[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07527871":3,"trial-entities:NCT07527871":100,"trial-summary:NCT07527871":104},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":20,"study_type":22,"primary_purpose":23,"phases":24,"enrollment_info":26,"interventions":29,"primary_outcomes":39,"secondary_outcomes":44,"sex":62,"minimum_age":63,"maximum_age":17,"healthy_volunteers":64,"eligibility_criteria":65,"std_ages":80,"locations":83,"central_contacts":93,"overall_officials":94,"references":98,"see_also_links":99},"NCT07527871","STUDY2025-00000054","Emergency Department-Substance Use Screening, Motivational Interviewing and Active Referral Targeting Substance Use Disorder and Overdose Prevention","ED-SMART: Emergency Department-Substance Use Screening, Motivational Interviewing and Active Referral Targeting Substance Use Disorder and Overdose Prevention","ENROLLING_BY_INVITATION","2029-09","2026-07","2026-07-23","2026-06-17","Purdue University","OTHER",true,"The purpose of this research study is to learn if an emergency department screening and telehealth intervention reduces substance use among individuals receiving emergency department treatment at The Ohio State University Wexner Medical Center.",null,[19],"Substance Use (Drugs, Alcohol)",[21],"substance use","INTERVENTIONAL","TREATMENT",[25],"NA",{"count":27,"type":28},650,"ESTIMATED",[30,35],{"type":31,"name":32,"description":33,"armGroupLabels":34},"BEHAVIORAL","ED-SMART intervention","The ED-SMART intervention will include: (i) a brief (approximately 15 minutes) counseling session in the emergency department and (ii) five, monthly brief counseling sessions (approximately 15 to 30 minutes) delivered by telehealth. These sessions will focus on creating individualized strategies to help participants reach their alcohol and substance use reduction goals",[32],{"type":31,"name":36,"description":37,"armGroupLabels":38},"Substance use information","The substance use information condition will receive printed health information covering information about substance use (e.g., definitions, hazards, potential for addiction, injury, and other consequences). Research staff will also discuss ways to utilize primary care or establish care with a primary care provider to provide ongoing follow-up.",[36],[40],{"measure":41,"description":42,"timeFrame":43},"Self-reported substance use","Self-reported substance use frequency","From baseline to the sixth month follow-up assessment",[45,49,52,56,59],{"measure":46,"description":47,"timeFrame":48},"Self-reported substance use quantity","Self-reported substance use quantity for each substance","From baseline to the six month follow-up",{"measure":50,"description":51,"timeFrame":48},"Incidence of positive substance use disorder screen","Incidence of positive substance use disorder screen as measured by the NIDA Modified ASSIST or AUDIT",{"measure":53,"description":54,"timeFrame":55},"Toxicology assays for substance use","Proportion with positive toxicology assay for substance use","From baseline to the six month follow-up assessment",{"measure":57,"description":57,"timeFrame":58},"Self-reported healthcare utilization","Baseline to the six month follow-up assessment",{"measure":60,"description":61,"timeFrame":58},"Fatal and non-fatal overdose","Frequency of fatal and non-fatal overdose","ALL","18 Years",false,{"inclusion":66,"exclusion":70,"raw_text":79},[67,68,69],"Adult at least 18 years of age","Capacity and willingness to participate (including reliable phone or internet access for counseling session)","Lower or Moderate Risk score on one or more substance use types on National Institute on Drug Abuse (NIDA)-Modified Alcohol, Smoking, and Substance Use Involvement Test (ASSIST). Participants may also endorse alcohol use in conjunction with substance use as indicated by an Alcohol Use Disorder Identification Test-Concise (AUDIT-C) score of Moderate Risk.",[71,72,73,74,75,76,77,78],"A priori participant request for participation","Previously enrolled in this or other study of substance use disorder prevention","Language other than English","Expected\u002Factual ED disposition of hospitalization or non-independent status","Prisoner at time of enrollment","Known to be pregnant at time of enrollment","Past substance use disorder or substance use treatment","High risk score for one or more substances on the NIDA-Modified ASSIST or problematic alcohol use alone","Inclusion Criteria:\n\n* Adult at least 18 years of age\n* Capacity and willingness to participate (including reliable phone or internet access for counseling session)\n* Lower or Moderate Risk score on one or more substance use types on National Institute on Drug Abuse (NIDA)-Modified Alcohol, Smoking, and Substance Use Involvement Test (ASSIST). Participants may also endorse alcohol use in conjunction with substance use as indicated by an Alcohol Use Disorder Identification Test-Concise (AUDIT-C) score of Moderate Risk.\n\nExclusion Criteria:\n\n* A priori participant request for participation\n* Previously enrolled in this or other study of substance use disorder prevention\n* Language other than English\n* Expected\u002Factual ED disposition of hospitalization or non-independent status\n* Prisoner at time of enrollment\n* Known to be pregnant at time of enrollment\n* Past substance use disorder or substance use treatment\n* High risk score for one or more substances on the NIDA-Modified ASSIST or problematic alcohol use alone",[81,82],"ADULT","OLDER_ADULT",[84],{"facility":85,"city":86,"state":87,"zip":88,"country":89,"geoPoint":90},"The Ohio State University Wexner Medical Center","Columbus","Ohio","43201","United States",{"lat":91,"lon":92},39.96118,-82.99879,[],[95],{"name":96,"affiliation":13,"role":97},"Jennifer L. Brown, PhD","PRINCIPAL_INVESTIGATOR",[],[],{"nct_id":4,"conditions":101,"biomarkers":103},[102],"Substance use disorder",[],{"nct_id":4,"found":15,"summary":105,"prompt_version":115},{"design":106,"status":107,"heading":108,"summary":109,"follow_up":110,"word_count":111,"commitments":112,"compensation":113,"drugs_mentioned":114},"This interventional study plans to enroll 650 participants. It compares a behavioral intervention (ED-SMART) with receiving substance use information.","completed","Emergency Department Intervention for Substance Use","This study is looking at whether an emergency department screening and telehealth program, called ED-SMART, can help reduce substance use. The ED-SMART program involves brief counseling sessions in the emergency department and then monthly telehealth sessions. Another group will receive printed information about substance use. The study aims to see if these interventions reduce how often people report using substances over six months. You might be able to join if you are an adult aged 18 or older, can participate reliably (with phone or internet), and have a lower or moderate risk score for substance use based on a screening test. The study is currently unclear about its recruitment status and is taking place at The Ohio State University Wexner Medical Center.","Participants will be followed for six months after the start of the study to assess self-reported substance use.",122,"You would participate in a brief counseling session in the emergency department, followed by five monthly brief counseling sessions delivered by telehealth. The study will track your self-reported substance use for six months.","Not stated in the trial record.",[],"v2"]