[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07663539":3,"trial-entities:NCT07663539":83,"trial-summary:NCT07663539":86},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":20,"study_type":24,"primary_purpose":25,"phases":26,"enrollment_info":27,"interventions":30,"primary_outcomes":31,"secondary_outcomes":36,"sex":37,"minimum_age":38,"maximum_age":25,"healthy_volunteers":25,"eligibility_criteria":39,"std_ages":52,"locations":55,"central_contacts":72,"overall_officials":74,"references":76,"see_also_links":77},"NCT07663539","FOCUS","Insights From Bereaved Parents and Oncologists","Foundations of Communication in Uncertainty Study (FOCUS): Insights From Bereaved Parents and Oncologists","RECRUITING","2026-12","2026-07","2026-07-28","2026-07-09","St. Jude Children's Research Hospital","OTHER",false,"Investigators want to find better ways for doctors and families to talk about cancer and how uncertainty may affect a child's life.","Primary Objective\n\n* To characterize how bereaved parents of children with cancer and their child's oncologist perceive their experience with communication about prognostic uncertainty during the child's cancer journey and during bereavement.\n\nSecondary Objective\n\n* To elicit parents' and oncologists' preferences and recommendations for how clinicians should talk with children and families about prognosis in the setting of uncertainty.\n\nThis study aims to explore bereaved parents' and oncologists' reflections on communication about prognostic uncertainty during the child's cancer treatment. Parents who have lost a child to cancer and the doctors who treated them will be invited to join this study.\n\nParticipants who opt to participate in the study will engage in an audio recorded semi-structured interview with a researcher, virtually or in person (at their discretion) to share their perspectives and recommendations based on their experience. Throughout the interview, the interviewer has the option to ask additional questions (i.e., probe with questions not in the interview guide) to respond to comments made by the participant and honor the topics of interest to that given participant. The participant will be provided an opportunity to add any details or comments at the end of the interview if he\u002Fshe would like to share additional information.\n\nFollowing completion of the qualitative portion of the interview, the researcher will ask the participant several questions from a demographic form. The demographic form will include questions related to participant age, race\u002Fethnicity, state\u002Fcountry of residence for bereaved parents, and years of clinical practice for oncologists.",[19],"Communication",[21,22,23],"Prognostic Uncertainty","Bereaved Parents","Oncologist","OBSERVATIONAL",null,[],{"count":28,"type":29},50,"ESTIMATED",[],[32],{"measure":33,"description":34,"timeFrame":35},"Bereaved parents of children with cancer and oncologists reflections on communication about prognostic uncertainty during the child's cancer treatment","The analysis plan for this study is to apply reflexive thematic analysis as described by Braun and Clarke, involving the following six step process: 1. Familiarization with the data, 2. Generating initial codes, 3. Generating initial themes, 4. Reviewing themes, 5. Refining, defining, and naming themes, 6. Writing up a narrative of results. Investigators will conduct individual interviews with participants and code transcripts independently to identify salient themes from each cohort, subsequently compare codes across cohorts to explore and characterize areas of convergence and divergence and use a matrix approach to facilitate this comparative analysis.\n\nInterviews will be recorded, transcribed, and de-identified prior to analysis. MAXQDA, a sophisticated qualitative analysis software system, will be used to conduct and synthesize analysis.","Approximately 1-3 weeks after enrollment.",[],"ALL","18 Years",{"inclusion":40,"exclusion":48,"raw_text":51},[41,42,43,44,45,46,47],"All participants must be ≥ 18 years of age or legally emancipated","Parent Participants must have a child who:","Received cancer care from a clinician at St. Jude, as documented in the electronic medical record, AND","Died at least 6 months prior to enrollment, but no more than 24 months prior to enrollment.","Oncologist participants at St. Jude must:","Be listed as the primary oncologist as documented in the electronic medical record, AND","Have the respective patient's parent agreement to participate in the study.",[49,50],"Declining, refusal, or unwillingness to participate","Inability or unwillingness of research participant to give informed consent.","Inclusion Criteria:\n\n* All participants must be ≥ 18 years of age or legally emancipated\n* Parent Participants must have a child who:\n\n  * Received cancer care from a clinician at St. Jude, as documented in the electronic medical record, AND\n  * Died at least 6 months prior to enrollment, but no more than 24 months prior to enrollment.\n* Oncologist participants at St. Jude must:\n\n  * Be listed as the primary oncologist as documented in the electronic medical record, AND\n  * Have the respective patient's parent agreement to participate in the study.\n\nExclusion Criteria:\n\n* Declining, refusal, or unwillingness to participate\n* Inability or unwillingness of research participant to give informed consent.",[53,54],"ADULT","OLDER_ADULT",[56],{"facility":13,"status":8,"city":57,"state":58,"zip":59,"country":60,"contacts":61,"geoPoint":69},"Memphis","Tennessee","38105","United States",[62,67],{"name":63,"role":64,"phone":65,"email":66},"Stephanie Gehle, MD","CONTACT","888-226-4343","referralinfo@stjude.org",{"name":63,"role":68},"PRINCIPAL_INVESTIGATOR",{"lat":70,"lon":71},35.14953,-90.04898,[73],{"name":63,"role":64,"phone":65,"email":66},[75],{"name":63,"affiliation":13,"role":68},[],[78,80],{"label":13,"url":79},"http:\u002F\u002Fwww.stjude.org",{"label":81,"url":82},"Clinical Trials Open at St. Jude","http:\u002F\u002Fwww.stjude.org\u002Fprotocols",{"nct_id":4,"conditions":84,"biomarkers":85},[],[],{"nct_id":4,"found":87,"summary":88,"prompt_version":98},true,{"design":89,"status":90,"heading":91,"summary":92,"follow_up":93,"word_count":94,"commitments":95,"compensation":96,"drugs_mentioned":97},"This is an observational study, meaning researchers will gather information without giving any specific treatments. It aims to include 50 participants.","completed","Understanding Communication About Uncertainty in Childhood Cancer","This study wants to understand how parents who have lost a child to cancer and the doctors who treated them talk about the child's future when things are uncertain. Researchers want to learn how these conversations happen during treatment and after a child has passed away. They also want to find out what parents and doctors think are the best ways to have these difficult conversations. You might be able to join if you are an adult parent whose child received cancer care at St. Jude and passed away between 6 and 24 months ago, or if you are an oncologist at St. Jude. The study hopes to enroll 50 people. Success for this study means gathering reflections from parents and oncologists about their experiences with communication about prognostic uncertainty.","Not specified.",130,"If you choose to participate, you will have an audio-recorded interview with a researcher, either online or in person. You will share your thoughts and recommendations based on your experiences.","Not stated in the trial record.",[],"v2"]