[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07682610":3,"trial-entities:NCT07682610":221,"trial-summary:NCT07682610":225},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":15,"conditions":17,"keywords":19,"study_type":20,"primary_purpose":21,"phases":22,"enrollment_info":24,"interventions":27,"primary_outcomes":34,"secondary_outcomes":39,"sex":40,"minimum_age":41,"maximum_age":42,"healthy_volunteers":43,"eligibility_criteria":44,"std_ages":55,"locations":58,"central_contacts":215,"overall_officials":218,"references":219,"see_also_links":220},"NCT07682610","MCC-25-KQUILS-PT","Kentucky - Quality Improvement Implementation Lung Cancer Screening (QUILS™) Health Services Research Intervention","Statewide Optimization of Lung Cancer Screening Utilizing the QUILS™ System (Kentucky QUILS™ Implementation): HSR Intervention","RECRUITING","2028-06-01","2026-06","2026-07-06","2025-04-01","Timothy Mullett","OTHER",null,"This clinical trial studies statewide optimization of lung cancer screening (LCS) in Kentucky using the Quality Implementation of Lung Screening (QUILS™) System. Data from the Kentucky Cancer Registry shows that LCS implementation has contributed to a rapid decline in late-stage lung cancer diagnosis at twice the national average. Further, the declines are more than three times the national average decline in Kentucky's Central Appalachian region. Kentucky-based multilevel initiatives are needed to expand and accelerate this leading role and extend the LCS opportunity to more Kentuckians who are at increased risk of lung cancer. This trial may be able to accelerate optimal high-quality implementation of LCS utilizing the QUILS™ System and reduce the burden of lung cancer by assisting lung cancer screening programs located throughout Kentucky in implementing best practices in lung cancer screening by integrating the QUILS™ System domains and elements into their screening programs.",[18],"Lung Cancer Screening",[],"INTERVENTIONAL","HEALTH_SERVICES_RESEARCH",[23],"NA",{"count":25,"type":26},35500,"ESTIMATED",[28],{"type":29,"name":30,"description":31,"armGroupLabels":32},"BEHAVIORAL","Quality Implementation of Lung Cancer Screening (QUILS) System","The QUILS System is a health services research intervention designed to improve the quality of lung cancer screening programs. The intervention includes QUILS Index Assessment, QUILS Audit and Feedback Report and Presentation, QUILS Resource Portal, site-specific action plans, and formative evaluation activities.",[33],"QUILS System Implementation",[35],{"measure":36,"description":37,"timeFrame":38},"Change in Quality Improvement Lung Cancer Screening (QUILS) Index Assessment Score","The QUILS Index Assessment is a program-level measure of lung cancer screening implementation quality. Scores range from 0 to 95, with a higher score indicating higher quality implementation of lung cancer screening practices. The outcome measure is the change in total QUILS Index score from Baseline to 12 months.","Baseline and Month 9",[],"ALL","18 Years","100 Years",true,{"inclusion":45,"exclusion":50,"raw_text":54},[46,47,48,49],"Member of a participating Lung Cancer Screening Program (LCSP) team or administrator","Willing to participate in the QUILS Index Assessment Survey process","Willing to participate in the QUILS Audit Feedback presentations","Willing to participate in formative evaluation interviews",[51,52,53],"Unwilling to participate in the QUILS Index Assessment Survey process","Unwilling to participate in the QUILS Audit Feedback presentations","Unwilling to participate in formative evaluation interviews","Inclusion Criteria:\n\n* Member of a participating Lung Cancer Screening Program (LCSP) team or administrator\n* Willing to participate in the QUILS Index Assessment Survey process\n* Willing to participate in the QUILS Audit Feedback presentations\n* Willing to participate in formative evaluation interviews\n\nExclusion Criteria:\n\n* Unwilling to participate in the QUILS Index Assessment Survey process\n* Unwilling to participate in the QUILS Audit Feedback presentations\n* Unwilling to participate in formative evaluation interviews",[56,57],"ADULT","OLDER_ADULT",[59,74,83,92,102,111,120,129,135,142,151,160,169,178,188,197,206],{"facility":60,"status":8,"city":61,"state":62,"zip":63,"country":64,"contacts":65,"geoPoint":71},"King's Daughter's Medical Center","Ashland","Kentucky","41101","United States",[66],{"name":67,"role":68,"phone":69,"email":70},"Joseph Alexander","CONTACT","8593230892","joseph.alexander@uky.edu",{"lat":72,"lon":73},38.47841,-82.63794,{"facility":75,"status":8,"city":76,"state":62,"zip":77,"country":64,"contacts":78,"geoPoint":80},"Taylor Regional Hospital","Campbellsville","42718",[79],{"name":67,"role":68,"phone":69,"email":70},{"lat":81,"lon":82},37.3434,-85.34191,{"facility":84,"status":8,"city":85,"state":62,"zip":86,"country":64,"contacts":87,"geoPoint":89},"St. Elizabeth Healthcare","Edgewood","41017",[88],{"name":67,"role":68,"phone":69,"email":70},{"lat":90,"lon":91},39.01867,-84.58189,{"facility":93,"status":8,"city":94,"state":62,"zip":95,"country":64,"contacts":96,"geoPoint":99},"Georgetown Cancer Treatment Cancer","Georgetown","40324",[97],{"name":67,"role":68,"phone":98,"email":70},"859-323-0892",{"lat":100,"lon":101},38.2098,-84.55883,{"facility":103,"status":8,"city":104,"state":62,"zip":105,"country":64,"contacts":106,"geoPoint":108},"TJ Samson Community Hospital","Glasgow","42141",[107],{"name":67,"role":68,"phone":69,"email":70},{"lat":109,"lon":110},36.99588,-85.91192,{"facility":112,"status":8,"city":113,"state":62,"zip":114,"country":64,"contacts":115,"geoPoint":117},"Hazard Appalachian Regional Healthcare Medical Center","Hazard","41701",[116],{"name":67,"role":68,"phone":69,"email":70},{"lat":118,"lon":119},37.24954,-83.19323,{"facility":121,"status":8,"city":122,"state":62,"zip":123,"country":64,"contacts":124,"geoPoint":126},"Lexington VA Health Care System","Lexington","40502",[125],{"name":67,"role":68,"phone":69,"email":70},{"lat":127,"lon":128},37.98869,-84.47772,{"facility":130,"status":8,"city":122,"state":62,"zip":131,"country":64,"contacts":132,"geoPoint":134},"St. Joseph Health (Catholic Health Initiatives)","40504",[133],{"name":67,"role":68,"phone":69,"email":70},{"lat":127,"lon":128},{"facility":136,"status":8,"city":122,"state":62,"zip":137,"country":64,"contacts":138,"geoPoint":141},"University of Kentucky Markey Cancer Center","40506",[139],{"role":68,"email":140},"jill.cole1@uky.edu",{"lat":127,"lon":128},{"facility":143,"status":8,"city":144,"state":62,"zip":145,"country":64,"contacts":146,"geoPoint":148},"The James Graham Brown Cancer Center at University of Louisville","Louisville","40202",[147],{"name":67,"role":68,"phone":69,"email":70},{"lat":149,"lon":150},38.25424,-85.75941,{"facility":152,"status":8,"city":153,"state":62,"zip":154,"country":64,"contacts":155,"geoPoint":157},"Meadowview Regional Medical Center","Maysville","41056",[156],{"name":67,"role":68,"phone":69,"email":70},{"lat":158,"lon":159},38.64119,-83.74437,{"facility":161,"status":8,"city":162,"state":62,"zip":163,"country":64,"contacts":164,"geoPoint":166},"Saint Claire Regional Medical Center","Morehead","40351",[165],{"name":67,"role":68,"phone":69,"email":70},{"lat":167,"lon":168},37.27115,-87.17638,{"facility":170,"status":8,"city":171,"state":62,"zip":172,"country":64,"contacts":173,"geoPoint":175},"Rockcastle Regional Hospital","Mount Vernon","40456",[174],{"name":67,"role":68,"phone":69,"email":70},{"lat":176,"lon":177},38.02563,-84.49522,{"facility":179,"status":8,"city":180,"state":62,"zip":181,"country":64,"contacts":182,"geoPoint":185},"Owensboro Health Mitchell Memorial Cancer Center","Owensboro","42303",[183],{"name":184,"role":68,"phone":69,"email":70},"Jospeh Alexander",{"lat":186,"lon":187},37.77422,-87.11333,{"facility":189,"status":8,"city":190,"state":62,"zip":191,"country":64,"contacts":192,"geoPoint":194},"Mercy Health - Paducah Cancer Center","Paducah","42003",[193],{"name":67,"role":68,"phone":69,"email":70},{"lat":195,"lon":196},37.08339,-88.60005,{"facility":198,"status":8,"city":199,"state":62,"zip":200,"country":64,"contacts":201,"geoPoint":203},"Lake Cumberland Regional Hospital","Somerset","42501",[202],{"name":67,"role":68,"phone":69,"email":70},{"lat":204,"lon":205},37.09202,-84.60411,{"facility":207,"status":8,"city":208,"state":62,"zip":209,"country":64,"contacts":210,"geoPoint":212},"Clark Regional Medical Center","Winchester","40391",[211],{"name":67,"role":68,"phone":98,"email":70},{"lat":213,"lon":214},37.99008,-84.17965,[216],{"name":217,"role":68,"phone":69,"email":70},"Joseph Alexander, MD",[],[],[],{"nct_id":4,"conditions":222,"biomarkers":224},[223],"Lung Carcinoma",[],{"nct_id":4,"found":43,"summary":226,"prompt_version":235},{"design":227,"status":228,"heading":6,"summary":229,"follow_up":230,"word_count":231,"commitments":232,"compensation":233,"drugs_mentioned":234},"This is an interventional study with a planned enrollment of 35,500 participants. It is not specified if it is randomized or blinded.","completed","This study is looking at how to improve lung cancer screening programs across Kentucky using a system called QUILS™ (Quality Implementation of Lung Cancer Screening). The QUILS™ System includes assessments, feedback reports, and resources to help screening programs work better. The goal is to expand and speed up lung cancer screening for more Kentuckians who are at higher risk. You can join if you are part of a lung cancer screening team or an administrator, are willing to complete surveys, and participate in feedback presentations and interviews. The study will measure success by looking at changes in the QUILS Index Assessment Score over nine months. The current recruitment status is unclear, and the study plans to enroll 35,500 participants.","The primary endpoint is measured at Baseline and Month 9, suggesting a follow-up period of at least nine months.",119,"You would participate in the QUILS Index Assessment Survey process, QUILS Audit Feedback presentations, and formative evaluation interviews.","Not stated in the trial record.",[],"v2"]