[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07649031":3,"trial-entities:NCT07649031":14,"trial-summary:NCT07649031":14},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":14,"conditions":16,"keywords":18,"study_type":19,"primary_purpose":14,"phases":20,"enrollment_info":21,"interventions":24,"primary_outcomes":32,"secondary_outcomes":40,"sex":41,"minimum_age":42,"maximum_age":14,"healthy_volunteers":43,"eligibility_criteria":44,"std_ages":55,"locations":58,"central_contacts":73,"overall_officials":75,"references":79,"see_also_links":80},"NCT07649031","DENT-2025-34242, STUDY00027283","MRI as Noninvasive Innovative Approach in Detection and Monitoring of Malignant Oral Lesions in Fanconi Anemia Patients","RECRUITING","2030-05-31","2026-06","2026-07-02","2026-06-23","University of Minnesota","OTHER",null,"This study being done to learn more about the use of medical Magnetic Resonance Imaging (mMRI) and dedicated dental MRI (ddMRI) as a non-invasive diagnosing tool when evaluating potential oral cancerous and precancerous lesions in Fanconi Anemia patients.",[17],"Fanconi Anemia",[],"OBSERVATIONAL",[],{"count":22,"type":23},80,"ESTIMATED",[25],{"type":26,"name":27,"description":28,"armGroupLabels":29},"DIAGNOSTIC_TEST","MRIs","mMRI and ddMRI",[30,31],"FA patients with a history of HNSCC","FA patients with no history of HNSCC",[33,37],{"measure":34,"description":35,"timeFrame":36},"sensitivity of mMRI and ddMRI in identifying dysplastic and malignant lesions in FA patients.","Proportion of positive lesions correctly diagnosed","Immediately after MRI",{"measure":38,"description":39,"timeFrame":36},"specificity of mMRI and ddMRI in identifying dysplastic and malignant lesions in FA patients.","Proportion of negative lesions correctly diagnosed",[],"ALL","18 Years",false,{"inclusion":45,"exclusion":48,"raw_text":54},[46,47],"Patients with a diagnosis of Fanconi Anemia who are willing to participate and willing to have MRIs","Willing to provide informed consent",[49,50,51,52,53],"Patient without diagnosis of FA","Patients with FA who are under the age of 18","Unable to tolerate any MRI due to claustrophobia","Any contraindication for the MRI","Unable to provide informed consent or comply with the study protocol","Inclusion Criteria:\n\n* Patients with a diagnosis of Fanconi Anemia who are willing to participate and willing to have MRIs\n* Willing to provide informed consent\n\nExclusion Criteria:\n\n* Patient without diagnosis of FA\n* Patients with FA who are under the age of 18\n* Unable to tolerate any MRI due to claustrophobia\n* Any contraindication for the MRI\n* Unable to provide informed consent or comply with the study protocol",[56,57],"ADULT","OLDER_ADULT",[59],{"facility":12,"status":7,"city":60,"state":61,"zip":62,"country":63,"contacts":64,"geoPoint":70},"Minneapolis","Minnesota","55455","United States",[65],{"name":66,"role":67,"phone":68,"email":69},"Carla Campbell, BS","CONTACT","612-625-6976","camp2757@umn.edu",{"lat":71,"lon":72},44.97997,-93.26384,[74],{"name":66,"role":67,"phone":68,"email":69},[76],{"name":77,"affiliation":12,"role":78},"Rachel Uppgaard","PRINCIPAL_INVESTIGATOR",[],[]]