[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07643545":3,"trial-entities:NCT07643545":94,"trial-summary:NCT07643545":98},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":16,"conditions":17,"keywords":19,"study_type":20,"primary_purpose":16,"phases":21,"enrollment_info":22,"interventions":25,"primary_outcomes":26,"secondary_outcomes":31,"sex":34,"minimum_age":35,"maximum_age":36,"healthy_volunteers":14,"eligibility_criteria":37,"std_ages":52,"locations":56,"central_contacts":81,"overall_officials":89,"references":92,"see_also_links":93},"NCT07643545","263136","Mitochondrial Energy Metabolism in Burns","The Role of the Mitochondrian in the Metabolic Stress Response to Burn Trauma","RECRUITING","2026-06","2026-06-11","2023-04-20","Arkansas Children's Hospital Research Institute","OTHER",false,"The goal of this observational study is to assess the impact of burn injury on cellular energetics in patients that have been admitted to the burn center at Arkansas Children's Hospital for burn care and require one or more procedures to clean, debride, and repair burn wounds will be eligible to participate in this study.\n\nDuring the study, we will collect the following information:\n\n* General background information such as date of birth, height, weight, and other basic information.\n* Medical information, such as: basic medical information, details of burn injury, vital signs on the day of surgery, medicines you take during your stay, and some clinical tests.\n* Blood, urine, and tissue during surgeries you have during your stay.",null,[18],"Burn Injury",[],"OBSERVATIONAL",[],{"count":23,"type":24},125,"ESTIMATED",[],[27],{"measure":28,"description":29,"timeFrame":30},"Blood Bioenergetics","Peripheral Blood Mononuclear Cell (PBMC) respiration","Through study completion, an average of 1 year",[32],{"measure":33,"description":29,"timeFrame":30},"Blood metabolics signatures","ALL","2 Years","80 Years",{"inclusion":38,"exclusion":44,"raw_text":51},[39,40,41,42,43],"Male or Female","Ages 2 years to 80 years","Requiring hospital admission for burn care","All races","All ethnicities",[45,46,47,48,49,50],"Age \\\u003C 2 years","Under 10 kg in body mass","Age \\> 80 years","Active pregnancy","Unable to provide informed consent and no legal authorized representative present","Patient is considered moribund at the time of admission by the treating physician.","Inclusion Criteria:\n\n* Male or Female\n* Ages 2 years to 80 years\n* Requiring hospital admission for burn care\n* All races\n* All ethnicities\n\nExclusion Criteria:\n\n* Age \\\u003C 2 years\n* Under 10 kg in body mass\n* Age \\> 80 years\n* Active pregnancy\n* Unable to provide informed consent and no legal authorized representative present\n* Patient is considered moribund at the time of admission by the treating physician.",[53,54,55],"CHILD","ADULT","OLDER_ADULT",[57],{"facility":58,"status":8,"city":59,"state":60,"zip":61,"country":62,"contacts":63,"geoPoint":78},"Arkansas Children's Hospital","Little Rock","Arkansas","72202","United States",[64,67,70,72,74,76],{"name":65,"role":66},"Craig Porter, PhD","PRINCIPAL_INVESTIGATOR",{"name":68,"role":69},"Esther Teo, MD","SUB_INVESTIGATOR",{"name":71,"role":69},"Robert Maxson, MD",{"name":73,"role":69},"Richard Yeager, MD",{"name":75,"role":69},"Daniel Lozano, MD",{"name":77,"role":69},"Mandy Yelvington, MS, OTR\u002FL",{"lat":79,"lon":80},34.74648,-92.28959,[82,86],{"name":65,"role":83,"phone":84,"email":85},"CONTACT","5013643340","cporter@uams.edu",{"name":87,"role":83,"phone":84,"email":88},"Lily Cheak, B.S.","lcheak@uams.edu",[90],{"name":65,"affiliation":91,"role":66},"Arkansas Children's Research Institute",[],[],{"nct_id":4,"conditions":95,"biomarkers":97},[96],"Burn",[],{"nct_id":4,"found":14,"summary":16,"prompt_version":16}]