[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07725198":3,"trial-entities:NCT07725198":83,"trial-summary:NCT07725198":87},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":14,"conditions":16,"keywords":19,"study_type":20,"primary_purpose":21,"phases":22,"enrollment_info":24,"interventions":27,"primary_outcomes":34,"secondary_outcomes":39,"sex":46,"minimum_age":47,"maximum_age":48,"healthy_volunteers":49,"eligibility_criteria":50,"std_ages":59,"locations":62,"central_contacts":78,"overall_officials":80,"references":81,"see_also_links":82},"NCT07725198","2025-11","Immediate Neuromuscular Responses of the Obliquus Capitis Inferior Following Upper Cervical Manual Therapy","RECRUITING","2027-06-01","2026-07","2026-07-24","2025-05-01","Florida Gulf Coast University","OTHER",null,"This study used a prospective, randomized, repeated-measures experimental design to investigate the immediate effects of two upper cervical manual therapy interventions on craniovertebral angle (CVA), clinician-perceived atlas position, and musculoskeletal ultrasound-derived obliquus capitis inferior (OCI) muscle morphology",[17,18],"Head and Neck","Headache",[],"INTERVENTIONAL","TREATMENT",[23],"NA",{"count":25,"type":26},80,"ESTIMATED",[28],{"type":13,"name":29,"description":30,"armGroupLabels":31},"Thrust long-axis manipulation of C1-C2","One thrust manipulation is provided in the thrust group. a 5 second long axis hold traction of C1-C2 was repeated 3 times in the mobilization group",[32,33],"Long axis thrust manipulation group","Long axis thrust mobilization group",[35],{"measure":36,"description":37,"timeFrame":38},"MSK Ultrasound","MSK Ultrasound measure of the Obliquues Capitis inferior muscle lenght and width","before intervention, immediately after, and 24 hours after intervention",[40,43],{"measure":41,"description":42,"timeFrame":38},"Atlas position","Atlas position relative to the head measured wth palpation of C1 transverse process",{"measure":44,"description":45,"timeFrame":38},"Craniovertebral angle","Measure of the Craniovertebral angle using photography","ALL","18 Years","65 Years",true,{"inclusion":51,"exclusion":55,"raw_text":58},[52,53,54],"read and understand English","no previous history of cervical spine surgery or traumatic cervical injury","no contraindications to cervical manual therapy",[56,57],"any absolute contraindications to cervical manipulation","any other medical condition considered unsafe for manual therapy.","Inclusion Criteria:\n\n* read and understand English\n* no previous history of cervical spine surgery or traumatic cervical injury\n* no contraindications to cervical manual therapy\n\nExclusion Criteria:\n\n* any absolute contraindications to cervical manipulation\n* any other medical condition considered unsafe for manual therapy.",[60,61],"ADULT","OLDER_ADULT",[63],{"facility":64,"status":7,"city":65,"state":66,"zip":67,"country":68,"contacts":69,"geoPoint":75},"Florida Gulf Coast University Marieb Hall 101","Fort Myers","Florida","33965","United States",[70],{"name":71,"role":72,"phone":73,"email":74},"Rob Sillevis, PhD","CONTACT","239-7454312","rsillevis@fgcu.edu",{"lat":76,"lon":77},26.62168,-81.84059,[79],{"name":71,"role":72,"phone":73,"email":74},[],[],[],{"nct_id":4,"conditions":84,"biomarkers":86},[18,85],"Head and Neck Carcinoma of Unknown Primary",[],{"nct_id":4,"found":49,"summary":88,"prompt_version":97},{"design":89,"status":90,"heading":6,"summary":91,"follow_up":92,"word_count":93,"commitments":94,"compensation":95,"drugs_mentioned":96},"This is an interventional study with a prospective, randomized design, meaning participants are randomly assigned to one of the two treatment groups. The study plans to enroll 80 participants.","completed","This study is looking at the immediate effects of two types of upper neck (cervical) manual therapy on people with head and neck pain or headaches. Researchers are testing a \"Thrust long-axis manipulation of C1-C2\" and a \"5 second long axis hold traction of C1-C2\" to see how they affect the obliquus capitis inferior (OCI) muscle, which is a small muscle in your neck. They will use musculoskeletal ultrasound to measure changes in this muscle before, immediately after, and 24 hours after the treatment. You may be able to join if you are between 18 and 65 years old, can read English, and have no history of neck surgery or serious neck injury. The study aims to enroll 80 participants, but its current recruitment status is unclear.","Participants will be followed for 24 hours after the intervention, with measurements taken at that time.",127,"You would receive one of two manual therapy interventions: either a single thrust manipulation or three 5-second long axis hold tractions. Measurements will be taken before the intervention, immediately after, and 24 hours later.","Not stated in the trial record.",[29],"v2"]