country":1059,"geoPoint":1093},"JAL s.r.o.","Trnava","91701",{"lat":1094,"lon":1095},48.37773,17.58603,{"facility":1097,"city":1098,"zip":1099,"country":1059,"geoPoint":1100},"Medivasa s.r.o","Žilina","010 01",{"lat":1101,"lon":1102},49.22315,18.73941,{"facility":1104,"city":1105,"state":1105,"zip":1106,"country":1107,"geoPoint":1108},"Hospital Universitario Virgen de la Victoria","Málaga","29010","Spain",{"lat":1109,"lon":1110},36.72016,-4.42034,{"facility":1112,"city":1113,"zip":1114,"country":1107,"geoPoint":1115},"Hospital Universitari Vall d'Hebron","Barcelona","08035",{"lat":1116,"lon":1117},41.38879,2.15899,{"facility":1119,"city":1120,"zip":1121,"country":1107,"geoPoint":1122},"Hospital Vithas Sevilla","Castilleja de la Cuesta","41950",{"lat":1123,"lon":1124},37.38594,-6.05258,{"facility":1126,"city":1127,"zip":1128,"country":1107,"geoPoint":1129},"Futuremeds Spain Cadiz","Chiclana de la Frontera","11139",{"lat":1130,"lon":1131},36.41976,-6.14367,{"facility":1133,"city":1134,"zip":1135,"country":1107,"geoPoint":1136},"Futuremeds Spain Madrid","Madrid","28003",{"lat":1137,"lon":1138},40.4165,-3.70256,{"facility":1140,"city":1141,"zip":1142,"country":1107,"geoPoint":1143},"Hospital Virgen del Camino","Sanlúcar de Barrameda","11540",{"lat":1144,"lon":1145},36.77808,-6.3515,{"facility":1147,"city":1148,"zip":1149,"country":1107,"geoPoint":1150},"Nuevas Tecnologías en Diabetes y Endocrinología S.L.","Seville","41003",{"lat":1151,"lon":1152},37.38283,-5.97317,{"facility":1154,"city":1148,"zip":1155,"country":1107,"geoPoint":1156},"Futuremeds Spain Sevilla","41012",{"lat":1151,"lon":1152},{"facility":1158,"city":1159,"zip":1160,"country":1107,"geoPoint":1161},"Ecg Médica S.L.","Valencia","46015",{"lat":1162,"lon":1163},39.47391,-0.37966,{"facility":1165,"city":1166,"state":1167,"zip":1168,"country":1169,"geoPoint":1170},"Civia Health Sunderland","Hendon","CITY of Sunderland","SR1 1PB","United Kingdom",{"lat":1171,"lon":1172},51.6,-0.21667,{"facility":1174,"city":1175,"state":1176,"zip":1177,"country":1169,"geoPoint":1178},"FutureMeds Glasgow McCafferty House","Glasgow","Scotland","G20 7BE",{"lat":1179,"lon":1180},55.86515,-4.25763,{"facility":1182,"city":1183,"zip":1184,"country":1169,"geoPoint":1185},"Synexus Glasgow Clinical Research Centre","Bellshill","ML4 3NJ",{"lat":1186,"lon":1187},55.81667,-4.01667,{"facility":1189,"city":1190,"zip":1191,"country":1169,"geoPoint":1192},"Synexus Midlands Clinical Research Centre","Birmingham","B15 2SQ",{"lat":1193,"lon":1194},52.48142,-1.89983,{"facility":1196,"city":1190,"zip":1197,"country":1169,"geoPoint":1198},"FutureMeds Birmingham","B21 9RY",{"lat":1193,"lon":1194},{"facility":1200,"city":1190,"zip":1201,"country":1169,"geoPoint":1202},"Civia Health_Boots Birmingham","B4 7TA",{"lat":1193,"lon":1194},{"facility":1204,"city":1205,"zip":1206,"country":1169,"geoPoint":1207},"Southmead Hospital","Bristol","BS10 5NB",{"lat":1208,"lon":1209},51.45523,-2.59665,{"facility":1211,"city":1212,"zip":1213,"country":1169,"geoPoint":1214},"FutureMeds Liverpool","Bromborough","CH62 6EE",{"lat":1215,"lon":1216},53.3485,-2.97935,{"facility":1218,"city":1219,"zip":1220,"country":1169,"geoPoint":1221},"Panthera Biopartners Limited - Enfield","Enfield","EN3 4GS",{"lat":1222,"lon":1223},51.65147,-0.08497,{"facility":1225,"city":1175,"zip":1226,"country":1169,"geoPoint":1227},"Panthera Biopartners Limited - Glasgow","G51 4RY",{"lat":1179,"lon":1180},{"facility":1229,"city":1230,"zip":1231,"country":1169,"geoPoint":1232},"Bodyline Medical Clinic, Crosby Civia Health","Liverpool","L22 4QQ",{"lat":1233,"lon":1234},53.41058,-2.97794,{"facility":1236,"city":1237,"zip":1238,"country":1169,"geoPoint":1239},"FutureMeds London","London","NW10 2PB",{"lat":1240,"lon":1241},51.50853,-0.12574,{"facility":1243,"city":1244,"zip":1245,"country":1169,"geoPoint":1246},"Synexus Manchester Clinical Research Centre","Manchester","M15 6SE",{"lat":1247,"lon":1248},53.48095,-2.23743,{"facility":1250,"city":1251,"zip":1252,"country":1169,"geoPoint":1253},"Kiltearn Medical Centre","Nantwich","CW5 5NX",{"lat":1254,"lon":1255},53.06878,-2.52051,{"facility":1257,"city":1258,"zip":1259,"country":1169,"geoPoint":1260},"FutureMeds Newcastle","Newcastle upon Tyne","NE6 1SG",{"lat":1261,"lon":1262},54.97328,-1.61396,{"facility":1264,"city":1265,"zip":1266,"country":1169,"geoPoint":1267},"Danes Camp Medical Centre","Northampton","NN4 0NY",{"lat":1268,"lon":1269},52.25,-0.88333,{"facility":1271,"city":1272,"zip":1273,"country":1169,"geoPoint":1274},"Civia Health_Boots Nottingham","Nottingham","NG1 3QS,",{"lat":1275,"lon":1276},52.9536,-1.15047,{"facility":1278,"city":1279,"zip":1280,"country":1169,"geoPoint":1281},"Bodyline Medical Clinic Warrington Civia Health","Paddington","WA1 3TZ",{"lat":1282,"lon":1283},51.51558,-0.1763,{"facility":1285,"city":1286,"zip":1287,"country":1169,"geoPoint":1288},"Panthera Biopartners Limited - Preston","Preston","PR2 9QB",{"lat":1289,"lon":1290},53.76282,-2.70452,{"facility":1292,"city":1293,"zip":1294,"country":1169,"geoPoint":1295},"Panthera Biopartners Limited - Rochdale","Rochdale","OL11 4AU",{"lat":1296,"lon":1297},53.61766,-2.1552,{"facility":1299,"city":1300,"zip":1301,"country":1169,"geoPoint":1302},"Clifton Medical Centre","Rotherham","S651DA",{"lat":1303,"lon":1304},53.43012,-1.35678,{"facility":1306,"city":1307,"zip":1308,"country":1169,"geoPoint":1309},"Ashfields Primary Care Centre","Sandbach","CW11 1EQ",{"lat":1310,"lon":1311},53.14515,-2.36251,{"facility":1313,"city":1314,"zip":1315,"country":1169,"geoPoint":1316},"Panthera Biopartners Limited - Sheffield","Sheffield","S2 5FX",{"lat":1317,"lon":1318},53.38297,-1.4659,{"facility":1320,"city":1321,"zip":1322,"country":1169,"geoPoint":1323},"Bodyline Medical Clinic, St Helens Civia Health","St Helens","WA9 1AF",{"lat":1324,"lon":1325},53.45,-2.73333,{"facility":1327,"city":1328,"zip":1329,"country":1169,"geoPoint":1330},"FutureMeds Teesside","Stockton-on-Tees","TS19 8PE",{"lat":1331,"lon":1332},54.56848,-1.3187,{"facility":1334,"city":1335,"zip":1336,"country":1169,"geoPoint":1337},"Panthera Biopartners Limited - York","York","YO24 4LJ",{"lat":1338,"lon":1339},53.95763,-1.08271,[],[1342],{"name":1343,"affiliation":13,"role":1344},"Pfizer CT.gov Call Center","STUDY_DIRECTOR",[],[1347],{"label":1348,"url":1349},"To obtain contact information for a study center near you, click here.","https:\u002F\u002Fpmiform.com\u002Fclinical-trial-info-request?StudyID=C6491008",{"nct_id":4,"conditions":1351,"biomarkers":1353},[19,1352],"Type 2 Diabetes Mellitus",[],{"nct_id":4,"found":15,"summary":1355,"prompt_version":1365},{"design":1356,"status":1357,"heading":1358,"summary":1359,"follow_up":1360,"word_count":1361,"commitments":1362,"compensation":1363,"drugs_mentioned":1364},"This is an interventional study with an unclear phase, planning to enroll 1044 participants. About two-thirds of participants will receive PF-08653944, and one-third will receive a placebo.","completed","PF-08653944 for Obesity or Overweight and Type 2 Diabetes","This study is looking into the safety and effects of a medicine called PF-08653944 for adults who have obesity (carrying too much body weight) or are overweight, and also have type 2 diabetes (too much sugar in the blood). You could join if you are 18 or older, have a BMI of 27.0 kg\u002Fm2 or higher, and have had type 2 diabetes for at least 6 months with an HbA1c between 6.5% and 10.0%. The medicine, PF-08653944, is given as a shot under the skin once a week. Some participants will receive PF-08653944, while others will receive a placebo (a shot with no medicine). The main goal is to see how much your body weight changes from the start of the study to Week 64. The current recruitment status is unclear.","Participants will be followed for changes in body weight up to Week 64.",131,"You would receive weekly subcutaneous injections of either PF-08653944 or a placebo, which you would be trained to do at home. Your body weight will be measured at the beginning of the study and again at Week 64.","Not stated in the trial record.",[46,56],"v2"]