[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07692945":3,"trial-entities:NCT07692945":85,"trial-summary:NCT07692945":88},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":20,"study_type":21,"primary_purpose":22,"phases":23,"enrollment_info":25,"interventions":28,"primary_outcomes":35,"secondary_outcomes":40,"sex":41,"minimum_age":42,"maximum_age":43,"healthy_volunteers":15,"eligibility_criteria":44,"std_ages":57,"locations":60,"central_contacts":80,"overall_officials":82,"references":83,"see_also_links":84},"NCT07692945","IRB23-1659","Biasing Food Value Construction","Constructing the Subjective Value of Food in Anorexia Nervosa","NOT_YET_RECRUITING","2028-07-31","2026-06","2026-07-09","2026-09-01","University of Chicago","OTHER",true,"The goal of this clinical trial is to examine whether food value construction can be biased in individuals with anorexia nervosa. The main question it aims to answer is:\n\nCan a simple training task increase the importance of relevant food attributes such that subsequent choices about what to eat in individuals with anorexia nervosa will look more like those of healthy eaters?\n\nParticipants will undergo a simple training paradigm where they view food items and focus on different attributes (e.g., its tastiness or healthiness). Participants will then be asked to make decisions about what foods they'd like to eat.",null,[19],"Anorexia Nervosa",[],"INTERVENTIONAL","BASIC_SCIENCE",[24],"NA",{"count":26,"type":27},150,"ESTIMATED",[29],{"type":30,"name":31,"description":32,"armGroupLabels":33},"BEHAVIORAL","Training food attributes","Participants will view images of foods and asked to focus on different attributes of the food (e.g., its healthiness or tastiness)",[19,34],"Healthy Control",[36],{"measure":37,"description":38,"timeFrame":39},"Change in Decision Weight for Tastiness vs. Healthiness Attributes in Food Choice","Food choice will be assessed using a binary choice task in which participants choose between pairs of food items that vary on healthiness, tastiness, savoriness, and overall preference. Choice data will be modeled using mixed-effects logistic regression, with delta-healthiness (difference in healthiness rating between paired items) and delta-tastiness (difference in tastiness rating) entered as predictors of choice. The parameter of interest is the regression coefficient (beta weight) for delta-tastiness relative to delta-healthiness, reflecting the degree to which choice is driven by tastiness versus healthiness attributes. We predict that tastiness beta weight will increase pre- to post-training in patients with AN.","Immediately prior to and immediately following the training session (pre- and post-assessments, approximately 1 hour apart on the same day)",[],"ALL","16 Years","45 Years",{"inclusion":45,"exclusion":49,"raw_text":56},[46,47,48],"aged 16-35 years","male or female","able to read and speak English",[50,51,52,53,54,55],"history of concussion or neurological disease","full scale IQ estimate \\\u003C 80;","taking medication that has been shown to affect attention or learning (i.e., second generation antipsychotics, memantine, methylphenidate, or modafinil)","current psychosis, bipolar disorder, or substance dependence","body mass index \\\u003C 14","vital sign or laboratory abnormalities indicating medical instability","Inclusion Criteria:\n\n* aged 16-35 years\n* male or female\n* able to read and speak English\n\nExclusion Criteria for all participants:\n\n* history of concussion or neurological disease\n* full scale IQ estimate \\\u003C 80;\n* taking medication that has been shown to affect attention or learning (i.e., second generation antipsychotics, memantine, methylphenidate, or modafinil)\n\nExclusion Criteria for participants with anorexia nervosa:\n\n* current psychosis, bipolar disorder, or substance dependence\n* body mass index \\\u003C 14\n* vital sign or laboratory abnormalities indicating medical instability",[58,59],"CHILD","ADULT",[61],{"facility":62,"city":63,"state":64,"zip":65,"country":66,"contacts":67,"geoPoint":77},"The University of Chicago","Chicago","Illinois","60637","United States",[68,73,75],{"name":69,"role":70,"phone":71,"email":72},"Akram Bakkour","CONTACT","773-702-9574","bakkour@uchicago.edu",{"name":69,"role":74},"PRINCIPAL_INVESTIGATOR",{"name":76,"role":74},"Jennifer E Wildes",{"lat":78,"lon":79},41.85003,-87.65005,[81],{"name":69,"role":70,"phone":71,"email":72},[],[],[],{"nct_id":4,"conditions":86,"biomarkers":87},[19],[],{"nct_id":4,"found":15,"summary":89,"prompt_version":99},{"design":90,"status":91,"heading":92,"summary":93,"follow_up":94,"word_count":95,"commitments":96,"compensation":97,"drugs_mentioned":98},"This is an interventional study planning to enroll 150 participants. It involves a behavioral intervention where participants focus on food attributes.","completed","Biasing Food Value Construction for Anorexia Nervosa","This study is looking at whether a simple training task can help people with anorexia nervosa make food choices more like healthy eaters. You would view images of foods and focus on different qualities, like how tasty or healthy they are. Researchers want to see if this training can change how important tastiness versus healthiness is when you decide what to eat. This study is for individuals aged 16 to 45 who can read and speak English. The goal is to see if this training can make food choices more similar to those of healthy eaters. The current recruitment status is unclear.","The primary endpoint is measured immediately following the training session, approximately one hour later.",102,"You would participate in a training session where you view food images and focus on their attributes. Immediately before and after this session, you would complete assessments, all on the same day, approximately one hour apart.","Not stated in the trial record.",[],"v2"]