[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07564388":3,"trial-entities:NCT07564388":88,"trial-summary:NCT07564388":92},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":16,"conditions":17,"keywords":19,"study_type":22,"primary_purpose":23,"phases":24,"enrollment_info":26,"interventions":29,"primary_outcomes":36,"secondary_outcomes":53,"sex":54,"minimum_age":55,"maximum_age":56,"healthy_volunteers":57,"eligibility_criteria":58,"std_ages":71,"locations":74,"central_contacts":84,"overall_officials":85,"references":86,"see_also_links":87},"NCT07564388","STU00223538","Cochlear-Implant-Performance-Prediction","ENROLLING_BY_INVITATION","2027-12-31","2026-05","2026-05-29","2025-06-25","Northwestern University","OTHER",false,"Despite improved technology, many cochlear implant (CI) recipients still struggle to understand speech in noise (SIN). Because the bottom-up acoustic signal generated by the implant is distorted relative to normal-hearing acoustic input, CI users rely more on top-down processing to decipher masked speech. To better predict outcomes for CI recipients, top-down auditory processing ability should be assessed. However, hearing impairment makes testing top-down auditory processing ability through auditory means difficult. The study aims to determine whether testing visual top-down processing can predict auditory top-down processing capability.","Participants will complete a proctored, 25-minute computer-based test battery of visual cognitive tests (Stroop Test, Trail-Making Tests), visual distorted-signal tests (Scrambled Letters, VisualSNR), and auditory threshold tests (QuickSIN, Hearing Test). To prevent the accumulation of mental fatigue, tests will be administered in a predetermined order designed to minimize it. Including time for explanations for each test and questions from the participant about the testing protocol, the total time the participant will spend on the study is approximately 45 minutes.",[18],"Performance Prediction",[20,21],"Cochlear implants","user performance prediction","INTERVENTIONAL","DIAGNOSTIC",[25],"NA",{"count":27,"type":28},60,"ESTIMATED",[30],{"type":31,"name":32,"description":33,"armGroupLabels":34},"DIAGNOSTIC_TEST","cochlear implant user performance prediction","A battery of visual cognitive tests will be combined to identify a set of tests that can predict user performance in speech-in-noise and music perception.",[35],"performance assessment",[37,41,44,47,50],{"measure":38,"description":39,"timeFrame":40},"SNR-loss (dB)","The Quick Sound-in-Noise (QuickSIN) test is a common method for assessing speech-in-noise perception. In this test, participants listen to sentences spoken by a female speaker in increasingly loud four-talker babble. The signal-to-noise ratio (SNR) loss for two QuickSIN tests will be averaged and recorded.","baseline",{"measure":42,"description":43,"timeFrame":40},"Audiogram","Behavioral hearing threshold",{"measure":45,"description":46,"timeFrame":40},"Stroop times","The Stroop Test assesses inhibition-concentration. This test consists of two sets of subtests. Each subtest requires reading 25 words from a table of colored words: the first subtest requires the participant to read the word, and the second requires the participant to name the color of the word. In the first set of subtests, the words will be colored corresponding to the meaning of the color word (i.e. 'Red' will be colored red). In the second set of subtests, the words will be colored in a different color than the meaning of the word (i.e.' Red' will be colored purple). The completion time of each subtest will be recorded.",{"measure":48,"description":49,"timeFrame":40},"Trail times","The Trail-Making Test (TMT) assesses attention and processing speed. This test consists of subtests A and B. In part A, the participant must connect dots numbered 1-25 in numerical order. In part B, the participant must connect dots numbered 1-13 and dots labeled A-L in alternating order (i.e. 1-A-2-B). If the participant makes a mistake, they must correct the mistake before moving on. The completion time of each subtest will be recorded.",{"measure":51,"description":52,"timeFrame":40},"Percent identified","The Scrambled Letters and VisualSNR tests were developed to assess the participant's ability to decipher garbled or distorted visual stimuli.",[],"ALL",null,"18 Years",true,{"inclusion":59,"exclusion":60,"raw_text":70},[],[61,62,63,64,65,66,67,68,69],"Individuals who are not yet adults (infants, children, teenage children),","Adults unable to consent,","Adults with known impaired decision-making capacity,","Pregnant women,","Prisoners (or other detained\u002Fparoled individuals),","Students or postdoctoral trainees who are taught by or academically mentored by the Principal Investigator, in compliance with the Enrollment of Students and Trainees in Research Studies policies.","Non-fluent English speakers, Tests (specifically Scrambled Letters and QuickSIN) require proficiency in the English language.","Individuals with severe hearing impairment, Tests (specifically QuickSIN) require participants to not have trouble hearing speech.","Individuals with significant, uncorrected visual impairment. All visual tests require the participant to be able to read medium-sized text on a screen approximately two feet in front of them.","Inclusion Criteria:\n\n* All participants who do not fit the exclusion criteria.\n\nExclusion Criteria:\n\n* Individuals who are not yet adults (infants, children, teenage children),\n* Adults unable to consent,\n* Adults with known impaired decision-making capacity,\n* Pregnant women,\n* Prisoners (or other detained\u002Fparoled individuals),\n* Students or postdoctoral trainees who are taught by or academically mentored by the Principal Investigator, in compliance with the Enrollment of Students and Trainees in Research Studies policies.\n* Non-fluent English speakers, Tests (specifically Scrambled Letters and QuickSIN) require proficiency in the English language.\n* Individuals with severe hearing impairment, Tests (specifically QuickSIN) require participants to not have trouble hearing speech.\n* Individuals with significant, uncorrected visual impairment. All visual tests require the participant to be able to read medium-sized text on a screen approximately two feet in front of them.",[72,73],"CHILD","ADULT",[75],{"facility":76,"city":77,"state":78,"zip":79,"country":80,"geoPoint":81},"Northwestern Univeristy","Chicago","Illinois","60611","United States",{"lat":82,"lon":83},41.85003,-87.65005,[],[],[],[],{"nct_id":4,"conditions":89,"biomarkers":91},[90],"Implantation of cochlear prosthetic device",[],{"nct_id":4,"found":14,"summary":55,"prompt_version":55}]