[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07694739":3,"trial-entities:NCT07694739":98,"trial-summary:NCT07694739":101},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":20,"study_type":21,"primary_purpose":14,"phases":22,"enrollment_info":24,"interventions":27,"primary_outcomes":44,"secondary_outcomes":58,"sex":59,"minimum_age":60,"maximum_age":61,"healthy_volunteers":15,"eligibility_criteria":62,"std_ages":68,"locations":70,"central_contacts":85,"overall_officials":92,"references":96,"see_also_links":97},"NCT07694739","1R01CA300653-01A1","E-cigarette Social Media Marketing and Its Perceptions by Youth","Evolution of Influencer-driven E-cigarette Marketing on Social Media and Its Effect on E-cigarette Perceptions and Use Patterns Among Adolescents","NOT_YET_RECRUITING","2030-12-30","2026-07","2026-07-20","2027-01-01","University of Southern California","OTHER",false,"The proposed study will conduct two randomized between-subject experiments among 6,000 adolescents (per each experiment) recruited nationwide to test the effects of audio-visual features of e-cigarette influencer marketing on perceptions of influencer credibility, e-cigarette harm perceptions, appeal, and susceptibility to e-cigarette use. This protocol represent the first experiment.","We will estimate the effects of visual features often used in e-cigarette influencer marketing on social media on perceptions of influencer credibility, harm perceptions, appeal and susceptibility to e-cigarette use among adolescents. We will assess interaction of the perceived age of influencers (young-looking vs older-looking) with the following features of influencer marketing, using two survey-based experiments: Experiment 1 will assess the effects of theme or social context appeal, i.e., use of generally positively perceived lifestyle contexts (e.g., healthy lifestyle, entertainment) alongside e-cigarette marketing.",[19],"Vaping",[],"INTERVENTIONAL",[23],"NA",{"count":25,"type":26},6000,"ESTIMATED",[28],{"type":14,"name":29,"description":30,"armGroupLabels":31},"Exposure to Influencer Age and Context Variations in E-Cigarette Marketing","Exposure to promotional e-cigarette videos where influencers' age appearance (manipulated via an AI-based age filter) and the situational context alongside e-cigarette promotion (manipulated by background settings) are systematically varied. The videos will be embedded within an online survey platform, immediately preceding the outcome assessment.",[32,33,34,35,36,37,38,39,40,41,42,43],"Experimental: Videos featuring older influencers promoting e-cigarettes alone","Experimental: Videos featuring older influencers promoting e-cigarettes alongside avatar","Experimental: Videos featuring older influencers promoting e-cigarettes alongside entertainment","Experimental: Videos featuring older influencers promoting e-cigarettes alongside fashion","Experimental: Videos featuring older influencers promoting e-cigarettes alongside fitness","Experimental: Videos featuring two neutral profiles of older influencers","Experimental: Videos featuring two neutral profiles of younger influencers","Experimental: Videos featuring young influencers promoting e-cigarettes alone","Experimental: Videos featuring young influencers promoting e-cigarettes alongside avatar","Experimental: Videos featuring young influencers promoting e-cigarettes alongside entertainment","Experimental: Videos featuring young influencers promoting e-cigarettes alongside fashion","Experimental: Videos featuring young influencers promoting e-cigarettes alongside fitness",[45,49,52,55],{"measure":46,"description":47,"timeFrame":48},"Harm Perceptions of e-cigarettes","Responses to one question adapted from PATH, \"Based on the videos you just watched, do you think using e-cigarettes for vaping nicotine is harmful to your health?\" The outcome was assessed on the 5-point ordinal scale with the following response choices: Not at all harmful, slightly harmful, somewhat harmful, very harmful, extremely harmful.","Assessed 10 times immediately after each of the 10 videos during the 15-minute-long survey-based experiment",{"measure":50,"description":51,"timeFrame":48},"Perceived appeal of e-cigarettes","Responses to the following questions: using e-cigarette is: not cool\u002Fcool, unattractive\u002Fattractive were assessed on the 7-point semantic differential scale with the word pairs anchored at each end. The scale was adapted from prior research. The items were combined (by summing all the non-missing values of the items) into one variable (α=0.94).",{"measure":53,"description":54,"timeFrame":48},"Susceptibility to e-cigarette use","Susceptibility to e-cigarette use was measured (among never-users of e-cigarettes), using the validated three-item scale (indicating peer influence, intention, and curiosity about e-cigarette use) adapted from PATH, and combined into one variable (α=0.93). Consistent with prior research, the measure was dichotomized with responses \"definitely not\" to all items being coded as \"not susceptible\" and responses \"probably not,\" \"probably yes\", or \"definitely yes\" being coded as \"susceptible.",{"measure":56,"description":57,"timeFrame":48},"Perceived influencer credibility","Perceived influencer credibility (i.e., honesty, trustworthiness, knowledge) were assessed using a 0 (e.g., dishonest) -100 (e.g., honest) scale that has been validated in prior research.",[],"ALL","14 Years","17 Years",{"inclusion":63,"exclusion":66,"raw_text":67},[64,65],"14-17 years of age,","English fluency,",[64,65],"Inclusion Criteria:\n\n* 14-17 years of age,\n* English fluency,\n\nExclusion Criteria:\n\nNot meeting the following criteria:\n\n* 14-17 years of age,\n* English fluency,",[69],"CHILD",[71],{"facility":13,"city":72,"state":73,"zip":74,"country":75,"contacts":76,"geoPoint":82},"Los Angeles","California","90032","United States",[77],{"name":78,"role":79,"phone":80,"email":81},"Jennifer Unger, PhD","CONTACT","3233330580","unger@usc.edu",{"lat":83,"lon":84},34.05223,-118.24368,[86,89],{"name":87,"role":79,"phone":88,"email":81},"Jennifer B Unger, PI, PhD","(323) 442-7200",{"name":90,"role":79,"phone":88,"email":91},"Julia Vassey, PhD","vassey@usc.edu",[93],{"name":94,"affiliation":13,"role":95},"Jennifer B Unger, PhD","PRINCIPAL_INVESTIGATOR",[],[],{"nct_id":4,"conditions":99,"biomarkers":100},[19],[],{"nct_id":4,"found":102,"summary":103,"prompt_version":113},true,{"design":104,"status":105,"heading":106,"summary":107,"follow_up":108,"word_count":109,"commitments":110,"compensation":111,"drugs_mentioned":112},"This is an interventional study involving 6,000 participants. It uses a survey-based experiment where participants are exposed to different e-cigarette marketing videos.","completed","E-cigarette Social Media Marketing and Youth Perceptions","This study is looking at how social media marketing for e-cigarettes affects young people. Researchers want to understand how different ways of presenting e-cigarettes online, like using influencers who look younger or older, and showing e-cigarettes in different situations (like with healthy lifestyles or entertainment), change how teenagers view e-cigarettes. Specifically, they will look at how these marketing techniques influence whether teenagers think e-cigarettes are harmful, how appealing they find them, and if they might be more likely to try them. This study is for young people aged 14 to 17 who speak English. The study aims to enroll 6,000 participants and is currently unclear if it's recruiting.","Your perceptions will be assessed immediately after each of the 10 videos during the 15-minute survey. There is no mention of follow-up after the survey.",108,"You would watch 10 e-cigarette videos during a 15-minute survey. After each video, you would answer questions about your perceptions of e-cigarettes.","Not stated in the trial record.",[],"v2"]