[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07716319":3,"trial-entities:NCT07716319":130,"trial-summary:NCT07716319":133},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":7,"overall_status":8,"completion_date":9,"status_verified_date":10,"last_update_date":11,"start_date":12,"sponsor_name":13,"lead_sponsor_class":14,"has_dmc":15,"brief_summary":16,"detailed_description":17,"conditions":18,"keywords":25,"study_type":34,"primary_purpose":14,"phases":35,"enrollment_info":37,"interventions":40,"primary_outcomes":56,"secondary_outcomes":66,"sex":85,"minimum_age":86,"maximum_age":87,"healthy_volunteers":15,"eligibility_criteria":88,"std_ages":106,"locations":108,"central_contacts":124,"overall_officials":127,"references":128,"see_also_links":129},"NCT07716319","2026-0704","Comparison Between Eccentric Hamstring Training and Sprint-Specific Training","Comparison Between Eccentric Hamstring Strength Training and Sprint-Specific Training on Muscle Hypertrophy, Strength, Power, and Sprint Performance in Club Sport Collegiate Athletes","NOT_YET_RECRUITING","2027-09","2026-07","2026-07-21","2026-09","University of Wisconsin, Madison","OTHER",true,"The purpose of this study is to compare the effects of an intensity-, volume-, and time under tension-matched eccentric hamstring exercise intervention with the Romanian deadlift (RDL) and the Nordic hamstring exercise (NHE) to a sprint-specific training program on hamstring muscle architecture, volume, sprint performance, strength, and power.\n\nParticipants will be assigned to complete one of the 3 hamstring interventions for 10 weeks.","Prior to the intervention, participants will undergo baseline testing which will include a) ultrasound imaging of the hamstrings muscles for measures of biceps femoris long head fascicle length, pennation angle, muscle thickness, anatomical cross-sectional area, and muscle volume b) passive and active ranges of motion, c) 3 repetition maximum (3RM) RDL strength, d) peak NHE force, e) countermovement jump height, f) broad jump distance, g) Pro Agility change of direction, and h) a 60 m sprint with sprint kinematics assessed via inertial measurement units.\n\nParticipants will be randomly assigned to either the RDL, NHE, or sprint training group. After randomization, each participant will undergo the intervention program based upon their group allocation.\n\nPerformance testing and imaging will be repeated mid-intervention, following the intervention, and after 2 weeks of deloading.",[19,20,21,22,23,24],"Healthy Adult","Athlete","Exercise Training","Sport","Running","Ultrasound Imaging",[26,27,28,29,30,31,32,33],"strength","agility","sprint","hypertrophy","countermovement jump","fascicle length","hamstring","range of motion","INTERVENTIONAL",[36],"NA",{"count":38,"type":39},90,"ESTIMATED",[41,46,51],{"type":14,"name":42,"description":43,"armGroupLabels":44},"RDL","The RDL will be performed with a 6 second eccentric component with the athlete returning to the start position with a maximal concentric hip extension.",[45],"Romanian dead lift (RDL) group",{"type":14,"name":47,"description":48,"armGroupLabels":49},"NHE","The NHE will be performed with a 6 second eccentric component.",[50],"Nordic hamstring exercise (NHE) group",{"type":14,"name":52,"description":53,"armGroupLabels":54},"Sprint testing","The sprint training program will be performed twice per week with the first day of training focused on shorter distances to focus on acceleration and the second training day focused on maximal velocity. The relative efforts and distances for each training day will mimic a similar prescription to that of the resistance training program.",[55],"Sprint group",[57,60,62,64],{"measure":58,"timeFrame":59},"Change in fascicle length (FL)","Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)",{"measure":61,"timeFrame":59},"Change in muscle cross-sectional area (CSA)",{"measure":63,"timeFrame":59},"Change in muscle volume",{"measure":65,"timeFrame":59},"Change in pennation angle (PA)",[67,70,73,75,77,79,81,83],{"measure":68,"description":69,"timeFrame":59},"Change in eccentric strength","Eccentric hamstring strength of each limb will be assessed during the hamstring exercise.",{"measure":71,"description":72,"timeFrame":59},"Change in inertial measurement units (IMU)-based sprinting biomechanics","Sprinting biomechanics will be assessed using seven IMUs (sacrum, both thighs, both shanks, both feet). Lower extremity joint motions referenced to upright stance will be calculated throughout an on-field sprint and other football drills.",{"measure":74,"timeFrame":59},"Change in countermovement jump (CMJ) performance",{"measure":76,"timeFrame":59},"Change in standing broad jump (SBJ) performance",{"measure":78,"timeFrame":59},"Change in change of direction (CoD) performance",{"measure":80,"timeFrame":59},"Change in range of motion (ROM) performance",{"measure":82,"timeFrame":59},"Change in hip flexion",{"measure":84,"timeFrame":59},"Change in anterior pelvic tilt","ALL","18 Years","25 Years",{"inclusion":89,"exclusion":98,"raw_text":105},[90,91,92,93,94,95,96,97],"Age 18-25 years","Actively participating in a club team","\\>6 months experience with resistance training","Minimum of 1 year experience at the high school level in organized team sport","No history of hamstring injury within the last 6 months","No history of major lower extremity surgery (including back)","No acute musculoskeletal injury to the lower extremity","Not currently pregnant",[99,100,101,102,103,104],"Unable to refrain from resistance training outside the study","Unable to make at least 80% of the training sessions","Hamstring injury in the last 6 months","History of major lower extremity surgery (including back)","Acute musculoskeletal injury to the lower extremity","Currently pregnant","Inclusion Criteria:\n\n* Age 18-25 years\n* Actively participating in a club team\n* \\>6 months experience with resistance training\n* Minimum of 1 year experience at the high school level in organized team sport\n* No history of hamstring injury within the last 6 months\n* No history of major lower extremity surgery (including back)\n* No acute musculoskeletal injury to the lower extremity\n* Not currently pregnant\n\nExclusion Criteria:\n\n* Unable to refrain from resistance training outside the study\n* Unable to make at least 80% of the training sessions\n* Hamstring injury in the last 6 months\n* History of major lower extremity surgery (including back)\n* Acute musculoskeletal injury to the lower extremity\n* Currently pregnant",[107],"ADULT",[109],{"facility":110,"city":111,"state":112,"zip":113,"country":114,"contacts":115,"geoPoint":121},"University of Wisconsin - Madison","Madison","Wisconsin","53705","United States",[116],{"name":117,"role":118,"phone":119,"email":120},"Scott K Crawford, PhD","CONTACT","608-265-1308","skcrawford2@wisc.edu",{"lat":122,"lon":123},43.07305,-89.40123,[125],{"name":117,"role":118,"phone":126,"email":120},"608) 265-1308",[],[],[],{"nct_id":4,"conditions":131,"biomarkers":132},[20,19],[],{"nct_id":4,"found":15,"summary":134,"prompt_version":144},{"design":135,"status":136,"heading":137,"summary":138,"follow_up":139,"word_count":140,"commitments":141,"compensation":142,"drugs_mentioned":143},"This interventional study plans to enroll 90 participants who will be randomly assigned to one of three training groups: RDL, NHE, or sprint training.","completed","Comparing Hamstring Exercises and Sprint Training for Athletes","This study is comparing different ways to train your hamstring muscles. Researchers want to see if specific eccentric hamstring exercises, like the Romanian Deadlift (RDL) or Nordic Hamstring Exercise (NHE), or a sprint-specific training program, are better at changing hamstring muscle size and improving sprint performance, strength, and power. You could be eligible if you are a healthy adult athlete between 18 and 25 years old, have experience with resistance training and team sports, and haven't had a recent hamstring injury or major lower body surgery. The study aims to find out which training method leads to the most improvement in hamstring muscle structure (like fascicle length and muscle volume) and athletic performance. The current recruitment status is unclear.","You will be followed for 2 weeks after the 10-week intervention period to assess changes after de-training.",119,"You would undergo baseline testing, participate in a 10-week training program based on your assigned group, and repeat performance testing and imaging mid-intervention, after the intervention, and after a 2-week deloading period.","Not stated in the trial record.",[42,47],"v2"]