[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"trial:NCT07725250":3,"trial-entities:NCT07725250":98,"trial-summary:NCT07725250":101},{"id":4,"nct_id":4,"org_study_id":5,"brief_title":6,"official_title":6,"overall_status":7,"completion_date":8,"status_verified_date":9,"last_update_date":10,"start_date":11,"sponsor_name":12,"lead_sponsor_class":13,"has_dmc":14,"brief_summary":15,"detailed_description":16,"conditions":17,"keywords":19,"study_type":23,"primary_purpose":24,"phases":25,"enrollment_info":27,"interventions":30,"primary_outcomes":46,"secondary_outcomes":50,"sex":51,"minimum_age":52,"maximum_age":16,"healthy_volunteers":53,"eligibility_criteria":54,"std_ages":65,"locations":68,"central_contacts":87,"overall_officials":90,"references":96,"see_also_links":97},"NCT07725250","8577_RCT","Behavioral Interventions Combining AI\u002FML and Personalized Medicine to Reduce Cardiovascular Risk - Randomized Controlled Trial","RECRUITING","2027-04-30","2026-07","2026-07-24","2026-04-10","National Bureau of Economic Research, Inc.","OTHER",true,"This study evaluates a new digital health program that uses artificial intelligence (AI) to help patients lower their blood pressure through personalized lifestyle recommendations. The program collects information about patients' daily habits and blood pressure readings, then uses AI to suggest lifestyle changes that may work best for each person. The study will measure how well this program works across different groups of patients and aims to improve the program design to make it more effective and easier to use. The program will be offered to diverse patients at UC San Diego Health, including people of different ages, genders, races\u002Fethnicities, and economic backgrounds, as part of their regular healthcare services.",null,[18],"Hypertension",[20,21,22],"lifestyle recommendations","AI\u002FML","personalized medicine","INTERVENTIONAL","TREATMENT",[26],"NA",{"count":28,"type":29},3000,"ESTIMATED",[31,38,42],{"type":13,"name":32,"description":33,"armGroupLabels":34},"Digital heath tool","Digital health tool of patient-tailored lifestyle recommendations for blood pressure maintenance. Current \"simplified\" remote patient monitoring program referred to as \"P1000.\" Requires daily blood pressure readings only.",[35,36,37],"RCT Arm A: Digital health tool","RCT Arm B.1: Digital health tool + low-intensity recommendations","RCT Arm B.2: Digital health tool + high-intensity recommendations",{"type":13,"name":39,"description":40,"armGroupLabels":41},"Low-intensity recommendation","AI-enhanced lifestyle and health recommendations provided weekly. This requires blood pressure readings, as well as passive readings, (e.g. sleep, movement), and a daily questionnaire.",[36],{"type":13,"name":43,"description":44,"armGroupLabels":45},"High-intensity recommendation","AI-enhanced lifestyle and health recommendations provided weekly, plus daily reminders. This requires blood pressure readings, as well as passive readings, (e.g. sleep, movement), and a daily questionnaire.",[37],[47],{"measure":48,"timeFrame":49},"Systolic blood pressure measurement","6 months",[],"ALL","18 Years",false,{"inclusion":55,"exclusion":59,"raw_text":64},[56,57,58],"Stage I-II hypertension (average clinical readings of blood pressure over 140\u002F90)","Adequate decisional capacity to make a choice about participating in this research study","Fully ambulatory (not requiring assistive device such as a cane, wheelchair, walker, etc.)",[60,61,62,63],"Pregnancy","Under age 18 years","Institutionalized individuals who are likely to be vulnerable","Dependent on supplemental oxygen","Inclusion Criteria:\n\n* Stage I-II hypertension (average clinical readings of blood pressure over 140\u002F90)\n* Adequate decisional capacity to make a choice about participating in this research study\n* Fully ambulatory (not requiring assistive device such as a cane, wheelchair, walker, etc.)\n\nExclusion Criteria:\n\n* Pregnancy\n* Under age 18 years\n* Institutionalized individuals who are likely to be vulnerable\n* Dependent on supplemental oxygen",[66,67],"ADULT","OLDER_ADULT",[69],{"facility":70,"status":7,"city":71,"state":72,"zip":73,"country":74,"contacts":75,"geoPoint":84},"University of California, San Diego","La Jolla","California","92093","United States",[76,81],{"name":77,"role":78,"phone":79,"email":80},"Amanda Walker","CONTACT","617-588-1445","Alw038@health.ucsd.edu",{"name":82,"role":78,"email":83},"Ross Graham","rograham@health.ucsd.edu",{"lat":85,"lon":86},32.84727,-117.2742,[88,89],{"name":77,"role":78,"phone":79,"email":80},{"name":82,"role":78,"email":83},[91,94],{"name":92,"affiliation":12,"role":93},"Itzik Fadlon","PRINCIPAL_INVESTIGATOR",{"name":95,"affiliation":70,"role":93},"Ming Tai-Seale",[],[],{"nct_id":4,"conditions":99,"biomarkers":100},[18],[],{"nct_id":4,"found":14,"summary":102,"prompt_version":112},{"design":103,"status":104,"heading":105,"summary":106,"follow_up":107,"word_count":108,"commitments":109,"compensation":110,"drugs_mentioned":111},"This is an interventional study planning to enroll 3000 participants. It compares different levels of digital health recommendations.","completed","Digital Health Program for High Blood Pressure","This study is testing a new digital health program that uses artificial intelligence (AI) to help people with high blood pressure (hypertension) lower their readings. The program offers personalized lifestyle recommendations. You could join if you are 18 or older, have Stage I-II hypertension (blood pressure over 140\u002F90), and can walk without assistance. The study will look at how much your systolic blood pressure (the top number) changes after 6 months to see if the program works. The current recruitment status is unclear, but the study plans to enroll 3000 people.","Your systolic blood pressure will be measured at 6 months after starting the program.",91,"Depending on the group, you would take daily blood pressure readings. Some groups also require passive readings (like sleep and movement) and a daily questionnaire.","Not stated in the trial record.",[],"v2"]