[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07714044":3,"trial-entities:NCT07714044":93,"trial-summary:NCT07714044":97},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":28,"study_type":39,"primary_purpose":40,"phases":41,"enrollment_info":42,"interventions":45,"primary_outcomes":46,"secondary_outcomes":51,"sex":52,"minimum_age":53,"maximum_age":54,"healthy_volunteers":55,"eligibility_criteria":56,"std_ages":66,"locations":69,"central_contacts":87,"overall_officials":89,"references":91,"see_also_links":92},"NCT07714044","Pro2026000226","Rutgers University Study of the Genetics of Blood Cancers","The Rutgers University Study of the Genetics of Blood Cancers","NOT_YET_RECRUITING","2029-08","2026-07","2026-07-20","2026-08","Rutgers, The State University of New Jersey","OTHER",false,"The goal of this study is to enroll at least 10,000 participants nationally including affecteds and unaffecteds via online study portal, collect surveys online and a saliva sample through the mail, sequence DNA, and conduct genetic analyses to identify novel variants and further study known variants associated with leukemia, lymphoma, myeloma and other blood cancers.","This is an online research study to learn more about how genes affect your risk of blood cancers. No office visit is required and in return, participants may receive information about their genetic ancestry for free. This study will increase our understanding of the genetic basis of blood cancers, which is a crucial step in drug development to improve current treatment options. We seek a diverse population because diversity among participants maximizes the usefulness of the data. Participants will use our online study portal to answer questions about their health and provide their DNA via a saliva sample using a pre-paid mailer. Participation takes approximately 20 minutes. Participants will be invited to share data from their electronic health records, but this is not required for study participation. We keep participants engaged with short monthly newsletters.",[19,20,21,22,23,24,25,26,27],"Blood Cancers","Blood Cancer","Leukemia","Lymphoma","Myeloma","Hematologic Cancer","Hematologic Malignancies","Hematologic Neoplasm","Hematologic Tumors",[29,30,31,32,33,34,35,36,37,38],"genetics","blood cancer","blood cancers","leukemia","lymphoma","myeloma","hematologic cancer","hematologic malignancy","hematologic tumor","hematologic neoplasm","OBSERVATIONAL",null,[],{"count":43,"type":44},10000,"ESTIMATED",[],[47],{"measure":48,"description":49,"timeFrame":50},"Genetic risk variants associated with blood cancer","Genetic factors will be measured through whole exome sequencing and genome-wide genotyping array, and then correlated with blood cancer subtype.","2 years",[],"ALL","18 Years","110 Years",true,{"inclusion":57,"exclusion":64,"raw_text":65},[58,59,60,61,62,63],"age 18 years or older","currently living in the United States","have access to the internet and a computer, laptop, tablet or smartphone","willing to provide written informed consent for participation","willing to provide DNA via a saliva sample using a collection kit mailed to your home","willing to complete a survey with questions about health related to the study of blood cancer.",[],"Inclusion Criteria:\n\n* age 18 years or older\n* currently living in the United States\n* have access to the internet and a computer, laptop, tablet or smartphone\n* willing to provide written informed consent for participation\n* willing to provide DNA via a saliva sample using a collection kit mailed to your home\n* willing to complete a survey with questions about health related to the study of blood cancer.\n\nExclusion Criteria:\n\n* Not able to meet or fulfill any of the inclusion criteria",[67,68],"ADULT","OLDER_ADULT",[70],{"facility":71,"city":72,"state":73,"zip":74,"country":75,"contacts":76,"geoPoint":84},"Rutgers University","Piscataway","New Jersey","08854","United States",[77,82],{"name":78,"role":79,"phone":80,"email":81},"Tara Matise, PhD","CONTACT","848-445-3125","rugcc@rutgers.edu",{"name":78,"role":83},"PRINCIPAL_INVESTIGATOR",{"lat":85,"lon":86},40.49927,-74.39904,[88],{"name":78,"role":79,"phone":80,"email":81},[90],{"name":78,"affiliation":71,"role":83},[],[],{"nct_id":4,"conditions":94,"biomarkers":96},[26,21,22,95],"Multiple Myeloma",[],{"nct_id":4,"found":55,"summary":98,"prompt_version":107},{"design":99,"status":100,"heading":6,"summary":101,"follow_up":102,"word_count":103,"commitments":104,"compensation":105,"drugs_mentioned":106},"This is an observational study aiming to enroll 10,000 participants. It is an online research study.","completed","This study from Rutgers University is looking at the genes that might affect your risk of developing blood cancers like leukemia, lymphoma, and myeloma. There are no specific treatments or drugs being tested. Instead, researchers want to find new genetic differences and learn more about known ones related to these cancers. You can join if you are 18 or older, live in the US, and have internet access. The goal is to enroll 10,000 people. Success for this study means identifying genetic risk variants (changes in your genes that might increase your risk) associated with blood cancer within two years. The current recruitment status is unclear.","Genetic risk variants associated with blood cancer will be measured at 2 years.",106,"You will complete an online survey about your health and provide a saliva sample using a kit mailed to your home. This takes about 20 minutes.","You may receive information about your genetic ancestry for free. Not stated in the trial record if there is other compensation.",[],"v2"]